ZA200810129B - Substituted phenyl methanone derivatives - Google Patents
Substituted phenyl methanone derivativesInfo
- Publication number
- ZA200810129B ZA200810129B ZA200810129A ZA200810129A ZA200810129B ZA 200810129 B ZA200810129 B ZA 200810129B ZA 200810129 A ZA200810129 A ZA 200810129A ZA 200810129 A ZA200810129 A ZA 200810129A ZA 200810129 B ZA200810129 B ZA 200810129B
- Authority
- ZA
- South Africa
- Prior art keywords
- substituted phenyl
- phenyl methanone
- methanone derivatives
- derivatives
- substituted
- Prior art date
Links
- HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical class O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/16—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with acylated ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06115916 | 2006-06-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200810129B true ZA200810129B (en) | 2010-04-28 |
Family
ID=38474053
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200810129A ZA200810129B (en) | 2006-06-22 | 2008-11-27 | Substituted phenyl methanone derivatives |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7951836B2 (xx) |
| EP (1) | EP2035371B1 (xx) |
| JP (1) | JP4937347B2 (xx) |
| KR (1) | KR101072796B1 (xx) |
| CN (1) | CN101472886B (xx) |
| AR (1) | AR061560A1 (xx) |
| AU (1) | AU2007263083B2 (xx) |
| BR (1) | BRPI0713584A2 (xx) |
| CA (1) | CA2653355C (xx) |
| CL (1) | CL2007001802A1 (xx) |
| ES (1) | ES2406085T3 (xx) |
| IL (1) | IL195478A0 (xx) |
| MX (1) | MX2008015932A (xx) |
| NO (1) | NO20085155L (xx) |
| RU (1) | RU2437872C2 (xx) |
| TW (1) | TWI342308B (xx) |
| WO (1) | WO2007147770A2 (xx) |
| ZA (1) | ZA200810129B (xx) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008527016A (ja) * | 2005-01-18 | 2008-07-24 | エフ．ホフマン−ラ ロシュ アーゲー | 神経及び神経精神病の疾患の治療のためのグリシントランスポーター１（ＧｌｙＴ−１）阻害剤としての２，５−二置換フェニルメタノン誘導体 |
| US9012489B2 (en) * | 2011-08-03 | 2015-04-21 | Boehringer Ingelheim International Gmbh | Phenyl-3-aza-bicyclo[3.1.0]hex-3-yl-methanones and the use thereof as medicament |
| WO2015164520A1 (en) | 2014-04-24 | 2015-10-29 | Dart Neuroscience, Llc | Substituted 2,4,5,6-tetrahydropyrrolo[3,4-c] pyrazole and 4,5,6,7-tetrahydro-2h-pyrazolo [4,3-c] pyridine compounds as glyt1 inhibitors |
| US10040759B2 (en) | 2014-11-05 | 2018-08-07 | Dart Neuroscience (Cayman) Ltd. | Substituted azetidinyl compounds as GlyT1 inhibitors |
| US12059408B2 (en) | 2020-08-13 | 2024-08-13 | Boehringer Ingelheim International Gmbh | Treatment of cognitive impairment associated with schizophrenia |
| BR112023004774A2 (pt) | 2020-10-13 | 2023-04-25 | Boehringer Ingelheim Int | Processo de retrabalho |
| WO2025106383A1 (en) * | 2023-11-17 | 2025-05-22 | Merck Sharp & Dohme Llc | Pyrrolidinyl derivatives useful as hcn1/hcn 2 modulators |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI243173B (en) * | 1999-11-17 | 2005-11-11 | Akzo Nobel Nv | Spiro[2H-1-benzopyran-2,4'-piperidine] derivatives |
| MXPA06001665A (es) | 2003-08-11 | 2006-04-28 | Hoffmann La Roche | Piperazina con grupo fenilo sustituido -or y su uso como inhibidores del transportador de glicina 1 (glyt-1). |
| DK1703909T3 (da) * | 2003-09-09 | 2009-06-22 | Hoffmann La Roche | 1-benzoyl-piperazinderivater som glycinoptagelsesinhibitorer til behandling af psykoser |
| US7745630B2 (en) * | 2003-12-22 | 2010-06-29 | Justin Stephen Bryans | Triazolyl piperidine arginine vasopressin receptor modulators |
| US7485637B2 (en) * | 2005-01-04 | 2009-02-03 | Hoffmann-La Roche Inc. | Benzoyl-tetrahydropiperidine derivatives |
| JP2008527016A (ja) * | 2005-01-18 | 2008-07-24 | エフ．ホフマン−ラ ロシュ アーゲー | 神経及び神経精神病の疾患の治療のためのグリシントランスポーター１（ＧｌｙＴ−１）阻害剤としての２，５−二置換フェニルメタノン誘導体 |
-
2007
- 2007-06-14 BR BRPI0713584-0A patent/BRPI0713584A2/pt not_active IP Right Cessation
- 2007-06-14 AU AU2007263083A patent/AU2007263083B2/en not_active Expired - Fee Related
- 2007-06-14 MX MX2008015932A patent/MX2008015932A/es active IP Right Grant
- 2007-06-14 CN CN2007800223953A patent/CN101472886B/zh not_active Expired - Fee Related
- 2007-06-14 RU RU2008148165/04A patent/RU2437872C2/ru not_active IP Right Cessation
- 2007-06-14 JP JP2009515835A patent/JP4937347B2/ja not_active Expired - Fee Related
- 2007-06-14 KR KR1020087030949A patent/KR101072796B1/ko not_active Expired - Fee Related
- 2007-06-14 WO PCT/EP2007/055871 patent/WO2007147770A2/en not_active Ceased
- 2007-06-14 EP EP07730150A patent/EP2035371B1/en not_active Not-in-force
- 2007-06-14 ES ES07730150T patent/ES2406085T3/es active Active
- 2007-06-14 CA CA2653355A patent/CA2653355C/en not_active Expired - Fee Related
- 2007-06-15 US US11/818,676 patent/US7951836B2/en not_active Expired - Fee Related
- 2007-06-20 CL CL200701802A patent/CL2007001802A1/es unknown
- 2007-06-21 TW TW096122343A patent/TWI342308B/zh active
- 2007-06-21 AR ARP070102729A patent/AR061560A1/es unknown
-
2008
- 2008-11-24 IL IL195478A patent/IL195478A0/en not_active IP Right Cessation
- 2008-11-27 ZA ZA200810129A patent/ZA200810129B/xx unknown
- 2008-12-11 NO NO20085155A patent/NO20085155L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20085155L (no) | 2009-01-15 |
| EP2035371B1 (en) | 2013-03-06 |
| CL2007001802A1 (es) | 2008-05-23 |
| RU2008148165A (ru) | 2010-07-27 |
| WO2007147770A3 (en) | 2008-05-22 |
| JP2009541251A (ja) | 2009-11-26 |
| CA2653355A1 (en) | 2007-12-27 |
| RU2437872C2 (ru) | 2011-12-27 |
| CN101472886B (zh) | 2011-07-13 |
| KR101072796B1 (ko) | 2011-10-14 |
| CA2653355C (en) | 2014-04-15 |
| US7951836B2 (en) | 2011-05-31 |
| AU2007263083B2 (en) | 2012-10-04 |
| AU2007263083A1 (en) | 2007-12-27 |
| TW200808784A (en) | 2008-02-16 |
| EP2035371A2 (en) | 2009-03-18 |
| JP4937347B2 (ja) | 2012-05-23 |
| ES2406085T3 (es) | 2013-06-05 |
| BRPI0713584A2 (pt) | 2012-10-23 |
| TWI342308B (en) | 2011-05-21 |
| CN101472886A (zh) | 2009-07-01 |
| US20070299071A1 (en) | 2007-12-27 |
| MX2008015932A (es) | 2009-01-13 |
| WO2007147770A2 (en) | 2007-12-27 |
| AR061560A1 (es) | 2008-09-03 |
| IL195478A0 (en) | 2009-09-01 |
| KR20090015979A (ko) | 2009-02-12 |
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