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DE69531041D1 - Liposomen mit erhöhtem einschlussvermögen, deren herstellung und verwendung - Google Patents

Liposomen mit erhöhtem einschlussvermögen, deren herstellung und verwendung

Info

Publication number
DE69531041D1
DE69531041D1 DE69531041T DE69531041T DE69531041D1 DE 69531041 D1 DE69531041 D1 DE 69531041D1 DE 69531041 T DE69531041 T DE 69531041T DE 69531041 T DE69531041 T DE 69531041T DE 69531041 D1 DE69531041 D1 DE 69531041D1
Authority
DE
Germany
Prior art keywords
liposome vesicles
precursor
carrier phase
liposomes
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69531041T
Other languages
English (en)
Other versions
DE69531041T2 (de
Inventor
Herve Tournier
Michel Schneider
Christian Guillot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco Research SA
Original Assignee
Bracco Research SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8218319&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69531041(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bracco Research SA filed Critical Bracco Research SA
Publication of DE69531041D1 publication Critical patent/DE69531041D1/de
Application granted granted Critical
Publication of DE69531041T2 publication Critical patent/DE69531041T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69531041T 1994-09-30 1995-09-28 Liposomen mit erhöhtem einschlussvermögen, deren herstellung und verwendung Expired - Lifetime DE69531041T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT9481057 1994-09-30
EP94810570 1994-09-30
PCT/IB1995/000802 WO1996010393A1 (en) 1994-09-30 1995-09-28 Liposomes with enhanced entrapment capacity, method and use

Publications (2)

Publication Number Publication Date
DE69531041D1 true DE69531041D1 (de) 2003-07-17
DE69531041T2 DE69531041T2 (de) 2004-03-04

Family

ID=8218319

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69531041T Expired - Lifetime DE69531041T2 (de) 1994-09-30 1995-09-28 Liposomen mit erhöhtem einschlussvermögen, deren herstellung und verwendung

Country Status (17)

Country Link
US (3) US5702722A (de)
EP (1) EP0731690B1 (de)
JP (2) JPH09505773A (de)
KR (1) KR100452306B1 (de)
CN (1) CN1098067C (de)
AT (1) ATE242627T1 (de)
AU (1) AU699791B2 (de)
CA (1) CA2175050C (de)
CZ (1) CZ147096A3 (de)
DE (1) DE69531041T2 (de)
ES (1) ES2201115T3 (de)
FI (1) FI962255A7 (de)
IL (1) IL115468A (de)
NO (1) NO317053B1 (de)
NZ (1) NZ292260A (de)
WO (1) WO1996010393A1 (de)
ZA (1) ZA958257B (de)

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EP0853473A1 (de) * 1995-08-15 1998-07-22 Universite Libre De Bruxelles Verfahren und anlage zur herstellung von liposomen
EP2198854B1 (de) 1997-09-18 2011-11-30 Pacira Pharmaceuticals, Inc. Retardierte Freisetzung Liposomaler Anesthetischer Zusammensetzungen
ES2384094T3 (es) 1997-11-14 2012-06-29 Pacira Pharmaceuticals, Inc. Producción de liposomas multivesiculares
ATE428371T1 (de) 1998-07-17 2009-05-15 Pacira Pharmaceuticals Inc Biologisch abbaubare anordnungen zur kontrollierten freigabe eingeschlossener substanzen
US20030124180A1 (en) * 2000-05-02 2003-07-03 Jurgen Ebert Liposomes containing active substances
EP1289565B1 (de) 2000-06-02 2015-04-22 Bracco Suisse SA Arzneimitteln zur zielgerichtung von endothelzellen
NZ529544A (en) * 2001-05-31 2006-11-30 Skyepharma Inc Encapsulation of nanosuspensions in liposomes and microspheres
US20040082521A1 (en) * 2002-03-29 2004-04-29 Azaya Therapeutics Inc. Novel formulations of digitalis glycosides for treating cell-proliferative and other diseases
EP1585504A4 (de) * 2002-11-06 2009-07-15 Azaya Therapeutics Inc Proteinstabilisierte liposomale formulierungen pharmazeutischer wirkstoffe
CN100427064C (zh) * 2003-04-16 2008-10-22 沈阳药科大学 一种制备脂质体的新方法
US8012457B2 (en) 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
JP2009513621A (ja) * 2005-10-26 2009-04-02 イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム リポソームを調製する方法及びその使用
CN101017164B (zh) * 2006-07-21 2011-08-31 上海中医药大学 脂质体药物包封率测定方法
JP5126874B2 (ja) * 2007-05-21 2013-01-23 国立大学法人神戸大学 リポソーム製剤の製造方法
US9445975B2 (en) * 2008-10-03 2016-09-20 Access Business Group International, Llc Composition and method for preparing stable unilamellar liposomal suspension
US20110221082A1 (en) * 2008-10-10 2011-09-15 Hashimoto Electronic Industry Co., Ltd. Liposome manufacturing device
WO2010044399A1 (ja) * 2008-10-14 2010-04-22 株式会社リポソーム工学研究所 多機能リポソーム自動製造装置
FR2947172B1 (fr) * 2009-06-29 2011-09-09 Natura Cosmeticos Sa Composition cosmetique, kit de traitement de la peau, procede pour traiter les peaux grasses, mixtes ou acneiques
JP5669058B2 (ja) * 2010-05-10 2015-02-12 独立行政法人科学技術振興機構 リポソームの製造方法
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
JP5929907B2 (ja) * 2011-05-17 2016-06-08 三菱瓦斯化学株式会社 ピロロキノリンキノンと糖を含むリポソーム
GB201116248D0 (en) * 2011-09-20 2011-11-02 Glaxosmithkline Biolog Sa Liposome production using isopropanol
JP2015209462A (ja) * 2014-04-25 2015-11-24 株式会社島津製作所 両親媒性ブロックポリマー分子集合体の作製法
JP6316182B2 (ja) 2014-12-19 2018-04-25 富士フイルム株式会社 リポソームの製造方法及びリポソーム製造装置
JP6373749B2 (ja) * 2014-12-19 2018-08-15 富士フイルム株式会社 リポソームの製造方法及びリポソーム製造装置
US10486041B2 (en) 2015-10-07 2019-11-26 Easton Diamond Sports, Llc Ball bat with adjustable-weight end cap
WO2019191731A1 (en) * 2018-03-30 2019-10-03 Tlc Biopharmaceuticals, Inc. Sustained-release anesthetic compositions and methods of preparation thereof
CN109966249B (zh) * 2019-03-11 2021-06-22 塔尔普(北京)制药技术有限公司 一种超临界流化床制备脂质体的装置
US11224788B2 (en) 2019-10-29 2022-01-18 Easton Diamond Sports, Llc Vibration-damping end caps for ball bats
CN112915065B (zh) * 2020-12-09 2022-04-08 中国农业科学院都市农业研究所 一种紫杉醇药物递送载体及其制备方法
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12151024B2 (en) 2021-01-22 2024-11-26 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
WO2023064464A1 (en) 2021-10-14 2023-04-20 Pacira Pharmaceuticals, Inc. Bupivacaine multivesicular liposome formulations and uses thereof
WO2025021946A1 (en) 2023-07-25 2025-01-30 Quantoom Biosciences S.A. Method and system for the production of a carrier
US12156940B1 (en) 2024-05-20 2024-12-03 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12280149B1 (en) 2024-05-20 2025-04-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12251472B1 (en) 2024-05-20 2025-03-18 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE186352C (de) *
US4162282A (en) * 1976-04-22 1979-07-24 Coulter Electronics, Inc. Method for producing uniform particles
FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
US4485054A (en) * 1982-10-04 1984-11-27 Lipoderm Pharmaceuticals Limited Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV)
GB2135647A (en) * 1983-02-15 1984-09-05 Squibb & Sons Inc Method of preparing liposomes and products produced thereby
GB2134869A (en) * 1983-02-15 1984-08-22 Squibb & Sons Inc Method of preparing liposomes and products produced thereby
US4622188A (en) * 1984-12-21 1986-11-11 E. I. Du Pont De Nemours And Company Method for manufacturing liposomes
US4619795A (en) * 1984-12-24 1986-10-28 Technicon Instruments Corp. Method for preparing lipid vesicles
JP3399009B2 (ja) * 1993-02-25 2003-04-21 日本油脂株式会社 リポソームの製造方法

Also Published As

Publication number Publication date
KR100452306B1 (ko) 2004-12-23
US5702722A (en) 1997-12-30
NO962189L (no) 1996-07-23
FI962255A0 (fi) 1996-05-29
ZA958257B (en) 1996-05-31
NZ292260A (en) 1997-05-26
EP0731690A1 (de) 1996-09-18
CN1136273A (zh) 1996-11-20
US5980937A (en) 1999-11-09
CN1098067C (zh) 2003-01-08
CZ147096A3 (en) 1996-08-14
AU3398795A (en) 1996-04-26
DE69531041T2 (de) 2004-03-04
ES2201115T3 (es) 2004-03-16
FI962255A7 (fi) 1996-05-29
AU699791B2 (en) 1998-12-17
IL115468A0 (en) 1995-12-31
CA2175050C (en) 2005-06-14
NO317053B1 (no) 2004-08-02
EP0731690B1 (de) 2003-06-11
ATE242627T1 (de) 2003-06-15
CA2175050A1 (en) 1996-04-11
IL115468A (en) 2000-08-13
US5895661A (en) 1999-04-20
NO962189D0 (no) 1996-05-29
WO1996010393A1 (en) 1996-04-11
JP2009046491A (ja) 2009-03-05
JPH09505773A (ja) 1997-06-10
KR960706328A (ko) 1996-12-09

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