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ZA200704915B - Use of diketodithiopiperazine antibiotics for the preparation of antiangiogenic pharmaceutical compositions - Google Patents

Use of diketodithiopiperazine antibiotics for the preparation of antiangiogenic pharmaceutical compositions

Info

Publication number
ZA200704915B
ZA200704915B ZA200704915A ZA200704915A ZA200704915B ZA 200704915 B ZA200704915 B ZA 200704915B ZA 200704915 A ZA200704915 A ZA 200704915A ZA 200704915 A ZA200704915 A ZA 200704915A ZA 200704915 B ZA200704915 B ZA 200704915B
Authority
ZA
South Africa
Prior art keywords
preparation
pharmaceutical compositions
diketodithiopiperazine
antibiotics
antiangiogenic
Prior art date
Application number
ZA200704915A
Other languages
English (en)
Inventor
De Munari Sergio
Mario Grugni
Menta Ernesto
Cassin Mara
Colella Gennaro
Original Assignee
Cell Therapeutics Europe Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Therapeutics Europe Srl filed Critical Cell Therapeutics Europe Srl
Publication of ZA200704915B publication Critical patent/ZA200704915B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200704915A 2004-12-23 2005-12-14 Use of diketodithiopiperazine antibiotics for the preparation of antiangiogenic pharmaceutical compositions ZA200704915B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002477A ITMI20042477A1 (it) 2004-12-23 2004-12-23 Uso di antibiotici a strutura dichetoditiopiperazinica per la preparazione di composizioni farmaceutiche antiangiogeniche

Publications (1)

Publication Number Publication Date
ZA200704915B true ZA200704915B (en) 2008-11-26

Family

ID=35929666

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200704915A ZA200704915B (en) 2004-12-23 2005-12-14 Use of diketodithiopiperazine antibiotics for the preparation of antiangiogenic pharmaceutical compositions

Country Status (12)

Country Link
US (1) US20080255099A1 (fr)
EP (1) EP1827442A1 (fr)
JP (1) JP2008525336A (fr)
KR (1) KR20070102492A (fr)
CN (1) CN101083991A (fr)
AU (1) AU2005318535A1 (fr)
CA (1) CA2592002A1 (fr)
IL (1) IL184114A0 (fr)
IT (1) ITMI20042477A1 (fr)
MX (1) MX2007007503A (fr)
WO (1) WO2006066775A1 (fr)
ZA (1) ZA200704915B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008112014A1 (fr) * 2006-10-05 2008-09-18 Mayo Foundation For Medical Education And Research Procédés et compositions permettant de traiter le cancer
ES2325724B1 (es) 2008-03-11 2010-05-31 FUNDACION DE LA COMUNIDAD VALENCIANA "CENTRO DE INVESTIGACIONES PRINCIPE FELIPE" Composicion farmaceutica para inhibir el factor de transcripcion inducible por hipoxia. moduladores de procesos patologicos de angiogenesis, oncogenesis, inflamacion, apoptosis y terapia celular.
CN102216322A (zh) 2008-09-18 2011-10-12 纽约大学 用基于氢键替代的螺旋抑制HIF-1α和p300/CBP之间的相互作用
KR101157078B1 (ko) 2009-10-27 2012-06-21 한국과학기술연구원 아스퍼질러스 ｋｍｄ 901 균주, 이로부터 분리된 다이케토피페라진 화합물, 및 이를 함유하는 암 예방 또는 치료용 조성물
WO2012161799A1 (fr) * 2011-02-24 2012-11-29 Georgia Health Sciences University Research Institute, Inc Epidithiodioxopipérazines et leurs utilisations dans le traitement du cancer
EP2763670B1 (fr) 2011-10-03 2018-12-05 Universite Libre De Bruxelles Reactivation de l'expression de gènes vih pour le traitement d'une infection vih persistante
WO2013050405A1 (fr) * 2011-10-03 2013-04-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Méthodes et compositions pharmaceutiques pour le traitement de maladies à médiation par th2
US9765090B2 (en) 2011-11-25 2017-09-19 Ewha University-Industry Collaboration Foundation Epidithiodioxopiperazine compound or its derivatives, and the use thereof
US9255086B2 (en) 2012-02-16 2016-02-09 New York University Control of hypoxia-inducible gene expression with oligooxopiperazine nonpeptidic helix mimetics
US9416145B2 (en) * 2012-08-29 2016-08-16 University Of Southern California Compositions and methods for inhibiting activity of hypoxia-inducible transcription factor complex and its use for treatment of tumors
JP6465803B2 (ja) 2012-10-22 2019-02-06 シティ・オブ・ホープＣｉｔｙ ｏｆ Ｈｏｐｅ Ｅｔｐ誘導体
CN105229013B (zh) * 2013-05-24 2018-09-14 梨花女子大学校产学协力团 桥二硫双氧代哌嗪化合物或它的衍生物，及其用途
CN103550222A (zh) * 2013-11-05 2014-02-05 南京医科大学 毛壳素在制备预防和治疗糖尿病药物中的应用
US9636340B2 (en) 2013-11-12 2017-05-02 Ayyappan K. Rajasekaran Kinase inhibitors
KR102034243B1 (ko) * 2016-07-05 2019-10-21 바스테라 주식회사 에피디티오디옥소피페라진 화합물 또는 이의 유도체, 또는 이들의 약학적으로 허용가능한 염을 포함하는 폐동맥고혈압 예방 또는 치료용 약학적 조성물
JP7088912B2 (ja) 2016-09-15 2022-06-21 シティ・オブ・ホープ ジチオｅｔｐ誘導体
CN107261137B (zh) * 2017-05-22 2021-04-13 中国人民解放军第二军医大学 两种抗her2抗体-毛壳素偶联物及其制备方法和抗肿瘤应用
WO2019009646A1 (fr) * 2017-07-05 2019-01-10 바스테라 주식회사 Composé ou dérivé d'épidithiodioxopipérazine, ou composition pharmaceutique de prévention ou de traitement de l'hypertension pulmonaire, contenant des sels pharmaceutiquement acceptables de ce dernier
JP2022545732A (ja) * 2019-08-28 2022-10-28 バステラ カンパニー リミテッド エピジチオジオキソピペラジン誘導体又はその薬学的に許容される塩を含む、固形癌の予防又は治療用薬学的組成物
CN112626039B (zh) * 2020-12-22 2022-10-25 广东省微生物研究所（广东省微生物分析检测中心） 一种氧化还原酶GliT及其在抵抗真菌毒素中应用
CN119403810A (zh) * 2022-06-29 2025-02-07 瓦斯塞拉股份有限公司 化合物、含有它们的药物组合物及其用于治疗或预防血管疾病的医疗用途
CN116473977A (zh) * 2023-05-12 2023-07-25 南充市中心医院 毛壳素在制备治疗食管鳞癌的药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ212051A (en) * 1984-05-18 1988-10-28 Univ Australian Immune response suppression; certain epipolythio- dioxopiperazine derivatives and their preparation
JPS61277617A (ja) * 1985-05-31 1986-12-08 Yakult Honsha Co Ltd 坑血小板凝集剤
KR19990082168A (ko) * 1996-12-02 1999-11-25 에가시라 구니오 글리오톡신 유도체 및 이를 함유하는 항암제

Also Published As

Publication number Publication date
AU2005318535A1 (en) 2006-06-29
KR20070102492A (ko) 2007-10-18
CN101083991A (zh) 2007-12-05
MX2007007503A (es) 2007-09-11
CA2592002A1 (fr) 2006-06-29
WO2006066775A1 (fr) 2006-06-29
US20080255099A1 (en) 2008-10-16
EP1827442A1 (fr) 2007-09-05
JP2008525336A (ja) 2008-07-17
ITMI20042477A1 (it) 2005-03-23
IL184114A0 (en) 2007-10-31

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