| Identification of functional heterogeneity of carcinoma-associated fibroblasts with distinct IL6-mediated therapy resistance in pancreatic cancer KM McAndrews, Y Chen, JK Darpolor, X Zheng, S Yang, JL Carstens, B Li, ... Cancer discovery 12 (6), 1580-1597, 2022 | 257 | 2022 |
| KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells KK Mahadevan, KM McAndrews, VS LeBleu, S Yang, H Lyu, B Li, ... Cancer Cell 41 (9), 1606-1620. e8, 2023 | 211 | 2023 |
| Therapeutic targeting of STAT3 with small interference RNAs and antisense oligonucleotides embedded exosomes in liver fibrosis M Tang, Y Chen, B Li, H Sugimoto, S Yang, C Yang, VS LeBleu, ... The FASEB Journal 35 (5), e21557, 2021 | 92 | 2021 |
| A novel drug repurposing approach for non-small cell lung cancer using deep learning B Li, C Dai, L Wang, H Deng, Y Li, Z Guan, H Ni PLoS One 15 (6), e0233112, 2020 | 70 | 2020 |
| VISDB: a manually curated database of viral integration sites in the human genome D Tang, B Li, T Xu, R Hu, D Tan, X Song, P Jia, Z Zhao Nucleic acids research 48 (D1), D633-D641, 2020 | 64 | 2020 |
| Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells KK Mahadevan, VS LeBleu, EV Ramirez, Y Chen, B Li, AM Sockwell, ... Developmental cell 58 (17), 1562-1577. e8, 2023 | 61 | 2023 |
| A novel machine learning algorithm selects proteome signature to specifically identify cancer exosomes B Li, FG Kugeratski, R Kalluri Elife 12, RP90390, 2024 | 54 | 2024 |
| Cell-type deconvolution analysis identifies cancer-associated myofibroblast component as a poor prognostic factor in multiple cancer types B Li, G Pei, J Yao, Q Ding, P Jia, Z Zhao Oncogene 40 (28), 4686-4694, 2021 | 51 | 2021 |
| αSMA+ fibroblasts suppress Lgr5+ cancer stem cells and restrain colorectal cancer progression KM McAndrews, K Vázquez-Arreguín, C Kwak, H Sugimoto, X Zheng, B Li, ... Oncogene 40 (26), 4440-4452, 2021 | 47 | 2021 |
| Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer KK Mahadevan, AM Dyevoich, Y Chen, B Li, H Sugimoto, AM Sockwell, ... Science 384 (6703), eadh4567, 2024 | 42 | 2024 |
| Identification of functional heterogeneity of carcinoma-associated fibroblasts with distinct IL6-mediated therapy resistance in pancreatic cancer. Cancer Discov. 2022; 12: 1580–97 KM McAndrews, Y Chen, JK Darpolor, X Zheng, S Yang, JL Carstens, B Li, ... DOI: https://doi. org/10.1158/2159-8290. CD-20-1484, 1580-1597, 0 | 37 | |
| Engineered exosomes targeting MYC reverse the proneural-mesenchymal transition and extend survival of glioblastoma AR Haltom, WE Hassen, J Hensel, J Kim, H Sugimoto, B Li, ... Extracellular vesicle 1, 100014, 2022 | 36 | 2022 |
| Acute Kidney Injury Instigates Malignant Renal Cell Carcinoma via CXCR2 in Mice with Inactivated Trp53 and Pten in Proximal Tubular Kidney Epithelial Cells X Zhou, F Xiao, H Sugimoto, B Li, KM McAndrews, R Kalluri Cancer research 81 (10), 2690-2702, 2021 | 21 | 2021 |
| Oncogenic KrasG12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination … KK Mahadevan, KM McAndrews, VS LeBleu, S Yang, H Lyu, B Li, ... bioRxiv, 2023.02. 15.528757, 2023 | 11 | 2023 |
| Mutations in the spike RBD of SARS-CoV-2 omicron variant may increase infectivity without dramatically altering the efficacy of current multi-dosage vaccinations B Li, X Lu, KM McAndrews, R Kalluri bioRxiv, 2021.12. 08.471688, 2021 | 10 | 2021 |
| Vascular heterogeneity of tight junction Claudins guides organotropic metastasis X Zhou, VS LeBleu, E Fletcher-Sananikone, J Kim, J Dai, B Li, CC Wu, ... Nature Cancer 5 (9), 1371-1389, 2024 | 9 | 2024 |
| Distinct small molecule inhibitors of Kras specifically prime CTLA4 blockade therapy to transcriptionally reprogram Tregs and overcome resistance to suppress pancreas cancer KK Mahadevan, AS Maldonado, B Li, AA Bickert, A Kapercyzk-Perdyan, ... bioRxiv, 2025.02. 28.640711, 2025 | 4 | 2025 |
| Antigen-presenting type-I conventional dendritic cells facilitate curative checkpoint blockade immunotherapy in pancreatic cancer KK Mahadevan, AM Dyevoich, Y Chen, B Li, H Sugimoto, AM Sockwell, ... bioRxiv, 2023.03. 05.531191, 2023 | 4 | 2023 |
| CDK8 remodels the tumor microenvironment to resist the therapeutic efficacy of targeted KRASG12D inhibition in pancreatic ductal adenocarcinoma KM McAndrews, KK Mahadevan, B Li, AM Sockwell, SJ Morse, PJ Kelly, ... bioRxiv, 2025.01. 29.635543, 2025 | 1 | 2025 |
| Abstract B082: Extinction of oncogenic Kras in genetic mouse models eradicates pancreatic cancer by inducing Fas-dependent apoptosis by CD8+ T cells VS LeBleu, KK Mahadevan, EV Ramirez, Y Chen, B Li, AM Sockwell, ... Cancer Research 84 (2_Supplement), B082-B082, 2024 | 1 | 2024 |
Raghu KalluriProfessor of Cancer Biology, MD Anderson Cancer CenterVerified email at mdanderson.org
