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WO2025133098A3 - Procédés de fabrication de formes cristallines de sels de (s)-n-(3-amino-1-(hydroxyamino)-3-méthyl-1-oxobutan-2-yl)-4-((4-(((2-méthoxyéthyl)amino)méthyl)phényl)éthynyl)benzamide - Google Patents

Procédés de fabrication de formes cristallines de sels de (s)-n-(3-amino-1-(hydroxyamino)-3-méthyl-1-oxobutan-2-yl)-4-((4-(((2-méthoxyéthyl)amino)méthyl)phényl)éthynyl)benzamide

Info

Publication number
WO2025133098A3
WO2025133098A3 PCT/EP2024/087865 EP2024087865W WO2025133098A3 WO 2025133098 A3 WO2025133098 A3 WO 2025133098A3 EP 2024087865 W EP2024087865 W EP 2024087865W WO 2025133098 A3 WO2025133098 A3 WO 2025133098A3
Authority
WO
WIPO (PCT)
Prior art keywords
amino
methyl
oxobutan
hydroxyamino
ethynyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/EP2024/087865
Other languages
English (en)
Other versions
WO2025133098A2 (fr
Inventor
Christophe Pierre Alain Chassaing
Daniel Salanta
Thorsten Meyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intervet International BV
Intervet Inc
Original Assignee
Intervet International BV
Intervet Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet International BV, Intervet Inc filed Critical Intervet International BV
Publication of WO2025133098A2 publication Critical patent/WO2025133098A2/fr
Publication of WO2025133098A3 publication Critical patent/WO2025133098A3/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne des procédés de fabrication de formes cristallines de sels de (S)-N-(3-amino-1-(hydroxyamino)-3-méthyl-1-oxobutan-2-yl)-4-((4-(((2- méthoxyéthyl)amino)méthyl)phényl) éthynyl)benzamide.
PCT/EP2024/087865 2023-12-21 2024-12-20 Procédés de fabrication de formes cristallines de sels de (s)-n-(3-amino-1-(hydroxyamino)-3-méthyl-1-oxobutan-2-yl)-4-((4-(((2-méthoxyéthyl)amino)méthyl)phényl)éthynyl)benzamide Pending WO2025133098A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP23218942.3 2023-12-21
EP23218942 2023-12-21

Publications (2)

Publication Number Publication Date
WO2025133098A2 WO2025133098A2 (fr) 2025-06-26
WO2025133098A3 true WO2025133098A3 (fr) 2025-08-07

Family

ID=89224710

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2024/087865 Pending WO2025133098A2 (fr) 2023-12-21 2024-12-20 Procédés de fabrication de formes cristallines de sels de (s)-n-(3-amino-1-(hydroxyamino)-3-méthyl-1-oxobutan-2-yl)-4-((4-(((2-méthoxyéthyl)amino)méthyl)phényl)éthynyl)benzamide

Country Status (1)

Country Link
WO (1) WO2025133098A2 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013170030A1 (fr) * 2012-05-09 2013-11-14 Achaogen, Inc. Agents antibactériens
WO2018115432A2 (fr) * 2016-12-23 2018-06-28 Intervet International B.V. Composés pour le traitement d'une maladie respiratoire bovine ou porcine
WO2023118558A1 (fr) * 2021-12-24 2023-06-29 Intervet International B.V. Procédé de préparation de dérivés d'hydroxylamine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR128074A1 (es) 2021-12-24 2024-03-20 Intervet Int Bv Composición farmacéutica inyectable para el tratamiento de enfermedades respiratorias en animales

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013170030A1 (fr) * 2012-05-09 2013-11-14 Achaogen, Inc. Agents antibactériens
WO2018115432A2 (fr) * 2016-12-23 2018-06-28 Intervet International B.V. Composés pour le traitement d'une maladie respiratoire bovine ou porcine
WO2023118558A1 (fr) * 2021-12-24 2023-06-29 Intervet International B.V. Procédé de préparation de dérivés d'hydroxylamine

Also Published As

Publication number Publication date
WO2025133098A2 (fr) 2025-06-26

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