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YU21801A - Derivati tiazolin kiseline - Google Patents

Derivati tiazolin kiseline

Info

Publication number
YU21801A
YU21801A YU21801A YU21801A YU21801A YU 21801 A YU21801 A YU 21801A YU 21801 A YU21801 A YU 21801A YU 21801 A YU21801 A YU 21801A YU 21801 A YU21801 A YU 21801A
Authority
YU
Yugoslavia
Prior art keywords
acid derivatives
thiazoline acid
thiazoline
diagnosing
pyridyl
Prior art date
Application number
YU21801A
Other languages
English (en)
Inventor
Raymond J. Bergeron Jr.
Original Assignee
University Of Florida Research Foundation Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Florida Research Foundation Inc. filed Critical University Of Florida Research Foundation Inc.
Publication of YU21801A publication Critical patent/YU21801A/sh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/04Chelating agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Game Rules And Presentations Of Slot Machines (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Fenil- i piridil-supstituisani derivati tiazolin kiseline korisni u dijagnosticiranju i tretiranju stanja združenih sa viškom trivalentnih metala kod ljudi i životinja.[Phenyl- and pyridyl-substituted thiazoline acid derivatives useful in diagnosing and treating pathological conditions associated with an excess of trivalent metals in humans and animals.
YU21801A 1998-08-31 1999-08-31 Derivati tiazolin kiseline YU21801A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/144,103 US6083966A (en) 1998-08-31 1998-08-31 Thiazoline acid derivatives

Publications (1)

Publication Number Publication Date
YU21801A true YU21801A (sh) 2005-07-19

Family

ID=22507049

Family Applications (1)

Application Number Title Priority Date Filing Date
YU21801A YU21801A (sh) 1998-08-31 1999-08-31 Derivati tiazolin kiseline

Country Status (23)

Country Link
US (9) US6083966A (sh)
EP (1) EP1109795B1 (sh)
JP (3) JP4817498B2 (sh)
KR (1) KR20010074907A (sh)
CN (1) CN100455574C (sh)
AT (1) ATE317392T1 (sh)
AU (1) AU759851B2 (sh)
BR (1) BR9913441B1 (sh)
CA (1) CA2342210C (sh)
CZ (1) CZ2001711A3 (sh)
DE (1) DE69929807T2 (sh)
EA (1) EA200100261A1 (sh)
ES (1) ES2260933T3 (sh)
HU (1) HUP0103165A3 (sh)
IL (2) IL141611A0 (sh)
NO (1) NO321028B1 (sh)
NZ (1) NZ509899A (sh)
PL (1) PL346852A1 (sh)
PT (1) PT1109795E (sh)
TR (1) TR200100541T2 (sh)
UA (1) UA57161C2 (sh)
WO (1) WO2000012493A1 (sh)
YU (1) YU21801A (sh)

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US6083966A (en) * 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
WO2000016763A2 (en) * 1998-09-21 2000-03-30 University Of Florida Research Foundation, Inc. Antimalarial agents
EP1488791A3 (en) * 1998-09-21 2005-04-06 University Of Florida Research Foundation, Inc. Antimalarial agents
US6806363B1 (en) * 1999-04-16 2004-10-19 Mayo Foundation For Medical Education & Research Cobalamin conjugates useful as antitumor agents
MXPA02003772A (es) 1999-10-15 2005-04-28 Mayo Foundation Conjugados de cobalamina, utiles como agentes para obtencion de imagen y como agentes terapeuticos.
US6689788B1 (en) * 2000-08-25 2004-02-10 University Of Florida Method and composition for treatment of inflammatory bowel disease
TWI228512B (en) * 2000-10-25 2005-03-01 Mayo Foundation Transcobalamin binding conjugates useful for treating abnormal cellular proliferation
US6846958B2 (en) 2002-05-15 2005-01-25 Genzyme Corporation Synthesis of benzimidate from benzoic acid
WO2004017959A2 (en) * 2002-08-22 2004-03-04 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
US20040044220A1 (en) * 2002-08-22 2004-03-04 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
EP1548013A4 (en) * 2002-10-01 2006-07-12 Kaneka Corp PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE ALPHA-SUBSTITUTED CYSTEINE OR SALT THEREOF, INTERMEDIATE THEREFOR AND PROCESS FOR PRODUCTION THEREOF
US20040185028A1 (en) * 2003-03-19 2004-09-23 Zhenze Hu Antimicrobial compositions containing ethanolamine buffer and biguanide disinfectant
WO2005034949A1 (en) * 2003-09-09 2005-04-21 University Of Florida Desferrithiocin derivatives and their use as iron chelators
ATE400300T1 (de) * 2003-09-09 2008-07-15 Univ Florida Polyamin-metallchelatbildner-konjugate
WO2005055931A2 (en) * 2003-12-03 2005-06-23 University Of Medicine And Dentistry Of New Jersey Method of preventing survival of retrovirally cells and of inhibiting formation of infectious retroviruses
WO2005075475A1 (ja) * 2004-02-04 2005-08-18 Shionogi & Co., Ltd. Hivインテグラーゼ阻害活性を有するナフチリジン誘導体
EP1866296B1 (en) 2005-04-04 2016-11-02 University of Florida Research Foundation, Inc. Desferrithiocin polyether analogues
US7365371B2 (en) 2005-08-04 2008-04-29 Cree, Inc. Packages for semiconductor light emitting devices utilizing dispensed encapsulants
AU2007351826A1 (en) * 2006-12-12 2008-10-30 University Of Florida Research Foundation, Inc. Desferrithiocin analogue actinide decorporation agents
NZ579994A (en) 2007-03-15 2011-09-30 Univ Florida Desferrithiocin polyether analogues useful in the treatment of pathological conditions responsive to chelation or sequestration of trivalent metal
CN103435569B (zh) 2008-07-14 2015-08-19 法罗肯生物科学公司 作为金属螯合剂的脱氮杂去铁硫辛聚醚类似物的新型盐和多晶型物
JP2013525495A (ja) 2010-05-04 2013-06-20 シャイアー・リミテッド・ライアビリティ・カンパニー 金属キレート化剤としてのデスアザデスフェリチオシン類似体
EP2711419A4 (en) * 2011-05-19 2014-12-31 Univ Tokushima CELL DIFFERENTIATION INDUCTOR AND METHOD OF DIFFERENTIATION INDUCTION
KR102111176B1 (ko) 2011-12-16 2020-05-15 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 4'-데스페리티오신 유사체의 용도
JP6353751B2 (ja) * 2013-09-25 2018-07-04 国立大学法人電気通信大学 新規複素環式化合物及びその塩、並びに、発光基質組成物
AU2014352780A1 (en) * 2013-11-22 2016-06-09 University Of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof
WO2016176343A1 (en) 2015-04-27 2016-11-03 University Of Florida Research Foundation, Incorporated Metabolically programmed metal chelators and uses thereof

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WO2005034949A1 (en) 2003-09-09 2005-04-21 University Of Florida Desferrithiocin derivatives and their use as iron chelators
ATE400300T1 (de) 2003-09-09 2008-07-15 Univ Florida Polyamin-metallchelatbildner-konjugate
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EP1866296B1 (en) 2005-04-04 2016-11-02 University of Florida Research Foundation, Inc. Desferrithiocin polyether analogues
AU2007351826A1 (en) * 2006-12-12 2008-10-30 University Of Florida Research Foundation, Inc. Desferrithiocin analogue actinide decorporation agents
NZ579994A (en) * 2007-03-15 2011-09-30 Univ Florida Desferrithiocin polyether analogues useful in the treatment of pathological conditions responsive to chelation or sequestration of trivalent metal

Also Published As

Publication number Publication date
US6525080B1 (en) 2003-02-25
NO20011003L (no) 2001-02-27
CZ2001711A3 (cs) 2001-09-12
NO20011003D0 (no) 2001-02-27
US7531563B2 (en) 2009-05-12
ATE317392T1 (de) 2006-02-15
WO2000012493A1 (en) 2000-03-09
US7126004B2 (en) 2006-10-24
JP2002523500A (ja) 2002-07-30
KR20010074907A (ko) 2001-08-09
DE69929807D1 (de) 2006-04-20
US6559315B1 (en) 2003-05-06
US8008502B2 (en) 2011-08-30
AU5789799A (en) 2000-03-21
PL346852A1 (en) 2002-03-11
BR9913441B1 (pt) 2013-10-29
US6521652B1 (en) 2003-02-18
US6083966A (en) 2000-07-04
UA57161C2 (uk) 2003-06-16
PT1109795E (pt) 2006-06-30
CN100455574C (zh) 2009-01-28
JP4817498B2 (ja) 2011-11-16
TR200100541T2 (tr) 2001-11-21
CA2342210C (en) 2009-03-10
USRE39132E1 (en) 2006-06-13
EP1109795A4 (en) 2002-01-16
CA2342210A1 (en) 2000-03-09
JP2014065730A (ja) 2014-04-17
US20070238767A1 (en) 2007-10-11
WO2000012493A9 (en) 2002-04-11
EP1109795B1 (en) 2006-02-08
EP1109795A1 (en) 2001-06-27
US20030236417A1 (en) 2003-12-25
IL141611A0 (en) 2002-03-10
EA200100261A1 (ru) 2001-10-22
US20100094016A1 (en) 2010-04-15
JP2011178797A (ja) 2011-09-15
ES2260933T3 (es) 2006-11-01
HK1035720A1 (en) 2003-04-24
HUP0103165A3 (en) 2003-03-28
CN1313856A (zh) 2001-09-19
BR9913441A (pt) 2001-10-23
JP5520875B2 (ja) 2014-06-11
NO321028B1 (no) 2006-02-27
IL141611A (en) 2006-12-31
HUP0103165A2 (hu) 2002-01-28
AU759851B2 (en) 2003-05-01
US20050033057A1 (en) 2005-02-10
NZ509899A (en) 2003-12-19
DE69929807T2 (de) 2006-11-02

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