BR9711311A - Composto composi-Æo farmac-utica uso de um composto e processos para a prepara-Æo de compostos e para tratamento de um mamifero incluindo o homem - Google Patents

Composto composi-Æo farmac-utica uso de um composto e processos para a prepara-Æo de compostos e para tratamento de um mamifero incluindo o homem

Info

Publication number: BR9711311A
Authority: BR; Brazil
Prior art keywords: compound; compounds; processes; preparation; treatment
Prior art date: 1996-08-17

Application number

BR9711311A

Other languages

English (en)

Other versions

BR9711311B1 (pt

Inventor

Fabio Romano Di

Alessandra Pasquarello

Fabio Maria Sabbatini

Original Assignee

Glaxo Wellcome Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-17

Filing date

1997-08-14

Publication date

1999-08-17

1997-08-14 Application filed by Glaxo Wellcome Spa filed Critical Glaxo Wellcome Spa

1999-08-17 Publication of BR9711311A publication Critical patent/BR9711311A/pt

2009-01-13 Publication of BR9711311B1 publication Critical patent/BR9711311B1/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Quinoline Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

BRPI9711311-5A 1996-08-17 1997-08-14 derivado de 1,2,3,4-tetrahidroquinolina, composiÇço farmaceutica, uso de um derivado de 1,2,3,4-tetrahidroquinolina, e, processo para a preparaÇço de compostos. BR9711311B1 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9617305.9A GB9617305D0 (en)	1996-08-17	1996-08-17	Heterocyclic compounds
PCT/EP1997/004440 WO1998007704A1 (en)	1996-08-17	1997-08-14	Tetrahydroquinoline derivatives as eaa antagonists

Publications (2)

Publication Number	Publication Date
BR9711311A true BR9711311A (pt)	1999-08-17
BR9711311B1 BR9711311B1 (pt)	2009-01-13

Family

ID=10798623

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI9711311-5A BR9711311B1 (pt)	1996-08-17	1997-08-14	derivado de 1,2,3,4-tetrahidroquinolina, composiÇço farmaceutica, uso de um derivado de 1,2,3,4-tetrahidroquinolina, e, processo para a preparaÇço de compostos.

Country Status (34)

Country	Link
US (1)	US6479488B1 (pt)
EP (1)	EP0922034B1 (pt)
JP (1)	JP4108129B2 (pt)
KR (1)	KR100552864B1 (pt)
CN (1)	CN1131214C (pt)
AP (1)	AP877A (pt)
AR (1)	AR008296A1 (pt)
AT (1)	ATE221052T1 (pt)
AU (1)	AU724473B2 (pt)
BR (1)	BR9711311B1 (pt)
CA (1)	CA2264118C (pt)
CO (1)	CO4900066A1 (pt)
CZ (1)	CZ296250B6 (pt)
DE (1)	DE69714265T2 (pt)
DK (1)	DK0922034T3 (pt)
EA (1)	EA001704B1 (pt)
ES (1)	ES2181030T3 (pt)
GB (1)	GB9617305D0 (pt)
HU (1)	HU225797B1 (pt)
ID (1)	ID18095A (pt)
IL (1)	IL128141A0 (pt)
IS (1)	IS4953A (pt)
MY (1)	MY116952A (pt)
NO (1)	NO312241B1 (pt)
NZ (1)	NZ333812A (pt)
PE (1)	PE107098A1 (pt)
PL (1)	PL194532B1 (pt)
PT (1)	PT922034E (pt)
SI (1)	SI0922034T1 (pt)
TR (1)	TR199900336T2 (pt)
TW (1)	TW449582B (pt)
WO (1)	WO1998007704A1 (pt)
YU (1)	YU6799A (pt)
ZA (1)	ZA977326B (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9706294D0 (en) *	1997-03-26	1997-05-14	Glaxo Wellcome Spa	Heterocyclic compound
MY125037A (en) *	1998-06-10	2006-07-31	Glaxo Wellcome Spa	1,2,3,4 tetrahydroquinoline derivatives
US6455734B1 (en)	2000-08-09	2002-09-24	Magnesium Diagnostics, Inc.	Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states
GB9929037D0 (en) *	1999-12-08	2000-02-02	Glaxo Wellcome Spa	Heterocyclic derivatives
DE10132725A1 (de)	2001-07-05	2006-08-03	Grünenthal GmbH	Substituierte γ-Lactonverbindungen
WO2003057672A2 (en) *	2001-12-28	2003-07-17	Acadia Pharmaceuticals, Inc.	Tetrahydroquinoline analogues as muscarinic agonists
EP1589974A2 (en) *	2003-01-23	2005-11-02	Acadia Pharmaceuticals Inc.	Use of n-desmethylclozapine to treat human neuropsychiatric disease
US20050250767A1 (en) *	2003-01-23	2005-11-10	Weiner David M	Use of N-desmethylclozapine to treat human neuropsychiatric disease
US20050085463A1 (en) *	2003-01-23	2005-04-21	Weiner David M.	Use of N-desmethylclozapine to treat human neuropsychiatric disease
EP1596867A4 (en) *	2003-02-19	2006-03-22	Merck & Co Inc	TREATMENT OF PSYCHOSIS WITH A MUSCARIN M1 RECEPTOR ECTOPIC ACTIVATOR
PL1696931T3 (pl) *	2003-12-22	2009-10-30	Acadia Pharm Inc	Aminopodstawione analogi diarylo[A,D]cykloheptenowe jako agoniści receptorów muskarynowych i sposoby leczenia chorób neuropsychiatrycznych
RU2006138497A (ru) *	2004-04-01	2008-05-10	Акадиа Фармасьютикалз Инк. (Us)	Кристаллические формы n-десметилклозапина
RU2451014C2 (ru) *	2005-07-22	2012-05-20	Мотида Фармасьютикал Ко., Лтд.	Новое производное гетероциклиден ацетамида
CA2616079C (en) *	2005-07-22	2012-09-25	Mochida Pharmaceutical Co., Ltd.	Novel heterocyclidene acetamide derivative
WO2007033180A1 (en)	2005-09-12	2007-03-22	Abela Pharmaceuticals, Inc.	Materials for facilitating administration of dimethyl sulfoxide (dmso) and related compounds
US8480797B2 (en)	2005-09-12	2013-07-09	Abela Pharmaceuticals, Inc.	Activated carbon systems for facilitating use of dimethyl sulfoxide (DMSO) by removal of same, related compounds, or associated odors
US9427419B2 (en)	2005-09-12	2016-08-30	Abela Pharmaceuticals, Inc.	Compositions comprising dimethyl sulfoxide (DMSO)
CA2622204C (en)	2005-09-12	2016-10-11	Abela Pharmaceuticals, Inc.	Systems for removing dimethyl sulfoxide (dmso) or related compounds, or odors associated with same
US20070105836A1 (en) *	2005-10-31	2007-05-10	Lars Pettersson	Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders
BRPI0921494A2 (pt)	2008-11-03	2018-10-30	Prad Reasearch And Development Ltd	método de planejamento de uma operação de amostragem para uma formação subterrãnea, método de contolar uma operação de amostragem de formação subterrânea, método de controlar uma operação de perfuração para uma formação subterrãnea, e método de realizar uma amostragem durante a operação de perfuração.
AU2010313253B2 (en)	2009-10-30	2015-02-19	Abela Pharmaceuticals, Inc.	Dimethyl sulfoxide (DMSO) and methylsulfonylmethane (MSM) formulations to treat osteoarthritis
EP2763676B1 (en)	2011-10-03	2019-12-25	The University of Utah Research Foundation	Application of 5-ht6 receptor antagonists for the alleviation of cognitive deficits of down syndrome

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69029668T2 (de)	1989-03-08	1997-08-07	Merck Sharp & Dohme	Tetrahydroquinolin-Derivate, verwendbar bei neurodegenerativen Krankheiten
CZ292379B6 (cs) *	1995-09-29	2003-09-17	Glaxo Wellcome Spa	Tetrahydrochinolinové deriváty, způsob jejich výroby a farmaceutický prostředek s jejich obsahem

1996
- 1996-08-17 GB GBGB9617305.9A patent/GB9617305D0/en active Pending
1997
- 1997-08-14 PE PE1997000718A patent/PE107098A1/es not_active Application Discontinuation
- 1997-08-14 AP APAP/P/1999/001459A patent/AP877A/en active
- 1997-08-14 AT AT97943809T patent/ATE221052T1/de not_active IP Right Cessation
- 1997-08-14 CN CN97197233A patent/CN1131214C/zh not_active Expired - Fee Related
- 1997-08-14 AU AU45518/97A patent/AU724473B2/en not_active Ceased
- 1997-08-14 JP JP51037298A patent/JP4108129B2/ja not_active Expired - Fee Related
- 1997-08-14 EP EP97943809A patent/EP0922034B1/en not_active Expired - Lifetime
- 1997-08-14 WO PCT/EP1997/004440 patent/WO1998007704A1/en not_active Ceased
- 1997-08-14 SI SI9730404T patent/SI0922034T1/xx unknown
- 1997-08-14 MY MYPI97003742A patent/MY116952A/en unknown
- 1997-08-14 DK DK97943809T patent/DK0922034T3/da active
- 1997-08-14 EA EA199900121A patent/EA001704B1/ru not_active IP Right Cessation
- 1997-08-14 PT PT97943809T patent/PT922034E/pt unknown
- 1997-08-14 HU HU9903108A patent/HU225797B1/hu not_active IP Right Cessation
- 1997-08-14 US US09/147,568 patent/US6479488B1/en not_active Expired - Fee Related
- 1997-08-14 ZA ZA977326A patent/ZA977326B/xx unknown
- 1997-08-14 ES ES97943809T patent/ES2181030T3/es not_active Expired - Lifetime
- 1997-08-14 AR ARP970103703A patent/AR008296A1/es active IP Right Grant
- 1997-08-14 CO CO97046782A patent/CO4900066A1/es unknown
- 1997-08-14 CA CA002264118A patent/CA2264118C/en not_active Expired - Fee Related
- 1997-08-14 YU YU6799A patent/YU6799A/sh unknown
- 1997-08-14 TR TR1999/00336T patent/TR199900336T2/xx unknown
- 1997-08-14 KR KR1019997001280A patent/KR100552864B1/ko not_active Expired - Fee Related
- 1997-08-14 DE DE69714265T patent/DE69714265T2/de not_active Expired - Lifetime
- 1997-08-14 NZ NZ333812A patent/NZ333812A/xx active Application Revival
- 1997-08-14 PL PL97331562A patent/PL194532B1/pl not_active IP Right Cessation
- 1997-08-14 BR BRPI9711311-5A patent/BR9711311B1/pt not_active IP Right Cessation
- 1997-08-14 CZ CZ0052999A patent/CZ296250B6/cs not_active IP Right Cessation
- 1997-08-14 ID IDP972834A patent/ID18095A/id unknown
- 1997-08-14 IL IL12814197A patent/IL128141A0/xx not_active IP Right Cessation
- 1997-08-30 TW TW086112442A patent/TW449582B/zh not_active IP Right Cessation
1999
- 1999-01-22 IS IS4953A patent/IS4953A/is unknown
- 1999-02-16 NO NO19990723A patent/NO312241B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
IS4953A (is)	1999-01-22
ID18095A (id)	1998-02-26
YU6799A (sh)	2000-03-21
CN1131214C (zh)	2003-12-17
DE69714265D1 (de)	2002-08-29
SI0922034T1 (en)	2003-02-28
PL331562A1 (en)	1999-07-19
CZ52999A3 (cs)	1999-07-14
HUP9903108A3 (en)	2004-04-28
CZ296250B6 (cs)	2006-02-15
AP877A (en)	2000-09-27
NO990723D0 (no)	1999-02-16
KR20000068172A (ko)	2000-11-25
NO312241B1 (no)	2002-04-15
AU4551897A (en)	1998-03-06
MY116952A (en)	2004-04-30
CN1227544A (zh)	1999-09-01
DE69714265T2 (de)	2003-03-06
JP2001508031A (ja)	2001-06-19
BR9711311B1 (pt)	2009-01-13
CA2264118C (en)	2008-06-17
EA001704B1 (ru)	2001-06-25
EP0922034B1 (en)	2002-07-24
TW449582B (en)	2001-08-11
KR100552864B1 (ko)	2006-02-20
EP0922034A1 (en)	1999-06-16
DK0922034T3 (da)	2002-11-18
AP9901459A0 (en)	1999-03-31
US6479488B1 (en)	2002-11-12
PL194532B1 (pl)	2007-06-29
EA199900121A1 (ru)	1999-10-28
NZ333812A (en)	2000-07-28
IL128141A0 (en)	1999-11-30
CA2264118A1 (en)	1998-02-26
GB9617305D0 (en)	1996-09-25
PT922034E (pt)	2002-12-31
CO4900066A1 (es)	2000-03-27
HU225797B1 (en)	2007-09-28
ZA977326B (en)	1999-02-15
ATE221052T1 (de)	2002-08-15
PE107098A1 (es)	1999-01-15
ES2181030T3 (es)	2003-02-16
NO990723L (no)	1999-04-14
TR199900336T2 (xx)	1999-04-21
WO1998007704A1 (en)	1998-02-26
AR008296A1 (es)	1999-12-29
JP4108129B2 (ja)	2008-06-25
AU724473B2 (en)	2000-09-21

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Legal Events

Date	Code	Title	Description
2006-12-05	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2007-06-19	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2008-01-02	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2008-01-02	B15K	Others concerning applications: alteration of classification	Free format text: ALTERADA DE INT.CL: C07D 215/48, A61K 31/47, A61P 25/28, A61P 43/00 Ipc: C07D 215/48 (2007.10), A61K 31/47 (2007.10), A61P
2008-08-26	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2009-01-13	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 13/01/2009, OBSERVADAS AS CONDICOES LEGAIS.
2013-02-13	B24C	Patent annual fee: request for for restoration	Free format text: REFERENTE AS 14A E 15A ANUIDADES.
2013-09-24	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2197 DE 13/02/2013 E AO NAO RECOLHIMENTO DA 16A ANUIDADE.