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WO2010070086A3 - Procédé de conversion enzymatique d'alcanes - Google Patents

Procédé de conversion enzymatique d'alcanes Download PDF

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Publication number
WO2010070086A3
WO2010070086A3 PCT/EP2009/067493 EP2009067493W WO2010070086A3 WO 2010070086 A3 WO2010070086 A3 WO 2010070086A3 EP 2009067493 W EP2009067493 W EP 2009067493W WO 2010070086 A3 WO2010070086 A3 WO 2010070086A3
Authority
WO
WIPO (PCT)
Prior art keywords
alkanes
enzymatic reaction
deydrogenase
monooxygenase
enzymes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2009/067493
Other languages
German (de)
English (en)
Other versions
WO2010070086A2 (fr
Inventor
Harald GRÖGER
Edyta Burda
Ulrich Schwaneberg
Jan Marienhagen
Karlheinz Drauz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Evonik Degussa GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Degussa GmbH filed Critical Evonik Degussa GmbH
Publication of WO2010070086A2 publication Critical patent/WO2010070086A2/fr
Publication of WO2010070086A3 publication Critical patent/WO2010070086A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention concerne un procédé de production de cétones par oxydation enzymatique d'alcanes, consistant à faire réagir les alcanes en présence d'une mono-oxygénase, d'une alcool-déshydrogénase et d'un cofacteur adapté aux deux enzymes, dans un milieu réactionnel aqueux, en présence d'oxygène moléculaire.
PCT/EP2009/067493 2008-12-18 2009-12-18 Procédé de conversion enzymatique d'alcanes Ceased WO2010070086A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008054918.5 2008-12-18
DE102008054918A DE102008054918A1 (de) 2008-12-18 2008-12-18 Verfahren zur enzymatischen Umsetzung von Alkanen

Publications (2)

Publication Number Publication Date
WO2010070086A2 WO2010070086A2 (fr) 2010-06-24
WO2010070086A3 true WO2010070086A3 (fr) 2010-08-26

Family

ID=41816669

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/067493 Ceased WO2010070086A2 (fr) 2008-12-18 2009-12-18 Procédé de conversion enzymatique d'alcanes

Country Status (2)

Country Link
DE (1) DE102008054918A1 (fr)
WO (1) WO2010070086A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2024004921A1 (fr) * 2022-06-27 2024-01-04

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0088602A2 (fr) * 1982-03-08 1983-09-14 Exxon Research And Engineering Company Procédé microbiologique d'oxydation
WO2001007574A2 (fr) * 1999-07-27 2001-02-01 Basf Aktiengesellschaft Monooxygenases a cytochrome p450 modifiees
WO2001007630A1 (fr) * 1999-07-27 2001-02-01 Basf Aktiengesellschaft Monooxygenases a cytochrome p450 et leur utilisation pour l'oxydation de composes organiques
WO2003008563A2 (fr) * 2001-07-20 2003-01-30 California Institute Of Technology Cytochrome p450 oxygenases ameliorees
WO2005017105A2 (fr) * 2003-06-17 2005-02-24 California University Of Technology Hydroxylation d'alcane regio- et enantio-selective avec du cytochrome p450 modifie
WO2007099051A1 (fr) * 2006-03-02 2007-09-07 Wacker Chemie Ag Procédé de fabrication de cétones par oxydation d'alcools secondaires au moyen d'une alcool déshydrogénase en présence d'un cofacteur et d'une cétone en tant que cosubstrat

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4601893A (en) 1984-02-08 1986-07-22 Pfizer Inc. Laminate device for controlled and prolonged release of substances to an ambient environment and method of use
DE4014573C1 (fr) 1990-05-07 1991-10-10 Forschungszentrum Juelich Gmbh, 5170 Juelich, De
DE4027453A1 (de) 1990-08-30 1992-03-05 Degussa Neue plasmide aus corynebacterium glutamicum und davon abgeleitete plasmidvektoren
DE4440118C1 (de) 1994-11-11 1995-11-09 Forschungszentrum Juelich Gmbh Die Genexpression in coryneformen Bakterien regulierende DNA
JPH10229891A (ja) 1997-02-20 1998-09-02 Mitsubishi Rayon Co Ltd マロン酸誘導体の製造法
DE10051175A1 (de) 2000-10-16 2002-05-02 Basf Ag Cytochrom P450 Monoxygenasen aus thermophilen Bakterien
DE10344594A1 (de) 2003-09-25 2005-05-12 Basf Ag Verfahren zur Herstellung von Cyclododecanon

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0088602A2 (fr) * 1982-03-08 1983-09-14 Exxon Research And Engineering Company Procédé microbiologique d'oxydation
WO2001007574A2 (fr) * 1999-07-27 2001-02-01 Basf Aktiengesellschaft Monooxygenases a cytochrome p450 modifiees
WO2001007630A1 (fr) * 1999-07-27 2001-02-01 Basf Aktiengesellschaft Monooxygenases a cytochrome p450 et leur utilisation pour l'oxydation de composes organiques
WO2003008563A2 (fr) * 2001-07-20 2003-01-30 California Institute Of Technology Cytochrome p450 oxygenases ameliorees
WO2005017105A2 (fr) * 2003-06-17 2005-02-24 California University Of Technology Hydroxylation d'alcane regio- et enantio-selective avec du cytochrome p450 modifie
WO2007099051A1 (fr) * 2006-03-02 2007-09-07 Wacker Chemie Ag Procédé de fabrication de cétones par oxydation d'alcools secondaires au moyen d'une alcool déshydrogénase en présence d'un cofacteur et d'une cétone en tant que cosubstrat

Also Published As

Publication number Publication date
WO2010070086A2 (fr) 2010-06-24
DE102008054918A1 (de) 2010-07-01

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