DK1000034T3 - Substituerede 6-alkylphenanthridiner - Google Patents
Substituerede 6-alkylphenanthridinerInfo
- Publication number
- DK1000034T3 DK1000034T3 DK98942571T DK98942571T DK1000034T3 DK 1000034 T3 DK1000034 T3 DK 1000034T3 DK 98942571 T DK98942571 T DK 98942571T DK 98942571 T DK98942571 T DK 98942571T DK 1000034 T3 DK1000034 T3 DK 1000034T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkylphenanthridines
- substituted
- ipharmaceutically
- compositions
- compounds
- Prior art date
Links
- 229940099471 Phosphodiesterase inhibitor Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002571 phosphodiesterase inhibitor Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
- C07D221/12—Phenanthridines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Otolaryngology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97112794 | 1997-07-25 | ||
| PCT/EP1998/004476 WO1999005112A1 (en) | 1997-07-25 | 1998-07-18 | Substituted 6-alkylphenanthridines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1000034T3 true DK1000034T3 (da) | 2003-01-27 |
Family
ID=8227118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98942571T DK1000034T3 (da) | 1997-07-25 | 1998-07-18 | Substituerede 6-alkylphenanthridiner |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6214839B1 (da) |
| EP (1) | EP1000034B1 (da) |
| JP (1) | JP2001510826A (da) |
| AT (1) | ATE224372T1 (da) |
| AU (1) | AU9066498A (da) |
| DE (1) | DE69808099T2 (da) |
| DK (1) | DK1000034T3 (da) |
| ES (1) | ES2184318T3 (da) |
| PT (1) | PT1000034E (da) |
| SI (1) | SI1000034T1 (da) |
| WO (1) | WO1999005112A1 (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR200909479T2 (tr) | 1999-08-21 | 2012-02-21 | Nycomed Gmbh | Sinerjistik kombinasyon. |
| WO2002005616A1 (en) * | 2000-07-14 | 2002-01-24 | Altana Pharma Ag | Novel 6-phenylphenanthridines |
| US6884802B2 (en) | 2000-07-14 | 2005-04-26 | Altana Pharma Ag | 6-heteroarylphenanthridines |
| CA2496459C (en) | 2002-08-29 | 2013-06-25 | Altana Pharma Ag | 3-hydroxy-6-phenylphenanthridines as pde-4 inhibitors |
| ES2279215T3 (es) | 2002-08-29 | 2007-08-16 | Altana Pharma Ag | 2-hidroxi-6-fenilfenantridinas como inhibidores de pde-4. |
| MXPA05010373A (es) | 2003-04-01 | 2005-12-05 | Applied Research Systems | Inhibidores de fosfodiesterasas en infertilidad. |
| ES2400823T3 (es) | 2004-02-18 | 2013-04-12 | Takeda Gmbh | Nuevas hidroxi-6-fenilfenantridinas sustituidas con guanidinilo como inhibidores eficaces de fosfodiesterasa (PDE) 4 |
| AR049419A1 (es) * | 2004-03-03 | 2006-08-02 | Altana Pharma Ag | Hidroxi-6-fenilfenantridinas sustituidas con heterociclilo |
| CN104803974A (zh) * | 2004-03-03 | 2015-07-29 | 塔科达有限责任公司 | 新的羟基-6-杂芳基菲啶及其作为pde4抑制剂的用途 |
| KR20060130697A (ko) * | 2004-03-10 | 2006-12-19 | 알타나 파마 아게 | 신규한 아미도-치환 히드록시-6-페닐페난트리딘 및 ｐｄｅ4억제제로서의 이의 용도 |
| WO2006026725A2 (en) | 2004-08-31 | 2006-03-09 | C.R. Bard, Inc. | Self-sealing ptfe graft with kink resistance |
| KR101421914B1 (ko) | 2005-03-02 | 2014-07-22 | 다케다 게엠베하 | 6-헤테로시클릴 치환된 헥사히드로페난트리딘 유도체의 신규한 염 |
| US20110076315A1 (en) * | 2005-06-08 | 2011-03-31 | C.R Bard, Inc. | Grafts and Stents Having Inorganic Bio-Compatible Calcium Salt |
| WO2007001472A2 (en) | 2005-06-17 | 2007-01-04 | C. R. Bard, Inc. | Vascular graft with kink resistance after clamping |
| EP1945138A4 (en) | 2005-11-09 | 2010-02-10 | Bard Inc C R | IMPLANTS AND STENT PROSTHESES |
| WO2008063780A2 (en) | 2006-10-12 | 2008-05-29 | C.R. Bard Inc. | Vascular grafts with multiple channels and methods for making |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1199773B (de) * | 1962-02-23 | 1965-09-02 | Hoffmann La Roche | Verfahren zur Herstellung von 6-Methyl-8, 9-methylendioxy-1, 2, 3, 4, 4a, 5, 6, 10b-octahydrophenanthridin und dessen Salzen |
| US3243438A (en) | 1962-02-23 | 1966-03-29 | Hoffmann La Roche | Octahydro phenanthridine compounds |
| US4309545A (en) * | 1980-07-28 | 1982-01-05 | Pfizer Inc. | Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof |
-
1998
- 1998-07-18 ES ES98942571T patent/ES2184318T3/es not_active Expired - Lifetime
- 1998-07-18 US US09/462,507 patent/US6214839B1/en not_active Expired - Fee Related
- 1998-07-18 JP JP2000504111A patent/JP2001510826A/ja not_active Withdrawn
- 1998-07-18 EP EP98942571A patent/EP1000034B1/en not_active Expired - Lifetime
- 1998-07-18 PT PT98942571T patent/PT1000034E/pt unknown
- 1998-07-18 SI SI9830300T patent/SI1000034T1/xx unknown
- 1998-07-18 DE DE69808099T patent/DE69808099T2/de not_active Expired - Fee Related
- 1998-07-18 WO PCT/EP1998/004476 patent/WO1999005112A1/en not_active Ceased
- 1998-07-18 DK DK98942571T patent/DK1000034T3/da active
- 1998-07-18 AU AU90664/98A patent/AU9066498A/en not_active Abandoned
- 1998-07-18 AT AT98942571T patent/ATE224372T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US6214839B1 (en) | 2001-04-10 |
| ATE224372T1 (de) | 2002-10-15 |
| EP1000034B1 (en) | 2002-09-18 |
| ES2184318T3 (es) | 2003-04-01 |
| EP1000034A1 (en) | 2000-05-17 |
| AU9066498A (en) | 1999-02-16 |
| DE69808099D1 (de) | 2002-10-24 |
| PT1000034E (pt) | 2003-02-28 |
| WO1999005112A1 (en) | 1999-02-04 |
| DE69808099T2 (de) | 2003-05-15 |
| SI1000034T1 (en) | 2003-04-30 |
| JP2001510826A (ja) | 2001-08-07 |
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