[go: up one dir, main page]

WO2004005346A3 - Human nuclear hormone receptor - Google Patents

Human nuclear hormone receptor Download PDF

Info

Publication number
WO2004005346A3
WO2004005346A3 PCT/GB2003/002848 GB0302848W WO2004005346A3 WO 2004005346 A3 WO2004005346 A3 WO 2004005346A3 GB 0302848 W GB0302848 W GB 0302848W WO 2004005346 A3 WO2004005346 A3 WO 2004005346A3
Authority
WO
WIPO (PCT)
Prior art keywords
hormone receptor
nuclear hormone
human nuclear
protein
termed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2003/002848
Other languages
French (fr)
Other versions
WO2004005346A2 (en
WO2004005346A8 (en
Inventor
Christopher Benjamin Phelps
Richard Joseph Fagan
Janet Marjorie Allen
Kathryn Elizabeth Allen
Ilana Stancovski
Valerie Nathalie Pierron
Tom Phillips
Caroline Ann Hunt
Zinat Ellaheh Enayat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inpharmatica Ltd
Original Assignee
Inpharmatica Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inpharmatica Ltd filed Critical Inpharmatica Ltd
Priority to AU2003244831A priority Critical patent/AU2003244831A1/en
Priority to EP03738307A priority patent/EP1520023A2/en
Publication of WO2004005346A2 publication Critical patent/WO2004005346A2/en
Publication of WO2004005346A8 publication Critical patent/WO2004005346A8/en
Publication of WO2004005346A3 publication Critical patent/WO2004005346A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

This invention relates to the protein, termed BAB13403.1, herein identified as containing a Nuclear Hormone Receptor Ligand Binding Domain and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease.
PCT/GB2003/002848 2002-07-03 2003-07-03 Human nuclear hormone receptor Ceased WO2004005346A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2003244831A AU2003244831A1 (en) 2002-07-03 2003-07-03 Human nuclear hormone receptor
EP03738307A EP1520023A2 (en) 2002-07-03 2003-07-03 Human nuclear hormone receptor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0215406.0 2002-07-03
GB0215406A GB0215406D0 (en) 2002-07-03 2002-07-03 Protein

Publications (3)

Publication Number Publication Date
WO2004005346A2 WO2004005346A2 (en) 2004-01-15
WO2004005346A8 WO2004005346A8 (en) 2004-03-25
WO2004005346A3 true WO2004005346A3 (en) 2004-04-29

Family

ID=9939789

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2003/002848 Ceased WO2004005346A2 (en) 2002-07-03 2003-07-03 Human nuclear hormone receptor

Country Status (4)

Country Link
EP (1) EP1520023A2 (en)
AU (1) AU2003244831A1 (en)
GB (1) GB0215406D0 (en)
WO (1) WO2004005346A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000058473A2 (en) * 1999-03-31 2000-10-05 Curagen Corporation Nucleic acids including open reading frames encoding polypeptides; 'orfx'
WO2002070539A2 (en) * 2001-03-05 2002-09-12 Hyseq, Inc. Novel nucleic acids and polypeptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000058473A2 (en) * 1999-03-31 2000-10-05 Curagen Corporation Nucleic acids including open reading frames encoding polypeptides; 'orfx'
WO2002070539A2 (en) * 2001-03-05 2002-09-12 Hyseq, Inc. Novel nucleic acids and polypeptides

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 11 September 1997 (1997-09-11), NCI-CGAP: "nl50d03.s1 NCI_CGAP_Pr4 Homo sapiens cDNA clone IMAGE: 1044101, mRNA sequence", XP002268262, Database accession no. AA558357 *
DATABASE EMBL [online] 18 April 1997 (1997-04-18), ADAMS, M.D. ET AL.: "EST96990 Testis I Homo sapiens cDNA 5' end", XP002268263, Database accession no. AA383339 *
DATABASE EMBL [online] 20 January 2003 (2003-01-20), "Human polynucleotide SEQ ID NO: 648", XP002268260, Database accession no. ABZ11766 *
DATABASE EMBL [online] 20 January 2003 (2003-01-20), "Human polypeptide SEQ ID NO: 1596", XP002268261, Database accession no. ABP69549 *
DATABASE NCBI PROTEIN DATABASE [online] 22 February 2001 (2001-02-22), NAGASE, T. ET AL.: "KIAA1577 protein [Homo sapiens]", XP002268259, Database accession no. BAB13403 *
EGEA, P.F. ET AL.: "Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid", EMBO JOURNAL, vol. 19, no. 11, 1 June 2000 (2000-06-01), pages 2592 - 2601, XP002268433 *
EGEA, P.F. ET AL.: "Molecular Recognition of Agonist Ligands by RXRs", MOLECULAR ENDOCRINOLOGY, vol. 16, no. 5, May 2002 (2002-05-01), pages 987 - 997, XP002268434 *
NAGASE, T. ET AL.: "Predicton of the Coding Sequences of Unidentified Human Genes. XVIII. The Complete Sequences of 100 New cDNA Clones from Brain Which Code for Large Proteins in vitro", DNA RESEARCH, vol. 7, no. 4, 31 August 2000 (2000-08-31), pages 273 - 281, XP001012454 *

Also Published As

Publication number Publication date
EP1520023A2 (en) 2005-04-06
GB0215406D0 (en) 2002-08-14
AU2003244831A1 (en) 2004-01-23
AU2003244831A8 (en) 2004-01-23
WO2004005346A2 (en) 2004-01-15
WO2004005346A8 (en) 2004-03-25

Similar Documents

Publication Publication Date Title
WO2003054012A3 (en) Leptin proteins
WO2004081199A3 (en) Novel compositions and methods for the treatment of immune related disease
WO2004096856A3 (en) Secreted protein family
WO2002070563A3 (en) Nuclear hormone receptor ligand binding domain
WO2006046073A3 (en) C1q related protein
WO2004005346A3 (en) Human nuclear hormone receptor
WO2002070558A3 (en) Nuclear hormone receptor ligand binding domain
WO2004003010A3 (en) Nuclear hormone receptor ligano-binding domain containing protein
WO2001014415A3 (en) Egfh2 genes and gene products
WO2004101618A3 (en) Progestin-yol002c-cgi-45 receptor-related proteins
WO2004050703A8 (en) Splice variant of the human pituitary growth hormone
WO2004003011A3 (en) Nuclear hormone receptor
WO2001064875A3 (en) Human transporter genes and proteins encoded thereby
WO2006043060A3 (en) Mam domain containing protein
WO2004009633A8 (en) Serotonin receptor
WO2004056983A3 (en) Metalloprotease proteins
WO2002101394A3 (en) Screening method which uses bnpi and dnpi
WO2004000882A3 (en) Proteins
WO2005085285A3 (en) Nuclear hormone receptors
WO2004056863A3 (en) Splice variant of human placental growth hormone
WO2002033058A3 (en) Novel cysteine proteases and uses thereof
WO2002046380A3 (en) Protein kinase
WO2003100061A3 (en) Three finger toxin fold proteins
WO2004024762A3 (en) Il-8 like protein
WO2004016654A8 (en) Il-8 like protein

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
CFP Corrected version of a pamphlet front page
CR1 Correction of entry in section i

Free format text: IN PCT GAZETTE 03/2004 REPLACE "(71) APPLICANT (FOR US ONLY)" BY "(72) INVENTOR; AND (75) INVENTOR/APPLICANT (FOR US ONLY)"; UNDER (72, 75) IN THE ADDRESS OF "FAGAN, RICHARD, JOSEPH" REPLACE "IMPHARMATICA LIMITED" BY "INPHARMATICA LIMITED"

WWE Wipo information: entry into national phase

Ref document number: 2003738307

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2003738307

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 2003738307

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP