ZA958257B - Liposomes with enhanced entrapment capacity method and use - Google Patents
Liposomes with enhanced entrapment capacity method and useInfo
- Publication number
- ZA958257B ZA958257B ZA958257A ZA958257A ZA958257B ZA 958257 B ZA958257 B ZA 958257B ZA 958257 A ZA958257 A ZA 958257A ZA 958257 A ZA958257 A ZA 958257A ZA 958257 B ZA958257 B ZA 958257B
- Authority
- ZA
- South Africa
- Prior art keywords
- liposome vesicles
- precursor
- carrier phase
- liposomes
- expanded
- Prior art date
Links
- 239000002502 liposome Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 4
- 239000002243 precursor Substances 0.000 abstract 2
- 239000008365 aqueous carrier Substances 0.000 abstract 1
- 230000008021 deposition Effects 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000012856 packing Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP94810570 | 1994-09-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA958257B true ZA958257B (en) | 1996-05-31 |
Family
ID=8218319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA958257A ZA958257B (en) | 1994-09-30 | 1995-09-29 | Liposomes with enhanced entrapment capacity method and use |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US5702722A (xx) |
| EP (1) | EP0731690B1 (xx) |
| JP (2) | JPH09505773A (xx) |
| KR (1) | KR100452306B1 (xx) |
| CN (1) | CN1098067C (xx) |
| AT (1) | ATE242627T1 (xx) |
| AU (1) | AU699791B2 (xx) |
| CA (1) | CA2175050C (xx) |
| CZ (1) | CZ147096A3 (xx) |
| DE (1) | DE69531041T2 (xx) |
| ES (1) | ES2201115T3 (xx) |
| FI (1) | FI962255A0 (xx) |
| IL (1) | IL115468A (xx) |
| NO (1) | NO317053B1 (xx) |
| NZ (1) | NZ292260A (xx) |
| WO (1) | WO1996010393A1 (xx) |
| ZA (1) | ZA958257B (xx) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6698196A (en) | 1995-08-15 | 1997-03-12 | Universite Libre De Bruxelles | Liposomes preparation method and plant |
| ES2373861T3 (es) | 1997-09-18 | 2012-02-09 | Pacira Pharmaceuticals, Inc. | Composiciones anestésicas liposomiales de liberación sostenida. |
| ATE554748T1 (de) * | 1997-11-14 | 2012-05-15 | Pacira Pharmaceuticals Inc | Herstellung von multivesikulären liposomen |
| IL140899A0 (en) | 1998-07-17 | 2002-02-10 | Skyepharma Inc | Lipid/polymer containing pharmaceutical compositions and processes for the preparation thereof |
| US20030124180A1 (en) * | 2000-05-02 | 2003-07-03 | Jurgen Ebert | Liposomes containing active substances |
| AU2001266696A1 (en) | 2000-06-02 | 2001-12-11 | Bracco Research Usa | Compounds for targeting endothelial cells |
| JP2004532252A (ja) * | 2001-05-31 | 2004-10-21 | スカイファーマ インコーポレーテッド | リポソームおよびミクロスフェア中のナノ懸濁物のカプセル化 |
| US20040082521A1 (en) * | 2002-03-29 | 2004-04-29 | Azaya Therapeutics Inc. | Novel formulations of digitalis glycosides for treating cell-proliferative and other diseases |
| AU2003287526A1 (en) * | 2002-11-06 | 2004-06-03 | Protein-stabilized liposomal formulations of pharmaceutical agents | |
| CN100427064C (zh) * | 2003-04-16 | 2008-10-22 | 沈阳药科大学 | 一种制备脂质体的新方法 |
| US8012457B2 (en) | 2004-06-04 | 2011-09-06 | Acusphere, Inc. | Ultrasound contrast agent dosage formulation |
| JP2009513621A (ja) * | 2005-10-26 | 2009-04-02 | イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム | リポソームを調製する方法及びその使用 |
| CN101017164B (zh) * | 2006-07-21 | 2011-08-31 | 上海中医药大学 | 脂质体药物包封率测定方法 |
| JP5126874B2 (ja) * | 2007-05-21 | 2013-01-23 | 国立大学法人神戸大学 | リポソーム製剤の製造方法 |
| US9445975B2 (en) * | 2008-10-03 | 2016-09-20 | Access Business Group International, Llc | Composition and method for preparing stable unilamellar liposomal suspension |
| JPWO2010041727A1 (ja) * | 2008-10-10 | 2012-03-08 | 株式会社リポソーム工学研究所 | リポソーム製造装置 |
| JPWO2010044399A1 (ja) * | 2008-10-14 | 2012-03-15 | 株式会社リポソーム工学研究所 | 多機能リポソーム自動製造装置 |
| FR2947172B1 (fr) * | 2009-06-29 | 2011-09-09 | Natura Cosmeticos Sa | Composition cosmetique, kit de traitement de la peau, procede pour traiter les peaux grasses, mixtes ou acneiques |
| JP5669058B2 (ja) * | 2010-05-10 | 2015-02-12 | 独立行政法人科学技術振興機構 | リポソームの製造方法 |
| WO2012136813A2 (en) | 2011-04-07 | 2012-10-11 | Universitetet I Oslo | Agents for medical radar diagnosis |
| WO2012157721A1 (ja) * | 2011-05-17 | 2012-11-22 | 三菱瓦斯化学株式会社 | ピロロキノリンキノンと糖を含むリポソーム |
| GB201116248D0 (en) * | 2011-09-20 | 2011-11-02 | Glaxosmithkline Biolog Sa | Liposome production using isopropanol |
| JP2015209462A (ja) * | 2014-04-25 | 2015-11-24 | 株式会社島津製作所 | 両親媒性ブロックポリマー分子集合体の作製法 |
| JP6373749B2 (ja) * | 2014-12-19 | 2018-08-15 | 富士フイルム株式会社 | リポソームの製造方法及びリポソーム製造装置 |
| JP6316182B2 (ja) | 2014-12-19 | 2018-04-25 | 富士フイルム株式会社 | リポソームの製造方法及びリポソーム製造装置 |
| US10486041B2 (en) | 2015-10-07 | 2019-11-26 | Easton Diamond Sports, Llc | Ball bat with adjustable-weight end cap |
| WO2019191731A1 (en) * | 2018-03-30 | 2019-10-03 | Tlc Biopharmaceuticals, Inc. | Sustained-release anesthetic compositions and methods of preparation thereof |
| CN109966249B (zh) * | 2019-03-11 | 2021-06-22 | 塔尔普(北京)制药技术有限公司 | 一种超临界流化床制备脂质体的装置 |
| US11224788B2 (en) | 2019-10-29 | 2022-01-18 | Easton Diamond Sports, Llc | Vibration-damping end caps for ball bats |
| CN112915065B (zh) * | 2020-12-09 | 2022-04-08 | 中国农业科学院都市农业研究所 | 一种紫杉醇药物递送载体及其制备方法 |
| US11278494B1 (en) | 2021-01-22 | 2022-03-22 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12151024B2 (en) | 2021-01-22 | 2024-11-26 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US11357727B1 (en) | 2021-01-22 | 2022-06-14 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US11033495B1 (en) | 2021-01-22 | 2021-06-15 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| CN117979970A (zh) | 2021-10-14 | 2024-05-03 | 帕西拉制药有限公司 | 布比卡因多囊脂质体制剂及其用途 |
| WO2025021946A1 (en) | 2023-07-25 | 2025-01-30 | Quantoom Biosciences S.A. | Method and system for the production of a carrier |
| US12251472B1 (en) | 2024-05-20 | 2025-03-18 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12246092B1 (en) | 2024-05-20 | 2025-03-11 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12251468B1 (en) | 2024-05-20 | 2025-03-18 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE186352C (xx) * | ||||
| US4162282A (en) * | 1976-04-22 | 1979-07-24 | Coulter Electronics, Inc. | Method for producing uniform particles |
| FR2521565B1 (fr) * | 1982-02-17 | 1985-07-05 | Dior Sa Parfums Christian | Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees |
| US4485054A (en) * | 1982-10-04 | 1984-11-27 | Lipoderm Pharmaceuticals Limited | Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV) |
| GB2134869A (en) * | 1983-02-15 | 1984-08-22 | Squibb & Sons Inc | Method of preparing liposomes and products produced thereby |
| GB2135647A (en) * | 1983-02-15 | 1984-09-05 | Squibb & Sons Inc | Method of preparing liposomes and products produced thereby |
| US4622188A (en) * | 1984-12-21 | 1986-11-11 | E. I. Du Pont De Nemours And Company | Method for manufacturing liposomes |
| US4619795A (en) * | 1984-12-24 | 1986-10-28 | Technicon Instruments Corp. | Method for preparing lipid vesicles |
| JP3399009B2 (ja) * | 1993-02-25 | 2003-04-21 | 日本油脂株式会社 | リポソームの製造方法 |
-
1995
- 1995-09-12 US US08/527,087 patent/US5702722A/en not_active Expired - Lifetime
- 1995-09-28 DE DE69531041T patent/DE69531041T2/de not_active Expired - Lifetime
- 1995-09-28 AU AU33987/95A patent/AU699791B2/en not_active Ceased
- 1995-09-28 AT AT95930698T patent/ATE242627T1/de not_active IP Right Cessation
- 1995-09-28 EP EP95930698A patent/EP0731690B1/en not_active Expired - Lifetime
- 1995-09-28 NZ NZ292260A patent/NZ292260A/en unknown
- 1995-09-28 JP JP8511564A patent/JPH09505773A/ja active Pending
- 1995-09-28 KR KR1019960702815A patent/KR100452306B1/ko not_active Expired - Fee Related
- 1995-09-28 ES ES95930698T patent/ES2201115T3/es not_active Expired - Lifetime
- 1995-09-28 CZ CZ961470A patent/CZ147096A3/cs unknown
- 1995-09-28 CN CN95190971A patent/CN1098067C/zh not_active Expired - Fee Related
- 1995-09-28 WO PCT/IB1995/000802 patent/WO1996010393A1/en not_active Ceased
- 1995-09-28 CA CA002175050A patent/CA2175050C/en not_active Expired - Fee Related
- 1995-09-29 IL IL11546895A patent/IL115468A/xx not_active IP Right Cessation
- 1995-09-29 ZA ZA958257A patent/ZA958257B/xx unknown
-
1996
- 1996-05-29 NO NO19962189A patent/NO317053B1/no not_active IP Right Cessation
- 1996-05-29 FI FI962255A patent/FI962255A0/fi not_active IP Right Cessation
-
1997
- 1997-08-12 US US08/909,097 patent/US5895661A/en not_active Expired - Lifetime
- 1997-08-12 US US08/909,827 patent/US5980937A/en not_active Expired - Lifetime
-
2008
- 2008-09-04 JP JP2008227239A patent/JP2009046491A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0731690A1 (en) | 1996-09-18 |
| KR100452306B1 (ko) | 2004-12-23 |
| FI962255A7 (fi) | 1996-05-29 |
| CA2175050A1 (en) | 1996-04-11 |
| US5980937A (en) | 1999-11-09 |
| CN1136273A (zh) | 1996-11-20 |
| IL115468A (en) | 2000-08-13 |
| DE69531041D1 (de) | 2003-07-17 |
| CA2175050C (en) | 2005-06-14 |
| NZ292260A (en) | 1997-05-26 |
| ES2201115T3 (es) | 2004-03-16 |
| JPH09505773A (ja) | 1997-06-10 |
| AU3398795A (en) | 1996-04-26 |
| DE69531041T2 (de) | 2004-03-04 |
| ATE242627T1 (de) | 2003-06-15 |
| CN1098067C (zh) | 2003-01-08 |
| NO962189L (no) | 1996-07-23 |
| CZ147096A3 (en) | 1996-08-14 |
| WO1996010393A1 (en) | 1996-04-11 |
| EP0731690B1 (en) | 2003-06-11 |
| FI962255A0 (fi) | 1996-05-29 |
| KR960706328A (ko) | 1996-12-09 |
| US5702722A (en) | 1997-12-30 |
| IL115468A0 (en) | 1995-12-31 |
| JP2009046491A (ja) | 2009-03-05 |
| NO962189D0 (no) | 1996-05-29 |
| AU699791B2 (en) | 1998-12-17 |
| NO317053B1 (no) | 2004-08-02 |
| US5895661A (en) | 1999-04-20 |
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