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ZA863762B - Hypoglycemic thiazolidinediones - Google Patents

Hypoglycemic thiazolidinediones

Info

Publication number
ZA863762B
ZA863762B ZA863762A ZA863762A ZA863762B ZA 863762 B ZA863762 B ZA 863762B ZA 863762 A ZA863762 A ZA 863762A ZA 863762 A ZA863762 A ZA 863762A ZA 863762 B ZA863762 B ZA 863762B
Authority
ZA
South Africa
Prior art keywords
benzo
hypoglycemic
dihydro
hypoglycemic thiazolidinediones
thiazolidinediones
Prior art date
Application number
ZA863762A
Other languages
English (en)
Inventor
James Frederick Eggler
Gerald Fagan Holland
Michael Ross Johnson
Robert Alfred Volkmann
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA863762B publication Critical patent/ZA863762B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Emergency Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrane Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Soil Working Implements (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Detergent Compositions (AREA)
  • Saccharide Compounds (AREA)
ZA863762A 1985-05-21 1986-05-20 Hypoglycemic thiazolidinediones ZA863762B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1985/000962 WO1986007056A1 (en) 1985-05-21 1985-05-21 Hypoglycemic thiazolidinediones

Publications (1)

Publication Number Publication Date
ZA863762B true ZA863762B (en) 1988-05-25

Family

ID=22188690

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA863762A ZA863762B (en) 1985-05-21 1986-05-20 Hypoglycemic thiazolidinediones

Country Status (26)

Country Link
US (1) US4703052A (xx)
EP (1) EP0207605B1 (xx)
JP (1) JPS61271287A (xx)
KR (1) KR870000903B1 (xx)
CN (1) CN1007248B (xx)
AT (1) ATE50256T1 (xx)
AU (2) AU560179B2 (xx)
CA (1) CA1279320C (xx)
DD (1) DD261154A5 (xx)
DE (1) DE3668892D1 (xx)
DK (1) DK233586A (xx)
EG (1) EG18043A (xx)
ES (1) ES8707210A1 (xx)
FI (1) FI89268C (xx)
GR (1) GR861297B (xx)
HU (1) HU210339B (xx)
IE (1) IE58674B1 (xx)
IL (1) IL78831A (xx)
MY (1) MY108496A (xx)
NO (1) NO166448C (xx)
PH (2) PH22313A (xx)
PL (1) PL147479B1 (xx)
PT (1) PT82610B (xx)
WO (1) WO1986007056A1 (xx)
YU (1) YU44573B (xx)
ZA (1) ZA863762B (xx)

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US5130379A (en) * 1988-03-08 1992-07-14 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
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WO1989008651A1 (en) * 1988-03-08 1989-09-21 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
HU217432B (hu) * 1988-03-08 2000-01-28 Pfizer Inc. Eljárás tiazolidin-dion-származékok és az ezeket tartalmazó gyógyszerkészítmények előállítására, a vegyületek és a készítmények
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US5053420A (en) * 1989-10-13 1991-10-01 Pershadsingh Harrihar A Thiazolidine derivatives for the treatment of hypertension
WO1991007107A1 (en) * 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
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US5089637A (en) * 1990-03-21 1992-02-18 Pfizer Inc. Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde
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US5037842A (en) * 1990-06-05 1991-08-06 Pfizer Inc. Oxa- and thiazolidinedione hypoglycemic and hypocholesterolemic agents
US5089514A (en) * 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
ES2067945T3 (es) * 1990-08-23 1995-04-01 Pfizer Derivados de hidroxiurea hipoglicemica.
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TW222626B (xx) 1991-07-22 1994-04-21 Pfizer
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JP2845743B2 (ja) * 1992-12-28 1999-01-13 三菱化学株式会社 新規なナフタレン誘導体
JP3195455B2 (ja) * 1993-01-06 2001-08-06 ウェルファイド株式会社 キノリン−３−酢酸誘導体、その製造法と用途
DE4317320A1 (de) * 1993-05-25 1994-12-01 Boehringer Mannheim Gmbh Neue Thiazolidindione und diese enthaltende Arzneimittel
US6046222A (en) * 1993-09-15 2000-04-04 Warner-Lambert Company Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus
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JP2001514663A (ja) * 1997-03-12 2001-09-11 エスモンド，ロバート ダブリュー． アルツハイマー病を処置または予防するための方法
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RU2176999C2 (ru) * 1997-10-02 2001-12-20 Санкио Компани, Лимитед Производные амидокарбоновой кислоты, фармацевтическая композиция на их основе и способ снижения глюкозы в крови
HUP9902721A2 (hu) 1997-11-25 1999-12-28 The Procter & Gamble Co. Tömény textillágyító készítmény és ehhez alkalmazható magas telítetlenségű textillágyító vegyület
AU1507799A (en) * 1997-12-16 1999-07-05 Sankyo Company Limited Leukemia remedy
US20040058873A1 (en) * 1998-03-12 2004-03-25 Esmond Robert W. Method for treating or preventing Alzheimer's disease
AU1740900A (en) * 1998-11-20 2000-06-13 Genentech Inc. Method of inhibiting angiogenesis
US6191154B1 (en) 1998-11-27 2001-02-20 Case Western Reserve University Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases
US5968960A (en) * 1999-01-14 1999-10-19 The Regents Of The University Of California Use of thiazolidinediones to ameliorate the adverse consequences of myocardial ischemia on myocardial function and metabolism
JP2001072592A (ja) 1999-07-01 2001-03-21 Kyowa Hakko Kogyo Co Ltd テロメラーゼ阻害剤
WO2001007031A1 (en) * 1999-07-26 2001-02-01 Shionogi & Co., Ltd. Benzene derivatives and immunopotentiating compositions or drug-sensitivity restoring agents containing the same
CO5200844A1 (es) 1999-09-17 2002-09-27 Novartis Ag Una combinacion que comprende nateglinida y cuando por menos otro compuesto antidiabetico usada para el tratamiento de desordenes metabolicos, especialmente diabetes, o de una enfermedad o condicion asociada con dibetes
US6878749B2 (en) 1999-09-17 2005-04-12 Novartis Ag Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
US6559188B1 (en) 1999-09-17 2003-05-06 Novartis Ag Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
ES2487897T3 (es) 2000-01-21 2014-08-25 Novartis Ag Combinaciones que consisten de inhibidores de la dipeptidilpeptidasa-IV y agentes antidiabéticos
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WO2004110458A1 (en) * 2003-05-16 2004-12-23 Board Of Regents, The University Of Texas System Phenothiazine enantiomers as agents for the prevention of bone loss
CL2008000684A1 (es) 2007-03-09 2008-08-01 Indigene Pharmaceuticals Inc Composicion farmaceutica que comprende metformina r-(+) lipoato y un inhibidor de reductasa hmg-coa; formulacion de dosis unitaria; y uso en el tratamiento de una complicacion diabetica.
HK1214760A1 (zh) 2012-11-05 2016-08-05 Commissariat à l'énergie atomique et aux énergies alternatives 用於消除体内血癌干细胞以及用於防止血癌复发的抗癌试剂如酪氨酸激酶和stat5拮抗剂优选为噻唑烷二酮的组合
CN116535379B (zh) * 2023-06-29 2023-09-19 希格生科（深圳）有限公司 化合物及其医药用途

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JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS5697277A (en) * 1980-01-07 1981-08-05 Takeda Chem Ind Ltd Thiazolidine derivative
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EP0117035B1 (en) 1983-01-17 1989-08-16 Pfizer Inc. Aldose reductase inhibiting 5-(2-alkoxyphenyl)thiazolidinediones
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
FI91869C (fi) * 1987-03-18 1994-08-25 Tanabe Seiyaku Co Menetelmä antidiabeettisena aineena käytettävien bensoksatsolijohdannaisten valmistamiseksi

Also Published As

Publication number Publication date
EP0207605A1 (en) 1987-01-07
FI89268C (fi) 1993-09-10
IL78831A (en) 1990-11-29
MY108496A (en) 1996-10-31
PT82610A (en) 1986-06-01
FI89268B (fi) 1993-05-31
AU560179B2 (en) 1987-04-02
KR860009010A (ko) 1986-12-19
GR861297B (en) 1986-09-16
DD261154A5 (de) 1988-10-19
NO870241L (no) 1987-03-20
CA1279320C (en) 1991-01-22
IL78831A0 (en) 1986-09-30
JPH0586953B2 (xx) 1993-12-14
HUT45247A (en) 1988-06-28
NO166448B (no) 1991-04-15
ATE50256T1 (de) 1990-02-15
PT82610B (pt) 1988-11-30
WO1986007056A1 (en) 1986-12-04
AU583991B2 (en) 1989-05-11
AU5758086A (en) 1987-01-08
PH22313A (en) 1988-07-29
NO166448C (no) 1991-07-24
DK233586A (da) 1986-11-22
DK233586D0 (da) 1986-05-20
CN86104075A (zh) 1987-03-11
ES8707210A1 (es) 1987-07-16
ES555147A0 (es) 1987-07-16
YU44573B (en) 1990-10-31
FI870219L (fi) 1987-01-20
HU210339B (en) 1995-03-28
US4703052A (en) 1987-10-27
PH25226A (en) 1991-03-27
KR870000903B1 (ko) 1987-05-04
NO870241D0 (no) 1987-01-20
EP0207605B1 (en) 1990-02-07
IE861336L (en) 1986-11-21
DE3668892D1 (en) 1990-03-15
EG18043A (en) 1992-11-30
YU83786A (en) 1987-12-31
PL147479B1 (en) 1989-06-30
JPS61271287A (ja) 1986-12-01
AU7507487A (en) 1987-10-15
CN1007248B (zh) 1990-03-21
IE58674B1 (en) 1993-11-03
FI870219A0 (fi) 1987-01-20

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