ZA88309B - 3(2h)pyridazinone,process for its preparation and antagonistic agent against srs-a containing it - Google Patents
3(2h)pyridazinone,process for its preparation and antagonistic agent against srs-a containing itInfo
- Publication number
- ZA88309B ZA88309B ZA880309A ZA88309A ZA88309B ZA 88309 B ZA88309 B ZA 88309B ZA 880309 A ZA880309 A ZA 880309A ZA 88309 A ZA88309 A ZA 88309A ZA 88309 B ZA88309 B ZA 88309B
- Authority
- ZA
- South Africa
- Prior art keywords
- hydrogen
- alkyl
- branched
- straight chained
- pyridazinone
- Prior art date
Links
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical compound OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 title abstract 2
- 230000003042 antagnostic effect Effects 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 11
- 239000001257 hydrogen Substances 0.000 abstract 11
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 10
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 6
- 229910052736 halogen Chemical group 0.000 abstract 3
- 150000002367 halogens Chemical group 0.000 abstract 3
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Chemical group 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1023187 | 1987-01-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA88309B true ZA88309B (en) | 1988-07-01 |
Family
ID=11744513
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA880309A ZA88309B (en) | 1987-01-20 | 1988-01-18 | 3(2h)pyridazinone,process for its preparation and antagonistic agent against srs-a containing it |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4978665A (xx) |
| EP (1) | EP0275997B1 (xx) |
| AT (1) | ATE83773T1 (xx) |
| AU (1) | AU597141B2 (xx) |
| CA (1) | CA1324792C (xx) |
| DD (1) | DD287497A5 (xx) |
| DE (2) | DE3876813D1 (xx) |
| HU (1) | HU198696B (xx) |
| SU (1) | SU1584750A3 (xx) |
| ZA (1) | ZA88309B (xx) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0186817B1 (en) * | 1984-12-10 | 1989-08-02 | Nissan Chemical Industries Ltd. | 3(2h)pyridazinone, process for its preparation and anti-allergic agent containing it |
| IE62890B1 (en) * | 1988-12-06 | 1995-03-08 | Hafslund Nycomed Pharma | New piperazinylalkyl-3(2h)-pyridazinones process for the preparation thereof and the use thereof as agents lowering blood pressure |
| JPH02256668A (ja) * | 1988-12-20 | 1990-10-17 | Nissan Chem Ind Ltd | ピリダジノン誘導体 |
| DE4009761A1 (de) * | 1989-07-28 | 1991-01-31 | Bayer Ag | 2h-pyridazinon-derivate |
| ATE194835T1 (de) * | 1990-04-25 | 2000-08-15 | Nissan Chemical Ind Ltd | Pyridazinonderivat |
| JPH0517357A (ja) * | 1991-07-05 | 1993-01-26 | Nissan Chem Ind Ltd | 血小板減少療法剤 |
| IL110040A (en) * | 1993-06-29 | 2000-07-16 | Nissan Chemical Ind Ltd | Pyridazinone derivatives their preparation and pharmaceutical compositions comprising them |
| KR960704853A (ko) * | 1993-09-06 | 1996-10-09 | 아끼자와 다까시 | 피리다지논 유도체 또는 그의 염, 그의 제조 방법 및 그를 함유하는 항쇼크제 (Pyridazinone Derivatives or their Salts, Processes for their Production, and Anti-Shock Agents Containing Them) |
| NZ270130A (en) * | 1993-12-16 | 1995-12-21 | Nihon Nohyaku Co Ltd | Pyridazinone derivatives, preparation and pharmaceutical compositions thereof |
| ES2147841T3 (es) * | 1994-01-25 | 2000-10-01 | Nissan Chemical Ind Ltd | Derivados de piridazinona. |
| IL112695A (en) * | 1994-02-22 | 1999-04-11 | Green Cross Corp | Pharmaceutical compositions containing pyridazinone derivatives |
| DE19516350A1 (de) * | 1995-05-04 | 1996-11-07 | Du Pont Deutschland | Photothermographisches lichtempfindliches Aufzeichnungsmaterial mit vermindertem Schleier |
| CA2353956C (en) * | 1998-12-07 | 2008-10-28 | Nissan Chemical Industries, Ltd. | Remedial agent for erectile dysfunction |
| US20040106794A1 (en) | 2001-04-16 | 2004-06-03 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
| US7132445B2 (en) | 2001-04-16 | 2006-11-07 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
| EP1434775A1 (en) | 2001-10-12 | 2004-07-07 | Schering Corporation | 3,4-di-substituted maleimide compounds as cxc-chemokine receptor antagonists |
| US6878709B2 (en) * | 2002-01-04 | 2005-04-12 | Schering Corporation | 3,4-di-substituted pyridazinediones as CXC chemokine receptor antagonists |
| BR0308739A (pt) | 2002-03-18 | 2005-01-11 | Schering Corp | Tratamentos em combinação para doenças mediadas por quimiocina |
| US20040186142A1 (en) | 2002-10-09 | 2004-09-23 | Schering Corporation Pharmacopeia, Inc. | Thiadiazoledioxides and thiadiazoleoxides as CXC- and CC- chemokine receptor ligands |
| EP1694659B8 (en) | 2003-12-19 | 2008-10-08 | Schering Corporation | Thiadiazoles as cxc- and cc- chemokine receptor ligands |
| US7671212B2 (en) | 2003-12-22 | 2010-03-02 | Schering Corporation | Isothiazole dioxides as CXC- and CC-chemokine receptor ligands |
| CN101253180B (zh) | 2005-06-29 | 2011-08-03 | 先灵公司 | 作为cxc-化学活素受体配体的5，6-二取代的*二唑吡嗪和噻二唑吡嗪 |
| MX2008000366A (es) | 2005-06-29 | 2008-03-07 | Schering Corp | Oxadiazoles di-sustituidos como ligandos del receptor cxc-quimiocina. |
| CA3113061A1 (en) * | 2018-09-27 | 2020-04-02 | Fmc Corporation | Intermediates for preparing herbicidal pyridazinones |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA784639A (en) * | 1968-05-07 | C. Olson Harold | Herbicidal compositions | |
| FR1441438A (fr) * | 1963-11-13 | 1966-06-10 | Basf Ag | Procédé pour la préparation de nitro-4 amino-5 pyridazones-6 |
| FR1413955A (fr) * | 1964-06-03 | 1965-10-15 | Basf Ag | Procédé pour la préparation d'amino-4 halogéno-5 pyridazones-6 |
| US4296120A (en) * | 1980-08-28 | 1981-10-20 | Pfizer Inc. | (Carboxy-oxo-pyrrolidino)phenylalkenamides and esters thereof as SRS-A antagonists |
| EP0186817B1 (en) * | 1984-12-10 | 1989-08-02 | Nissan Chemical Industries Ltd. | 3(2h)pyridazinone, process for its preparation and anti-allergic agent containing it |
| JPH0641454B2 (ja) * | 1985-02-27 | 1994-06-01 | 日産化学工業株式会社 | ピリダジノン誘導体 |
| US4892947A (en) * | 1985-04-27 | 1990-01-09 | Nissan Chemical Industries Ltd. | 3(2H)Pyridazinone, process for its preparation and anti-allergic agent containing it |
-
1988
- 1988-01-15 US US07/144,173 patent/US4978665A/en not_active Expired - Fee Related
- 1988-01-15 HU HU88152A patent/HU198696B/hu not_active IP Right Cessation
- 1988-01-18 CA CA000556722A patent/CA1324792C/en not_active Expired - Fee Related
- 1988-01-18 ZA ZA880309A patent/ZA88309B/xx unknown
- 1988-01-19 AU AU10396/88A patent/AU597141B2/en not_active Ceased
- 1988-01-19 DD DD88312298A patent/DD287497A5/de not_active IP Right Cessation
- 1988-01-19 SU SU884355078A patent/SU1584750A3/ru active
- 1988-01-20 AT AT88100798T patent/ATE83773T1/de not_active IP Right Cessation
- 1988-01-20 DE DE8888100798A patent/DE3876813D1/de not_active Expired - Fee Related
- 1988-01-20 DE DE3876813T patent/DE3876813T4/de not_active Expired - Lifetime
- 1988-01-20 EP EP88100798A patent/EP0275997B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0275997B1 (en) | 1992-12-23 |
| HUT46313A (en) | 1988-10-28 |
| CA1324792C (en) | 1993-11-30 |
| AU1039688A (en) | 1988-07-21 |
| ATE83773T1 (de) | 1993-01-15 |
| EP0275997A1 (en) | 1988-07-27 |
| DE3876813T2 (de) | 1993-04-29 |
| DE3876813T4 (de) | 1995-05-11 |
| AU597141B2 (en) | 1990-05-24 |
| HU198696B (en) | 1989-11-28 |
| DE3876813D1 (de) | 1993-02-04 |
| DD287497A5 (de) | 1991-02-28 |
| US4978665A (en) | 1990-12-18 |
| SU1584750A3 (ru) | 1990-08-07 |
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