| The biology, function, and biomedical applications of exosomes R Kalluri, VS LeBleu Science 367 (6478), eaau6977, 2020 | 10523 | 2020 |
| Glypican-1 identifies cancer exosomes and detects early pancreatic cancer SA Melo, LB Luecke, C Kahlert, AF Fernandez, ST Gammon, J Kaye, ... Nature 523 (7559), 177-182, 2015 | 3221 | 2015 |
| Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival BC Özdemir, T Pentcheva-Hoang, JL Carstens, X Zheng, CC Wu, ... Cancer cell 25 (6), 719-734, 2014 | 2776 | 2014 |
| Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer S Kamerkar, VS LeBleu, H Sugimoto, S Yang, CF Ruivo, SA Melo, JJ Lee, ... Nature 546 (7659), 498-503, 2017 | 2761 | 2017 |
| B cells and tertiary lymphoid structures promote immunotherapy response BA Helmink, SM Reddy, J Gao, S Zhang, R Basar, R Thakur, K Yizhak, ... Nature 577 (7791), 549-555, 2020 | 2570 | 2020 |
| Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer X Zheng, JL Carstens, J Kim, M Scheible, J Kaye, H Sugimoto, CC Wu, ... Nature 527 (7579), 525-530, 2015 | 2372 | 2015 |
| PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis VS LeBleu, JT O’Connell, KN Gonzalez Herrera, H Wikman, K Pantel, ... Nature cell biology 16 (10), 992-1003, 2014 | 1596 | 2014 |
| Origin and function of myofibroblasts in kidney fibrosis VS LeBleu, G Taduri, J O'connell, Y Teng, VG Cooke, C Woda, ... Nature medicine 19 (8), 1047-1053, 2013 | 1508 | 2013 |
| Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis S Lovisa, VS LeBleu, B Tampe, H Sugimoto, K Vadnagara, JL Carstens, ... Nature medicine 21 (9), 998-1009, 2015 | 1050 | 2015 |
| Structure and function of basement membranes VS LeBleu, B MacDonald, R Kalluri Experimental biology and medicine 232 (9), 1121-1129, 2007 | 901 | 2007 |
| Generation and testing of clinical-grade exosomes for pancreatic cancer M Mendt, S Kamerkar, H Sugimoto, KM McAndrews, CC Wu, M Gagea, ... JCI insight 3 (8), e99263, 2018 | 833 | 2018 |
| Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer JL Carstens, P Correa de Sampaio, D Yang, S Barua, H Wang, A Rao, ... Nature communications 8 (1), 15095, 2017 | 700 | 2017 |
| Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression H Laklai, YA Miroshnikova, MW Pickup, EA Collisson, GE Kim, AS Barrett, ... Nature medicine 22 (5), 497-505, 2016 | 668 | 2016 |
| Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway VG Cooke, VS LeBleu, D Keskin, Z Khan, JT O'Connell, Y Teng, ... Cancer cell 21 (1), 66-81, 2012 | 622 | 2012 |
| A peek into cancer-associated fibroblasts: origins, functions and translational impact VS LeBleu, R Kalluri Disease models & mechanisms 11 (4), dmm029447, 2018 | 613 | 2018 |
| Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer Y Chen, J Kim, S Yang, H Wang, CJ Wu, H Sugimoto, VS LeBleu, ... Cancer cell 39 (4), 548-565. e6, 2021 | 567 | 2021 |
| Cell growth and size homeostasis in proliferating animal cells A Tzur, R Kafri, VS LeBleu, G Lahav, MW Kirschner Science 325 (5937), 167-171, 2009 | 511 | 2009 |
| TGF-β1–containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis FT Borges, SA Melo, BC Özdemir, N Kato, I Revuelta, CA Miller, ... Journal of the American Society of Nephrology 24 (3), 385-392, 2013 | 506 | 2013 |
| VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization JT O'Connell, H Sugimoto, VG Cooke, BA MacDonald, AI Mehta, ... Proceedings of the National Academy of Sciences 108 (38), 16002-16007, 2011 | 421 | 2011 |
| Biomolecular characterization and protein sequences of the Campanian hadrosaur B. canadensis MH Schweitzer, W Zheng, CL Organ, R Avci, Z Suo, LM Freimark, ... science 324 (5927), 626-631, 2009 | 318 | 2009 |
Raghu KalluriProfessor of Cancer Biology, MD Anderson Cancer CenterVerified email at mdanderson.org
