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WO2008093647A1 - Microréseau, son procédé de fabrication, et procédé de détection d'une interaction entre une molécule organique et une substance active - Google Patents

Microréseau, son procédé de fabrication, et procédé de détection d'une interaction entre une molécule organique et une substance active Download PDF

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Publication number
WO2008093647A1
WO2008093647A1 PCT/JP2008/051227 JP2008051227W WO2008093647A1 WO 2008093647 A1 WO2008093647 A1 WO 2008093647A1 JP 2008051227 W JP2008051227 W JP 2008051227W WO 2008093647 A1 WO2008093647 A1 WO 2008093647A1
Authority
WO
WIPO (PCT)
Prior art keywords
microarray
organic molecule
interaction
active substance
immobilized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/051227
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English (en)
Japanese (ja)
Inventor
Masato Oikawa
Makoto Sasaki
Yuichi Ogawa
Shin'ichiro Hayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tohoku University NUC
Original Assignee
Tohoku University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tohoku University NUC filed Critical Tohoku University NUC
Priority to JP2008556090A priority Critical patent/JPWO2008093647A1/ja
Publication of WO2008093647A1 publication Critical patent/WO2008093647A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3581—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using far infrared light; using Terahertz radiation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/251—Colorimeters; Construction thereof
    • G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3563—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing solids; Preparation of samples therefor

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

L'invention concerne un microréseau sur lequel est immobilisée une molécule organique, qui permet à la molécule organique d'être immobilisée sur un substrat solide dans diverses orientations et de détecter une interaction compliquée entre la molécule organique et une substance active mais n'a pas de restriction d'orientation et qui, par conséquent, peut analyser des relations structure-activité et être fabriqué de façon simple et à bas prix ; un procédé de fabrication du microréseau ; et un procédé de détection de l'interaction entre une substance active et la molécule organique à l'aide du microréseau. L'invention concerne spécifiquement un microréseau sur lequel est immobilisée une molécule organique utilisée pour la détection de l'interaction entre la molécule organique et la substance active. Le microréseau comprend un substrat (A), un support organique (B) immobilisé sur le substrat (A) par une interaction intermoléculaire, et une molécule organique (C) immobilisée sur le support organique (B). Dans un mode de réalisation préféré, une analyse est faite par la mesure à l'aide du microréseau d'au moins un élément choisi parmi la transmission, la réflexion et l'interférence d'une onde Téra-Hertz (THz).
PCT/JP2008/051227 2007-01-31 2008-01-28 Microréseau, son procédé de fabrication, et procédé de détection d'une interaction entre une molécule organique et une substance active Ceased WO2008093647A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008556090A JPWO2008093647A1 (ja) 2007-01-31 2008-01-28 マイクロアレイとその製造方法並びに有機分子と作用物質との相互作用の検出方法

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007022396 2007-01-31
JP2007-022396 2007-01-31
JP2007022380 2007-01-31
JP2007-022380 2007-01-31

Publications (1)

Publication Number Publication Date
WO2008093647A1 true WO2008093647A1 (fr) 2008-08-07

Family

ID=39673958

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/051227 Ceased WO2008093647A1 (fr) 2007-01-31 2008-01-28 Microréseau, son procédé de fabrication, et procédé de détection d'une interaction entre une molécule organique et une substance active

Country Status (2)

Country Link
JP (1) JPWO2008093647A1 (fr)
WO (1) WO2008093647A1 (fr)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010190837A (ja) * 2009-02-20 2010-09-02 Kurabo Ind Ltd ｌｏｇＰの決定方法、および該方法に使用される二相系溶媒
JP2010249564A (ja) * 2009-04-13 2010-11-04 Nippon Telegr & Teleph Corp <Ntt> 溶解性分光測定方法及び溶解性分光測定装置
JP2011506673A (ja) * 2007-12-14 2011-03-03 バイオティウム， インコーポレイテッド 蛍光性化合物
JP2011112548A (ja) * 2009-11-27 2011-06-09 Sony Corp 生体サンプル解析方法、生体サンプル解析装置及び生体サンプル解析プログラム
WO2011125355A1 (fr) * 2010-04-01 2011-10-13 株式会社村田製作所 Procédé de mesure d'une caractéristique d'un objet à mesurer, et dispositif de détection utilisé dans ledit procédé
CN108398400A (zh) * 2018-01-18 2018-08-14 河南工业大学 利用太赫兹成像无损检测小麦中脂肪酸含量的方法
JP2020511652A (ja) * 2016-12-01 2020-04-16 ユニバーシティ・オブ・ソウル・インダストリー・コーオパレイション・ファウンデイションＵｎｉｖｅｒｓｉｔｙ Ｏｆ Ｓｅｏｕｌ Ｉｎｄｕｓｔｒｙ Ｃｏｏｐｅｒａｔｉｏｎ Ｆｏｕｎｄａｔｉｏｎ テラヘルツ波を用いたｄｎａ分析方法およびｄｎａ分析装置
WO2020080576A1 (fr) * 2018-10-18 2020-04-23 연세대학교 산학협력단 Procédé permettant de prédire un changement d'absorbance au moyen d'une interaction intermoléculaire
CN111366555A (zh) * 2020-02-27 2020-07-03 浙江大学 一种耕地土壤中农膜残留的检测方法
WO2022029135A1 (fr) * 2020-08-03 2022-02-10 Jt International Sa Procédé de mesure et étiquette disposée dans un article à fumer ou un emballage d'articles à fumer

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11201971A (ja) * 1997-11-09 1999-07-30 Bayer Corp 流体試料中の分析対象物を検出する方法
JP2005233955A (ja) * 2004-02-16 2005-09-02 Samsung Electronics Co Ltd 生体分子を固体基板上に非共有的に固定化する方法及びそれによって製造されるマイクロアレイ
JP2005283143A (ja) * 2004-03-26 2005-10-13 Fuji Photo Film Co Ltd バイオセンサー
JP2006084422A (ja) * 2004-09-17 2006-03-30 Pentax Corp 透過画像生成方法及び透過画像生成装置
WO2006137824A2 (fr) * 2004-08-04 2006-12-28 Intel Corporation Procedes et systemes de detection d'une liaison biomoleculaire au moyen d'un rayonnement terahertz

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11201971A (ja) * 1997-11-09 1999-07-30 Bayer Corp 流体試料中の分析対象物を検出する方法
JP2005233955A (ja) * 2004-02-16 2005-09-02 Samsung Electronics Co Ltd 生体分子を固体基板上に非共有的に固定化する方法及びそれによって製造されるマイクロアレイ
JP2005283143A (ja) * 2004-03-26 2005-10-13 Fuji Photo Film Co Ltd バイオセンサー
WO2006137824A2 (fr) * 2004-08-04 2006-12-28 Intel Corporation Procedes et systemes de detection d'une liaison biomoleculaire au moyen d'un rayonnement terahertz
JP2006084422A (ja) * 2004-09-17 2006-03-30 Pentax Corp 透過画像生成方法及び透過画像生成装置

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9791450B2 (en) 2007-12-14 2017-10-17 Biotium, Inc. Fluorescent compounds
JP2011506673A (ja) * 2007-12-14 2011-03-03 バイオティウム， インコーポレイテッド 蛍光性化合物
US9097667B2 (en) 2007-12-14 2015-08-04 Biotium, Inc. Fluorescent compounds
JP2015172199A (ja) * 2007-12-14 2015-10-01 バイオティウム， インコーポレイテッド 蛍光性化合物
JP2010190837A (ja) * 2009-02-20 2010-09-02 Kurabo Ind Ltd ｌｏｇＰの決定方法、および該方法に使用される二相系溶媒
JP2010249564A (ja) * 2009-04-13 2010-11-04 Nippon Telegr & Teleph Corp <Ntt> 溶解性分光測定方法及び溶解性分光測定装置
JP2011112548A (ja) * 2009-11-27 2011-06-09 Sony Corp 生体サンプル解析方法、生体サンプル解析装置及び生体サンプル解析プログラム
WO2011125355A1 (fr) * 2010-04-01 2011-10-13 株式会社村田製作所 Procédé de mesure d'une caractéristique d'un objet à mesurer, et dispositif de détection utilisé dans ledit procédé
JP5859955B2 (ja) * 2010-04-01 2016-02-16 株式会社村田製作所 被測定物の特性の測定方法、および、それに用いられるセンシングデバイス
JP2020511652A (ja) * 2016-12-01 2020-04-16 ユニバーシティ・オブ・ソウル・インダストリー・コーオパレイション・ファウンデイションＵｎｉｖｅｒｓｉｔｙ Ｏｆ Ｓｅｏｕｌ Ｉｎｄｕｓｔｒｙ Ｃｏｏｐｅｒａｔｉｏｎ Ｆｏｕｎｄａｔｉｏｎ テラヘルツ波を用いたｄｎａ分析方法およびｄｎａ分析装置
CN108398400A (zh) * 2018-01-18 2018-08-14 河南工业大学 利用太赫兹成像无损检测小麦中脂肪酸含量的方法
CN108398400B (zh) * 2018-01-18 2020-12-22 河南工业大学 利用太赫兹成像无损检测小麦中脂肪酸含量的方法
WO2020080576A1 (fr) * 2018-10-18 2020-04-23 연세대학교 산학협력단 Procédé permettant de prédire un changement d'absorbance au moyen d'une interaction intermoléculaire
CN111366555A (zh) * 2020-02-27 2020-07-03 浙江大学 一种耕地土壤中农膜残留的检测方法
CN111366555B (zh) * 2020-02-27 2021-01-26 浙江大学 一种耕地土壤中农膜残留的检测方法
WO2022029135A1 (fr) * 2020-08-03 2022-02-10 Jt International Sa Procédé de mesure et étiquette disposée dans un article à fumer ou un emballage d'articles à fumer

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