ZA977326B - Tetrahydroquinoline derivatives - Google Patents

Tetrahydroquinoline derivatives

Info

Publication number: ZA977326B
Authority: ZA; South Africa
Prior art keywords: tetrahydroquinoline derivatives; tetrahydroquinoline; derivatives
Prior art date: 1996-08-17

Application number

ZA977326A

Other languages

English (en)

Inventor

Romano Di-Fabio

Alessandra Pasquarello

Fabio Maria Sabbatini

Original Assignee

Glaxo Wellcome Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-17

Filing date

1997-08-14

Publication date

1999-02-15

1997-08-14 Application filed by Glaxo Wellcome Spa filed Critical Glaxo Wellcome Spa

1999-02-15 Publication of ZA977326B publication Critical patent/ZA977326B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Quinoline Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ZA977326A 1996-08-17 1997-08-14 Tetrahydroquinoline derivatives ZA977326B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9617305.9A GB9617305D0 (en)	1996-08-17	1996-08-17	Heterocyclic compounds

Publications (1)

Publication Number	Publication Date
ZA977326B true ZA977326B (en)	1999-02-15

Family

ID=10798623

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA977326A ZA977326B (en)	1996-08-17	1997-08-14	Tetrahydroquinoline derivatives

Country Status (34)

Country	Link
US (1)	US6479488B1 (fr)
EP (1)	EP0922034B1 (fr)
JP (1)	JP4108129B2 (fr)
KR (1)	KR100552864B1 (fr)
CN (1)	CN1131214C (fr)
AP (1)	AP877A (fr)
AR (1)	AR008296A1 (fr)
AT (1)	ATE221052T1 (fr)
AU (1)	AU724473B2 (fr)
BR (1)	BR9711311B1 (fr)
CA (1)	CA2264118C (fr)
CO (1)	CO4900066A1 (fr)
CZ (1)	CZ296250B6 (fr)
DE (1)	DE69714265T2 (fr)
DK (1)	DK0922034T3 (fr)
EA (1)	EA001704B1 (fr)
ES (1)	ES2181030T3 (fr)
GB (1)	GB9617305D0 (fr)
HU (1)	HU225797B1 (fr)
ID (1)	ID18095A (fr)
IL (1)	IL128141A0 (fr)
IS (1)	IS4953A (fr)
MY (1)	MY116952A (fr)
NO (1)	NO312241B1 (fr)
NZ (1)	NZ333812A (fr)
PE (1)	PE107098A1 (fr)
PL (1)	PL194532B1 (fr)
PT (1)	PT922034E (fr)
SI (1)	SI0922034T1 (fr)
TR (1)	TR199900336T2 (fr)
TW (1)	TW449582B (fr)
WO (1)	WO1998007704A1 (fr)
YU (1)	YU6799A (fr)
ZA (1)	ZA977326B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9706294D0 (en) *	1997-03-26	1997-05-14	Glaxo Wellcome Spa	Heterocyclic compound
MY125037A (en) *	1998-06-10	2006-07-31	Glaxo Wellcome Spa	1,2,3,4 tetrahydroquinoline derivatives
US6455734B1 (en) *	2000-08-09	2002-09-24	Magnesium Diagnostics, Inc.	Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states
GB9929037D0 (en) *	1999-12-08	2000-02-02	Glaxo Wellcome Spa	Heterocyclic derivatives
DE10132725A1 (de)	2001-07-05	2006-08-03	Grünenthal GmbH	Substituierte γ-Lactonverbindungen
US7307075B2 (en) *	2001-12-28	2007-12-11	Acadia Pharmaceuticals Inc.	Tetrahydroquinoline analogues as muscarinic agonists
NZ541014A (en) *	2003-01-23	2008-05-30	Acadia Pharm Inc	Use of N-desmethylclozapine to treat schizophrenia while increasing the level of activity of a muscarinic receptor
US20050085463A1 (en) *	2003-01-23	2005-04-21	Weiner David M.	Use of N-desmethylclozapine to treat human neuropsychiatric disease
US20050250767A1 (en) *	2003-01-23	2005-11-10	Weiner David M	Use of N-desmethylclozapine to treat human neuropsychiatric disease
WO2004073639A2 (fr) *	2003-02-19	2004-09-02	Merck & Co. Inc.	Traitement de la psychose avec un activateur ectopique du recepteur m1 muscarinique
ATE426405T1 (de) *	2003-12-22	2009-04-15	Acadia Pharm Inc	Amino-substituierte diarylaa,ducyclohepten- analoga als muscarinische agonisten und verfahren zur behandlung von neuropsychiatrischen erkrankungen
CA2560671A1 (fr) *	2004-04-01	2006-01-05	Acadia Pharmaceuticals Inc.	Synthese et isolation de n-demethylclozapine et formes cristallines correspondantes
NZ565080A (en)	2005-07-22	2011-03-31	Mochida Pharm Co Ltd	Novel heterocyclidene acetamide derivative
RU2451014C2 (ru) *	2005-07-22	2012-05-20	Мотида Фармасьютикал Ко., Лтд.	Новое производное гетероциклиден ацетамида
AU2006291134C1 (en)	2005-09-12	2013-08-15	Abela Pharmaceuticals, Inc.	Systems for removing dimethyl sulfoxide (DMSO) or related compounds, or odors associated with same
WO2007033180A1 (fr)	2005-09-12	2007-03-22	Abela Pharmaceuticals, Inc.	Matieres facilitant l'administration du sulfoxyde de dimethyle (dmso) et de composes du meme type
EP2324838A1 (fr) *	2005-09-12	2011-05-25	Abela Pharmaceuticals, Inc.	Compositions comprenant du diméthylsulfoxyde
US8480797B2 (en)	2005-09-12	2013-07-09	Abela Pharmaceuticals, Inc.	Activated carbon systems for facilitating use of dimethyl sulfoxide (DMSO) by removal of same, related compounds, or associated odors
US20070105836A1 (en) *	2005-10-31	2007-05-10	Lars Pettersson	Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders
BRPI0921494A2 (pt)	2008-11-03	2018-10-30	Prad Reasearch And Development Ltd	método de planejamento de uma operação de amostragem para uma formação subterrãnea, método de contolar uma operação de amostragem de formação subterrânea, método de controlar uma operação de perfuração para uma formação subterrãnea, e método de realizar uma amostragem durante a operação de perfuração.
AU2010313253B2 (en)	2009-10-30	2015-02-19	Abela Pharmaceuticals, Inc.	Dimethyl sulfoxide (DMSO) and methylsulfonylmethane (MSM) formulations to treat osteoarthritis
EP3718547A1 (fr)	2011-10-03	2020-10-07	The University of Utah Research Foundation	Application d'antagonistes du récepteur 5-ht6 pour la réduction des déficits cognitifs du syndrome de down

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69029668T2 (de) *	1989-03-08	1997-08-07	Merck Sharp & Dohme	Tetrahydroquinolin-Derivate, verwendbar bei neurodegenerativen Krankheiten
PL186781B1 (pl) *	1995-09-29	2004-02-27	Glaxo Wellcome Spa	Nowy związek, pochodna tetrahydrochinoliny, sposób wytwarzania pochodnej tetrahydrochinoliny, środek farmaceutyczny i zastosowanie

1996
- 1996-08-17 GB GBGB9617305.9A patent/GB9617305D0/en active Pending
1997
- 1997-08-14 PL PL97331562A patent/PL194532B1/pl not_active IP Right Cessation
- 1997-08-14 SI SI9730404T patent/SI0922034T1/xx unknown
- 1997-08-14 BR BRPI9711311-5A patent/BR9711311B1/pt not_active IP Right Cessation
- 1997-08-14 AU AU45518/97A patent/AU724473B2/en not_active Ceased
- 1997-08-14 WO PCT/EP1997/004440 patent/WO1998007704A1/fr not_active Ceased
- 1997-08-14 AT AT97943809T patent/ATE221052T1/de not_active IP Right Cessation
- 1997-08-14 CZ CZ0052999A patent/CZ296250B6/cs not_active IP Right Cessation
- 1997-08-14 NZ NZ333812A patent/NZ333812A/xx active Application Revival
- 1997-08-14 CO CO97046782A patent/CO4900066A1/es unknown
- 1997-08-14 AR ARP970103703A patent/AR008296A1/es active IP Right Grant
- 1997-08-14 ID IDP972834A patent/ID18095A/id unknown
- 1997-08-14 HU HU9903108A patent/HU225797B1/hu not_active IP Right Cessation
- 1997-08-14 PT PT97943809T patent/PT922034E/pt unknown
- 1997-08-14 EP EP97943809A patent/EP0922034B1/fr not_active Expired - Lifetime
- 1997-08-14 IL IL12814197A patent/IL128141A0/xx not_active IP Right Cessation
- 1997-08-14 EA EA199900121A patent/EA001704B1/ru not_active IP Right Cessation
- 1997-08-14 JP JP51037298A patent/JP4108129B2/ja not_active Expired - Fee Related
- 1997-08-14 KR KR1019997001280A patent/KR100552864B1/ko not_active Expired - Fee Related
- 1997-08-14 DE DE69714265T patent/DE69714265T2/de not_active Expired - Lifetime
- 1997-08-14 CA CA002264118A patent/CA2264118C/fr not_active Expired - Fee Related
- 1997-08-14 DK DK97943809T patent/DK0922034T3/da active
- 1997-08-14 ES ES97943809T patent/ES2181030T3/es not_active Expired - Lifetime
- 1997-08-14 CN CN97197233A patent/CN1131214C/zh not_active Expired - Fee Related
- 1997-08-14 MY MYPI97003742A patent/MY116952A/en unknown
- 1997-08-14 AP APAP/P/1999/001459A patent/AP877A/en active
- 1997-08-14 US US09/147,568 patent/US6479488B1/en not_active Expired - Fee Related
- 1997-08-14 PE PE1997000718A patent/PE107098A1/es not_active Application Discontinuation
- 1997-08-14 ZA ZA977326A patent/ZA977326B/xx unknown
- 1997-08-14 YU YU6799A patent/YU6799A/sh unknown
- 1997-08-14 TR TR1999/00336T patent/TR199900336T2/xx unknown
- 1997-08-30 TW TW086112442A patent/TW449582B/zh not_active IP Right Cessation
1999
- 1999-01-22 IS IS4953A patent/IS4953A/is unknown
- 1999-02-16 NO NO19990723A patent/NO312241B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2264118C (fr)	2008-06-17
AR008296A1 (es)	1999-12-29
WO1998007704A1 (fr)	1998-02-26
BR9711311B1 (pt)	2009-01-13
PE107098A1 (es)	1999-01-15
DE69714265T2 (de)	2003-03-06
PL331562A1 (en)	1999-07-19
ATE221052T1 (de)	2002-08-15
ES2181030T3 (es)	2003-02-16
EA001704B1 (ru)	2001-06-25
HU225797B1 (en)	2007-09-28
DK0922034T3 (da)	2002-11-18
KR20000068172A (ko)	2000-11-25
EP0922034A1 (fr)	1999-06-16
CN1131214C (zh)	2003-12-17
DE69714265D1 (de)	2002-08-29
TW449582B (en)	2001-08-11
SI0922034T1 (en)	2003-02-28
NO312241B1 (no)	2002-04-15
AP877A (en)	2000-09-27
JP4108129B2 (ja)	2008-06-25
US6479488B1 (en)	2002-11-12
GB9617305D0 (en)	1996-09-25
BR9711311A (pt)	1999-08-17
PT922034E (pt)	2002-12-31
YU6799A (sh)	2000-03-21
AU4551897A (en)	1998-03-06
EP0922034B1 (fr)	2002-07-24
EA199900121A1 (ru)	1999-10-28
IS4953A (is)	1999-01-22
TR199900336T2 (xx)	1999-04-21
JP2001508031A (ja)	2001-06-19
CA2264118A1 (fr)	1998-02-26
KR100552864B1 (ko)	2006-02-20
PL194532B1 (pl)	2007-06-29
CN1227544A (zh)	1999-09-01
ID18095A (id)	1998-02-26
MY116952A (en)	2004-04-30
AP9901459A0 (en)	1999-03-31
NO990723D0 (no)	1999-02-16
NO990723L (no)	1999-04-14
CO4900066A1 (es)	2000-03-27
HUP9903108A3 (en)	2004-04-28
IL128141A0 (en)	1999-11-30
CZ52999A3 (cs)	1999-07-14
CZ296250B6 (cs)	2006-02-15
NZ333812A (en)	2000-07-28
AU724473B2 (en)	2000-09-21

Publication	Publication Date	Title
IL113844A0 (en)	1995-08-31	Quinoline derivatives
IL125811A0 (en)	1999-04-11	6-phenylpyridyl-2-amine derivatives
AP9701156A0 (en)	1998-01-31	6-phenylpyridyl-2-amine derivatives
IL125379A (en)	2003-05-29	19-nor-pregnene derivatives
ZA977326B (en)	1999-02-15	Tetrahydroquinoline derivatives
ZA974053B (en)	1998-11-09	Alkylaminobenzothiazole and -benzoxazole derivatives
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IL129418A0 (en)	2000-02-17	2-Methoxyphenylpiperazine derivatives
GB9404378D0 (en)	1994-04-20	Quinoline derivatives
IL125149A0 (en)	1999-01-26	Pyrazol-4-yl-hetaroyl derivatives
ZA954269B (en)	1996-05-14	Quinoline derivatives
PL334558A1 (en)	2000-03-13	Cephalosporinic derivatives
HU9701479D0 (en)	1997-10-28	N-benzylazolium derivatives
GB9402275D0 (en)	1994-03-30	Quinoline derivatives
GB9413150D0 (en)	1994-08-24	Quinoline derivatives
ZA972051B (en)	1998-09-10	Benzodiazonine derivatives
GB9603226D0 (en)	1996-04-17	Heterocyclyl-ergoline derivatives
GB9600063D0 (en)	1996-03-06	Guaridine derivatives
GB9702049D0 (en)	1997-03-19	Tetrahhydroisoquinoline derivatives
IL125974A0 (en)	1999-04-11	2-thioxotetrahydropyrimidin-4-one derivatives
IL130283A0 (en)	2000-06-01	Polysaccharide-peptide derivatives
HU9601036D0 (en)	1996-06-28	Aryl-sulfonyl-hydroxamic-acid derivatives
IL139301A0 (en)	2001-11-25	Quinoline derivatives
GB9413937D0 (en)	1994-08-31	Quinoline derivatives
GB9402306D0 (en)	1994-03-30	Quinoline derivatives