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WO2010070086A3 - Method for the enzymatic reaction of alkanes - Google Patents

Method for the enzymatic reaction of alkanes Download PDF

Info

Publication number
WO2010070086A3
WO2010070086A3 PCT/EP2009/067493 EP2009067493W WO2010070086A3 WO 2010070086 A3 WO2010070086 A3 WO 2010070086A3 EP 2009067493 W EP2009067493 W EP 2009067493W WO 2010070086 A3 WO2010070086 A3 WO 2010070086A3
Authority
WO
WIPO (PCT)
Prior art keywords
alkanes
enzymatic reaction
deydrogenase
monooxygenase
enzymes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2009/067493
Other languages
German (de)
French (fr)
Other versions
WO2010070086A2 (en
Inventor
Harald GRÖGER
Edyta Burda
Ulrich Schwaneberg
Jan Marienhagen
Karlheinz Drauz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Evonik Degussa GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Degussa GmbH filed Critical Evonik Degussa GmbH
Publication of WO2010070086A2 publication Critical patent/WO2010070086A2/en
Publication of WO2010070086A3 publication Critical patent/WO2010070086A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention relates to a method for producing ketones by the enzymatic oxidation of alkanes, in which these alkanes are reacted in the presence of a monooxygenase, an alcohol deydrogenase and a cofactor suitable for both enzymes in an aqueous reaction medium in the presence of molecular oxygen.
PCT/EP2009/067493 2008-12-18 2009-12-18 Method for the enzymatic reaction of alkanes Ceased WO2010070086A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008054918.5 2008-12-18
DE102008054918A DE102008054918A1 (en) 2008-12-18 2008-12-18 Process for the enzymatic conversion of alkanes

Publications (2)

Publication Number Publication Date
WO2010070086A2 WO2010070086A2 (en) 2010-06-24
WO2010070086A3 true WO2010070086A3 (en) 2010-08-26

Family

ID=41816669

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/067493 Ceased WO2010070086A2 (en) 2008-12-18 2009-12-18 Method for the enzymatic reaction of alkanes

Country Status (2)

Country Link
DE (1) DE102008054918A1 (en)
WO (1) WO2010070086A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024004921A1 (en) * 2022-06-27 2024-01-04 天野エンザイム株式会社 Polypeptide, oxygenase, and use applications thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0088602A2 (en) * 1982-03-08 1983-09-14 Exxon Research And Engineering Company Microbiological oxidation process
WO2001007630A1 (en) * 1999-07-27 2001-02-01 Basf Aktiengesellschaft Novel cytochrome p450 monooxygenases and their use for oxidizing organic compounds
WO2001007574A2 (en) * 1999-07-27 2001-02-01 Basf Aktiengesellschaft Modified cytochrome p450 monooxygenases
WO2003008563A2 (en) * 2001-07-20 2003-01-30 California Institute Of Technology Improved cytochrome p450 oxygenases
WO2005017105A2 (en) * 2003-06-17 2005-02-24 California University Of Technology Regio- and enantioselective alkane hydroxylation with modified cytochrome p450
WO2007099051A1 (en) * 2006-03-02 2007-09-07 Wacker Chemie Ag Method for the production of ketones by oxygenating secondary alcohols with the aid of an alcohol dehydrogenase in the presence of a cofactor and an ketone as a cosubstrate

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4601893A (en) 1984-02-08 1986-07-22 Pfizer Inc. Laminate device for controlled and prolonged release of substances to an ambient environment and method of use
DE4014573C1 (en) 1990-05-07 1991-10-10 Forschungszentrum Juelich Gmbh, 5170 Juelich, De
DE4027453A1 (en) 1990-08-30 1992-03-05 Degussa NEW PLASMIDES FROM CORYNEBACTERIUM GLUTAMICUM AND DERIVED PLASMIDE VECTORS
DE4440118C1 (en) 1994-11-11 1995-11-09 Forschungszentrum Juelich Gmbh Gene expression in coryneform bacteria regulating DNA
JPH10229891A (en) 1997-02-20 1998-09-02 Mitsubishi Rayon Co Ltd Method for producing malonic acid derivative
DE10051175A1 (en) 2000-10-16 2002-05-02 Basf Ag Cytochrome P450 monoxygenases from thermophilic bacteria
DE10344594A1 (en) 2003-09-25 2005-05-12 Basf Ag Process for the preparation of cyclododecanone

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0088602A2 (en) * 1982-03-08 1983-09-14 Exxon Research And Engineering Company Microbiological oxidation process
WO2001007630A1 (en) * 1999-07-27 2001-02-01 Basf Aktiengesellschaft Novel cytochrome p450 monooxygenases and their use for oxidizing organic compounds
WO2001007574A2 (en) * 1999-07-27 2001-02-01 Basf Aktiengesellschaft Modified cytochrome p450 monooxygenases
WO2003008563A2 (en) * 2001-07-20 2003-01-30 California Institute Of Technology Improved cytochrome p450 oxygenases
WO2005017105A2 (en) * 2003-06-17 2005-02-24 California University Of Technology Regio- and enantioselective alkane hydroxylation with modified cytochrome p450
WO2007099051A1 (en) * 2006-03-02 2007-09-07 Wacker Chemie Ag Method for the production of ketones by oxygenating secondary alcohols with the aid of an alcohol dehydrogenase in the presence of a cofactor and an ketone as a cosubstrate

Also Published As

Publication number Publication date
DE102008054918A1 (en) 2010-07-01
WO2010070086A2 (en) 2010-06-24

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