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ZA991489B - Oxaliplatin solution formulations and the method of use thereof. - Google Patents

Oxaliplatin solution formulations and the method of use thereof.

Info

Publication number
ZA991489B
ZA991489B ZA9901489A ZA991489A ZA991489B ZA 991489 B ZA991489 B ZA 991489B ZA 9901489 A ZA9901489 A ZA 9901489A ZA 991489 A ZA991489 A ZA 991489A ZA 991489 B ZA991489 B ZA 991489B
Authority
ZA
South Africa
Prior art keywords
solution formulations
oxaliplatin solution
oxaliplatin
formulations
solution
Prior art date
Application number
ZA9901489A
Other languages
English (en)
Inventor
Nicholas H Anderson
Stephen Brown
David A England
Ross Blundell
Martin R Gray
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10827600&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA991489(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ZA991489B publication Critical patent/ZA991489B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA9901489A 1998-02-25 1999-02-24 Oxaliplatin solution formulations and the method of use thereof. ZA991489B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9804013.2A GB9804013D0 (en) 1998-02-25 1998-02-25 Formulations

Publications (1)

Publication Number Publication Date
ZA991489B true ZA991489B (en) 1999-09-30

Family

ID=10827600

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9901489A ZA991489B (en) 1998-02-25 1999-02-24 Oxaliplatin solution formulations and the method of use thereof.

Country Status (27)

Country Link
US (1) US6306902B1 (xx)
EP (1) EP0943331B1 (xx)
JP (1) JP4430229B2 (xx)
KR (1) KR20010041182A (xx)
CN (1) CN1152718C (xx)
AR (1) AR015524A1 (xx)
AT (1) ATE202472T1 (xx)
AU (1) AU757101B2 (xx)
BR (1) BR9908273A (xx)
CA (1) CA2261500C (xx)
CZ (1) CZ302196B6 (xx)
DE (1) DE69900162T2 (xx)
DK (1) DK0943331T3 (xx)
ES (1) ES2161085T3 (xx)
GB (1) GB9804013D0 (xx)
GR (1) GR3036646T3 (xx)
GT (1) GT199900019A (xx)
HU (1) HU224611B1 (xx)
IL (1) IL137772A (xx)
MX (1) MXPA00008195A (xx)
NO (1) NO329900B1 (xx)
PL (1) PL197948B1 (xx)
PT (1) PT943331E (xx)
RU (1) RU2207857C2 (xx)
UA (1) UA70316C2 (xx)
WO (1) WO1999043355A2 (xx)
ZA (1) ZA991489B (xx)

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GB9804013D0 (en) 1998-02-25 1998-04-22 Sanofi Sa Formulations
DK1121117T3 (da) * 1998-10-14 2002-09-16 Debiopharm Sa Indpakning af et oxaliplatinholdigt præparat
US7070796B1 (en) 1999-08-30 2006-07-04 Debiopharm S.A. Pharmaceutically stable oxaliplatinum preparation for parenteral administration
DE60005376T2 (de) * 1999-08-30 2004-07-01 Debiopharm S.A. Oxaliplatinhaltige parenteral anzuwendende stabilisierte arzneizubereitung und verfahren zu deren herstellung
WO2002047725A2 (fr) * 2000-12-12 2002-06-20 Debiopharm S.A. Preparation pharmaceutique d'oxaliplatine pour administration par voie parenterale et procede d'obtention de ladite preparation
PT1368022E (pt) 2001-03-02 2007-10-01 Debiopharm Sa Utilização de um frasco em vidro que contém uma solução de oxaliplatina
US20040186172A1 (en) 2001-07-02 2004-09-23 Houssam Ibrahim Oxaliplatin active substance with a very low content of oxalic acid
US6476068B1 (en) * 2001-12-06 2002-11-05 Pharmacia Italia, S.P.A. Platinum derivative pharmaceutical formulations
CA2388352A1 (en) * 2002-05-31 2003-11-30 Voiceage Corporation A method and device for frequency-selective pitch enhancement of synthesized speed
DE10314377A1 (de) * 2003-03-28 2004-10-07 Stada Arzneimittel Ag Gebrauchsfertige Oxaliplatin-Lösungen
US20050020556A1 (en) * 2003-05-30 2005-01-27 Kosan Biosciences, Inc. Method for treating diseases using HSP90-inhibiting agents in combination with platinum coordination complexes
GB2441445B (en) * 2003-08-28 2008-04-23 Mayne Pharma Ltd Acid containing oxaliplatin formulation
EP2243480A1 (en) * 2003-08-28 2010-10-27 Mayne Pharma Pty Ltd Pharmaceutical formulations comprising oxaliplatin and an acid.
JP2007504177A (ja) * 2003-09-02 2007-03-01 プリヴァ−ラケマ，エー．エス． 医薬組成物、その製造方法及び治療上の使用
CZ300795B6 (cs) * 2003-09-02 2009-08-12 Pliva-Lachema A. S. Farmaceutická kompozice a zpusob její výroby
ZA200604529B (en) 2003-11-25 2007-12-27 Platco Technologies Proprietar Platinum (II) complexes, preparation and use
KR100982933B1 (ko) * 2003-12-10 2010-09-17 가부시키가이샤 도쿄다이가쿠 티엘오 디아미노시클로헥산 백금 (ⅱ) 과폴리(카르복실산)세그먼트 함유 블록 공중합체의 배위착물, 그 항종양제
CN100471493C (zh) * 2003-12-17 2009-03-25 梅比欧法姆股份有限公司 含有奥沙利铂的脂质体制剂
WO2005102312A1 (en) * 2004-04-27 2005-11-03 Mayne Pharma Limited Concentrated oxaliplatin solutions
MX2007002453A (es) 2004-09-01 2007-05-04 Platco Technologies Proprietar Preparacion de complejos de platino (ii).
US20060063720A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Oxaliplatin solution concentrate
US20060063833A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Ready-to-use oxaliplatin solutions
DE102004052877B4 (de) * 2004-11-02 2008-06-19 Ebewe Pharma Ges.M.B.H. Nfg.Kg Stabile wässrige Formulierungen eines Platin-Derivats
DE102004063764A1 (de) * 2004-12-29 2006-07-13 Hexal Ag Kunststoff-Flasche für Oxaliplatin
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
EP1879568B1 (en) * 2005-03-28 2009-05-06 Dabur Pharma Limited Stable pharmaceutical compositions of platinum (ii) antitumour agents
WO2006108428A1 (en) * 2005-04-09 2006-10-19 Vuab Pharma A.S. A process for the preparation of an oxaliplatin preparation
RU2292210C1 (ru) * 2005-05-03 2007-01-27 Институт химии и химической технологии СО РАН (ИХХТ СО РАН) Способ получения стерилизованной микрокристаллической цис-дихлородиамминплатины (ii)
DE102005038347A1 (de) * 2005-08-11 2007-02-15 Hexal Ag Herstellung einer Oxaliplatin-Lösung und Behälter sowie Behälter-Set mit der Lösung
WO2007029268A2 (en) * 2005-09-05 2007-03-15 Dabur Pharma Limited Stable oxaliplatin formulation
AU2007209099A1 (en) 2006-01-30 2007-08-02 Platco Technologies (Proprietary) Limited Preparation of platinum (ll) complexes
KR100913063B1 (ko) 2006-09-13 2009-08-21 주식회사유한양행 옥살리플라틴-함유 주사용 용액
JP2010516717A (ja) * 2007-01-22 2010-05-20 プリヴァ−ラケマ，エー．エス． アルコール性糖ベースのバッファーを有するオキサリプラチン薬学的組成物
RU2340347C2 (ru) * 2007-01-24 2008-12-10 Институт химии и химической технологии СО РАН (ИХХТ СО РАН) Способ получения стерилизованной микрокристаллической соли цис-дихлороамминизопропиламинплатины (ii)
WO2009087660A1 (en) * 2007-11-12 2009-07-16 Intas Pharmaceuticals Limited Stable oxaliplatin composition for parenteral administration
US20090130017A1 (en) * 2007-11-19 2009-05-21 Searete Llc Targeted short-lived drug delivery
US9023834B2 (en) * 2008-11-13 2015-05-05 Taigen Biotechnology Co., Ltd. Lyophilization formulation
CN101461801B (zh) * 2008-12-26 2013-05-15 辰欣药业股份有限公司 一种奥沙利铂药物组合物及其制备方法
CN102665689B (zh) 2009-09-21 2015-04-22 Jw制药公司 奥沙利铂纳米颗粒及其制备方法
CN102274171A (zh) * 2011-08-04 2011-12-14 上海希迪制药有限公司 一种奥沙利铂注射剂
CN104523674B (zh) * 2014-12-11 2017-10-24 广州市上为医药科技有限公司 一种以奥沙利铂为主药成分的注射用组合物
KR101683635B1 (ko) * 2014-12-29 2016-12-09 가천대학교 산학협력단 락테이트 금속염을 포함하는 암 치료용 약학 조성물
CN104829653B (zh) * 2015-05-06 2016-03-23 山东罗欣药业集团股份有限公司 一种奥沙利铂水合物晶体及其冻干粉针剂
SG11202006601VA (en) 2018-01-12 2020-08-28 Metimedi Pharmaceuticals Co Ltd Methods of treating chronic inflammatory diseases

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JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
PT93772A (pt) 1989-04-17 1991-01-08 Searle & Co Processo para a preparacao de composicoes para o tratamento de neoplasias, contendo um agente anti-neoplastico, por exemplo doxorubicina e um agente protector para reduzir os efeitos secundarios, por exemplo carbetimer
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JP2673331B2 (ja) * 1993-01-12 1997-11-05 田中貴金属工業 株式会社 光学的に高純度なシス―オキザラート（トランス―１―１，２―シクロヘキサンジアミン）白金（▲ｉｉ▼）
JPH06287021A (ja) * 1992-04-22 1994-10-11 Tanaka Kikinzoku Kogyo Kk 光学活性な白金錯化合物の光学的分割方法
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Also Published As

Publication number Publication date
DE69900162D1 (de) 2001-08-02
ES2161085T3 (es) 2001-11-16
EP0943331A2 (en) 1999-09-22
DK0943331T3 (da) 2001-10-15
NO20004240D0 (no) 2000-08-24
MXPA00008195A (es) 2004-11-22
DE69900162T2 (de) 2002-04-18
US6306902B1 (en) 2001-10-23
AR015524A1 (es) 2001-05-02
PL343021A1 (en) 2001-07-30
ATE202472T1 (de) 2001-07-15
UA70316C2 (uk) 2004-10-15
CZ20003089A3 (cs) 2000-12-13
CA2261500C (en) 2001-07-17
HK1036405A1 (en) 2002-01-04
GT199900019A (es) 2000-08-04
WO1999043355A2 (en) 1999-09-02
AU757101B2 (en) 2003-01-30
PL197948B1 (pl) 2008-05-30
NO329900B1 (no) 2011-01-24
PT943331E (pt) 2001-12-28
CN1152718C (zh) 2004-06-09
IL137772A (en) 2006-04-10
RU2207857C2 (ru) 2003-07-10
EP0943331A3 (en) 1999-11-03
CA2261500A1 (en) 1999-08-25
KR20010041182A (ko) 2001-05-15
JP4430229B2 (ja) 2010-03-10
GB9804013D0 (en) 1998-04-22
HUP0103707A2 (hu) 2002-02-28
CN1291886A (zh) 2001-04-18
GR3036646T3 (en) 2001-12-31
JP2002504524A (ja) 2002-02-12
HU224611B1 (hu) 2005-11-28
HUP0103707A3 (en) 2004-07-28
BR9908273A (pt) 2000-10-24
AU2632499A (en) 1999-09-15
CZ302196B6 (cs) 2010-12-15
WO1999043355A3 (en) 1999-11-04
NO20004240L (no) 2000-10-18
EP0943331B1 (en) 2001-06-27

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