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WO2008126752A1 - エクオール類を有効成分とする美白剤 - Google Patents

エクオール類を有効成分とする美白剤 Download PDF

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Publication number
WO2008126752A1
WO2008126752A1 PCT/JP2008/056663 JP2008056663W WO2008126752A1 WO 2008126752 A1 WO2008126752 A1 WO 2008126752A1 JP 2008056663 W JP2008056663 W JP 2008056663W WO 2008126752 A1 WO2008126752 A1 WO 2008126752A1
Authority
WO
WIPO (PCT)
Prior art keywords
skin
active ingredient
agent containing
lightening agent
containing equol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/056663
Other languages
English (en)
French (fr)
Inventor
Masayuki Nakano
Takashi Shibuya
Masaki Miyake
Norie Arai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hayashibara Seibutsu Kagaku Kenkyujo KK
Original Assignee
Hayashibara Seibutsu Kagaku Kenkyujo KK
Hayashibara Biochemical Laboratories Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hayashibara Seibutsu Kagaku Kenkyujo KK, Hayashibara Biochemical Laboratories Co Ltd filed Critical Hayashibara Seibutsu Kagaku Kenkyujo KK
Priority to JP2009509293A priority Critical patent/JPWO2008126752A1/ja
Priority to US12/595,390 priority patent/US20100280231A1/en
Priority to CN200880015520A priority patent/CN101677932A/zh
Priority to EP08739770A priority patent/EP2145615A1/en
Publication of WO2008126752A1 publication Critical patent/WO2008126752A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/163—Sugars; Polysaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/03—Organic compounds
    • A23L29/035—Organic compounds containing oxygen as heteroatom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
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    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Zoology (AREA)
  • Diabetes (AREA)
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  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)

Abstract

　新規な美白成分を有効成分とする美白剤を提供することを課題とし、エクオール、及び／又は、エクオールの水酸基にグリコシル基が１個又は２個以上結合したエクオール配糖体を有効成分とする美白剤を提供することにより上記課題を解決する。  
PCT/JP2008/056663 2007-04-09 2008-04-03 エクオール類を有効成分とする美白剤 Ceased WO2008126752A1 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2009509293A JPWO2008126752A1 (ja) 2007-04-09 2008-04-03 エクオール類を有効成分とする美白剤
US12/595,390 US20100280231A1 (en) 2007-04-09 2008-04-03 Whitening agent comprising equol or its saccharide derivative as an effective ingredient
CN200880015520A CN101677932A (zh) 2007-04-09 2008-04-03 以雌马酚类作为有效成分的美白剂
EP08739770A EP2145615A1 (en) 2007-04-09 2008-04-03 Skin-lightening agent containing equol compound as active ingredient

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007102164 2007-04-09
JP2007-102164 2007-04-09

Publications (1)

Publication Number Publication Date
WO2008126752A1 true WO2008126752A1 (ja) 2008-10-23

Family

ID=39863852

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/056663 Ceased WO2008126752A1 (ja) 2007-04-09 2008-04-03 エクオール類を有効成分とする美白剤

Country Status (7)

Country Link
US (1) US20100280231A1 (ja)
EP (1) EP2145615A1 (ja)
JP (2) JPWO2008126752A1 (ja)
KR (1) KR20100015996A (ja)
CN (1) CN101677932A (ja)
TW (1) TW200902077A (ja)
WO (1) WO2008126752A1 (ja)

Cited By (10)

* Cited by examiner, † Cited by third party
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JP2009161467A (ja) * 2007-12-28 2009-07-23 Lion Corp 痒み抑制剤および痒み抑制組成物
WO2012017911A1 (ja) 2010-08-03 2012-02-09 株式会社林原生物化学研究所 美白強化剤とその用途
CN102884429A (zh) * 2010-03-01 2013-01-16 系统生物股份有限公司 用于检测雌马酚的测试条
WO2013080260A1 (ja) 2011-11-30 2013-06-06 パナソニック株式会社 半導体装置及び表示装置
JP2015168668A (ja) * 2014-03-10 2015-09-28 株式会社ダイセル エクオールを含有する抗糖化剤
KR20160002116A (ko) 2014-06-30 2016-01-07 선문대학교 산학협력단 페녹소다이올 글루코사이드 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 약학적 조성물
JP2016196428A (ja) * 2015-04-03 2016-11-24 株式会社ダイセル エクオール及びキレート剤を含有する外用組成物
JP2016196427A (ja) * 2015-04-03 2016-11-24 株式会社ダイセル エクオール、酸化防止剤、及び油類を含有する外用組成物
WO2018207952A1 (ja) * 2017-05-12 2018-11-15 国立大学法人九州大学 発毛及び／又は育毛用組成物
JP2019523337A (ja) * 2016-08-01 2019-08-22 ザ プロクター アンド ギャンブル カンパニーＴｈｅ Ｐｒｏｃｔｅｒ ＆ Ｇａｍｂｌｅ Ｃｏｍｐａｎｙ 懸濁した粒子を含む相安定で噴霧可能なフレッシュニング組成物

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US20120156266A1 (en) * 2010-12-17 2012-06-21 Chong Jin Loy Compositions comprising lilium candidum extracts and uses thereof
US9421236B2 (en) 2010-12-17 2016-08-23 Johnson & Johnson Consumer Inc. Compositions comprising Lilium siberia extracts and uses thereof
US8481093B2 (en) 2010-12-17 2013-07-09 Johnson & Johnson Consumer Companies, Inc. Compositions comprising Lilium candidum extracts and uses thereof
EP2465518B1 (en) * 2010-12-17 2016-03-02 Johnson & Johnson Consumer Companies Inc. Compositions Comprising Lilium Candidum Extracts and Uses Thereof
US8883224B2 (en) 2011-03-28 2014-11-11 Mary Kay Inc. Topical skin care formulations comprising plant extracts
CN102784135B (zh) * 2012-07-05 2014-11-05 西安交通大学 基于雌马酚激活BKCa通道的应用
JP2014083020A (ja) * 2012-10-25 2014-05-12 Daicel Corp エクオールの精製方法
CN103053837B (zh) * 2012-12-28 2014-06-11 利川市五洲牧业有限责任公司 一种猪用促生长中草药饲料添加剂
FR3018821A1 (fr) 2014-03-24 2015-09-25 Agronomique Inst Nat Rech Nouveaux flavonoides o-alpha-glucosyles sur le cycle b, procede d'obtention et utilisations
TWI774660B (zh) * 2016-03-08 2022-08-21 日商大塚製藥股份有限公司 女性特有之身體及/或精神不快症狀之改善劑
US11097031B2 (en) 2016-08-01 2021-08-24 The Procter & Gamble Company Phase-stable, sprayable freshening compositions comprising suspended particles
WO2018026626A1 (en) * 2016-08-01 2018-02-08 The Procter & Gamble Company Phase-stable, sprayable freshening compositions comprising suspended particles and methods of freshening the air or a surface with the same
JP6541118B1 (ja) * 2018-04-27 2019-07-10 株式会社成和化成 化粧品基材および該化粧品基材を含有する毛髪用化粧品、美白剤
JP7672274B2 (ja) * 2021-04-20 2025-05-07 株式会社ノエビア ２層タイプ化粧水
KR20250059783A (ko) 2023-10-25 2025-05-07 한림대학교 산학협력단 에쿠올을 포함하는 지방간 질환의 예방 또는 치료용 약학적 조성물
WO2025179185A1 (en) * 2024-02-21 2025-08-28 Trustees Of Tufts College Water-resistant silk leather and related materials

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JP2001523258A (ja) 1997-05-01 2001-11-20 ノボゲン インコーポレイテッド 更年期症状および骨粗鬆症の治療または予防
JP2002511860A (ja) 1997-06-11 2002-04-16 シャーウッド エル． ゴルバッハ 皮膚の老化およびシワを治療および予防するためのイソフラボノイド
JP2002284664A (ja) 2001-03-29 2002-10-03 Shiseido Co Ltd 美白用皮膚外用剤
WO2003097037A1 (en) 2002-05-20 2003-11-27 Fuji Oil Company, Limited Allergic symptom reliever
JP2006504409A (ja) 2002-07-24 2006-02-09 チルドレンズ　ホスピタル　メディカル　センター 鏡像異性のエクオールを含有する組成物および製品、およびその製造方法
JP2006508942A (ja) * 2002-10-29 2006-03-16 コロラド　ステート　ユニバーシティー　リサーチ　ファウンデーション アンドロゲンによって仲介される疾患を治療するためのエクオールの使用

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