ZA200703910B - N-[(3S)-pyrrolidin-3YL]-benzamide derivatives as monoamine re-uptake inhibitors - Google Patents

N-[(3S)-pyrrolidin-3YL]-benzamide derivatives as monoamine re-uptake inhibitors

Info

Publication number: ZA200703910B
Authority: ZA; South Africa
Prior art keywords: monoamine; pyrrolidin; uptake inhibitors; benzamide derivatives; benzamide
Prior art date: 2004-11-23

Application number

ZA200703910A

Other languages

English (en)

Inventor

Fish Paul Vincent

Ryckmans Thomas

Stobie Alan

Wakenhut Florian

Whitlock Gavin Alistair

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-11-23

Filing date

2007-05-15

Publication date

2008-09-25

2007-05-15 Application filed by Pfizer filed Critical Pfizer

2008-09-25 Publication of ZA200703910B publication Critical patent/ZA200703910B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Reproductive Health (AREA)
Neurosurgery (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Gynecology & Obstetrics (AREA)
Psychiatry (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ZA200703910A 2004-11-23 2007-05-15 N-[(3S)-pyrrolidin-3YL]-benzamide derivatives as monoamine re-uptake inhibitors ZA200703910B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0425766.3A GB0425766D0 (en)	2004-11-23	2004-11-23	Novel compounds

Publications (1)

Publication Number	Publication Date
ZA200703910B true ZA200703910B (en)	2008-09-25

Family

ID=33548739

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200703910A ZA200703910B (en)	2004-11-23	2007-05-15	N-[(3S)-pyrrolidin-3YL]-benzamide derivatives as monoamine re-uptake inhibitors

Country Status (26)

Country	Link
EP (1)	EP1817281A1 (xx)
JP (1)	JP4233596B2 (xx)
KR (1)	KR100886294B1 (xx)
CN (1)	CN101065355A (xx)
AP (1)	AP2007004003A0 (xx)
AR (1)	AR052243A1 (xx)
AU (1)	AU2005308534A1 (xx)
BR (1)	BRPI0518486A2 (xx)
CA (1)	CA2589258A1 (xx)
CR (1)	CR9171A (xx)
EA (1)	EA011217B1 (xx)
GB (1)	GB0425766D0 (xx)
GT (1)	GT200500337A (xx)
IL (1)	IL183191A0 (xx)
MA (1)	MA29038B1 (xx)
MX (1)	MX2007006138A (xx)
NL (2)	NL1030485C2 (xx)
NO (1)	NO20072486L (xx)
PA (1)	PA8653501A1 (xx)
PE (1)	PE20061056A1 (xx)
SV (1)	SV2006002311A (xx)
TN (1)	TNSN07201A1 (xx)
TW (1)	TWI300776B (xx)
UY (1)	UY29224A1 (xx)
WO (1)	WO2006056884A1 (xx)
ZA (1)	ZA200703910B (xx)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH628885A5 (en) *	1978-01-01	1982-03-31	Anphar Sa	Piperidine derivative
AP2005003467A0 (en) *	2003-06-17	2006-12-31	Pfizer	N-pyrrolidin-3-YL-amide derivatives as serotonin and noradrenaline reuptake inhibitors.
GB0314054D0 (en) *	2003-06-17	2003-07-23	Pfizer Ltd	Amide derivatives as selective serotonin re-uptake inhibitors

2004
- 2004-11-23 GB GBGB0425766.3A patent/GB0425766D0/en not_active Ceased
2005
- 2005-11-18 JP JP2007542360A patent/JP4233596B2/ja not_active Expired - Fee Related
- 2005-11-18 BR BRPI0518486-0A patent/BRPI0518486A2/pt not_active IP Right Cessation
- 2005-11-18 EP EP05808510A patent/EP1817281A1/en not_active Withdrawn
- 2005-11-18 KR KR1020077014351A patent/KR100886294B1/ko not_active Expired - Fee Related
- 2005-11-18 EA EA200700920A patent/EA011217B1/ru not_active IP Right Cessation
- 2005-11-18 AU AU2005308534A patent/AU2005308534A1/en not_active Abandoned
- 2005-11-18 MX MX2007006138A patent/MX2007006138A/es active IP Right Grant
- 2005-11-18 AP AP2007004003A patent/AP2007004003A0/xx unknown
- 2005-11-18 CA CA002589258A patent/CA2589258A1/en not_active Abandoned
- 2005-11-18 WO PCT/IB2005/003643 patent/WO2006056884A1/en not_active Ceased
- 2005-11-18 CN CNA2005800401025A patent/CN101065355A/zh active Pending
- 2005-11-21 PE PE2005001362A patent/PE20061056A1/es not_active Application Discontinuation
- 2005-11-21 AR ARP050104866A patent/AR052243A1/es not_active Application Discontinuation
- 2005-11-22 UY UY29224A patent/UY29224A1/es not_active Application Discontinuation
- 2005-11-22 GT GT200500337A patent/GT200500337A/es unknown
- 2005-11-22 NL NL1030485A patent/NL1030485C2/nl not_active IP Right Cessation
- 2005-11-22 TW TW094140922A patent/TWI300776B/zh active
- 2005-11-23 SV SV2005002311A patent/SV2006002311A/es unknown
- 2005-11-23 PA PA20058653501A patent/PA8653501A1/es unknown
2006
- 2006-10-27 NL NL1032760A patent/NL1032760C2/nl not_active IP Right Cessation
2007
- 2007-05-14 IL IL183191A patent/IL183191A0/en unknown
- 2007-05-15 ZA ZA200703910A patent/ZA200703910B/xx unknown
- 2007-05-15 NO NO20072486A patent/NO20072486L/no not_active Application Discontinuation
- 2007-05-22 TN TNP2007000201A patent/TNSN07201A1/fr unknown
- 2007-05-23 MA MA29935A patent/MA29038B1/fr unknown
- 2007-06-07 CR CR9171A patent/CR9171A/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
CR9171A (es)	2007-07-04
WO2006056884A1 (en)	2006-06-01
NL1032760C2 (nl)	2007-04-17
IL183191A0 (en)	2007-08-19
CN101065355A (zh)	2007-10-31
GB0425766D0 (en)	2004-12-22
NL1030485C2 (nl)	2006-11-07
JP4233596B2 (ja)	2009-03-04
BRPI0518486A2 (pt)	2008-11-18
PE20061056A1 (es)	2006-11-08
AU2005308534A1 (en)	2006-06-01
TW200626543A (en)	2006-08-01
SV2006002311A (es)	2006-09-14
KR100886294B1 (ko)	2009-03-04
NO20072486L (no)	2007-06-20
AP2007004003A0 (en)	2007-06-30
PA8653501A1 (es)	2006-06-02
UY29224A1 (es)	2006-06-30
GT200500337A (es)	2006-06-13
AR052243A1 (es)	2007-03-07
EA011217B1 (ru)	2009-02-27
JP2008520646A (ja)	2008-06-19
MX2007006138A (es)	2007-07-19
TNSN07201A1 (fr)	2008-11-21
NL1032760A1 (nl)	2006-12-13
EP1817281A1 (en)	2007-08-15
EA200700920A1 (ru)	2007-12-28
CA2589258A1 (en)	2006-06-01
NL1030485A1 (nl)	2006-05-24
MA29038B1 (fr)	2007-11-01
TWI300776B (en)	2008-09-11
KR20070086599A (ko)	2007-08-27

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