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WO2008011836A3 - Soluciones oftálmicas - Google Patents

Soluciones oftálmicas Download PDF

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Publication number
WO2008011836A3
WO2008011836A3 PCT/CR2007/000001 CR2007000001W WO2008011836A3 WO 2008011836 A3 WO2008011836 A3 WO 2008011836A3 CR 2007000001 W CR2007000001 W CR 2007000001W WO 2008011836 A3 WO2008011836 A3 WO 2008011836A3
Authority
WO
WIPO (PCT)
Prior art keywords
solutions
ophthalmic solutions
ophthalmic
artificial
advisable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CR2007/000001
Other languages
English (en)
French (fr)
Other versions
WO2008011836A2 (es
Inventor
Joaquina Faour
Ana C Pastini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Osmotica Costa Rica SA
Original Assignee
Osmotica Costa Rica SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osmotica Costa Rica SA filed Critical Osmotica Costa Rica SA
Priority to EP07817380A priority Critical patent/EP2070518A2/en
Priority to CA002658646A priority patent/CA2658646A1/en
Priority to MX2009000885A priority patent/MX2009000885A/es
Priority to BRPI0714587-0A priority patent/BRPI0714587A2/pt
Publication of WO2008011836A2 publication Critical patent/WO2008011836A2/es
Publication of WO2008011836A3 publication Critical patent/WO2008011836A3/es
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se revelan soluciones oftálmicas acuosas que contienen una combinación de ácido hialurónico o una sal farmacéuticamente aceptable del mismo, por. ej. hialuronato de sodio y alcohol polivinflico. Estas soluciones poseen un efecto sinérgico en la viscosidad y proveen una mejora estadísticamente significativa sobre las formulaciones del arte previo. tas soluciones se utilizan como lágrima artificial para el tratamiento del ojo seco y molestias oculares y pueden administrarse siempre que sea recomendable el uso de lágrimas artificiales. Las soluciones también son adecuadas para utilizar como vehículo para drogas oftálmicas.
PCT/CR2007/000001 2006-07-25 2007-07-24 Soluciones oftálmicas Ceased WO2008011836A2 (es)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP07817380A EP2070518A2 (en) 2006-07-25 2007-07-24 Ophthalmic solutions
CA002658646A CA2658646A1 (en) 2006-07-25 2007-07-24 Ophthalmic solutions
MX2009000885A MX2009000885A (es) 2006-07-25 2007-07-24 Soluciones oftalmicas.
BRPI0714587-0A BRPI0714587A2 (pt) 2006-07-25 2007-07-24 suluÇço oftÁlmica aquosa e uso da nesna

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83308306P 2006-07-25 2006-07-25
US60/833,083 2006-07-25

Publications (2)

Publication Number Publication Date
WO2008011836A2 WO2008011836A2 (es) 2008-01-31
WO2008011836A3 true WO2008011836A3 (es) 2008-07-31

Family

ID=38863092

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CR2007/000001 Ceased WO2008011836A2 (es) 2006-07-25 2007-07-24 Soluciones oftálmicas

Country Status (8)

Country Link
US (1) US20080050335A1 (es)
EP (1) EP2070518A2 (es)
KR (1) KR20090053892A (es)
AR (1) AR062046A1 (es)
BR (1) BRPI0714587A2 (es)
CA (1) CA2658646A1 (es)
MX (1) MX2009000885A (es)
WO (1) WO2008011836A2 (es)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200904485A (en) * 2007-05-18 2009-02-01 Alcon Res Ltd Phospholipid compositions for contact lens care and preservation of pharmaceutical compositions
MX2007010025A (es) * 2007-08-17 2009-02-25 Arturo Jimenez Bayardo Composición farmacéutica para tratamiento de hipertensión ocular.
MX2007011165A (es) * 2007-09-12 2009-03-11 Arturo Jimenez Bayardo Composición farmacéutica estable de timolol, dorzolamida y brimonidina.
EP2818184B1 (en) 2007-11-16 2018-10-31 Allergan, Inc. Compositions and methods for treating Purpura
US20090131303A1 (en) * 2007-11-16 2009-05-21 Bor-Shyue Hong Methods and compositions for treating dry eye
RU2600863C2 (ru) * 2007-12-10 2016-10-27 Сентисс Фарма Прайвит Лимитед Офтальмическая композиция, включающая фенилэфрин
CA2719666C (en) 2008-04-04 2016-08-16 Glenn Prestwich Alkylated semi-synthetic glycosaminoglycosan ethers, and methods for making and using thereof
WO2009142950A1 (en) * 2008-05-19 2009-11-26 Alcon Research, Ltd. Pharmaceutical compositions having carboxyvinyl polymer and povidone polymer
TW201010727A (en) * 2008-09-03 2010-03-16 Alcon Res Ltd Pharmaceutical composition having relatively low ionic strength
US20110257125A1 (en) * 2008-10-02 2011-10-20 Rolf Schaefer Mucomimetic compositions and uses therefore
US20100160342A1 (en) * 2008-12-22 2010-06-24 Alcon Research, Ltd. Compositions of Topical Ocular Solutions to Deliver Effective Concentrations of Active Agent to the Posterior Segment of the Eye
US20100278897A1 (en) * 2009-05-01 2010-11-04 Allergan, Inc. Intraocular bioactive agent delivery system with molecular partitioning system
EA025415B1 (ru) 2010-01-11 2016-12-30 Инотек Фармасьютикалз Корпорейшн Комбинация, набор и способ снижения внутриглазного давления
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
BR112012023421B1 (pt) 2010-03-17 2021-09-14 Novaliq Gmbh Composição farmacêutica para tratamento de aumento de pressão intraocular
EP2569325A4 (en) 2010-03-26 2013-10-09 Inotek Pharmaceuticals Corp METHOD FOR REDUCING INNER EYE PRESSURE IN HUMANS USING N6-CYCLOPENTYLADENOSINE (CPA), CPA DERIVATIVES OR PRODRUGS THEREOF
JP2013523828A (ja) * 2010-04-07 2013-06-17 アラーガン インコーポレイテッド 眼科用組成物のための保存剤の組み合わせ
EP2462921A1 (en) 2010-11-11 2012-06-13 Novaliq GmbH Liquid pharmaceutical compositions for the treatment of a posterior eye disease
KR101119610B1 (ko) * 2010-12-02 2012-03-06 한림제약(주) 도르졸라미드, 티몰롤 및 브리모니딘을 포함하는 안과용 액제 조성물
EP2688402B1 (en) 2011-03-23 2018-10-24 University of Utah Research Foundation Means for treating or preventing urological inflammation
PL2714010T3 (pl) 2011-05-25 2017-08-31 Novaliq Gmbh Kompozycja farmaceutyczna do miejscowego stosowania oparta na semifluorowanych alkanach
EA201301332A1 (ru) * 2011-05-27 2014-06-30 Рациофарм Гмбх ОФТАЛЬМОЛОГИЧЕСКИЙ ПРЕПАРАТ, СОДЕРЖАЩИЙ АНАЛОГ PGF2α
TW201309306A (zh) * 2011-06-23 2013-03-01 參天製藥股份有限公司 含有玻尿酸或其鹽及丙二醇之點眼液
DK2800573T3 (da) * 2012-01-08 2021-06-28 Medicure Tech Ltd Oftalmologisk sammensætning
US9278991B2 (en) 2012-01-26 2016-03-08 Inotek Pharmaceuticals Corporation Anhydrous polymorphs of [(2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)} methyl nitrate and processes of preparation thereof
FR2991876B1 (fr) 2012-06-13 2014-11-21 Vivacy Lab Composition, en milieu aqueux, comprenant au moins un acide hyaluronique et au moins un sel hydrosoluble de sucrose octasulfate
CA3142049C (en) * 2012-09-12 2023-08-29 Novaliq Gmbh Semifluorinated alkane compositions
CA2997744C (en) 2012-09-12 2019-12-31 Novaliq Gmbh Compositions comprising mixtures of semifluorinated alkanes
CN102885767A (zh) * 2012-11-02 2013-01-23 江苏吉贝尔药业有限公司 一种新的盐酸奥洛他定滴眼液及其制备方法
WO2014117010A2 (en) * 2013-01-24 2014-07-31 Rigel Pharmaceuticals, Inc. Composition for ophthalmic administration
DK3517100T3 (da) * 2013-02-01 2020-12-14 Allergan Inc Kunstige tårer omfattende natriumhyaluronat og carboxymethylcellulose
KR101412776B1 (ko) 2013-03-11 2014-07-01 가톨릭대학교 산학협력단 각결막염 치료용 점안제 조성물 및 이의 제조 방법
CA2903114A1 (en) * 2013-03-15 2014-09-25 Inotek Pharmaceuticals Corporation Ophthalmic formulations
US9907750B2 (en) 2013-03-19 2018-03-06 Senju Pharmaceutical Co., Ltd. Two-layer separation-type eye drop containing squalane
US9492474B2 (en) 2013-07-10 2016-11-15 Matrix Biology Institute Compositions of hyaluronan with high elasticity and uses thereof
JP6452725B2 (ja) * 2014-05-01 2019-01-16 インテグラル バイオシステムズ エルエルシー 眼疾患の治療のための膜付着性の自己組織化システム
CN104069118B (zh) * 2014-07-01 2016-08-24 武汉五景药业有限公司 滴眼液及其制备方法
UA124698C2 (uk) * 2014-10-20 2021-11-03 Сентіс Фарма Прайвет Лімітед Офтальмологічний розчин
US10751337B2 (en) * 2015-02-24 2020-08-25 Ocugen, Inc. Preservative free ocular compositions and methods for using the same for treating dry eye disease and other eye disorders
US9877964B2 (en) 2015-02-24 2018-01-30 Ocugen, Inc. Methods and compositions for treating dry eye disease and other eye disorders
AU2016222902A1 (en) * 2015-02-24 2017-08-31 Ocugen, Inc. Methods and compositions for treating dry eye disease and other eye disorders
ES2827426T3 (es) * 2015-03-26 2021-05-21 Dmg Italia Srl Composición oftálmica para la protección corneal
CN106256351A (zh) * 2015-06-18 2016-12-28 江苏吉贝尔药业股份有限公司 盐酸奥洛他定凝胶滴眼液及其制备方法
ITUB20152542A1 (it) * 2015-07-28 2017-01-28 Altergon Sa Formulati oftalmici a base di complessi cooperativi di acido ialuronico a basso e alto peso molecolare
CN108350395A (zh) 2015-09-03 2018-07-31 杜兰教育基金委员会 多用途消毒和灭菌溶液的组合物和方法
US11452732B2 (en) 2015-09-05 2022-09-27 Randal Davis Homogeneous ophthalmic composition
US10130639B1 (en) * 2015-09-05 2018-11-20 Randal Davis Homogeneous ophthalmic composition
PT3842047T (pt) 2015-09-24 2024-09-19 Matrix Biology Inst Composições de hialuronano de elevada elasticidade e processos para o seu uso
WO2017055454A1 (en) 2015-09-30 2017-04-06 Novaliq Gmbh Semifluorinated compounds and their compositions
DK3356313T3 (da) 2015-09-30 2020-07-20 Novaliq Gmbh 2-perfluorhexyloktan til oftalmisk indgivelse
ITUB20160876A1 (it) * 2016-02-19 2017-08-19 Dambrosio Enzo Maria Combinazione di un agente antiallergico con un antagonista muscarinico e/o un agonista dopaminergico per l'uso in prevenzione/ arresto di miopia assiale nell’uomo
AR108280A1 (es) * 2016-05-05 2018-08-08 Acraf Composición oftálmica que comprende una combinación sinérgica de glucógeno y ácido hialurónico o sal del mismo
JP2019520357A (ja) 2016-06-23 2019-07-18 ノバリック ゲーエムベーハー 局所投与方法
CN116726006A (zh) * 2016-08-19 2023-09-12 阿拉西斯医药公司 眼科药物组合物及其相关用途
US11337994B2 (en) 2016-09-15 2022-05-24 University Of Utah Research Foundation In situ gelling compositions for the treatment or prevention of inflammation and tissue damage
WO2018054932A1 (en) 2016-09-22 2018-03-29 Novaliq Gmbh Pharmaceutical compositions for use in the therapy of blepharitis
CN109906085B (zh) 2016-09-23 2024-03-08 诺瓦利克有限责任公司 含有环孢素的眼用组合物
KR101819709B1 (ko) 2017-01-13 2018-01-17 (주)아이엠디팜 설글리코타이드 또는 이의 약학적으로 허용가능한 염을 포함하는 안구건조증의 예방 또는 치료용 약학 조성물
IT201700009786A1 (it) * 2017-01-30 2018-07-30 For Health Pharma S R L Sostituto lacrimale
PL3612228T3 (pl) 2017-04-21 2024-04-08 Dermaliq Therapeutics, Inc. Kompozycje jodu
US11278503B2 (en) 2017-05-12 2022-03-22 Novaliq Gmbh Pharmaceutical compositions comprising semifluorinated alkanes for the treatment of contact lense-related conditions
WO2018212846A1 (en) 2017-05-19 2018-11-22 Ocugen, Inc. Ophthalmic compositions and methods of use
CN109276715A (zh) * 2017-07-20 2019-01-29 西安力邦医药科技有限责任公司 高保湿性的抗过敏鼻用药物组合物、其制备方法和应用
SG11202002640YA (en) 2017-09-27 2020-04-29 Novaliq Gmbh Ophthalmic compositions comprising latanoprost for use in the treatment of ocular diseases
US11896559B2 (en) 2017-10-04 2024-02-13 Novaliq Gmbh Opthalmic compositions comprising F6H8
CA3091308A1 (en) 2018-03-02 2019-09-06 Novaliq Gmbh Pharmaceutical compositions comprising nebivolol
WO2019202017A1 (en) 2018-04-18 2019-10-24 i.com medical GmbH High molecular weight hyaluronic acid for treatment and prevention of severe ocular surface disease
EP3781116A1 (en) * 2018-04-18 2021-02-24 i.com Medical GmbH High molecular weight hyaluronic acid for enhancing epithelial survival and reconstitution of body surfaces
WO2019206956A1 (en) 2018-04-27 2019-10-31 Novaliq Gmbh Ophthalmic compositions comprising tafluprost for the treatment of glaucoma
CN110604812B (zh) * 2018-06-14 2023-01-31 陕西慧康生物科技有限责任公司 一种含有重组人溶菌酶的人工泪液
CN110787126A (zh) * 2018-08-03 2020-02-14 武汉武药科技有限公司 一种盐酸莫西沙星眼用凝胶及其制备方法
MY206642A (en) 2018-10-12 2024-12-30 Novaliq Gmbh Ophthalmic composition for treatment of dry eye disease
CN111228653A (zh) 2018-11-13 2020-06-05 格莱科米拉治疗公司 用电离辐射加强癌症治疗的方法
US12268706B2 (en) 2019-01-31 2025-04-08 i.com medical GmbH Hyaluronic acid for relief of idiopathic ocular pain
US12397039B2 (en) 2019-02-13 2025-08-26 Novaliq Gmbh Compositions and methods for the treatment of ocular neovascularization
CN110151690A (zh) * 2019-07-03 2019-08-23 上海美哈医药科技有限公司 一种眼部护理洗眼液及其制备方法
US20210000910A1 (en) 2019-07-03 2021-01-07 Jysk Skin Solutions Pte Ltd Topical compositions
AU2020340561A1 (en) 2019-09-06 2022-03-31 Novaliq Gmbh Ophthalmic composition for the treatment of uveitis
GR1010024B (el) * 2020-05-06 2021-06-01 Φαρματεν Α.Β.Ε.Ε. Φαρμακευτικο σκευασμα ελευθερο συντηρητικου για οφθαλμικη χορηγηση που περιλαμβανει βριμονιδινη
US11696910B2 (en) 2021-07-23 2023-07-11 Somerset Therapeutics, Llc Buffer-free, stable ophthalmological compositions of ketorolac and phenylephrine and applications thereof
US12029729B2 (en) 2021-07-23 2024-07-09 Somerset Therapeutics, Llc Chelated, stable ophthalmological compositions of ketorolac and phenylephrine and applications thereof
CN113952506B (zh) * 2021-09-26 2023-03-21 华南理工大学 一种仿生软骨表层修复水凝胶的制备方法
US11951123B2 (en) 2022-01-12 2024-04-09 Platform Ophthalmic Innovations, LLC Fortified nutritional lubricating drops for dry eye disease
US12397017B2 (en) 2022-01-12 2025-08-26 Platform Ophthalmic Innovations, LLC Fortified nutritional lubricating drops for dry eye disease
US12083204B2 (en) 2022-06-02 2024-09-10 L'oreal Topical composition for homeostatic delivery of nitric oxide and uses thereof
EP4309644A1 (en) * 2022-07-22 2024-01-24 Warszawskie Zaklady Farmaceutyczne Polfa S.A. Preservative-free ophthalmic composition comprising an antiglaucoma agent
WO2025230326A1 (ko) * 2024-04-30 2025-11-06 주식회사태준제약 필로카르핀을 포함하는 점안 조성물

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004062660A1 (en) * 2003-01-08 2004-07-29 Advanced Medical Optics Inc. Contact lens and eye drop rewetter compositions and their uses
US20050148542A1 (en) * 2000-12-20 2005-07-07 Shah Mandar V. Intraocular irrigating solution having improved flow characteristics

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3679804A (en) * 1969-05-01 1972-07-25 Geigy Chem Corp Method for treating glaucoma with alkyl gallates
US4677115A (en) * 1984-12-12 1987-06-30 Merck & Co., Inc. Antiglaucoma thieno-thiopyran and thieno-thiepin sulfonamide derivatives, compositions, and method of use thereof
EP0323522A4 (en) 1987-07-07 1989-08-30 Santen Pharmaceutical Co Ltd ARTIFICIAL TEAR.
US5461081A (en) * 1989-09-28 1995-10-24 Alcon Laboratories, Inc. Topical ophthalmic pharmaceutical vehicles
JPH05503527A (ja) 1990-02-22 1993-06-10 マクノート・ピーティーワイ・リミテッド 人工涙液
JP3050898B2 (ja) 1990-07-06 2000-06-12 千寿製薬株式会社 水性医薬製剤
JP3310994B2 (ja) 1991-07-03 2002-08-05 電気化学工業株式会社 アレルギー治療剤
US5563171A (en) * 1993-11-05 1996-10-08 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists
IT1273011B (it) * 1994-07-25 1997-07-01 Trhecnopharma S A Preparato oftalmico per l'uso come lacrima artificiale
US5674876A (en) * 1995-01-20 1997-10-07 Research Development Foundation ρ-heteroatom-substituted phenols and uses thereof
US20030086986A1 (en) * 1998-08-06 2003-05-08 Bruijn Chris De Ophthalmic, pharmaceutical and other healthcare preparations with naturally occurring plant compounds, extracts and derivatives
AU1180300A (en) * 1998-11-16 2000-06-05 Rohto Pharmaceutical Co., Ltd. Liquid ophthalmic preparations
IT1306123B1 (it) * 1999-04-02 2001-05-30 Technopharma Sa Soluzione oftalmica viscosizzata con azione detergente sulle lenti acontatto.
RU2163123C2 (ru) 1999-05-26 2001-02-20 Уфимский научно-исследовательский институт глазных болезней Глазные капли
JP2002020279A (ja) 2000-06-30 2002-01-23 Taisho Pharmaceut Co Ltd 点眼液
WO2002044276A2 (en) * 2000-11-28 2002-06-06 Focal, Inc. Polyalkylene glycol viscosity-enhancing polymeric formulations
JP3455852B2 (ja) 2000-12-26 2003-10-14 株式会社オフテクス 洗眼液組成物
PE20030263A1 (es) 2001-07-31 2003-04-17 Novartis Ag Composicion farmaceutica oftalmica
DE10161110A1 (de) 2001-12-12 2003-06-26 Ursapharm Arzneimittel Gmbh Pharmazeutische Zusammensetzung zur ophthalmologischen und rhinologischen Anwendung
US7045121B2 (en) * 2001-12-14 2006-05-16 Allergan, Inc. Ophthalmic compositions for lubricating eyes and methods for making and using same
GB0130603D0 (en) * 2001-12-20 2002-02-06 Renaissance Healthcare Europ L Improvements in or relating to ophthalmic solutions
KR20110134525A (ko) 2003-06-13 2011-12-14 알콘, 인코퍼레이티드 시너지성의 2개의 폴리머 배합물을 포함하는 안과용 조성물
TWI336257B (en) 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
JP2005187354A (ja) 2003-12-25 2005-07-14 Lion Corp 水性外用剤組成物
US20050202097A1 (en) * 2004-03-12 2005-09-15 Melbj Holdings, Llc, Florida Lubricant for the ocular surface
US8288362B2 (en) * 2004-05-07 2012-10-16 S.K. Pharmaceuticals, Inc. Stabilized glycosaminoglycan preparations and related methods
CA2565944C (en) 2004-05-07 2011-07-19 S.K. Pharmaceuticals, Inc. Stabilized hyaluronan preparations and related methods

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050148542A1 (en) * 2000-12-20 2005-07-07 Shah Mandar V. Intraocular irrigating solution having improved flow characteristics
WO2004062660A1 (en) * 2003-01-08 2004-07-29 Advanced Medical Optics Inc. Contact lens and eye drop rewetter compositions and their uses

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WO2008011836A2 (es) 2008-01-31
KR20090053892A (ko) 2009-05-28
US20080050335A1 (en) 2008-02-28
CA2658646A1 (en) 2008-01-31
EP2070518A2 (en) 2009-06-17
AR062046A1 (es) 2008-08-10
BRPI0714587A2 (pt) 2013-05-07

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