ZA200604913B - Multilayer tablet - Google Patents
Multilayer tablet Download PDFInfo
- Publication number
- ZA200604913B ZA200604913B ZA200604913A ZA200604913A ZA200604913B ZA 200604913 B ZA200604913 B ZA 200604913B ZA 200604913 A ZA200604913 A ZA 200604913A ZA 200604913 A ZA200604913 A ZA 200604913A ZA 200604913 B ZA200604913 B ZA 200604913B
- Authority
- ZA
- South Africa
- Prior art keywords
- tablet
- layer
- telmisartan
- ramipril
- matrix
- Prior art date
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- HDACQVRGBOVJII-JBDAPHQKSA-N ramipril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](C[C@@H]2CCC[C@@H]21)C(O)=O)CC1=CC=CC=C1 HDACQVRGBOVJII-JBDAPHQKSA-N 0.000 claims description 64
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- JZUFKLXOESDKRF-UHFFFAOYSA-N Chlorothiazide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC2=C1NCNS2(=O)=O JZUFKLXOESDKRF-UHFFFAOYSA-N 0.000 claims description 36
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- 239000008119 colloidal silica Substances 0.000 description 1
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- 229960005168 croscarmellose Drugs 0.000 description 1
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- 238000012864 cross contamination Methods 0.000 description 1
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- 239000013078 crystal Substances 0.000 description 1
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- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000011363 dried mixture Substances 0.000 description 1
- 238000007580 dry-mixing Methods 0.000 description 1
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- 229940009714 erythritol Drugs 0.000 description 1
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- 238000004108 freeze drying Methods 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
- 235000011087 fumaric acid Nutrition 0.000 description 1
- ZZUFCTLCJUWOSV-UHFFFAOYSA-N furosemide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC(C(O)=O)=C1NCC1=CC=CO1 ZZUFCTLCJUWOSV-UHFFFAOYSA-N 0.000 description 1
- 229960003883 furosemide Drugs 0.000 description 1
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- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
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- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000009477 glass transition Effects 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
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- 238000001727 in vivo Methods 0.000 description 1
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- 230000007246 mechanism Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 238000005580 one pot reaction Methods 0.000 description 1
- 230000002669 organ and tissue protective effect Effects 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229960001085 piretanide Drugs 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
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- 230000002265 prevention Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000011253 protective coating Substances 0.000 description 1
- 229940103188 ramipril 2.5 mg Drugs 0.000 description 1
- KEDYTOTWMPBSLG-HILJTLORSA-N ramiprilat Chemical compound C([C@H](N[C@@H](C)C(=O)N1[C@@H](C[C@@H]2CCC[C@@H]21)C(O)=O)C(O)=O)CC1=CC=CC=C1 KEDYTOTWMPBSLG-HILJTLORSA-N 0.000 description 1
- 229960002231 ramiprilat Drugs 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
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- 239000011734 sodium Substances 0.000 description 1
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- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 235000011083 sodium citrates Nutrition 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 229940032147 starch Drugs 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
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- 230000002195 synergetic effect Effects 0.000 description 1
- 239000007916 tablet composition Substances 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 229940101539 telmisartan 40 mg Drugs 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000003451 thiazide diuretic agent Substances 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 229960001288 triamterene Drugs 0.000 description 1
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- 238000009736 wetting Methods 0.000 description 1
- 229960000537 xipamide Drugs 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
- B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
- B30B11/085—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable for multi-layer articles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Mechanical Engineering (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004008804A DE102004008804A1 (de) | 2004-02-20 | 2004-02-20 | Mehrschichttablette |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200604913B true ZA200604913B (en) | 2007-11-28 |
Family
ID=34832975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200604913A ZA200604913B (en) | 2004-02-20 | 2006-06-14 | Multilayer tablet |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20050186274A1 (es) |
| EP (1) | EP1718281A1 (es) |
| JP (1) | JP2007523112A (es) |
| KR (1) | KR20060130671A (es) |
| CN (1) | CN1921840A (es) |
| AR (1) | AR047806A1 (es) |
| AU (1) | AU2005215115A1 (es) |
| BR (1) | BRPI0507887A (es) |
| CA (1) | CA2552902A1 (es) |
| DE (1) | DE102004008804A1 (es) |
| EC (1) | ECSP066779A (es) |
| IL (1) | IL177536A0 (es) |
| MX (1) | MXPA06008225A (es) |
| NO (1) | NO20063997L (es) |
| PE (1) | PE20051127A1 (es) |
| RU (1) | RU2006133453A (es) |
| TW (1) | TW200533389A (es) |
| UY (1) | UY28753A1 (es) |
| WO (1) | WO2005079762A1 (es) |
| ZA (1) | ZA200604913B (es) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080234353A1 (en) * | 2004-03-24 | 2008-09-25 | Reynir Eyjolfsson | Formulations of Ramipril |
| GB0518129D0 (en) * | 2005-09-06 | 2005-10-12 | Arrow Int Ltd | Ramipril formulation |
| US20070098782A1 (en) * | 2005-10-28 | 2007-05-03 | Selamine Limited | Ramipril Formulation |
| GB2431579A (en) * | 2005-10-28 | 2007-05-02 | Arrow Int Ltd | Ramipril formulations |
| US8637078B2 (en) * | 2005-11-24 | 2014-01-28 | Boehringer Ingelheim International Gmbh | Bilayer tablet comprising telmisartan and diuretic |
| CA2642761A1 (en) * | 2006-02-23 | 2007-08-30 | Iomedix Sleep International Srl | Compositions and methods for the induction and maintenance of quality sleep |
| ES2523729T3 (es) | 2006-06-16 | 2014-12-01 | Lek Pharmaceuticals D.D. | Composición farmacéutica que comprende hidroclorotiazida y telmisartán |
| WO2008001184A2 (en) * | 2006-06-26 | 2008-01-03 | Emcure Pharmaceuticals Limited | Solid composition |
| EP1908469A1 (en) * | 2006-10-06 | 2008-04-09 | Boehringer Ingelheim Vetmedica Gmbh | Angiotensin II receptor antagonist for the treatment of systemic diseases in cats |
| WO2008049196A1 (en) * | 2006-10-27 | 2008-05-02 | Iomedix Development International Srl | Composition for improving blood cholesterol levels |
| GB0624084D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril amino acid salts |
| GB0624090D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril amine salts |
| GB0624087D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril combination salt |
| EP1970053A1 (en) * | 2007-03-14 | 2008-09-17 | Boehringer Ingelheim Pharma GmbH & Co. KG | Pharmaceutical composition |
| PL382311A1 (pl) * | 2007-04-27 | 2008-11-10 | Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna | Kompozycja farmaceutyczna o polepszonej stabilności zawierająca inhibitor acetylocholinoesterazy lub farmaceutycznie dopuszczalną jego sól oraz sposób jej wytwarzania |
| US20090060983A1 (en) * | 2007-08-30 | 2009-03-05 | Bunick Frank J | Method And Composition For Making An Orally Disintegrating Dosage Form |
| US20100247649A1 (en) * | 2007-10-30 | 2010-09-30 | Dr. Reddy's Laboratories Ltd. | Pharmaceutical formulations comprising telmisartan and hydrochlorothiazide |
| ES2633449T3 (es) * | 2007-10-31 | 2017-09-21 | Johnson & Johnson Consumer Inc. | Forma de dosis oralmente desintegrable |
| CA2715350C (en) * | 2008-03-19 | 2017-02-14 | Ratiopharm Gmbh | Solid pharmaceutical composition comprising a non-peptide angiotensin ii receptor antagonist and a diuretic |
| US10046081B2 (en) | 2008-04-11 | 2018-08-14 | The Henry M Jackson Foundation For The Advancement Of Military Medicine, Inc. | Electrospun dextran fibers and devices formed therefrom |
| AR076913A1 (es) | 2009-05-20 | 2011-07-20 | Boehringer Ingelheim Vetmed | Solucion farmaceutica bebible de telmisartan. metodo para preparar la solucion |
| US8858210B2 (en) | 2009-09-24 | 2014-10-14 | Mcneil-Ppc, Inc. | Manufacture of variable density dosage forms utilizing radiofrequency energy |
| US8784781B2 (en) | 2009-09-24 | 2014-07-22 | Mcneil-Ppc, Inc. | Manufacture of chewing gum product with radiofrequency |
| RU2479310C2 (ru) * | 2011-02-09 | 2013-04-20 | Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") | Фармацевтическая композиция для лечения артериальной гипертензии и застойной сердечной недостаточности и способ ее получения |
| CN102885789A (zh) * | 2012-04-05 | 2013-01-23 | 常州制药厂有限公司 | 一种治疗高血压的复方制剂的制备方法 |
| US9445971B2 (en) | 2012-05-01 | 2016-09-20 | Johnson & Johnson Consumer Inc. | Method of manufacturing solid dosage form |
| US9511028B2 (en) | 2012-05-01 | 2016-12-06 | Johnson & Johnson Consumer Inc. | Orally disintegrating tablet |
| US9233491B2 (en) | 2012-05-01 | 2016-01-12 | Johnson & Johnson Consumer Inc. | Machine for production of solid dosage forms |
| JP6018420B2 (ja) * | 2012-06-05 | 2016-11-02 | ニプロ株式会社 | アンジオテンシンｉｉ受容体拮抗薬およびサイアザイド系利尿薬を含む医薬組成物 |
| AU2015204763A1 (en) | 2014-01-10 | 2016-07-21 | Johnson & Johnson Consumer Inc. | Process for making tablet using radiofrequency and lossy coated particles |
| EP2979691A1 (en) * | 2014-07-30 | 2016-02-03 | Boehringer Ingelheim International GmbH | Oral disintegrating tablet |
| HK1250627A1 (zh) * | 2015-06-26 | 2019-01-11 | Abbvie Inc. | 用於治疗hcv的固体药物组合物 |
| CA2992722C (en) * | 2015-07-17 | 2023-10-17 | Abbvie Inc. | Solid pharmaceutical compositions for treating hcv |
| AU2016351557A1 (en) | 2015-11-12 | 2018-05-31 | St. Teresa Medical, Inc. | A method of sealing a durotomy |
| US10493026B2 (en) | 2017-03-20 | 2019-12-03 | Johnson & Johnson Consumer Inc. | Process for making tablet using radiofrequency and lossy coated particles |
| US10953128B2 (en) | 2017-11-02 | 2021-03-23 | St. Teresa Medical, Inc. | Fibrin sealant products |
| WO2020109319A1 (en) | 2018-11-27 | 2020-06-04 | Zaklady Farmaceutyczne Polpharma S.A | Pharmaceutical composition comprising ramipril and indapamide |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW483763B (en) * | 1994-09-02 | 2002-04-21 | Astra Ab | Pharmaceutical composition comprising of ramipril and dihydropyridine compound |
| DE4446468A1 (de) * | 1994-12-23 | 1996-06-27 | Basf Ag | Verfahren zur Herstellung von umhüllten Tabletten |
| US6087386A (en) * | 1996-06-24 | 2000-07-11 | Merck & Co., Inc. | Composition of enalapril and losartan |
| WO2000027397A1 (en) * | 1998-11-06 | 2000-05-18 | Glaxo Group Limited | Antihypertensive medicaments containing lacidipine and telmisartan |
| EA200300224A1 (ru) * | 2000-08-22 | 2003-08-28 | Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг | Фармацевтическая комбинация антагонистов ангиотензина ii и ингибиторов асе |
| GB0020691D0 (en) * | 2000-08-22 | 2000-10-11 | Boehringer Ingelheim Pharma | Pharmaceutical combination |
| US20030091630A1 (en) * | 2001-10-25 | 2003-05-15 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data |
| JP2003144528A (ja) * | 2001-11-15 | 2003-05-20 | Fancl Corp | 多層錠及びその製造方法 |
-
2004
- 2004-02-20 DE DE102004008804A patent/DE102004008804A1/de not_active Withdrawn
-
2005
- 2005-02-10 US US11/056,081 patent/US20050186274A1/en not_active Abandoned
- 2005-02-15 MX MXPA06008225A patent/MXPA06008225A/es unknown
- 2005-02-15 KR KR1020067019409A patent/KR20060130671A/ko not_active Withdrawn
- 2005-02-15 RU RU2006133453/15A patent/RU2006133453A/ru not_active Application Discontinuation
- 2005-02-15 WO PCT/EP2005/001498 patent/WO2005079762A1/en not_active Ceased
- 2005-02-15 JP JP2006553509A patent/JP2007523112A/ja active Pending
- 2005-02-15 BR BRPI0507887-3A patent/BRPI0507887A/pt not_active IP Right Cessation
- 2005-02-15 CN CNA2005800052700A patent/CN1921840A/zh active Pending
- 2005-02-15 CA CA002552902A patent/CA2552902A1/en not_active Abandoned
- 2005-02-15 AU AU2005215115A patent/AU2005215115A1/en not_active Abandoned
- 2005-02-15 EP EP05707394A patent/EP1718281A1/en not_active Withdrawn
- 2005-02-17 UY UY28753A patent/UY28753A1/es not_active Application Discontinuation
- 2005-02-18 AR ARP050100579A patent/AR047806A1/es unknown
- 2005-02-18 TW TW094104757A patent/TW200533389A/zh unknown
- 2005-02-18 PE PE2005000192A patent/PE20051127A1/es not_active Application Discontinuation
-
2006
- 2006-06-14 ZA ZA200604913A patent/ZA200604913B/en unknown
- 2006-08-17 IL IL177536A patent/IL177536A0/en unknown
- 2006-08-21 EC EC2006006779A patent/ECSP066779A/es unknown
- 2006-09-06 NO NO20063997A patent/NO20063997L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2552902A1 (en) | 2005-09-01 |
| WO2005079762A1 (en) | 2005-09-01 |
| PE20051127A1 (es) | 2006-01-31 |
| UY28753A1 (es) | 2005-09-30 |
| US20050186274A1 (en) | 2005-08-25 |
| EP1718281A1 (en) | 2006-11-08 |
| RU2006133453A (ru) | 2008-03-27 |
| IL177536A0 (en) | 2006-12-10 |
| AR047806A1 (es) | 2006-02-22 |
| NO20063997L (no) | 2006-11-14 |
| JP2007523112A (ja) | 2007-08-16 |
| TW200533389A (en) | 2005-10-16 |
| ECSP066779A (es) | 2006-12-20 |
| KR20060130671A (ko) | 2006-12-19 |
| MXPA06008225A (es) | 2006-08-31 |
| BRPI0507887A (pt) | 2007-08-07 |
| AU2005215115A1 (en) | 2005-09-01 |
| CN1921840A (zh) | 2007-02-28 |
| DE102004008804A1 (de) | 2005-09-08 |
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