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BR9913441B1 - "composto derivado do ácido tiazolínico e uso de um composto derivado do ácido tiazolínico" - Google Patents

"composto derivado do ácido tiazolínico e uso de um composto derivado do ácido tiazolínico"

Info

Publication number
BR9913441B1
BR9913441B1 BRPI9913441-1B1A BR9913441A BR9913441B1 BR 9913441 B1 BR9913441 B1 BR 9913441B1 BR 9913441 A BR9913441 A BR 9913441A BR 9913441 B1 BR9913441 B1 BR 9913441B1
Authority
BR
Brazil
Prior art keywords
tiazolinic
acid derivative
derivative compound
compound
diagnosing
Prior art date
Application number
BRPI9913441-1B1A
Other languages
English (en)
Other versions
BR9913441A (pt
Inventor
Jr Raymond J Bergeron
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BR9913441A publication Critical patent/BR9913441A/pt
Publication of BR9913441B1 publication Critical patent/BR9913441B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/04Chelating agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Game Rules And Presentations Of Slot Machines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)
BRPI9913441-1B1A 1998-08-31 1999-08-31 "composto derivado do ácido tiazolínico e uso de um composto derivado do ácido tiazolínico" BR9913441B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/144,103 US6083966A (en) 1998-08-31 1998-08-31 Thiazoline acid derivatives
PCT/US1999/019691 WO2000012493A1 (en) 1998-08-31 1999-08-31 Thiazoline acid derivatives

Publications (2)

Publication Number Publication Date
BR9913441A BR9913441A (pt) 2001-10-23
BR9913441B1 true BR9913441B1 (pt) 2013-10-29

Family

ID=22507049

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9913441-1B1A BR9913441B1 (pt) 1998-08-31 1999-08-31 "composto derivado do ácido tiazolínico e uso de um composto derivado do ácido tiazolínico"

Country Status (23)

Country Link
US (9) US6083966A (pt)
EP (1) EP1109795B1 (pt)
JP (3) JP4817498B2 (pt)
KR (1) KR20010074907A (pt)
CN (1) CN100455574C (pt)
AT (1) ATE317392T1 (pt)
AU (1) AU759851B2 (pt)
BR (1) BR9913441B1 (pt)
CA (1) CA2342210C (pt)
CZ (1) CZ2001711A3 (pt)
DE (1) DE69929807T2 (pt)
EA (1) EA200100261A1 (pt)
ES (1) ES2260933T3 (pt)
HU (1) HUP0103165A3 (pt)
IL (2) IL141611A0 (pt)
NO (1) NO321028B1 (pt)
NZ (1) NZ509899A (pt)
PL (1) PL346852A1 (pt)
PT (1) PT1109795E (pt)
TR (1) TR200100541T2 (pt)
UA (1) UA57161C2 (pt)
WO (1) WO2000012493A1 (pt)
YU (1) YU21801A (pt)

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US6083966A (en) * 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
EP1488791A3 (en) * 1998-09-21 2005-04-06 University Of Florida Research Foundation, Inc. Antimalarial agents
CN1585639A (zh) * 1998-09-21 2005-02-23 佛罗里达大学研究基金会 抗疟疾制剂
US6806363B1 (en) * 1999-04-16 2004-10-19 Mayo Foundation For Medical Education & Research Cobalamin conjugates useful as antitumor agents
EP1239887A1 (en) 1999-10-15 2002-09-18 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
US6689788B1 (en) * 2000-08-25 2004-02-10 University Of Florida Method and composition for treatment of inflammatory bowel disease
TWI228512B (en) * 2000-10-25 2005-03-01 Mayo Foundation Transcobalamin binding conjugates useful for treating abnormal cellular proliferation
US6794515B2 (en) * 2002-05-15 2004-09-21 Genzyme Corporation Synthesis of 2-alkylcysteine via substituted thiazoline amide
US20040044220A1 (en) * 2002-08-22 2004-03-04 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
US20040132789A1 (en) * 2002-08-22 2004-07-08 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
WO2004031163A1 (ja) * 2002-10-01 2004-04-15 Kaneka Corporation 光学活性α−置換システインまたはその塩の製造方法並びにその合成中間体及びその製造方法
US20040185028A1 (en) * 2003-03-19 2004-09-23 Zhenze Hu Antimicrobial compositions containing ethanolamine buffer and biguanide disinfectant
AU2004270261B2 (en) * 2003-09-09 2008-12-04 University Of Florida Research Foundation, Inc. Polyamine-metal chelator conjugates
AU2003270473A1 (en) * 2003-09-09 2005-04-27 University Of Florida Desferrithiocin derivatives and their use as iron chelators
EP1694325A4 (en) * 2003-12-03 2009-03-25 Univ New Jersey Med Method of preventing survival of retrovirally cells and of inhibiting formation of infectious retroviruses
US7919623B2 (en) * 2004-02-04 2011-04-05 Shionogi & Co., Ltd. Naphthyridine derivatives having inhibitory activity against HIV integrase
BRPI0610644B8 (pt) * 2005-04-04 2021-05-25 Univ Florida composto e composição farmacêutica que compreende tal composto e um veículo ou diluente farmaceuticamente aceitável.
US7365371B2 (en) 2005-08-04 2008-04-29 Cree, Inc. Packages for semiconductor light emitting devices utilizing dispensed encapsulants
US20100137346A1 (en) * 2006-12-12 2010-06-03 University Of Florida Research Foundation, Inc. Desferrithiocin analogue actinide decorporation agents
CA2680592C (en) * 2007-03-15 2016-07-05 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues and uses thereof in treating pathological conditions
CA2728636A1 (en) * 2008-07-14 2010-01-21 Ferrokin Biosciences, Inc. Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents
CA2798082A1 (en) 2010-05-04 2011-11-10 Shire Llc Desazadesferrothiocin analogues as metal chelation agents
WO2012157612A1 (ja) * 2011-05-19 2012-11-22 国立大学法人徳島大学 細胞分化誘導剤および分化誘導方法
ES2761200T3 (es) 2011-12-16 2020-05-19 Univ Florida Usos de análogos de 4'-desferritiocina
JP6353751B2 (ja) * 2013-09-25 2018-07-04 国立大学法人電気通信大学 新規複素環式化合物及びその塩、並びに、発光基質組成物
CA2930966A1 (en) 2013-11-22 2015-05-28 University Of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof
JP2018515475A (ja) 2015-04-27 2018-06-14 ユニバーシティー オブ フロリダ リサーチ ファンデーション, インク. 代謝的にプログラムされた金属キレーターおよびその使用

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BRPI0610644B8 (pt) 2005-04-04 2021-05-25 Univ Florida composto e composição farmacêutica que compreende tal composto e um veículo ou diluente farmaceuticamente aceitável.
US20100137346A1 (en) 2006-12-12 2010-06-03 University Of Florida Research Foundation, Inc. Desferrithiocin analogue actinide decorporation agents
CA2680592C (en) 2007-03-15 2016-07-05 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues and uses thereof in treating pathological conditions

Also Published As

Publication number Publication date
US7531563B2 (en) 2009-05-12
AU759851B2 (en) 2003-05-01
US20100094016A1 (en) 2010-04-15
US6083966A (en) 2000-07-04
YU21801A (sh) 2005-07-19
EA200100261A1 (ru) 2001-10-22
DE69929807D1 (de) 2006-04-20
BR9913441A (pt) 2001-10-23
WO2000012493A1 (en) 2000-03-09
DE69929807T2 (de) 2006-11-02
IL141611A (en) 2006-12-31
US7126004B2 (en) 2006-10-24
JP5520875B2 (ja) 2014-06-11
WO2000012493A9 (en) 2002-04-11
JP4817498B2 (ja) 2011-11-16
USRE39132E1 (en) 2006-06-13
HK1035720A1 (en) 2003-04-24
HUP0103165A2 (hu) 2002-01-28
TR200100541T2 (tr) 2001-11-21
AU5789799A (en) 2000-03-21
JP2002523500A (ja) 2002-07-30
NO20011003D0 (no) 2001-02-27
CN100455574C (zh) 2009-01-28
CA2342210A1 (en) 2000-03-09
US6525080B1 (en) 2003-02-25
NO20011003L (no) 2001-02-27
US6521652B1 (en) 2003-02-18
NO321028B1 (no) 2006-02-27
EP1109795A1 (en) 2001-06-27
HUP0103165A3 (en) 2003-03-28
CZ2001711A3 (cs) 2001-09-12
UA57161C2 (uk) 2003-06-16
CA2342210C (en) 2009-03-10
PL346852A1 (en) 2002-03-11
JP2011178797A (ja) 2011-09-15
PT1109795E (pt) 2006-06-30
US20070238767A1 (en) 2007-10-11
ES2260933T3 (es) 2006-11-01
NZ509899A (en) 2003-12-19
IL141611A0 (en) 2002-03-10
US20030236417A1 (en) 2003-12-25
US20050033057A1 (en) 2005-02-10
EP1109795B1 (en) 2006-02-08
JP2014065730A (ja) 2014-04-17
US6559315B1 (en) 2003-05-06
US8008502B2 (en) 2011-08-30
EP1109795A4 (en) 2002-01-16
ATE317392T1 (de) 2006-02-15
KR20010074907A (ko) 2001-08-09
CN1313856A (zh) 2001-09-19

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