WO2003013612A1 - Compositions contenant du polysaccharide et leur utilisation - Google Patents
Compositions contenant du polysaccharide et leur utilisation Download PDFInfo
- Publication number
- WO2003013612A1 WO2003013612A1 PCT/JP2002/008225 JP0208225W WO03013612A1 WO 2003013612 A1 WO2003013612 A1 WO 2003013612A1 JP 0208225 W JP0208225 W JP 0208225W WO 03013612 A1 WO03013612 A1 WO 03013612A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- low viscosity
- liquid
- eyedrops
- agar
- high concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0046—Ear
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
- A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
- A23L29/256—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from seaweeds, e.g. alginates, agar or carrageenan
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
- A23L29/269—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of microbial origin, e.g. xanthan or dextran
- A23L29/272—Gellan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/12—Agar or agar-agar, i.e. mixture of agarose and agaropectin; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Ophthalmology & Optometry (AREA)
- Nutrition Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Birds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Edible Seaweed (AREA)
- General Preparation And Processing Of Foods (AREA)
- Jellies, Jams, And Syrups (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2004-7001990A KR20040023740A (ko) | 2001-08-10 | 2002-08-12 | 다당류 함유 조성물 및 그의 용도 |
| US10/486,122 US20040266725A1 (en) | 2001-08-10 | 2002-08-12 | Polysaccharide-containing compositions and use thereof |
| CA002456833A CA2456833A1 (en) | 2001-08-10 | 2002-08-12 | Polysaccharide-containing compositions and use thereof |
| EP02758837A EP1424081A4 (en) | 2001-08-10 | 2002-08-12 | COMPOSITIONS CONTAINING POLYSACCHARIDE AND USE THEREOF |
| US11/810,524 US20080199524A1 (en) | 2001-08-10 | 2007-06-06 | Eyedrops containing particulate agar |
| US12/806,550 US20100317615A1 (en) | 2001-08-10 | 2010-08-16 | Method of enhancing ocular penetration of a drug in an eyedrop |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001243827 | 2001-08-10 | ||
| JP2001-243827 | 2001-08-10 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US11/810,524 Division US20080199524A1 (en) | 2001-08-10 | 2007-06-06 | Eyedrops containing particulate agar |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2003013612A1 true WO2003013612A1 (fr) | 2003-02-20 |
Family
ID=19073858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/JP2002/008225 Ceased WO2003013612A1 (fr) | 2001-08-10 | 2002-08-12 | Compositions contenant du polysaccharide et leur utilisation |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20040266725A1 (ja) |
| EP (2) | EP1424081A4 (ja) |
| JP (1) | JP2008201789A (ja) |
| KR (2) | KR100943105B1 (ja) |
| CN (2) | CN1319597C (ja) |
| CA (2) | CA2456833A1 (ja) |
| WO (1) | WO2003013612A1 (ja) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005046728A1 (ja) * | 2003-11-10 | 2005-05-26 | Toray Industries, Inc. | 多糖類含有組成物および涙液層安定化点眼剤 |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7381423B2 (en) * | 1998-05-11 | 2008-06-03 | Ciba Specialty Chemicals Corp. | Use of nanodispersions in cosmetic end formulations |
| TW592713B (en) | 1998-05-11 | 2004-06-21 | Ciba Sc Holding Ag | Use of nanodispersions in cosmetic end formulations |
| ATE439121T1 (de) * | 2004-02-26 | 2009-08-15 | Bausch & Lomb | Viskoelastische alginat-zusammensetzung, herstellungsverfahren und verpackung |
| ITRM20050443A1 (it) * | 2005-08-12 | 2007-02-13 | Opocrin Spa | Preparati oftalmici a base di polisaccaridi mucoadesivi con capacita' riepitelizzante della cornea. |
| FR2912610B1 (fr) * | 2007-02-20 | 2009-05-15 | Gervais Danone Sa | Produit alimentaire semi-fluide comprenant des fibres de beta-glucane |
| JP4642905B2 (ja) * | 2009-01-22 | 2011-03-02 | 株式会社資生堂 | 乳化化粧料 |
| DK2575971T3 (en) * | 2010-05-24 | 2016-02-29 | Indena Spa | Combined plant extracts for use in the treatment of microbial infections |
| US8530449B2 (en) | 2010-09-09 | 2013-09-10 | Assad S. Sawaya | Composition for a topical ophthalmic clear colloidal liquid which undergoes a liquid-gel phase transition in the eye |
| RU2452478C1 (ru) * | 2011-02-21 | 2012-06-10 | Общество с ограниченной ответственностью "Научно-производственная компания Уралбиофарм" | Многофункциональный раствор для эпибульбарных инстилляций |
| BR112014014147B1 (pt) * | 2011-12-15 | 2020-05-05 | Nestec Sa | produto nutricional, método para sua fabricação, e usos de uma solução aquosa de um biopolímero de grau alimentício. |
| US8865888B2 (en) | 2012-07-27 | 2014-10-21 | Shiu-Nan Chen | Composite glucan and method for preparing the same |
| JP2014152172A (ja) * | 2013-02-08 | 2014-08-25 | Daiya Seiyaku Kk | 清涼感付与外用組成物、清涼感付与貼付剤、清涼感付与方法、清涼感付与外用組成物の製造方法、及び、清涼感付与貼付剤の製造方法 |
| US10596108B2 (en) * | 2013-05-17 | 2020-03-24 | Societe Des Produits Nestle S.A. | Method for treating a swallowing disorder |
| JP6828427B2 (ja) * | 2015-12-28 | 2021-02-10 | ライオン株式会社 | 眼科用組成物及びその製造方法 |
| JP2018030893A (ja) * | 2017-11-14 | 2018-03-01 | ダイヤ製薬株式会社 | 清涼感付与外用組成物の製造方法及び清涼感付与貼付剤の製造方法 |
| GB201820018D0 (en) * | 2018-12-07 | 2019-01-23 | Univ Birmingham | Therapeutic hydrogel compositions |
| GB201820021D0 (en) * | 2018-12-07 | 2019-01-23 | Univ Birmingham | Ocular hydrogel compositions |
| CN113372573B (zh) * | 2021-06-25 | 2023-11-21 | 齐齐哈尔大学 | 一种室温下流动态琼脂糖混合溶胶的制备方法 |
| CN114504550B (zh) * | 2022-04-18 | 2022-08-19 | 中山大学中山眼科中心 | 一种包含甲硝唑的眼用凝胶及其制备方法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0267015A2 (en) * | 1986-11-05 | 1988-05-11 | Ethicon, Inc. | Stabilized compositions containing epidermal growth factor |
| EP0355908A1 (en) * | 1988-08-17 | 1990-02-28 | Unilever N.V. | Liquid based composition comprising gelling polysaccharide capable of forming a reversible gel and a method for preparing such composition |
| JPH10309182A (ja) * | 1997-03-11 | 1998-11-24 | Ina Food Ind Co Ltd | 寒天及びその製造方法 |
| JP2000041594A (ja) * | 1998-07-31 | 2000-02-15 | Ina Food Ind Co Ltd | 増粘用添加液 |
| JP2000159624A (ja) * | 1998-11-27 | 2000-06-13 | Ina Food Ind Co Ltd | 化粧料 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2909531A (en) * | 1958-01-17 | 1959-10-20 | Us Vitamin Pharm Corp | Succinate esters |
| US3867519A (en) * | 1972-04-27 | 1975-02-18 | Alza Corp | Bioerodible drug delivery device |
| US4014335A (en) * | 1975-04-21 | 1977-03-29 | Alza Corporation | Ocular drug delivery device |
| US4188373A (en) | 1976-02-26 | 1980-02-12 | Cooper Laboratories, Inc. | Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes |
| JPS6056684B2 (ja) | 1977-11-07 | 1985-12-11 | 東興薬品工業株式会社 | 点眼剤 |
| US4478822A (en) * | 1983-05-16 | 1984-10-23 | Merck & Co., Inc. | Drug delivery system utilizing thermosetting gels |
| FR2588189B1 (fr) | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| IE63392B1 (en) | 1988-02-08 | 1995-04-19 | Insite Vision Inc | Ophthalmic suspensions |
| DE68927567T2 (de) * | 1988-08-17 | 1997-04-17 | Unilever Nv | Flüssiges Gemisch, das ein zur Bildung eines reversiblen Gels befähigtes Polysaccharid-Verdickungsmittel enthält und Verfahren zu seiner Herstellung |
| GB8928370D0 (en) | 1989-12-15 | 1990-02-21 | Unilever Plc | Fluid composition |
| JP2536806B2 (ja) * | 1991-03-27 | 1996-09-25 | アルコン ラボラトリーズ インコーポレイテッド | ゲル化多糖類と微粉砕された薬剤担体とを組み合わせた局部眼科用組成物 |
| US5212162A (en) * | 1991-03-27 | 1993-05-18 | Alcon Laboratories, Inc. | Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions |
| JP2873530B2 (ja) | 1991-12-13 | 1999-03-24 | 参天製薬株式会社 | ニュートン型粘性を示すカルボキシビニルポリマー含有点眼液基剤 |
| IT1283911B1 (it) * | 1996-02-05 | 1998-05-07 | Farmigea Spa | Soluzioni oftalmiche viscosizzate con polisaccaridi della gomma di tamarindo |
| FR2746010B1 (fr) * | 1996-03-12 | 1998-04-24 | Emulsion eau-dans-huile gelifiee stable et son utilisation dans les domaines cosmetique, dermatologique, veterinaire et/ou agroalimentaire | |
| CH690814A5 (it) * | 1996-11-04 | 2001-01-31 | Applied Pharma Res | Composizioni per uso topico contenenti polisaccaridi solfati. |
| US6319507B1 (en) * | 1997-05-02 | 2001-11-20 | Kobo Products, Inc. | Agar gel bead composition and method |
| US5977209A (en) * | 1998-02-02 | 1999-11-02 | Xerox Corporation | Ink compositions |
| US6093439A (en) | 1998-05-08 | 2000-07-25 | National Starch And Chemical Investment Holding Corporation | Hydrocolloid composition for use as a gelling agent viscosifier and stabilizer |
| JP4376332B2 (ja) | 1998-10-08 | 2009-12-02 | 日本イオン株式会社 | 金属イオン及び塩素による液体の殺菌殺藻装置及び方法 |
| JP4298832B2 (ja) * | 1998-12-11 | 2009-07-22 | パイロットインキ株式会社 | ボールペン用インキ逆流防止体組成物及びそれを用いたボールペン |
| JP2000239147A (ja) * | 1999-02-18 | 2000-09-05 | Naris Cosmetics Co Ltd | 化粧料 |
| EP1683528A4 (en) * | 2003-11-10 | 2011-07-27 | Toray Industries | POLYSACCHARIDE-CONTAINING COMPOSITION AND OPHTHALMIC SOLUTION FOR STABILIZING THE TISSUE FILM |
-
2002
- 2002-08-12 KR KR1020097014799A patent/KR100943105B1/ko not_active Expired - Fee Related
- 2002-08-12 EP EP02758837A patent/EP1424081A4/en not_active Withdrawn
- 2002-08-12 CA CA002456833A patent/CA2456833A1/en not_active Abandoned
- 2002-08-12 CN CNB028176111A patent/CN1319597C/zh not_active Expired - Fee Related
- 2002-08-12 KR KR10-2004-7001990A patent/KR20040023740A/ko not_active Ceased
- 2002-08-12 CA CA2701551A patent/CA2701551A1/en not_active Abandoned
- 2002-08-12 US US10/486,122 patent/US20040266725A1/en not_active Abandoned
- 2002-08-12 EP EP10002999A patent/EP2213308A1/en not_active Withdrawn
- 2002-08-12 CN CNB2006100659029A patent/CN100467066C/zh not_active Expired - Fee Related
- 2002-08-12 WO PCT/JP2002/008225 patent/WO2003013612A1/ja not_active Ceased
-
2008
- 2008-04-03 JP JP2008097280A patent/JP2008201789A/ja not_active Withdrawn
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0267015A2 (en) * | 1986-11-05 | 1988-05-11 | Ethicon, Inc. | Stabilized compositions containing epidermal growth factor |
| EP0355908A1 (en) * | 1988-08-17 | 1990-02-28 | Unilever N.V. | Liquid based composition comprising gelling polysaccharide capable of forming a reversible gel and a method for preparing such composition |
| JPH10309182A (ja) * | 1997-03-11 | 1998-11-24 | Ina Food Ind Co Ltd | 寒天及びその製造方法 |
| JP2000041594A (ja) * | 1998-07-31 | 2000-02-15 | Ina Food Ind Co Ltd | 増粘用添加液 |
| JP2000159624A (ja) * | 1998-11-27 | 2000-06-13 | Ina Food Ind Co Ltd | 化粧料 |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005046728A1 (ja) * | 2003-11-10 | 2005-05-26 | Toray Industries, Inc. | 多糖類含有組成物および涙液層安定化点眼剤 |
| JP2010065055A (ja) * | 2003-11-10 | 2010-03-25 | Santen Pharmaceut Co Ltd | コンタクトレンズ装着または保存剤または寒天含有点眼剤 |
| CN1878571B (zh) * | 2003-11-10 | 2010-09-08 | 东丽株式会社 | 含有多糖类的组合物及泪液层稳定化滴眼剂 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1424081A4 (en) | 2005-09-21 |
| KR20040023740A (ko) | 2004-03-18 |
| KR100943105B1 (ko) | 2010-02-18 |
| CA2701551A1 (en) | 2003-02-20 |
| CN1553816A (zh) | 2004-12-08 |
| CN1319597C (zh) | 2007-06-06 |
| CN1853727A (zh) | 2006-11-01 |
| EP1424081A1 (en) | 2004-06-02 |
| JP2008201789A (ja) | 2008-09-04 |
| US20040266725A1 (en) | 2004-12-30 |
| CN100467066C (zh) | 2009-03-11 |
| CA2456833A1 (en) | 2003-02-20 |
| KR20090085161A (ko) | 2009-08-06 |
| EP2213308A1 (en) | 2010-08-04 |
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