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WO2010058984A2 - Composition anti-oxydante contenant un extrait traité de chrisanthème ou de pelure de mandarine satsuma - Google Patents

Composition anti-oxydante contenant un extrait traité de chrisanthème ou de pelure de mandarine satsuma Download PDF

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Publication number
WO2010058984A2
WO2010058984A2 PCT/KR2009/006837 KR2009006837W WO2010058984A2 WO 2010058984 A2 WO2010058984 A2 WO 2010058984A2 KR 2009006837 W KR2009006837 W KR 2009006837W WO 2010058984 A2 WO2010058984 A2 WO 2010058984A2
Authority
WO
WIPO (PCT)
Prior art keywords
extract
chrysanthemum indicum
citrus unshiu
unshiu peel
unprocessed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2009/006837
Other languages
English (en)
Other versions
WO2010058984A3 (fr
Inventor
Dong Hyun Kim
Jun Seong Park
Jae Kyoung Lee
Hye Yoon Park
Soo Mi Ahn
Duck Hee Kim
Han Kon Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amorepacific Corp
Original Assignee
Amorepacific Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amorepacific Corp filed Critical Amorepacific Corp
Priority to CN2009801447024A priority Critical patent/CN102209525B/zh
Priority to US13/128,700 priority patent/US9700506B2/en
Priority to JP2011536264A priority patent/JP5597642B2/ja
Publication of WO2010058984A2 publication Critical patent/WO2010058984A2/fr
Publication of WO2010058984A3 publication Critical patent/WO2010058984A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0212—Face masks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers

Definitions

  • the present invention relates to an antioxidant cosmetic composition, and more particularly to an antioxidant cosmetic composition containing, as an active ingredient, either an extract of at least one of Chrysanthemum indicum and Citrus unshiu peel, processed using a medicinal herb processing technique, or a mixture of said extract and an extract of at least one of unprocessed Chrysanthemum indicum and Citrus unshiu peel.
  • a medicinal herb processing technique that is a traditional Chinese medicine manufacturing technique is called “Po-je”, “Hap-hwa”, “Hap-yak”, “Su-chi”, “Po-ja”, “Bub- je” and “Su-sa” in Korean.
  • This technique can be defined as a medicine manufacturing technique of changing the inherent properties of medicinal herbs by processing the medicinal herbs on the basis of the Chinese medicine theory.
  • the objects of processing medicinal herbs are to clarify medicines, facilitate the storage of medicines, reduce or remove the toxicity or side effects of medicines, change the properties of medicines to make the medicines more effective, enhance the therapeutic effects of medicines, and the offensive odor and taste of medicines to facilitate the intake of the medicines.
  • the present inventors have conducted studies on natural materials having excellent antioxidant effects and, as a result, have found that, when a cosmetic composition is prepared using an extract of processed Chrysanthemum indicum or Citrus unshiu peel alone or in a mixture with an extract of unprocessed Chrysanthemum indicum or Citrus unshiu peel, the prepared composition shows a very excellent antioxidant effect, thereby completing the present invention.
  • the present invention provides an antioxidant cosmetic composition containing, as an active ingredient, an extract of at least one of processed Chrysanthemum indicum and Citrus unshiu peel.
  • the present invention provides an antioxidant cosmetic composition containing a mixture of an extract of at least one of processed Chrysanthemum indicum and Citrus unshiu peel and an extract of at least one of unprocessed Chrysanthemum indicum and Citrus unshiu peel.
  • the cosmetic composition according to the present invention contains an extract of at least one of processed Chrysanthemum indicum and Citrus unshiu peel alone or in a mixture with an extract of at least one of unprocessed Chrysanthemum indicum and Citrus unshiu peel, and thus has an excellent antioxidant effect of inhibiting DPPH oxidation.
  • the present invention relates to an antioxidant cosmetic composition containing, as an active ingredient, an extract of at least one of processed Chrysanthemum indicum and Citrus unshiu peel.
  • the present invention also relates to an antioxidant cosmetic composition containing a mixture of an extract of at least one of processed Chrysanthemum indicum and Citrus unshiu peel and an extract of at least one of unprocessed Chrysanthemum indicum and Citrus unshiu peel.
  • the extract of the unprocessed plant which is mixed with the extract of the processed plant, is prepared from a plant different from a plant used to prepare the extract of the processed plant.
  • a cosmetic composition according to a preferred embodiment of the present invention may contain, as active ingredients, an extract of unprocessed Chrysanthemum indicum and an extract of processed Citrus unshiu peel.
  • extract of the unprocessed plant refers to an extract obtained by extracting Chrysanthemum indicum or Citrus unshiu peel with water or an organic solvent, which are conventionally used, without processing the plant.
  • Chrysanthemum indicum which is used in the present invention is called "Hwang- kook” or "Gam-kook” in Korean.
  • This plant grows mainly in the mountains and has short hairs throughout thereof. The stem reaches a height of 60-90 cm and is black, slender and long. Umbel flower heads open on the upper portion of the stem in September to October.
  • Chinese medicine the plant is used to treat a fever, pneumonia, bronchitis, headache, gastritis, enteritis, a swell and the like.
  • folk remedies the plant is attached to the affected area of the body in a pulverized state, or the affected area is washed with a liquid obtained by boiling the plant in water.
  • the flower of Chrysanthemum indicum is used in a dried form, but the scope of the present invention is not limited thereto.
  • Citrus unshiu peel which is used in the present invention refers to the peel of Citrus unshiuMarkovich and is generally obtained by harvesting and drying Citrus unshiu Markovich in October to November. It contains volatile essential oil, hesperidin (flavone glycoside), citric acid, vitamin B 1 and the like. Citrus unshiu peel is described in the literature as follows. Citrus unshiu peel is warm in nature, nontoxic, and hot and bitter in taste. It acts mainly in the spleen meridian and also acts in the lung meridian and the stomach meridian.
  • the cosmetic composition according to the present invention is characterized in that it contains extracts prepared by processing each of Chrysanthemum indicum and Citrus unshiu peel and extracting each of the processed plants with an organic solvent.
  • Extracts of Chrysanthemum indicum and Citrus unshiu peel can be prepared through a method comprising the steps of:
  • step a) adding honey to Chrysanthemum indicum or Citrus unshiu peel and allowing the added honey to be absorbed into the plant for 30 minutes to 1 hour; [25] b) roasting the plant of step a) at 100-180 0 C for 10 minutes to 1 hour; and
  • the honey in step a) is added in an amount of 20-30 wt% based on the weight of
  • the extraction in step c) can be carried out according to any conventional method known in the art.
  • an extract of each of the Chrysanthemum indicum and Citrus unshiu peel can be obtained by adding water or an organic solvent to each of Chrysanthemum indicum and Citrus unshiu peel, extracting the plant under reflux in the solvent, dipping the extract in the solvent, filtering the extract through filter cloth, centrifuging the filtered extract to separate it into the residue and the filtrate, and concentrating the separated filtrate under reduced pressure.
  • the organic solvent which is used in the present invention can be selected from the group consisting of ethanol, methanol, butanol, ether, ethyl acetate, chloroform, and mixtures of these solvents with water.
  • the extraction temperature is preferably 10-80 0 C, and the extraction time is preferably 6-24 hours. If the extraction temperature and time are out of the above- specified ranges, the extraction efficiency can be reduced or the changes in the components of the extract can occur.
  • the extract may be macerated at room temperature according to a conventional method known in the art, and the macerated extract may be heated and filtered, thus obtaining a liquid- phase material.
  • the extract may additionally be evaporated to remove the solvent or be spray-dried or freeze-dried.
  • the cosmetic composition according to the present invention contains one or a mixture of the extracts of processed Chrysanthemum indicum and Citrus unshiu peel in an amount of 0.0001-30 wt% based on the total weight of the composition. If the content of the extract in the cosmetic composition is less than 0.0001 wt%, the antioxidant effect of the extract cannot be obtained, and if the content exceeds 30 wt%, the increase in the content will not lead to a significant increase in the effect of the extract and it will be difficult to maintain stability or prepare a formulation.
  • the mixture of the extracts of processed Chrysanthemum indicum and Citrus unshiu peel is used, the mixture is preferably contained in an amount of 0.0001-30 wt% based on the total weight of the composition, and each of the components of the mixture may be used in an amount suitably selected from the range of 0.0001 to 30 wt% based on total weight of the composition.
  • the extracts of processed Chrysanthemum indicum and Citrus unshiu peel are used at a weight ratio of 1 : 1.
  • the cosmetic composition according to the present invention may contain, in addition to the extract of at least one of processed Chrysanthemum indicum and Citrus unshiu peel, an extract of at least one of unprocessed Chrysanthemum indicum and Citrus unshiu peel.
  • the extract of unprocessed Chrysanthemum indicum or Citrus unshiu peel is prepared by extracting Chrysanthemum indicum or Citrus unshiu peel with water or an organic solvent without processing the plant, and the preparation process thereof is the same as the above-described extraction process of step c).
  • the extract of the unprocessed plant, which is mixed with the extract of the processed plant is prepared from a plant different from a plant used to prepare the extract of the processed plant.
  • the cosmetic composition according to the present invention contains an extract of at least one of processed Chrysanthemum indicum and Citrus unshiu peel and an extract of unprocessed Chrysanthemum indicum and Citrus unshiu peel in an amount of 0.0001-30 wt% based on the total weight of the composition. If the content of the extracts in the composition is less than 0.0001 wt%, the antioxidant effect of the extract cannot be obtained, and if the content exceeds 30 wt%, the increase in the content will not lead to a significant increase in the effects of the extracts and it will be difficult to maintain stability or prepare a formulation.
  • the mixture of the extract of processed Chrysanthemum indicum or Citrus unshiu peel with the extract of unprocessed Chrysanthemum indicum or Citrus unshiu peel is used, the mixture is preferably contained in an amount of 0.0001-30 wt% based on the total weight of the composition, and each of the components of the mixture may be used in an amount suitably selected from the range of 0.0001 to 30 wt% based on the total weight of the composition.
  • the extracts of the mixture are used in equal amounts.
  • the cosmetic composition of the present invention can be formulated as a skin lotion, an astringent lotion, a milk lotion, a nourishing cream, a massage cream, an essence, a pack, a foundation, a lipstick or a powder foundation, but the scope of the present invention is not limited thereto.
  • components other than the extract in the cosmetic composition can be suitably selected by a skilled in the art depending on the formulation or intended use of the cosmetic composition.
  • Example 1 Preparation of extract of honev-roasted Citrus unshiu peel
  • Example 4 Preparation of mixture of extracts of honey-roasted Citrus unshiu peel and unprocessed Chrysanthemum indicum
  • Example 5 Preparation of mixture of extracts of honev-roasted Citrus unshiu peel and Chrysanthemum indicum
  • IC 50 means the sample concentration at which the absorbance is reduced by 50%.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne une composition cosmétique anti-oxydante, et en particulier une composition cosmétique anti-oxydante contenant, en tant que principe actif, soit un extrait de chrisanthème (Chrysanthemum indicum) et/ou de pelure de mandarine satsuma (Citrus unshiu) traité à l'aide d'une technique de traitement de plantes médicinales, soit un mélange dudit extrait et d'un extrait non traité de chrisanthème (Chrysanthemum indicum) et/ou de pelure de mandarine satsuma (Citrus unshiu).
PCT/KR2009/006837 2008-11-19 2009-11-19 Composition anti-oxydante contenant un extrait traité de chrisanthème ou de pelure de mandarine satsuma Ceased WO2010058984A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN2009801447024A CN102209525B (zh) 2008-11-19 2009-11-19 含有经加工的野菊花或温州蜜柑皮的提取物的抗氧化剂组合物
US13/128,700 US9700506B2 (en) 2008-11-19 2009-11-19 Antioxidant composition containing extract of processed Chrysanthemum indicum or Citrus unshiu peel
JP2011536264A JP5597642B2 (ja) 2008-11-19 2009-11-19 炮製処理された甘菊及び陳皮の抽出物を含有する抗酸化用化粧料組成物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2008-0115369 2008-11-19
KR1020080115369A KR101537293B1 (ko) 2008-11-19 2008-11-19 포제 처리된 감국 또는 진피 추출물을 함유하는 항산화용 화장료 조성물

Publications (2)

Publication Number Publication Date
WO2010058984A2 true WO2010058984A2 (fr) 2010-05-27
WO2010058984A3 WO2010058984A3 (fr) 2010-09-30

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Application Number Title Priority Date Filing Date
PCT/KR2009/006837 Ceased WO2010058984A2 (fr) 2008-11-19 2009-11-19 Composition anti-oxydante contenant un extrait traité de chrisanthème ou de pelure de mandarine satsuma

Country Status (5)

Country Link
US (1) US9700506B2 (fr)
JP (1) JP5597642B2 (fr)
KR (1) KR101537293B1 (fr)
CN (1) CN102209525B (fr)
WO (1) WO2010058984A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014533722A (ja) * 2011-11-23 2014-12-15 株式会社アモーレパシフィックＡｍｏｒｅｐａｃｉｆｉｃ Ｃｏｒｐｏｒａｔｉｏｎ 白色シマカンギク抽出物を含有する皮膚外用剤組成物

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101480696B1 (ko) * 2008-11-19 2015-01-09 (주)아모레퍼시픽 사삼, 고본 및 생약 추출물을 포함하는 것을 특징으로 하는화장료 조성물
CN116602901A (zh) * 2023-05-23 2023-08-18 广东省科学院江门产业技术研究院有限公司 一种含柑皮提取物的化妆品组合物及制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63170323A (ja) * 1986-12-29 1988-07-14 Cosmo Kaihatsu Kk 抗アレルギ−剤
CN1102787A (zh) * 1993-12-22 1995-05-24 屈天时 一种营养口服液的制备方法
JP3343708B2 (ja) * 1995-07-14 2002-11-11 森谷健康食品株式会社 安眠用健康食品
US6726940B2 (en) * 1997-09-18 2004-04-27 Societe L'oreal S.A. Use of at least one extract of the genus chrysanthemum for assisting skin and/or hair pigmentation
JPH11246336A (ja) * 1998-02-27 1999-09-14 Ichimaru Pharcos Co Ltd 活性酸素消去剤及び美肌化粧料組成物
WO2002000239A1 (fr) * 2000-06-28 2002-01-03 Kikkoman Corporation Agents anti-allergiques, medicaments, aliments, boissons ou produits cosmetiques contenant ces agents et procedes permettant de produire ceux-ci
US20040223942A1 (en) * 2003-03-06 2004-11-11 Kao Corporation Skin aging-preventing or improving agent
CN1586248B (zh) * 2004-10-15 2011-10-12 高思 保健饮品
KR101189989B1 (ko) * 2005-06-30 2012-10-12 (주)아모레퍼시픽 문형 추출물을 유효성분으로 함유하는 화장료 조성물
KR101483440B1 (ko) * 2008-05-02 2015-01-19 (주)아모레퍼시픽 포제를 활용한 약용식물 추출물 및 이를 함유하는 피부외용제 조성물

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BAE CHEON CHA ET AL.: 'Antioxidative effect of domestic plants' KOR. J. PHARMACOGN. vol. 28, no. 1, 1997, pages 15 - 20 *
JUNG SIK YOU ET AL.: 'Quality characteristics of Chrysathemum indicum L. Flower Tea in relation to the number of pan-firing' J. KOREAN SOC. FOOD. SCI. NUTR. vol. 37, no. 5, 31 May 2008, pages 647 - 652 *
KYUNG MI YOO ET AL.: 'Antioxidant activity and physicochemical Characteristics of Tangerine peel tea prepared with Cirtrus unshiu cultivated in Cheju' KOREAN J. FOOD COOKERY SCI. vol. 21, no. 3, June 2005, pages 354 - 359 *
SUNG JE JUNG ET AL.: 'Screening for antioxidant activity of plant medicinal extracts' J. KOREAN SOC. APPL. BIOL. CHEM. vol. 47, no. 1, 2004, pages 135 - 140 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014533722A (ja) * 2011-11-23 2014-12-15 株式会社アモーレパシフィックＡｍｏｒｅｐａｃｉｆｉｃ Ｃｏｒｐｏｒａｔｉｏｎ 白色シマカンギク抽出物を含有する皮膚外用剤組成物

Also Published As

Publication number Publication date
CN102209525A (zh) 2011-10-05
KR101537293B1 (ko) 2015-07-16
KR20100056282A (ko) 2010-05-27
JP5597642B2 (ja) 2014-10-01
JP2012512813A (ja) 2012-06-07
US20110223265A1 (en) 2011-09-15
CN102209525B (zh) 2013-04-24
US9700506B2 (en) 2017-07-11
WO2010058984A3 (fr) 2010-09-30

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