[go: up one dir, main page]

WO2022006865A1 - Appareil et système de neurostimulation ultrasonore pouvant être porté sur soi - Google Patents

Appareil et système de neurostimulation ultrasonore pouvant être porté sur soi Download PDF

Info

Publication number
WO2022006865A1
WO2022006865A1 PCT/CN2020/101386 CN2020101386W WO2022006865A1 WO 2022006865 A1 WO2022006865 A1 WO 2022006865A1 CN 2020101386 W CN2020101386 W CN 2020101386W WO 2022006865 A1 WO2022006865 A1 WO 2022006865A1
Authority
WO
WIPO (PCT)
Prior art keywords
ultrasonic
wearable
nerve stimulation
ultrasonic transducer
stimulation device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2020/101386
Other languages
English (en)
Chinese (zh)
Inventor
郑海荣
牛丽丽
钟永盛
孟龙
邹俊杰
黄小伟
易沙沙
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Institute of Advanced Technology of CAS
Original Assignee
Shenzhen Institute of Advanced Technology of CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Institute of Advanced Technology of CAS filed Critical Shenzhen Institute of Advanced Technology of CAS
Priority to PCT/CN2020/101386 priority Critical patent/WO2022006865A1/fr
Publication of WO2022006865A1 publication Critical patent/WO2022006865A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy

Definitions

  • the application belongs to the technical field of medical equipment, and in particular relates to a wearable ultrasonic nerve stimulation device and system.
  • Physical brain stimulation neuromodulation technology provides an effective clinical treatment method for patients with brain function diseases.
  • Medical ultrasound is a non-invasive diagnosis and treatment technology that can form a focal point in the human body that is an oblong shape. This feature also enables him to obtain good spatial accuracy and target specific areas of tissue. Medical ultrasound can be divided into high-intensity focused ultrasound and low-intensity focused ultrasound. High-intensity focused ultrasound is a treatment method that directly damages the lesion, while low-intensity focused ultrasound also plays an important role in the field of neuromodulation.
  • the examiner needs to hold the ultrasonic transducer, which is a waste of manpower and inconvenient to operate, and the examinee needs to lie on the bed more often, unable to move freely and it is difficult to match the operation of the ultrasonic transducer. position, which can easily lead to large operating errors.
  • the embodiments of the present application provide a wearable ultrasonic nerve stimulation device and system to at least solve the problems that the current ultrasonic transducer is inconvenient to operate and difficult to match with the examinee, which easily leads to operation errors.
  • a wearable ultrasonic nerve stimulation device including: a wearable component; an ultrasonic transducer for outputting an ultrasonic nerve stimulation signal; and a connection structure for connecting the wearable component and all The ultrasonic transducer is used to adjust the relative position between the wearable component and the ultrasonic transducer.
  • a wearable ultrasonic nerve stimulation system comprising: the above-mentioned wearable ultrasonic nerve stimulation device; a display; wherein, the ultrasonic transducer in the wearable ultrasonic nerve stimulation device The device is used to collect neural image information; the display is used to display the neural image information.
  • the wearer can wear the wearable component like clothes to receive the neurostimulation operation, the wearer can move freely to obtain a better ultrasonic medical experience, and the wearable component and the ultrasonic exchange
  • the transducers are connected by a connection structure, and the relative position between the wearable component and the ultrasonic transducer can be adjusted through the connection structure, so that the ultrasonic transducer has a large operating position range, and the operation error can be reduced.
  • FIG. 1 shows a schematic structural diagram of an example of a wearable ultrasonic nerve stimulation device according to an embodiment of the present application
  • FIG. 2 shows a schematic structural diagram of an example of a wearable ultrasonic nerve stimulation device according to an embodiment of the present application
  • FIG. 3 shows a structural block diagram of an example of a wearable ultrasonic nerve stimulation system according to an embodiment of the present application.
  • ultrasound technology is used to stimulate human tissue, and several effects are produced to cause changes in diseased tissue, so as to achieve the purpose of treatment.
  • These ultrasonic effects are mainly thermal effects, mechanical effects and cavitation effects.
  • part of the sound energy is absorbed by the medium due to the viscosity and thermal conductivity of the medium during the propagation of the ultrasonic wave, and the result is converted into heat energy and causes the local temperature to rise.
  • certain reactions occur, such as vasodilation, accelerated blood circulation, and increased tissue metabolism, thereby promoting the absorption and dissipation of pathological products.
  • the mechanical effect of particle vibration in the medium causes acceleration, rotation, and rushing vibrations of some fine tissues, thus playing a massage role and enhancing the semi-permeable membrane. It also has a good effect on the material exchange of cells and tissue nutrition.
  • cavitation In the stimulation mechanism of the cavitation effect, during the propagation of ultrasonic waves, when sufficient ultrasonic intensity encounters some liquid tissues in the human body, cavitation will be generated, which can generate high-intensity micro shock waves, which can change or destroy lesions tissue for therapeutic purposes.
  • the wearable ultrasonic nerve stimulation device and system disclosed in the embodiments of the present application mainly relate to the structure or connection relationship of each component in the wearable ultrasonic nerve stimulation device or system, and various effects can be used.
  • the stimulatory mechanism of action should not be limited here.
  • the term “if” may be contextually interpreted as “when” or “once” or “in response to determining” or “in response to detecting” .
  • the phrases “if it is determined” or “if the [described condition or event] is detected” may be interpreted, depending on the context, to mean “once it is determined” or “in response to the determination” or “once the [described condition or event] is detected. ]” or “in response to detection of the [described condition or event]”.
  • the mobile terminals described in the embodiments of the present application include, but are not limited to, other portable devices such as mobile phones, laptop computers or tablet computers with touch-sensitive surfaces (eg, touch screen displays and/or touch pads).
  • other portable devices such as mobile phones, laptop computers or tablet computers with touch-sensitive surfaces (eg, touch screen displays and/or touch pads).
  • touch-sensitive surfaces eg, touch screen displays and/or touch pads.
  • the above-described devices are not portable communication devices, but rather desktop computers with touch-sensitive surfaces (eg, touch screen displays and/or touch pads).
  • FIG. 1 shows a schematic structural diagram of an example of a wearable ultrasonic nerve stimulation device according to an embodiment of the present application.
  • the wearable ultrasonic nerve stimulation device 100 includes a wearable component 110 , a connecting structure 120 and an ultrasonic transducer 130 .
  • the wearable part 110 can be designed in the style of a top (or vest) to facilitate wearing by the wearer, for example, the wearable part 110 is provided with a neck hole 2 and a shoulder hole 3, so that the neck hole 2 is used for The wearer's neck passes through, and the shoulder holes 3 are used for the wearer's upper limbs to pass through. It should be understood that the wearable component 110 can also be designed in other styles, for example, the wearable component 110 can also be designed in a pants or backpack style, and so on.
  • the ultrasonic transducer 130 may output an ultrasonic nerve stimulation signal, and the working parameters (eg, power, frequency, waveform, etc.) of the ultrasonic nerve stimulation signal may be preset, and may be a variety of ultrasonic nerve stimulation signals. It should be understood that an ultrasonic transducer (also referred to as an ultrasonic probe) is an important part of medical ultrasonic equipment, which can perform conversion between electrical and mechanical energy.
  • the ultrasonic transducer 130 may integrate an ultrasonic generating function, so that the ultrasonic transducer 130 can independently and autonomously generate a driving signal (electrical signal) and output a corresponding ultrasonic nerve stimulation signal (acoustic signal). ).
  • the ultrasonic transducer 130 may be electrically connected with an ultrasonic generator, and the ultrasonic generator (also referred to as an ultrasonic driving power source), which can convert commercial power into an ultrasonic transducer Matching high-frequency alternating current signals (for example, ultrasonic electrical signals of various parameter types) to drive the ultrasonic transducer to work.
  • the ultrasonic transducer can output a corresponding ultrasonic nerve stimulation signal (acoustic signal) according to the driving signal generated by the ultrasonic generator.
  • connection structure 120 connects the wearable part 110 and the ultrasonic transducer 130 , and the relative position between the wearable part 110 and the ultrasonic transducer 130 can be adjusted through the connection structure 120 . It should be understood that with regard to the adjustment direction of the relative position, it may be limited or diverse (eg, it may be adjusted at any angle with respect to the wearable component 110 ).
  • the wearer when the wearer uses the wearable ultrasonic nerve stimulation device, the wearer does not need to lie down, and only needs to put on the wearable parts like clothes.
  • the operation is simple and convenient, and the patient has a large of free space.
  • the relative position between the wearable component and the ultrasonic transducer can be adjusted through the connection structure, so that the ultrasonic transducer can have more action positions, and the operation error can be reduced.
  • the "wearer” or “user” of the wearable ultrasonic nerve stimulation device or system may be various identities, such as a doctor, a patient, and the like. References to the terms “doctor” and “patient” elsewhere in this document are for example only, and are not intended to be limiting, for example, in some situations a wearer may wear a wearable ultrasonic nerve stimulation device to conduct Stimulation operation, where the wearer is both the doctor and the patient.
  • FIG. 2 shows a schematic structural diagram of an example of a wearable ultrasonic nerve stimulation device according to an embodiment of the present application.
  • the wearable component 110 is a collapsible wearable component.
  • the wearable component can be adapted to the body or body shape of different wearers, thereby expanding the application range of the wearable nerve stimulation device.
  • the wearable part 110 may further include a retractable part 4 and a fixing screw 5 , and the retractable part 4 can be adjusted according to the size of different human bodies, so that the wearable part 110 can be adapted to different groups of people.
  • the size of the wearable component 110 can be fixed by the fixing screw 5 .
  • some soft materials such as sponge can be added to the inner surface of the wearable part 110 (which can be made of metal or carbon material, etc.) to reduce additional damage to the wearable part, for example, when the wearable part 110 is
  • the vest can play a role in protecting the shoulders and chest.
  • connection structure 120 is a retractable connection structure.
  • the connecting structure 120 includes a spring 7 and a support rod 8 , and the support rod 8 can be telescopically adjusted to different positions along the direction of the support rod 8 through the spring 7 .
  • the connecting structure 120 includes a connecting rod, and a first connecting member and a second connecting member disposed on the connecting rod.
  • the position of the wearable component relative to the connecting rod can be adjusted through the first connecting member, and the position of the ultrasonic transducer 130 relative to the connecting rod can be adjusted through the second connecting member. Therefore, the relative position between the wearable component and the ultrasonic transducer can be adjusted by adjusting the connecting piece provided on the connecting rod, so that the ultrasonic transducer has a larger operating position range.
  • the first connector includes a ball axle module for securing the connecting rod to the wearable component.
  • the ball shaft module has a free rotation function, so that the connecting rod can be driven by the ball shaft module to rotate, and the ball shaft module can adopt a variety of structures, for example, the ball shaft structure in the current car mobile phone bracket can be used. Unlimited. Therefore, by means of the ball-shaft connection, the connecting rod in multiple directions can be realized, which is helpful for positioning the ultrasonic transducer on the connecting rod to the required precise position.
  • corresponding ball axle modules may be respectively provided at a preset number of positions of the wearable component. Therefore, the ball axis module at a suitable position can be selected to fix the connecting rod according to the actual needs of ultrasonic stimulation, thereby expanding the position range of the connecting rod and the ultrasonic transducer.
  • the connecting rod may include a spring 7 , a supporting rod 8 , a movable rod 9 and a fixing screw 13
  • the first connecting member may include a ball axle module 6
  • the ball axis module 6 can be disposed on the wearable component 110
  • the support rod 8 can be fixed to the ball axis module 6 through the spring 7
  • the support rod 8 can be telescopically adjusted to different directions along the support rod 8 through the spring 7 Location.
  • the movable rod 9 can move relative to the supporting rod 8, for example, the supporting rod 8 can be a hollow structure, so that the movable rod 9 can move up and down in the supporting rod 8, and the movable rod 9 can also rotate relative to the supporting rod 8 (for example, rotate 360 degrees) ), and the movable rod 9 can be fixed to the support rod 8 by operating the corresponding fixing screws 13 when the movable rod 9 is adjusted to the desired position.
  • the supporting rod 8 can be a hollow structure, so that the movable rod 9 can move up and down in the supporting rod 8, and the movable rod 9 can also rotate relative to the supporting rod 8 (for example, rotate 360 degrees) ), and the movable rod 9 can be fixed to the support rod 8 by operating the corresponding fixing screws 13 when the movable rod 9 is adjusted to the desired position.
  • the ball axis module 6 may be similar to the structure of a vehicle mobile phone bracket, and has a free rotation function, so that the support rod 8 can be adjusted to different directions along with the ball axis module 6 .
  • the ball axle module includes an inner movable ball (not shown), an outer fixed ball (not shown) and a screw (not shown), and the inner movable ball can be rotated relative to the outer fixed ball and adjusted to a suitable When turning the screw, the outer fixed ball is tightened to fix the position of the inner movable ball.
  • the outer surface of the inner movable ball and the inner surface of the outer fixed ball may also be frosted or provided with concave and convex points, so as to increase the friction between the two balls and facilitate fixing the ball axle module at any position.
  • different positions of the wearable component 110 may be provided with a plurality of corresponding ball axis modules 6 , and the position of the ultrasonic stimulation may be adjusted according to the position of the ultrasonic stimulation.
  • the support rod 8 is arranged on the ball axis module at the corresponding position according to the requirements, which can meet the personalized ultrasound treatment requirements.
  • the second connector includes an ultrasonic transducer fixing module, which is used to rotate and adjust the position of the ultrasonic transducer.
  • the ultrasonic transducer fixing module can also adopt a ball shaft structure. In this way, an ultrasonic transducer with a larger position range can be realized, which is favorable for positioning the ultrasonic transducer to a required precise position.
  • the ultrasonic transducer fixing module and the connecting rod are connected by a rotating shaft, so that the ultrasonic transducer fixing module can move around the rotating shaft. Therefore, the steering of the ultrasonic transducer can be adjusted to multiple directions through the rotating shaft member, and the ultrasonic transducer in more directions can be realized, which is more favorable for positioning the ultrasonic transducer to the required position.
  • the second connector may include an ultrasonic transducer fixing module 15, and the ultrasonic transducer 130 is fixed by the ultrasonic transducer fixing module 15, and the ultrasonic transducer fixing module 15 has a rotation function,
  • the ultrasonic transducer fixing module 15 can fix the ultrasonic transducer 130 through a ball shaft module, so that the ultrasonic transducer 130 can rotate at multiple angles.
  • the ultrasonic transducer 130 may employ piezoelectric material or flexible transducer material, or the like.
  • the second connecting member may further include a spring 10 , a support rod 11 , a movable rod 12 , a fixing screw 13 and a handle-shaped screw 14 .
  • the support rod 11 is connected with the movable rod 9 through the handle-shaped screw 14, so that the support rod 11 can move around the handle-shaped screw 14 to adjust the support rod 11 and the ultrasonic transducer fixing module 15 to various directions.
  • the shaped screw 14 can also be replaced with other various types of rotating shaft members, so that the ultrasonic transducer fixing module 15 can move around the rotating shaft member, which is not limited herein.
  • the spring 10 may be arranged inside the support rod 11 so that the support rod 11 has the function of retracting and retracting back and forth.
  • the movable rod 12 can move relative to the support rod 11, for example, the support rod 11 can be a hollow structure, so that the movable rod 12 can move up and down in the support rod 11, and the movable rod 12 can also rotate relative to the support rod 11 (for example, rotate 360 degrees) ), and when the movable rod 12 is adjusted to a desired position, the movable rod 12 can be fixed to the support rod 11 by operating the corresponding fixing screws 13 , and one end of the movable rod 12 can also be connected with the ultrasonic transducer fixing module 15 . Therefore, by adjusting the positions of the support rod 8 and the movable rod 9, the position of the ultrasonic transducer fixing module 15 can be adjusted accordingly.
  • the movable rods (eg, 9 and 12 ) and the support rods (eg, 8 and 11 ) are cylindrical rod bodies, and the movable rods can freely rotate 360° relative to the support rods.
  • the support rod can be hollow, so the movable rod can slide up and down, far and near in the support rod to adjust the position according to actual needs.
  • the surface of the support rod may be frosted or provided with concave and convex points, which is beneficial for the fixing screw to firmly fix the support rod and the movable rod.
  • the movable rod and support rod can be selected from materials such as metal or carbon fiber.
  • the wearable ultrasonic nerve stimulation device is further provided with an arm rest 16 .
  • the arm rests 16 may be disposed on one side or the left and right sides of the wearable component 110 , so that the wearer can place his arms on the arm rests 16 when performing ultrasonic therapy on the wearer.
  • the wearable neurostimulation device may include a preset number of electrode devices (or electrode pads), which are provided on the wearable component (eg, vest) or connecting structure, and pass through the electrodes
  • the device may collect physiological feedback signals from the wearer of the wearable component (eg, the patient).
  • the signal transmission line connecting the electrode device is flexible, so that it can be adjusted freely according to the setting position of the electrode device. Therefore, the electrode device is directly arranged on the wearable component or the connection structure, which facilitates finding the electrode device in time and facilitates the collection process of the stimulation effect data of the wearable nerve stimulation device.
  • the type of physiological feedback signal should not be limited here, and may be determined according to the required stimulation effect data.
  • the wearable nerve stimulation device may include a preset number or a plurality of electrode devices 20 .
  • the electrode device 20 is disposed on the wearable component 110, so that the electrode device 20 can be integrated with the wearer to facilitate finding. It should be understood that the electrode device 20 can also be arranged at other positions of the wearable ultrasonic nerve stimulation device, for example, arranged on the connecting rod.
  • the signal transmission line connected to the electrode device 20 can be flexible, which facilitates the adjustment of the position of the electrode device.
  • the wearer's physiological feedback signals for example, brain electrical signals
  • changes in the wearer's physiological signals before and after ultrasound modulation are collected through the electrode device, so as to understand the effect of ultrasound therapy.
  • a retractable connecting rod that can rotate relative to the ball shaft of the wearable component
  • a ball shaft module that can fix the connecting rod in multiple positions
  • an ultrasonic transducer that can rotate and adjust the position of the ultrasonic transducer
  • the device fixing module helps to meet the needs of individualized precise nerve stimulation of different wearers.
  • the wearable component and the ultrasonic transducer are integrated into a whole, so that the wearer's freedom of movement is not restricted during the entire operation process of performing ultrasonic therapy on the wearer.
  • the shaft module, support rod, movable rod and ultrasonic transducer fixing module can be adjusted in multi-angle, multi-dimensional, high and low, far and near according to the specific position of the ultrasonic stimulation, which helps to adjust the ultrasonic transducer to a variety of desired location.
  • peripheral nerves including facial nerves, cervical vagus nerves, etc.
  • Central Nervous System a system for delivering ultrasound to peripheral nerves.
  • peripheral nerves including facial nerves, cervical vagus nerves, etc.
  • Central Nervous System a system for delivering ultrasound to peripheral nerves.
  • peripheral nerves including facial nerves, cervical vagus nerves, etc.
  • Central Nervous System a system for delivering ultrasound to peripheral nerves.
  • peripheral nerves including facial nerves, cervical vagus nerves, etc.
  • Central Nervous System Central Nervous System
  • FIG. 3 shows a structural block diagram of an example of a wearable ultrasonic nerve stimulation system according to an embodiment of the present application.
  • the wearable ultrasonic nerve stimulation system 300 includes the wearable ultrasonic nerve stimulation device 100 and a display 320 .
  • the wearable ultrasonic nerve stimulation device 100 includes a wearable component 110, an ultrasonic transducer 130 and a connecting structure 120, so that the wearer can receive the ultrasonic non-invasive treatment process like wearing clothes, which can improve the medical experience of ultrasonic stimulation.
  • the ultrasound transducer 130 may collect nerve image information, the display 320 may display the nerve image information, and the ultrasound transducer 130 may also output an ultrasound nerve stimulation signal.
  • the ultrasonic transducer may adopt various types, and may perform different operation processes according to different operating parameters (for example, driving signals used to define the power, frequency, and waveform of the ultrasonic signal, etc.).
  • driving signals used to define the power, frequency, and waveform of the ultrasonic signal, etc.
  • the image detection function or the ultrasound diagnosis function
  • the regulation and stimulation function is performed under the action of some driving signals (eg, the second driving signal).
  • the doctor can view the neural image information on the display through the ultrasonic transducer in the first working mode (for example, under the action of the first driving signal).
  • the specific position of the target point can be clearly seen on the display, which facilitates precise stimulation of the ultrasonic transducer under the second working mode (for example, under the action of the second driving signal).
  • the wearable ultrasonic nerve stimulation system 300 may further include an ultrasonic generator 330 electrically connected to the ultrasonic transducer 130 .
  • the ultrasonic generator 330 can generate driving signals (eg, corresponding to various types of operating parameters), and the ultrasonic transducer 130 can perform corresponding functional operations according to the driving signals input by the ultrasonic generator 330 , such as ultrasonic Detection function or ultrasound stimulation function.
  • the ultrasonic transducer 130 can collect nerve image information according to the first driving signal generated by the ultrasonic generator (for example, to explore the specific positions of the central nervous system and peripheral nerves such as the subcutaneous nerve and the vagus nerve, and the information generated by the ultrasonic generator
  • the second driving signal of the device outputs the ultrasonic nerve stimulation signal, so as to realize the function of precise positioning of the target point.
  • the ultrasonic generator 330 may receive a user operation to update the drive signal in a preset drive signal set, where the preset drive signal set includes a first drive signal and a second drive signal. Thereby, the switching of ultrasonic detection and ultrasonic stimulation functions can be realized by a user operation for the ultrasonic generator.
  • the function of the ultrasonic generator 330 ie, the function of generating a driving signal for the ultrasonic transducer
  • the user can directly operate the ultrasonic transducer by To realize the switch between the ultrasonic detection function and the ultrasonic stimulation function.
  • a preset number of electrode devices are provided on the wearable component or the connecting rod, and the display 320 may display the feedback result corresponding to the physiological feedback signal.
  • a plurality of electrode devices are connected to a receiver (such as a mobile terminal such as a computer and special equipment) through an elastic signal transmission cable. After the receiver performs signal filtering and conversion operations to obtain feedback results, the receiver The corresponding feedback results are displayed on the display of the .
  • the operator can view the effect of nerve stimulation in real time (for example, the effect of ultrasonic regulation of peripheral nerves) through the display, which facilitates timely correction of the stimulation plan and ensures high quality nerve stimulation process.
  • nerve stimulation for example, peripheral nerves
  • the operator can view the effect of nerve stimulation in real time (for example, the effect of ultrasonic regulation of peripheral nerves) through the display, which facilitates timely correction of the stimulation plan and ensures high quality nerve stimulation process.
  • various types of feedback signals can also be captured in various ways, so that the operator can view and evaluate the effect of nerve stimulation in real time, such as EMG, eye movement and brain CT (Computed Tomography, electronic computed tomography), MR (Magnetic Resonance, magnetic resonance) imaging and other signals.
  • a wearable ultrasonic stimulation nerve and brain wave feedback system which has the advantages of non-invasiveness, convenience and accuracy, and can meet the needs of personalized ultrasonic non-invasive treatment and operation. It will be appreciated that due to the non-invasive nature of ultrasound stimulation, ultrasound can be applied to peripheral nerve stimulation targeting different nerve nuclei in the central nervous system and different organs (eg, heart, spleen, liver, pancreas, gallbladder), and by Stimulating different organ targets can intervene in related diseases.
  • organs eg, heart, spleen, liver, pancreas, gallbladder
  • the nerve stimulation device in the embodiment of the present application is wearable, and the use process is simple and convenient, so that the person being stimulated can move freely, and the target point (ie, the nerve position) can be stimulated more quickly, accurately and individually, so that the While increasing compliance, it can also improve the efficiency and success of ultrasound stimulation of peripheral nerves.
  • the facial nerve and the cervical vagus nerve can be stimulated non-invasively, quickly and accurately through the ultrasonic transducer, and the electroencephalogram, electromyography, eye movement can be used simultaneously.
  • imaging means to provide real-time feedback on the effect of stimulation, which perfectly realizes the closed-loop stimulation and regulation of the ultrasonic nervous system.
  • the disclosed apparatus/terminal device and method may be implemented in other manners.
  • the apparatus/terminal device embodiments described above are only illustrative.
  • the division of the modules or units is only a logical function division. In actual implementation, there may be other division methods, such as multiple units. Or components may be combined or may be integrated into another system, or some features may be omitted, or not implemented.
  • the shown or discussed mutual coupling or direct coupling or communication connection may be through some interfaces, indirect coupling or communication connection of devices or units, and may be in electrical, mechanical or other forms.
  • the units described as separate components may or may not be physically separated, and components displayed as units may or may not be physical units, that is, may be located in one place, or may be distributed to multiple network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution in this embodiment.
  • each functional unit in each embodiment of the present application may be integrated into one processing unit, or each unit may exist physically alone, or two or more units may be integrated into one unit.
  • the above-mentioned integrated units may be implemented in the form of hardware, or may be implemented in the form of software functional units.
  • the integrated modules/units if implemented in the form of software functional units and sold or used as independent products, may be stored in a computer-readable storage medium.
  • the present application can implement all or part of the processes in the methods of the above embodiments, and can also be completed by instructing the relevant hardware through a computer program.
  • the computer program can be stored in a computer-readable storage medium, and the computer When the program is executed by the processor, the steps of the foregoing method embodiments can be implemented.
  • the computer program includes computer program code, and the computer program code may be in the form of source code, object code, executable file or some intermediate form, and the like.
  • the computer-readable medium may include: any entity or device capable of carrying the computer program code, recording medium, U disk, removable hard disk, magnetic disk, optical disk, computer memory, read-only memory (ROM, Read-Only Memory) , Random Access Memory (RAM, Random Access Memory), electric carrier signal, telecommunication signal and software distribution medium, etc. It should be noted that the content contained in the computer-readable media may be appropriately increased or decreased according to the requirements of legislation and patent practice in the jurisdiction, for example, in some jurisdictions, according to legislation and patent practice, the computer-readable media Electric carrier signals and telecommunication signals are not included.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Percussion Or Vibration Massage (AREA)

Abstract

La présente invention concerne un appareil et un système de neurostimulation ultrasonore à porter sur soi, dans le domaine technique des dispositifs médicaux. L'appareil comprend : un composant à porter sur soi ; un transducteur ultrasonore, utilisé pour émettre un signal ultrasonore de neurostimulation ; une structure de liaison, reliant le composant à porter sur soi et le transducteur ultrasonore, et utilisée pour ajuster la position relative entre le composant à porter sur soi et le transducteur ultrasonore. Ainsi, un utilisateur peut porter le composant à porter sur soi de la même manière qu'un vêtement et bénéficier du traitement par neurostimulation, et l'utilisateur peut se déplacer librement afin de bénéficier d'une meilleure expérience du traitement ultrasonore. En outre, le transducteur ultrasonore dispose d'une plus grande plage de positions de fonctionnement, ce qui permet de réduire les erreurs de fonctionnement.
PCT/CN2020/101386 2020-07-10 2020-07-10 Appareil et système de neurostimulation ultrasonore pouvant être porté sur soi Ceased WO2022006865A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/CN2020/101386 WO2022006865A1 (fr) 2020-07-10 2020-07-10 Appareil et système de neurostimulation ultrasonore pouvant être porté sur soi

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2020/101386 WO2022006865A1 (fr) 2020-07-10 2020-07-10 Appareil et système de neurostimulation ultrasonore pouvant être porté sur soi

Publications (1)

Publication Number Publication Date
WO2022006865A1 true WO2022006865A1 (fr) 2022-01-13

Family

ID=79552208

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2020/101386 Ceased WO2022006865A1 (fr) 2020-07-10 2020-07-10 Appareil et système de neurostimulation ultrasonore pouvant être porté sur soi

Country Status (1)

Country Link
WO (1) WO2022006865A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105944245A (zh) * 2016-05-31 2016-09-21 深圳先进技术研究院 头戴式超声换能器
US20170311923A1 (en) * 2016-03-21 2017-11-02 Isono Health, Inc. Wearable ultrasound system and method
CN207796503U (zh) * 2018-01-16 2018-08-31 瓦斯菲·阿希达法特 智能设备载体
CN108542427A (zh) * 2018-04-08 2018-09-18 深圳市贝斯曼精密仪器有限公司 一种可穿戴式超声多普勒血流检测仪及检测方法
CN111195397A (zh) * 2018-11-19 2020-05-26 乾智(上海)医疗科技有限公司 一种便携式超声治疗系统

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170311923A1 (en) * 2016-03-21 2017-11-02 Isono Health, Inc. Wearable ultrasound system and method
CN105944245A (zh) * 2016-05-31 2016-09-21 深圳先进技术研究院 头戴式超声换能器
CN207796503U (zh) * 2018-01-16 2018-08-31 瓦斯菲·阿希达法特 智能设备载体
CN108542427A (zh) * 2018-04-08 2018-09-18 深圳市贝斯曼精密仪器有限公司 一种可穿戴式超声多普勒血流检测仪及检测方法
CN111195397A (zh) * 2018-11-19 2020-05-26 乾智(上海)医疗科技有限公司 一种便携式超声治疗系统

Similar Documents

Publication Publication Date Title
WO2024013267A1 (fr) Dispositifs et procédés de thérapie par ultrasons pouvant être portés et automatisés
Yu et al. Design of a volumetric imaging sequence using a vantage-256 ultrasound research platform multiplexed with a 1024-element fully sampled matrix array
CN110520054B (zh) 医疗用头部装置以及包括医疗用头部装置的经颅超声波传输装置
CN102793980B (zh) 双频聚焦超声系统
CN109310390A (zh) 电疗治疗
CN111921101A (zh) 头戴式超声神经刺激装置及系统
US12053652B2 (en) Wearable and automated ultrasound therapy devices and methods
US10493272B1 (en) Inferential electrical stimulation device with targeting capabilities
CN107073290A (zh) 超声波套筒及利用其的超声波治疗头
CN110013434B (zh) 一种具备针法指导功能的智能超声针灸仪
CN111544882A (zh) 一种基于脑机接口的新型脑卒中下肢主动康复系统及应用
CN110477917A (zh) 脑内淋巴管刺激系统、方法及控制装置
CN118829398A (zh) 用于个人可穿戴电子设备的系统和方法
WO2024239607A1 (fr) Système et procédé de régulation et de commande de ganglions lymphatiques
WO2022006866A1 (fr) Appareil et système de stimulation nerveuse à ultrasons monté sur la tête
CN114712735B (zh) 一种神经退行性疾病超声治疗仪及其使用方法
WO2022006865A1 (fr) Appareil et système de neurostimulation ultrasonore pouvant être porté sur soi
CN111921102A (zh) 穿戴式超声神经刺激装置及系统
US20240181277A1 (en) Wearable and automated ultrasound therapy devices and methods
CN2850642Y (zh) 一种组合型超声波治疗装置的治疗头
CN111863227A (zh) 超声聚焦控制方法、装置、电子设备及存储介质
CN114904172A (zh) 基于低强度聚焦超声的便携式神经调控装置和调控方法
CN100484588C (zh) 一体式多功能电子耳膜
CN217988181U (zh) 一种挂耳式声光智能化无损骨传导治疗仪
CN220256985U (zh) 一种移动式理疗仪

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 20944609

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 20944609

Country of ref document: EP

Kind code of ref document: A1

122 Ep: pct application non-entry in european phase

Ref document number: 20944609

Country of ref document: EP

Kind code of ref document: A1

32PN Ep: public notification in the ep bulletin as address of the adressee cannot be established

Free format text: NOTING OF LOSS OF RIGHTS PURSUANT TO RULE 112(1) EPC (EPO FORM 1205 DATED 03.07.2023)

122 Ep: pct application non-entry in european phase

Ref document number: 20944609

Country of ref document: EP

Kind code of ref document: A1