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YU46903A - Derivati difenil-azetidinona,postupak za njihovu proizvodnju lekovi koji sadrže ova jedinjenja i njihova primena - Google Patents

Derivati difenil-azetidinona,postupak za njihovu proizvodnju lekovi koji sadrže ova jedinjenja i njihova primena

Info

Publication number
YU46903A
YU46903A YU46903A YUP46903A YU46903A YU 46903 A YU46903 A YU 46903A YU 46903 A YU46903 A YU 46903A YU P46903 A YUP46903 A YU P46903A YU 46903 A YU46903 A YU 46903A
Authority
YU
Yugoslavia
Prior art keywords
compounds
production
medicaments containing
azetidinone derivatives
diphenyl azetidinone
Prior art date
Application number
YU46903A
Other languages
English (en)
Inventor
Heiner Glombik
Werner Kramer
Stefanie Flohr
Wendelin Frick
Hubert Heuer
Gerhard Jaehne
Andreas Lindenschmidt
Hans-Ludwig Schaefer
Original Assignee
Aventis Pharma Deutschland Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10064402A external-priority patent/DE10064402A1/de
Priority claimed from DE2001154520 external-priority patent/DE10154520A1/de
Application filed by Aventis Pharma Deutschland Gmbh. filed Critical Aventis Pharma Deutschland Gmbh.
Publication of YU46903A publication Critical patent/YU46903A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Pronalazak se odnosi na difenil-azetidinone, postupak za njihovu proizvodnju, lekove koji sasdrže ova jedinjenja i njihovu primenu. Pronalazak se odnosi na jedinjenja formule I, u kojima R1, R2, R3, R4, R5 i R6 imaju navedena značenja, kao i na njihove farmaceutski prihvatljive soli. Jedinjenja su pogodna, na primer, kao hipolipidemijska sredstva.[The invention relates to novel diphenyl azetidinones, to a method for the production thereof, to medicaments containing these compounds, and to their use. The invention concerns compounds of formula (I), wherein R1, R2, R3, R4, R5 and R6 have the cited meanings, and concerns the physiologically compatible salts thereof. The compounds are suited for use e.g. as hypolipidemic drugs.
YU46903A 2000-12-21 2001-12-11 Derivati difenil-azetidinona,postupak za njihovu proizvodnju lekovi koji sadrže ova jedinjenja i njihova primena YU46903A (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10064402A DE10064402A1 (de) 2000-12-21 2000-12-21 Diphenylazetidinonderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
DE2001154520 DE10154520A1 (de) 2001-11-07 2001-11-07 Diphenylazetidinonderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung

Publications (1)

Publication Number Publication Date
YU46903A true YU46903A (sh) 2006-05-25

Family

ID=26008045

Family Applications (1)

Application Number Title Priority Date Filing Date
YU46903A YU46903A (sh) 2000-12-21 2001-12-11 Derivati difenil-azetidinona,postupak za njihovu proizvodnju lekovi koji sadrže ova jedinjenja i njihova primena

Country Status (23)

Country Link
US (1) US6498156B2 (sh)
EP (1) EP1345932B1 (sh)
JP (1) JP2004516293A (sh)
KR (1) KR20030061462A (sh)
CN (1) CN1222522C (sh)
AR (1) AR034282A1 (sh)
AT (1) ATE342899T1 (sh)
AU (2) AU1917302A (sh)
BR (1) BR0116482A (sh)
CA (1) CA2431985A1 (sh)
CZ (1) CZ20031731A3 (sh)
DE (1) DE50111293D1 (sh)
EE (1) EE200300237A (sh)
HR (1) HRP20030499A2 (sh)
HU (1) HUP0401067A2 (sh)
IL (1) IL156552A0 (sh)
MX (1) MXPA03005018A (sh)
NO (1) NO20032733L (sh)
NZ (1) NZ526592A (sh)
PL (1) PL362173A1 (sh)
SK (1) SK7812003A3 (sh)
WO (1) WO2002050068A1 (sh)
YU (1) YU46903A (sh)

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Also Published As

Publication number Publication date
HK1059936A1 (en) 2004-07-23
NO20032733L (no) 2003-08-14
IL156552A0 (en) 2004-01-04
BR0116482A (pt) 2004-02-03
AR034282A1 (es) 2004-02-18
US20020128252A1 (en) 2002-09-12
AU2002219173B2 (en) 2006-06-22
CZ20031731A3 (cs) 2003-09-17
ATE342899T1 (de) 2006-11-15
US6498156B2 (en) 2002-12-24
HUP0401067A2 (hu) 2004-09-28
CA2431985A1 (en) 2002-06-27
WO2002050068A1 (de) 2002-06-27
EE200300237A (et) 2003-08-15
DE50111293D1 (de) 2006-11-30
SK7812003A3 (en) 2004-01-08
PL362173A1 (en) 2004-10-18
MXPA03005018A (es) 2003-09-25
HRP20030499A2 (en) 2005-04-30
KR20030061462A (ko) 2003-07-18
EP1345932B1 (de) 2006-10-18
NO20032733D0 (no) 2003-06-16
JP2004516293A (ja) 2004-06-03
NZ526592A (en) 2004-11-26
AU1917302A (en) 2002-07-01
EP1345932A1 (de) 2003-09-24
CN1481381A (zh) 2004-03-10
CN1222522C (zh) 2005-10-12

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