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WO2002016941A3 - Methode combinatoire de criblage rapide de preparations d'administration de medicaments - Google Patents

Methode combinatoire de criblage rapide de preparations d'administration de medicaments Download PDF

Info

Publication number
WO2002016941A3
WO2002016941A3 PCT/US2001/026473 US0126473W WO0216941A3 WO 2002016941 A3 WO2002016941 A3 WO 2002016941A3 US 0126473 W US0126473 W US 0126473W WO 0216941 A3 WO0216941 A3 WO 0216941A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug delivery
rapid screening
formulations
substance
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/026473
Other languages
English (en)
Other versions
WO2002016941A2 (fr
Inventor
Samir Mitragotri
Pankaj Karande
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California Berkeley
University of California San Diego UCSD
Original Assignee
University of California Berkeley
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California Berkeley, University of California San Diego UCSD filed Critical University of California Berkeley
Priority to US10/344,961 priority Critical patent/US20040023841A1/en
Priority to AU2001286725A priority patent/AU2001286725A1/en
Publication of WO2002016941A2 publication Critical patent/WO2002016941A2/fr
Publication of WO2002016941A3 publication Critical patent/WO2002016941A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne une nouvelle méthode de criblage rapide de préparations d'administration de médicaments, ladite méthode faisant appel à un jeu ordonné d'échantillons à rendement élevé pour cribler plusieurs échantillons. Cette méthode surveille la déplétion d'une substance d'essai à partir d'une cupule donatrice, la migration de la substance dans une membrane d'essai, et/ou la migration de la substance à travers une membrane dans une cupule réceptrice. On peut l'utiliser pour découvrir de nouvelles préparations, ainsi que pour optimiser les préparations existantes d'administration de médicaments par voies transdermiques, orales ou injectables.
PCT/US2001/026473 2000-08-23 2001-08-23 Methode combinatoire de criblage rapide de preparations d'administration de medicaments Ceased WO2002016941A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US10/344,961 US20040023841A1 (en) 2001-08-23 2001-08-23 Combinatorial method for rapid screening of drug delivery formulations
AU2001286725A AU2001286725A1 (en) 2000-08-23 2001-08-23 A combinatorial method for rapid screening of drug delivery formulations

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22745300P 2000-08-23 2000-08-23
US60/227,453 2000-08-23

Publications (2)

Publication Number Publication Date
WO2002016941A2 WO2002016941A2 (fr) 2002-02-28
WO2002016941A3 true WO2002016941A3 (fr) 2003-01-03

Family

ID=22853172

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/026473 Ceased WO2002016941A2 (fr) 2000-08-23 2001-08-23 Methode combinatoire de criblage rapide de preparations d'administration de medicaments

Country Status (2)

Country Link
AU (1) AU2001286725A1 (fr)
WO (1) WO2002016941A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7788701A (en) 2000-07-14 2002-01-30 Transform Pharmaceuticals Inc System and method for optimizing tissue barrier transfer of compounds
US6852526B2 (en) 2000-07-14 2005-02-08 Transform Pharmaceuticals, Inc. Transdermal assay with magnetic clamp
US7172859B2 (en) 2000-07-14 2007-02-06 Transform Pharmaceuticals, Inc. System and method for optimizing tissue barrier transfer of compounds
US7449307B2 (en) 2002-10-28 2008-11-11 Transform Pharmaceuticals, Inc. Raised surface assay plate
EP1556501A4 (fr) * 2002-10-28 2009-04-08 Transform Pharmaceuticals Inc Dosage transdermique a l'aide d'un dispositif de blocage magnetique
CA2530407A1 (fr) * 2003-07-23 2005-02-03 The Regents Of The University Of California Combinaisons d'amplificateurs de penetration pour administration transdermique
US20050065062A1 (en) * 2003-09-24 2005-03-24 3M Innovative Properties Company Method of formulating a pharmaceutical composition
US7635452B2 (en) * 2003-09-24 2009-12-22 3M Innovative Properties Company System, kit, and method for measuring membrane diffusion
CN103323496B (zh) * 2013-05-24 2018-12-18 中国人民解放军第二五一医院 高通量经皮腐蚀与吸收检测板
CN103308564A (zh) * 2013-06-03 2013-09-18 拉芳家化股份有限公司 一种化妆品活性成分经皮吸收效率的检测方法
CN113514370B (zh) * 2021-04-14 2024-09-27 广州呼吸药物工程技术有限公司 一种用于测定载药非血管支架药物的单向渗透性装置及测定方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260210A (en) * 1989-09-27 1993-11-09 Rubin Lee L Blood-brain barrier model
US5814599A (en) * 1995-08-04 1998-09-29 Massachusetts Insitiute Of Technology Transdermal delivery of encapsulated drugs

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260210A (en) * 1989-09-27 1993-11-09 Rubin Lee L Blood-brain barrier model
US5814599A (en) * 1995-08-04 1998-09-29 Massachusetts Insitiute Of Technology Transdermal delivery of encapsulated drugs

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TANG HUA ET AL: "Theoretical description of transdermal transport of hydrophilic permeants: Application to low-frequency sonophoresis.", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 90, no. 5, May 2001 (2001-05-01), pages 545 - 568, XP001096081, ISSN: 0022-3549 *

Also Published As

Publication number Publication date
AU2001286725A1 (en) 2002-03-04
WO2002016941A2 (fr) 2002-02-28

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