DE3876813D1 - 3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a. - Google Patents
3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a.Info
- Publication number
- DE3876813D1 DE3876813D1 DE8888100798A DE3876813A DE3876813D1 DE 3876813 D1 DE3876813 D1 DE 3876813D1 DE 8888100798 A DE8888100798 A DE 8888100798A DE 3876813 A DE3876813 A DE 3876813A DE 3876813 D1 DE3876813 D1 DE 3876813D1
- Authority
- DE
- Germany
- Prior art keywords
- hydrogen
- alkyl
- branched
- straight chained
- pyridazinone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical compound OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 11
- 239000001257 hydrogen Substances 0.000 abstract 11
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 10
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 6
- 229910052736 halogen Chemical group 0.000 abstract 3
- 150000002367 halogens Chemical group 0.000 abstract 3
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Chemical group 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1023187 | 1987-01-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3876813D1 true DE3876813D1 (de) | 1993-02-04 |
Family
ID=11744513
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8888100798A Expired - Fee Related DE3876813D1 (de) | 1987-01-20 | 1988-01-20 | 3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a. |
| DE3876813T Expired - Lifetime DE3876813T4 (de) | 1987-01-20 | 1988-01-20 | 3(2H)Pyridazinon, Verfahren zu dessen Herstellung und dieses enthaltendes Mittel gegen SRS-A. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3876813T Expired - Lifetime DE3876813T4 (de) | 1987-01-20 | 1988-01-20 | 3(2H)Pyridazinon, Verfahren zu dessen Herstellung und dieses enthaltendes Mittel gegen SRS-A. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4978665A (de) |
| EP (1) | EP0275997B1 (de) |
| AT (1) | ATE83773T1 (de) |
| AU (1) | AU597141B2 (de) |
| CA (1) | CA1324792C (de) |
| DD (1) | DD287497A5 (de) |
| DE (2) | DE3876813D1 (de) |
| HU (1) | HU198696B (de) |
| SU (1) | SU1584750A3 (de) |
| ZA (1) | ZA88309B (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0641455B2 (ja) * | 1984-12-10 | 1994-06-01 | 日産化学工業株式会社 | ピリダジノン誘導体 |
| IE62890B1 (en) * | 1988-12-06 | 1995-03-08 | Hafslund Nycomed Pharma | New piperazinylalkyl-3(2h)-pyridazinones process for the preparation thereof and the use thereof as agents lowering blood pressure |
| JPH02256668A (ja) * | 1988-12-20 | 1990-10-17 | Nissan Chem Ind Ltd | ピリダジノン誘導体 |
| DE4009761A1 (de) * | 1989-07-28 | 1991-01-31 | Bayer Ag | 2h-pyridazinon-derivate |
| DK0482208T3 (da) * | 1990-04-25 | 2000-09-18 | Nissan Chemical Ind Ltd | Pyridazinonderivat |
| JPH0517357A (ja) * | 1991-07-05 | 1993-01-26 | Nissan Chem Ind Ltd | 血小板減少療法剤 |
| IL110040A (en) * | 1993-06-29 | 2000-07-16 | Nissan Chemical Ind Ltd | Pyridazinone derivatives their preparation and pharmaceutical compositions comprising them |
| AU681694B2 (en) * | 1993-09-06 | 1997-09-04 | Ishihara Sangyo Kaisha Ltd. | Pyridazinone derivatives or their salts, processes for theirproduction, and anti-shock agents containing them |
| TW326041B (en) * | 1993-12-16 | 1998-02-01 | Nippon Nouyaku Kk | Pyridazinone derivatives, their production process and their use for inhibition of platelet aggregation |
| WO1995019969A1 (en) * | 1994-01-25 | 1995-07-27 | Nissan Chemical Industries, Ltd. | Pyridazinone derivative |
| IL112695A (en) * | 1994-02-22 | 1999-04-11 | Green Cross Corp | Pharmaceutical compositions containing pyridazinone derivatives |
| DE19516350A1 (de) * | 1995-05-04 | 1996-11-07 | Du Pont Deutschland | Photothermographisches lichtempfindliches Aufzeichnungsmaterial mit vermindertem Schleier |
| CZ20012020A3 (cs) * | 1998-12-07 | 2001-10-17 | Nissan Chemical Industries, Ltd. | Činidlo pro léčbu erektilní dysfunkce |
| US7132445B2 (en) | 2001-04-16 | 2006-11-07 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
| US20040106794A1 (en) | 2001-04-16 | 2004-06-03 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
| CN1599734A (zh) | 2001-10-12 | 2005-03-23 | 先灵公司 | 作为cxc趋化因子受体拮抗剂的3,4－二取代的马来酰亚胺化合物 |
| US6878709B2 (en) * | 2002-01-04 | 2005-04-12 | Schering Corporation | 3,4-di-substituted pyridazinediones as CXC chemokine receptor antagonists |
| WO2003080053A1 (en) | 2002-03-18 | 2003-10-02 | Schering Corporation | Combination treatments for chemokine-mediated diseases |
| EP1551818B1 (de) | 2002-10-09 | 2009-02-04 | Schering Corporation | Thiadiazoldioxide und thiadiazoloxide als cxc- und cc-chemokinrezeptor liganden |
| DE602004016211D1 (en) | 2003-12-19 | 2008-10-09 | Schering Corp | Thiadiazole als cxc- und cc-chemokinrezeptorliganden |
| WO2005068460A1 (en) | 2003-12-22 | 2005-07-28 | Schering Corporation | Isothiazole dioxides as cxc- and cc- chemokine receptor ligands |
| US7718678B2 (en) | 2005-06-29 | 2010-05-18 | Schering Corporation | Di-substituted oxadiazoles as CXC-chemokine receptor ligands |
| DE602006017849D1 (de) | 2005-06-29 | 2010-12-09 | Schering Corp | 5,6-disubstituierte oxadiazolopyrazine und thiadiazolopyrazine als liganden des cxc-chemokinrezeptors |
| MY202046A (en) * | 2018-09-27 | 2024-03-30 | Fmc Corp | Intermediates for Preparing Herbicidal Pyridazinones |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA784639A (en) * | 1968-05-07 | C. Olson Harold | Herbicidal compositions | |
| FR1441438A (fr) * | 1963-11-13 | 1966-06-10 | Basf Ag | Procédé pour la préparation de nitro-4 amino-5 pyridazones-6 |
| FR1413955A (fr) * | 1964-06-03 | 1965-10-15 | Basf Ag | Procédé pour la préparation d'amino-4 halogéno-5 pyridazones-6 |
| US4296120A (en) * | 1980-08-28 | 1981-10-20 | Pfizer Inc. | (Carboxy-oxo-pyrrolidino)phenylalkenamides and esters thereof as SRS-A antagonists |
| JPH0641455B2 (ja) * | 1984-12-10 | 1994-06-01 | 日産化学工業株式会社 | ピリダジノン誘導体 |
| JPH0641454B2 (ja) * | 1985-02-27 | 1994-06-01 | 日産化学工業株式会社 | ピリダジノン誘導体 |
| US4892947A (en) * | 1985-04-27 | 1990-01-09 | Nissan Chemical Industries Ltd. | 3(2H)Pyridazinone, process for its preparation and anti-allergic agent containing it |
-
1988
- 1988-01-15 US US07/144,173 patent/US4978665A/en not_active Expired - Fee Related
- 1988-01-15 HU HU88152A patent/HU198696B/hu not_active IP Right Cessation
- 1988-01-18 ZA ZA880309A patent/ZA88309B/xx unknown
- 1988-01-18 CA CA000556722A patent/CA1324792C/en not_active Expired - Fee Related
- 1988-01-19 SU SU884355078A patent/SU1584750A3/ru active
- 1988-01-19 DD DD88312298A patent/DD287497A5/de not_active IP Right Cessation
- 1988-01-19 AU AU10396/88A patent/AU597141B2/en not_active Ceased
- 1988-01-20 DE DE8888100798A patent/DE3876813D1/de not_active Expired - Fee Related
- 1988-01-20 DE DE3876813T patent/DE3876813T4/de not_active Expired - Lifetime
- 1988-01-20 AT AT88100798T patent/ATE83773T1/de not_active IP Right Cessation
- 1988-01-20 EP EP88100798A patent/EP0275997B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ZA88309B (en) | 1988-07-01 |
| EP0275997A1 (de) | 1988-07-27 |
| ATE83773T1 (de) | 1993-01-15 |
| DD287497A5 (de) | 1991-02-28 |
| HUT46313A (en) | 1988-10-28 |
| US4978665A (en) | 1990-12-18 |
| AU597141B2 (en) | 1990-05-24 |
| EP0275997B1 (de) | 1992-12-23 |
| DE3876813T4 (de) | 1995-05-11 |
| DE3876813T2 (de) | 1993-04-29 |
| CA1324792C (en) | 1993-11-30 |
| SU1584750A3 (ru) | 1990-08-07 |
| HU198696B (en) | 1989-11-28 |
| AU1039688A (en) | 1988-07-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3876813D1 (de) | 3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a. | |
| JPS568361A (en) | Pyroglutamic acid derivative and analogue | |
| FI892787A0 (fi) | Analogiamenetelmä terapeuttisesti käyttökelpoisten 1-indolyylialkyyli-4-(substituoitu pyridinyyli)piperatsiinien valmistamiseksi | |
| TW368501B (en) | 7-(2-aminoethyl)-benzothiazolones | |
| FI893467A0 (fi) | Menetelmä lääkeaineena käyttökelpoisten 4-oksokinoliini-3-karboksyylihapon johdannaisten valmistamiseksi | |
| ATE57699T1 (de) | Pyridoncarbonsauere-derivate und verfahren zu ihrer herstellung. | |
| GB0018272D0 (en) | Chemical compounds IV | |
| CA2203237A1 (en) | Aminotetrazole derivatives useful as nitric oxide synthase inhibitors | |
| ATE164582T1 (de) | 1-methylcarbapenemderivate und verfahren zu ihrer herstellung | |
| CO4980887A1 (es) | Nueva 3,4-diariltiazolina-2-uno o 2-tiono derivados, sus metodos de preparacion y su uso terapeutico | |
| ATE44748T1 (de) | 4-substituierte 6-alkylidene-androsten-3,17-dion- derivate und verfahren zu ihrer herstellung. | |
| ES2073258T3 (es) | Nuevos derivados de la urea, su preparacion y su aplicacion en terapeutica. | |
| NZ221699A (en) | Pyridazinone derivatives; pharmaceutical compositions and intermediates | |
| ATE34394T1 (de) | Therapeutisch aktive di-, tri-, tetra- und penta- aza-indene. | |
| GR3030234T3 (en) | 4-Phenylcarbamoyl-3-isoxazolecarboxylic acid derivatives with antiinflammatory activity | |
| AU576887B2 (en) | 1,6-naphthyridine derivatives | |
| MY109714A (en) | Process for preparing 8-chloroquinolone derivatives | |
| ATE58135T1 (de) | 1,3-oxathianderivate. | |
| ES8103740A1 (es) | Procedimiento para la obtencion de nuevos derivados de la piperacina metanimina | |
| ES471895A1 (es) | Procedimiento para preparar derivados de benzamidina | |
| NZ504299A (en) | 1-aza-2-alkyl-6-aryl-cycloalkane compounds, a process for their preparation and pharmaceutical compositions containing them | |
| ATE52509T1 (de) | Thiazolidinderivate und verfahren zu ihrer herstellung. | |
| ATE139767T1 (de) | Verfahren zur herstellung 5-pyrazolomerkaptan- derivate und dessen zwischenprodukte | |
| ATE53839T1 (de) | 2,3-dihydro-3-phenyl-benzofuran-2-onacetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. | |
| ES8307812A1 (es) | Un procedimiento para la preparacion de nuevos amidin derivados del acido clavulawilo. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |