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WO2004078178B1 - Composes de buprenorphine pour le traitement de la dependance a l'alcool et de la consommation excessive d'alcool - Google Patents

Composes de buprenorphine pour le traitement de la dependance a l'alcool et de la consommation excessive d'alcool

Info

Publication number
WO2004078178B1
WO2004078178B1 PCT/SE2004/000293 SE2004000293W WO2004078178B1 WO 2004078178 B1 WO2004078178 B1 WO 2004078178B1 SE 2004000293 W SE2004000293 W SE 2004000293W WO 2004078178 B1 WO2004078178 B1 WO 2004078178B1
Authority
WO
WIPO (PCT)
Prior art keywords
carbon atoms
alkenyl
alkyl
hydrogen
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/SE2004/000293
Other languages
English (en)
Other versions
WO2004078178A1 (fr
Inventor
Markus Heilig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2004078178A1 publication Critical patent/WO2004078178A1/fr
Publication of WO2004078178B1 publication Critical patent/WO2004078178B1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cette invention concerne un composé de buprenorphine ou un sel ou ester pharmaceutiquement acceptable de celui-ci pour la préparation d'une composition pharmaceutique permettant de prévenir ou de traiter la dépendance à l'alcool et la consommation excessive d'alcool. Elle se rapporte aussi à l'utilisation d'un composé de buprenorphine avec un antagoniste récepteur d'opiacé, ainsi qu'à un procédé de traitement ou de prévention de la dépendance à l'alcool et de la consommation excessive d'alcool.
PCT/SE2004/000293 2003-03-03 2004-03-03 Composes de buprenorphine pour le traitement de la dependance a l'alcool et de la consommation excessive d'alcool Ceased WO2004078178A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31998803P 2003-03-03 2003-03-03
US60/319,988 2003-03-03

Publications (2)

Publication Number Publication Date
WO2004078178A1 WO2004078178A1 (fr) 2004-09-16
WO2004078178B1 true WO2004078178B1 (fr) 2005-01-27

Family

ID=32961189

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SE2004/000293 Ceased WO2004078178A1 (fr) 2003-03-03 2004-03-03 Composes de buprenorphine pour le traitement de la dependance a l'alcool et de la consommation excessive d'alcool

Country Status (1)

Country Link
WO (1) WO2004078178A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7511054B2 (en) 2006-09-22 2009-03-31 Alltranz Inc. Transdermally deliverable opioid prodrugs, abuse-resistant compositions and methods of using opioid prodrugs
GB201111775D0 (en) 2011-07-08 2011-08-24 Univ Bath Compounds and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4882335A (en) * 1988-06-13 1989-11-21 Alko Limited Method for treating alcohol-drinking response
AU765496C (en) * 1999-08-27 2005-08-25 Brookwood Pharmaceuticals Inc. Injectable buprenorphine microparticle compositions and their use

Also Published As

Publication number Publication date
WO2004078178A1 (fr) 2004-09-16

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121 Ep: the epo has been informed by wipo that ep was designated in this application
DPEN Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed from 20040101)
B Later publication of amended claims

Effective date: 20040811

122 Ep: pct application non-entry in european phase