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WO2014088135A1 - Composition de shampooing à effets anti-inflammatoire et antiallergique et fonction de croissance des cheveux - Google Patents

Composition de shampooing à effets anti-inflammatoire et antiallergique et fonction de croissance des cheveux Download PDF

Info

Publication number
WO2014088135A1
WO2014088135A1 PCT/KR2012/010583 KR2012010583W WO2014088135A1 WO 2014088135 A1 WO2014088135 A1 WO 2014088135A1 KR 2012010583 W KR2012010583 W KR 2012010583W WO 2014088135 A1 WO2014088135 A1 WO 2014088135A1
Authority
WO
WIPO (PCT)
Prior art keywords
brier
composition
extract
inflammatory
preparation example
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2012/010583
Other languages
English (en)
Korean (ko)
Inventor
김학수
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SAMBU MEDICAL CO Ltd
Original Assignee
SAMBU MEDICAL CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SAMBU MEDICAL CO Ltd filed Critical SAMBU MEDICAL CO Ltd
Priority to PCT/KR2012/010583 priority Critical patent/WO2014088135A1/fr
Publication of WO2014088135A1 publication Critical patent/WO2014088135A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/75—Anti-irritant

Definitions

  • the present invention relates to a shampoo composition having anti-inflammatory and anti-allergic effect and hair growth function.
  • Hair loss has been estimated to be caused mainly by abnormal endocrine system such as hormonal imbalance, autonomic nervous system, circulatory system such as blood circulation disorder, excessive nutrition of hair roots, malnutrition of hair root, allergy, bacterial infection and genetic factors, and aging.
  • abnormal endocrine system such as hormonal imbalance, autonomic nervous system, circulatory system such as blood circulation disorder, excessive nutrition of hair roots, malnutrition of hair root, allergy, bacterial infection and genetic factors, and aging.
  • the cause of environmental factors such as mental stress, air pollution, and food from complex environments has been raised.
  • hair and scalp are part of the body, and as they age, they appear aging. As aging progresses, various changes and problems appear in the hair and scalp.
  • the technical problem to be achieved in the present invention is to ultimately relieve scalp irritation and inflammation, protect hair and strengthen hair roots to prevent hair loss, to provide a method for producing a scalp heat lowering and moisturizing shampoo composition It is to.
  • Another technical problem to be achieved in the present invention is to provide a scalp heat lowering and moisturizing shampoo composition prepared according to the manufacturing method.
  • Shampoo composition having anti-inflammatory and anti-allergic effect and hair growth function, characterized in that the cord, geunpi, brier complex extract contained 30 to 36% by weight per total weight of the composition.
  • the shampoo composition according to the present invention also has an anti-inflammatory and anti-allergic effect and the effect of maintaining hair growth function and moisturizing, and ultimately can reduce hair loss by alleviating scalp irritation and inflammation, protecting hair and strengthening the hair root, It is expected to be very useful in the field.
  • Shampoo composition having anti-inflammatory and anti-allergic effect and hair growth function, characterized in that the cord, geunpi, brier complex extract contained 30 to 36% by weight per total weight of the composition.
  • the present invention provides a cosmetic composition for alleviating skin irritation, which comprises an abrasive line, a medicinal bark, a brier complex extract as an active ingredient.
  • a cosmetic composition for alleviating skin irritation which comprises an abrasive line, a medicinal bark, a brier complex extract as an active ingredient.
  • the abrasive line, the bark and brier complex extract is preferably contained in 30 to 36% by weight per weight of the composition, more preferably 32 to 34 per weight of the composition. It is preferably contained in weight percent.
  • a shampoo containing 10% by weight of the abrasive cord, the bark and brier complex extract prepared in Example 1 was prepared.
  • the skin stimulating alleviation effect in the cosmetic composition for skin stimulation alleviation of the present invention is characterized in that the cell protective effect against the stimulating source, the anti-inflammatory effect through the inhibition of iNOS, and the anti-allergic effect by the inhibition of histamine secretion can be confirmed.
  • the skin cell protective effect on the stimulant, the activity of inflammatory mediators and the release of histamine of the allergic reaction were measured.
  • the cytoprotective effect on the stimulating agent, the inhibitory effect of inflammatory factors and the histamine release inhibitory effect were excellent. This suggests that the extract of Mahjong, Japonica and Briernab of the present invention can significantly reduce inflammation and allergic reactions and confirm the skin irritation effect by protecting the cells.
  • the extract of the abrasive wire, the bark and brier complex extract is extracted with a polar solvent or a nonpolar solvent.
  • the polar solvent may be any polar solvent that can be used for extracting abrasion cord, bark, brier, but preferably water, methanol, ethanol, butanol or a mixed solvent thereof.
  • the non-polar solvent may be any non-polar solvent that can be used for extracting abrasion line, bark, brier, but preferably hexane, glycerin, butylene glycol, chloroform or ethyl acetate.
  • Purified water extract was prepared by following the same reaction process as in Preparation Example 1 except for changing 80% ethanol to purified water.
  • a 30% ethanol extract was prepared by performing the same reaction process as in Preparation Example 1 except that 80% ethanol was changed to 30% ethanol.
  • a butanol extract was prepared by following the same reaction procedure as in Preparation Example 1 except for changing 80% ethanol to butanol.
  • a 30% glycerin extract was prepared by performing the same reaction process as in Preparation Example 1 except that 80% ethanol was changed to 30% glycerin.
  • All cells of the following experimental example was purchased from ATCC (America Type Culture Collect, USA) and used through subculture. All cells were cultured in a cell incubator (ELITE II, Revco, USA) at 37 ° C., 5% CO 2 conditions.
  • MTT thiazolyl blue tetrazolium bromide
  • the complex extract was confirmed that there is no toxicity in skin cells.
  • RAW 264.7 cultured in Experimental Example 1 was inoculated into a 24 well plate at a density of 8 ⁇ 10 5 cells / well, and cultured for 1 day, and then 0.1 ⁇ g of LPS (lipopolysaccharide from E.coli , Sigma, USA), an inflammatory response substance / ml containing phenol-red free DMEM was replaced and the extract was added to each concentration was incubated for 1 day.
  • LPS lipopolysaccharide from E.coli , Sigma, USA
  • the complex extract was shown to have an anti-inflammatory effect by inhibiting iNOS activity, an inflammatory factor.
  • the extract of Preparation Example 1 was found to inhibit the iNOS activity very well. Therefore, according to the results of the iNOS activity inhibition experiment, the extract of Preparation Example 1 was determined to be very good for stimulation relaxation, and the following experiment was used to verify the efficacy using the Extract Preparation Example 1.
  • the complex extract was confirmed that the cell protection effect on the stimulation source is excellent.
  • ⁇ -Hexosaminidase is released together with histamine, and ⁇ -Hexosaminidase released can be used as an indicator of degranulation ( Planta Med . 64, 577-578 (1998)).

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

L'invention concerne une composition de shampooing à effets anti-inflammatoire et antiallergique, et une fonction de croissance des cheveux. La composition contient un extrait combiné de Trachelospermum asiaticum, de Melia azedarach Linne var. japonica Makino et de Rosa multiflora thumb. var. multiflora, la teneur de l'extrait combiné de Trachelospermum asiaticum, de Melia azedarach Linne var. japonica Makino et de Rosa multiflora thumb. var. multiflora représentant 30 à 36 % en poids du poids total de la composition.
PCT/KR2012/010583 2012-12-06 2012-12-06 Composition de shampooing à effets anti-inflammatoire et antiallergique et fonction de croissance des cheveux Ceased WO2014088135A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/KR2012/010583 WO2014088135A1 (fr) 2012-12-06 2012-12-06 Composition de shampooing à effets anti-inflammatoire et antiallergique et fonction de croissance des cheveux

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2012/010583 WO2014088135A1 (fr) 2012-12-06 2012-12-06 Composition de shampooing à effets anti-inflammatoire et antiallergique et fonction de croissance des cheveux

Publications (1)

Publication Number Publication Date
WO2014088135A1 true WO2014088135A1 (fr) 2014-06-12

Family

ID=50883542

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/010583 Ceased WO2014088135A1 (fr) 2012-12-06 2012-12-06 Composition de shampooing à effets anti-inflammatoire et antiallergique et fonction de croissance des cheveux

Country Status (1)

Country Link
WO (1) WO2014088135A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000022127A (ko) * 1997-05-19 2000-04-25 겜마 아키라 두부용 조성물
KR20090010178A (ko) * 2006-03-31 2009-01-29 파나세아 바이오테크 리미티드 모발장애에 대한 새로운 조성물 및 이의 조제방법
KR101002012B1 (ko) * 2010-04-01 2010-12-16 주식회사 뉴앤뉴 산딸나무, 찔레나무, 비자나무, 파초 및 죽절초 혼합물의 추출물을 함유하는 화장료 조성물
KR20110083817A (ko) * 2010-01-15 2011-07-21 주식회사 알엔에스 피부 염증 개선용 화장료 조성물
KR20120046564A (ko) * 2010-11-02 2012-05-10 (주)로다멘코스메딕스 천련자 추출물을 유효성분으로 함유하는 발모 및 두피 관리용 조성물
KR20120061725A (ko) * 2010-12-03 2012-06-13 신일제약주식회사 낙석등 및 목단피의 추출 혼합물을 유효성분으로 포함하는 염증성 질환 예방 또는 치료용 약제학적 조성물 및 상기 조성물의 제조방법

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000022127A (ko) * 1997-05-19 2000-04-25 겜마 아키라 두부용 조성물
KR20090010178A (ko) * 2006-03-31 2009-01-29 파나세아 바이오테크 리미티드 모발장애에 대한 새로운 조성물 및 이의 조제방법
KR20110083817A (ko) * 2010-01-15 2011-07-21 주식회사 알엔에스 피부 염증 개선용 화장료 조성물
KR101002012B1 (ko) * 2010-04-01 2010-12-16 주식회사 뉴앤뉴 산딸나무, 찔레나무, 비자나무, 파초 및 죽절초 혼합물의 추출물을 함유하는 화장료 조성물
KR20120046564A (ko) * 2010-11-02 2012-05-10 (주)로다멘코스메딕스 천련자 추출물을 유효성분으로 함유하는 발모 및 두피 관리용 조성물
KR20120061725A (ko) * 2010-12-03 2012-06-13 신일제약주식회사 낙석등 및 목단피의 추출 혼합물을 유효성분으로 포함하는 염증성 질환 예방 또는 치료용 약제학적 조성물 및 상기 조성물의 제조방법

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