WO2003010302A1 - Cultured cell construct containing spheroids of cultured animal cells and utilization thereof - Google Patents

Cultured cell construct containing spheroids of cultured animal cells and utilization thereof Download PDF

Info

Publication number: WO2003010302A1
Authority: WO; WIPO (PCT)
Prior art keywords: cultured; utilization; animal cells; construct containing; cell construct
Prior art date: 2001-07-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

PCT/JP2002/007539

Other languages

English (en)

French (fr)

Inventor

Kazunori Kataoka

Hidenori Otsuka

Teruo Okano

Yukio Nagasaki

Yasuhiro Horiike

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Individual

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-26

Filing date

2002-07-25

Publication date

2003-02-06

2002-07-25 Application filed by Individual filed Critical Individual

2002-07-25 Priority to CN028148428A priority Critical patent/CN1798832B/zh

2002-07-25 Priority to JP2003515653A priority patent/JP4111446B2/ja

2002-07-25 Priority to US10/484,839 priority patent/US7470424B2/en

2002-07-25 Priority to CA2454807A priority patent/CA2454807C/en

2002-07-25 Priority to DE60228594T priority patent/DE60228594D1/de

2002-07-25 Priority to EP02755656A priority patent/EP1428871B1/en

2002-07-25 Priority to KR1020047000851A priority patent/KR100675533B1/ko

2003-02-06 Publication of WO2003010302A1 publication Critical patent/WO2003010302A1/ja

2004-01-26 Anticipated expiration legal-status Critical

2008-09-08 Priority to US12/230,916 priority patent/US7691369B2/en

Status Ceased legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/067—Hepatocytes
- C12N5/0671—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/14—Coculture with; Conditioned medium produced by hepatocytes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/28—Vascular endothelial cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2535/00—Supports or coatings for cell culture characterised by topography
- C12N2535/10—Patterned coating

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Life Sciences & Earth Sciences (AREA)
Biotechnology (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biochemistry (AREA)
Microbiology (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Cell Biology (AREA)
Gastroenterology & Hepatology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)

PCT/JP2002/007539 2001-07-26 2002-07-25 Cultured cell construct containing spheroids of cultured animal cells and utilization thereof Ceased WO2003010302A1 (en)

Priority Applications (8)

Application Number	Priority Date	Filing Date	Title
CN028148428A CN1798832B (zh)	2001-07-26	2002-07-25	含有动物培养细胞球状体的培养细胞构成物及其用途
JP2003515653A JP4111446B2 (ja)	2001-07-26	2002-07-25	動物の培養細胞のスフェロイドを含む培養細胞構築物およびその使用
US10/484,839 US7470424B2 (en)	2001-07-26	2002-07-25	Cultured cell construct containing spheroids of cultured animal cells and utilization thereof
CA2454807A CA2454807C (en)	2001-07-26	2002-07-25	Cultured cell construct which contains spheroids of cultured animal cells and the use thereof
DE60228594T DE60228594D1 (de)	2001-07-26	2002-07-25	Konstrukt aus kultivierten zellen mit spheroiden von kultivierten tierzellen und verwendung davon
EP02755656A EP1428871B1 (en)	2001-07-26	2002-07-25	Cultured cell construct containing spheroids of cultured animal cells and utilization thereof
KR1020047000851A KR100675533B1 (ko)	2001-07-26	2002-07-25	동물의 배양 세포의 스페로이드를 함유한 배양 세포구축물 및 그 사용
US12/230,916 US7691369B2 (en)	2001-07-26	2008-09-08	Cultured cell construct which contains spheroids of cultured animal cells and the use thereof

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2001-226293		2001-07-26
JP2001226293		2001-07-26

Related Child Applications (2)

Application Number	Title	Priority Date	Filing Date
US10484839 A-371-Of-International		2002-07-25
US12/230,916 Division US7691369B2 (en)	2001-07-26	2008-09-08	Cultured cell construct which contains spheroids of cultured animal cells and the use thereof

Publications (1)

Publication Number	Publication Date
WO2003010302A1 true WO2003010302A1 (en)	2003-02-06

Family

ID=19059133

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PCT/JP2002/007539 Ceased WO2003010302A1 (en)	2001-07-26	2002-07-25	Cultured cell construct containing spheroids of cultured animal cells and utilization thereof

Country Status (9)

Country	Link
US (2)	US7470424B2 (ja)
EP (2)	EP1428871B1 (ja)
JP (1)	JP4111446B2 (ja)
KR (1)	KR100675533B1 (ja)
CN (1)	CN1798832B (ja)
AT (1)	ATE406436T1 (ja)
CA (1)	CA2454807C (ja)
DE (2)	DE60236974D1 (ja)
WO (1)	WO2003010302A1 (ja)

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JP2007135593A (ja) *	2005-11-18	2007-06-07	Lifescan Inc	細胞クラスターの生成法
EP1961809A1 (en)	2007-02-20	2008-08-27	FUJIFILM Corporation	Tissue construct-forming substrate, tissue construct-forming kit, method for forming tissue construct using the same and three-dimensional tissue construct formed by the method
JP2008545410A (ja) *	2005-05-24	2008-12-18	ザレジェンツオブザユニヴァースティオブカリフォルニア	微小規模のマイクロパターン化インビトロ操作・作製組織
WO2009050965A1 (ja) *	2007-10-19	2009-04-23	Japan As Represented By General Director Of Agency Of National Center For Child Health And Development	細胞凍結物固定化基材及び初代肝細胞培養ツール、並びに初代肝細胞培養ツールの製造方法
WO2009072590A1 (ja) *	2007-12-06	2009-06-11	Tokyo University Of Science Educational Foundation Administrative Organization	分岐ポリアルキレングリコール誘導体、感光性組成物、架橋体及び基板
WO2010047171A1 (ja) *	2008-10-22	2010-04-29	学校法人東京女子医科大学	細胞パターン回収ツール
JP2010233538A (ja) *	2009-03-31	2010-10-21	Trans Parent:Kk	基質代謝物の評価方法
JP2013504303A (ja) *	2009-05-05	2013-02-07	ユニヴァシティーオブペーチュ	肺組織モデル
US8592139B2 (en)	2006-11-10	2013-11-26	Dai Nippon Printing Co., Ltd.	Test method using cells and test kit therefor
US8741645B2 (en)	2006-11-10	2014-06-03	Dai Nippon Printing Co., Ltd.	Test kit comprising a culture instrument with a cell pattern and a gel suitable to embed cell pattern
US8835173B2 (en)	2006-05-29	2014-09-16	Dai Nippon Printing Co., Ltd.	Substrate for cell culture
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2002
- 2002-07-25 DE DE60236974T patent/DE60236974D1/de not_active Expired - Lifetime
- 2002-07-25 CA CA2454807A patent/CA2454807C/en not_active Expired - Fee Related
- 2002-07-25 EP EP02755656A patent/EP1428871B1/en not_active Expired - Lifetime
- 2002-07-25 US US10/484,839 patent/US7470424B2/en not_active Expired - Fee Related
- 2002-07-25 CN CN028148428A patent/CN1798832B/zh not_active Expired - Fee Related
- 2002-07-25 AT AT02755656T patent/ATE406436T1/de not_active IP Right Cessation
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Publication number	Publication date
EP1939280B1 (en)	2010-07-07
EP1939280A1 (en)	2008-07-02
EP1428871A4 (en)	2004-11-24
JP4111446B2 (ja)	2008-07-02
JPWO2003010302A1 (ja)	2005-06-02
US20040197907A1 (en)	2004-10-07
CN1798832B (zh)	2010-04-28
DE60228594D1 (de)	2008-10-09
KR100675533B1 (ko)	2007-01-29
CA2454807C (en)	2012-09-18
US20090011504A1 (en)	2009-01-08
KR20040025700A (ko)	2004-03-24
CN1798832A (zh)	2006-07-05
CA2454807A1 (en)	2003-02-06
EP1428871B1 (en)	2008-08-27
US7691369B2 (en)	2010-04-06
ATE406436T1 (de)	2008-09-15
DE60236974D1 (de)	2010-08-19
EP1428871A1 (en)	2004-06-16
US7470424B2 (en)	2008-12-30

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