| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 14595* | 2021 |
| Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson's disease TF Outeiro, E Kontopoulos, SM Altmann, I Kufareva, KE Strathearn, ... science 317 (5837), 516-519, 2007 | 1331 | 2007 |
| Yeast cells provide insight into alpha-synuclein biology and pathobiology TF Outeiro, S Lindquist Science 302 (5651), 1772-1775, 2003 | 1081 | 2003 |
| α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells C Hansen, E Angot, AL Bergström, JA Steiner, L Pieri, G Paul, TF Outeiro, ... The Journal of clinical investigation 121 (2), 715-725, 2011 | 1035 | 2011 |
| Formation of toxic oligomeric α-synuclein species in living cells TF Outeiro, P Putcha, JE Tetzlaff, R Spoelgen, M Koker, F Carvalho, ... PloS one 3 (4), e1867, 2008 | 556 | 2008 |
| Yeast genes that enhance the toxicity of a mutant huntingtin fragment or α-synuclein S Willingham, TF Outeiro, MJ DeVit, SL Lindquist, PJ Muchowski Science 302 (5651), 1769-1772, 2003 | 549 | 2003 |
| SIRT1 and SIRT2: emerging targets in neurodegeneration G Donmez, TF Outeiro EMBO molecular medicine 5 (3), 344-352, 2013 | 486 | 2013 |
| Dementia with Lewy bodies: an update and outlook TF Outeiro, DJ Koss, D Erskine, L Walker, M Kurzawa-Akanbi, D Burn, ... Molecular neurodegeneration 14 (1), 5, 2019 | 485 | 2019 |
| Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration B Mollenhauer, V Cullen, I Kahn, B Krastins, TF Outeiro, I Pepivani, J Ng, ... Experimental neurology 213 (2), 315-325, 2008 | 483 | 2008 |
| A biological classification of Parkinson's disease: the SynNeurGe research diagnostic criteria GU Höglinger, CH Adler, D Berg, C Klein, TF Outeiro, W Poewe, ... The Lancet Neurology 23 (2), 191-204, 2024 | 477 | 2024 |
| Alpha-synuclein: from secretion to dysfunction and death O Marques, TF Outeiro Cell death & disease 3 (7), e350-e350, 2012 | 422 | 2012 |
| Glyoxal as an alternative fixative to formaldehyde in immunostaining and super‐resolution microscopy KN Richter, NH Revelo, KJ Seitz, MS Helm, D Sarkar, RS Saleeb, ... The EMBO journal 37 (1), 139-159, 2018 | 360 | 2018 |
| Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington’s and Parkinson’s diseases RA Bodner, TF Outeiro, S Altmann, MM Maxwell, SH Cho, BT Hyman, ... Proceedings of the National Academy of Sciences 103 (11), 4246-4251, 2006 | 359 | 2006 |
| Structure, function and toxicity of alpha‐synuclein: the Bermuda triangle in synucleinopathies A Villar‐Piqué, T Lopes da Fonseca, TF Outeiro Journal of neurochemistry 139, 240-255, 2016 | 345 | 2016 |
| Protein phosphorylation in neurodegeneration: friend or foe? S Tenreiro, K Eckermann, TF Outeiro Frontiers in molecular neuroscience 7, 42, 2014 | 338 | 2014 |
| Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation MJ Diógenes, RB Dias, DM Rombo, HV Miranda, F Maiolino, P Guerreiro, ... Journal of Neuroscience 32 (34), 11750-11762, 2012 | 335 | 2012 |
| α-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B DG Ferreira, M Temido-Ferreira, H Vicente Miranda, VL Batalha, ... Nature neuroscience 20 (11), 1569-1579, 2017 | 323 | 2017 |
| Convergence of miRNA expression profiling, α-synuclein interacton and GWAS in Parkinson's disease M Martins, A Rosa, LC Guedes, BV Fonseca, K Gotovac, S Violante, ... PloS one 6 (10), e25443, 2011 | 323 | 2011 |
| Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation DF Lázaro, EF Rodrigues, R Langohr, H Shahpasandzadeh, T Ribeiro, ... PLoS genetics 10 (11), e1004741, 2014 | 287 | 2014 |
| Emerging role of sirtuin 2 in the regulation of mammalian metabolism P Gomes, TF Outeiro, C Cavadas Trends in pharmacological sciences 36 (11), 756-768, 2015 | 279 | 2015 |
Diana F. LázaroCenter for Neurodegenerative Disease Research, UPennVerified email at pennmedicine.upenn.edu
