WO2002048146A3 - Verwendung von substituierten imidazoazinen, neue imidazoazine, verfahren zu deren herstellung, sowie sie enthaltende mittel - Google Patents
Verwendung von substituierten imidazoazinen, neue imidazoazine, verfahren zu deren herstellung, sowie sie enthaltende mittel Download PDFInfo
- Publication number
- WO2002048146A3 WO2002048146A3 PCT/EP2001/014577 EP0114577W WO0248146A3 WO 2002048146 A3 WO2002048146 A3 WO 2002048146A3 EP 0114577 W EP0114577 W EP 0114577W WO 0248146 A3 WO0248146 A3 WO 0248146A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- atoms
- membered
- atom
- imidazoazines
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2002224927A AU2002224927A1 (en) | 2000-12-13 | 2001-12-12 | Use of substituted imidazoazines, novel imidazoazines, methods for the production thereof, and agents containing these compounds |
| US10/433,440 US20040058938A1 (en) | 2000-12-13 | 2001-12-12 | Use of substituted imidazoazines, novel imidazoazines, methods for the production thereof, and agents containing these compounds |
| EP01994779A EP1343785A2 (de) | 2000-12-13 | 2001-12-12 | Verwendung von substituierten imidazoazinen, neue imidazoazine, verfahren zu deren herstellung, sowie sie enthaltende mittel |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10061983 | 2000-12-13 | ||
| DE10061983.5 | 2000-12-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2002048146A2 WO2002048146A2 (de) | 2002-06-20 |
| WO2002048146A3 true WO2002048146A3 (de) | 2002-11-14 |
Family
ID=7666908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EP2001/014577 Ceased WO2002048146A2 (de) | 2000-12-13 | 2001-12-12 | Verwendung von substituierten imidazoazinen, neue imidazoazine, verfahren zu deren herstellung, sowie sie enthaltende mittel |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20040058938A1 (de) |
| EP (1) | EP1343785A2 (de) |
| AU (1) | AU2002224927A1 (de) |
| WO (1) | WO2002048146A2 (de) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2007014510A (es) * | 2005-05-20 | 2008-02-05 | Array Biopharma Inc | Compuestos inhibidores de raf y metodos de uso de los mismos. |
| CA2730280A1 (en) * | 2008-07-10 | 2010-01-14 | Southern Research Institute | 5-quinolinone and imidazopyridine compounds and use thereof |
| CN102216298B (zh) * | 2008-09-16 | 2014-04-16 | Csir公司 | 作为hiv-1逆转录酶抑制剂的咪唑并吡啶和咪唑并嘧啶 |
| US20120220581A1 (en) | 2009-10-30 | 2012-08-30 | Janssen-Cilag, S.A. | IMIDAZO[1,2-b]PYRIDAZINE DERIVATIVES AND THEIR USE AS PDE10 INHIBITORS |
| AR080754A1 (es) | 2010-03-09 | 2012-05-09 | Janssen Pharmaceutica Nv | Derivados de imidazo (1,2-a) pirazina y su uso como inhibidores de pde10 |
| EP2723744B1 (de) | 2011-06-27 | 2016-03-23 | Janssen Pharmaceutica, N.V. | 1-aryl-4-methyl-[1,2,4]triazolo[4,3-a]-chinoxalin-derivate |
| RU2657540C2 (ru) | 2012-06-26 | 2018-06-14 | Янссен Фармацевтика Нв | Комбинации, содержащие ингибиторы pde 2, такие как 1-арил-4-метил-[1,2,4]триазоло[4,3-а]хиноксалиновые соединения, и ингибиторы pde 10, для применения в лечении неврологических или метаболических расстройств |
| ES2607184T3 (es) | 2012-07-09 | 2017-03-29 | Janssen Pharmaceutica, N.V. | Inhibidores de la enzima fosfodiesterasa 10 |
| RU2015118985A (ru) * | 2012-11-14 | 2017-01-10 | Ф. Хоффманн-Ля Рош Аг | Производные имидазопиридина |
| PH12020552066A1 (en) | 2014-02-13 | 2022-05-11 | Incyte Corp | Cyclopropylamines as lsd1 inhibitors |
| US9527835B2 (en) | 2014-02-13 | 2016-12-27 | Incyte Corporation | Cyclopropylamines as LSD1 inhibitors |
| RS59534B1 (sr) | 2014-02-13 | 2019-12-31 | Incyte Corp | Ciklopropilamini kao lsd1 inhibitori |
| ES2672797T3 (es) | 2014-02-13 | 2018-06-18 | Incyte Corporation | Ciclopropilaminas como inhibidores de LSD1 |
| US9758523B2 (en) | 2014-07-10 | 2017-09-12 | Incyte Corporation | Triazolopyridines and triazolopyrazines as LSD1 inhibitors |
| TWI687419B (zh) | 2014-07-10 | 2020-03-11 | 美商英塞特公司 | 作為lsd1抑制劑之咪唑并吡啶及咪唑并吡嗪 |
| WO2016007736A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Imidazopyrazines as lsd1 inhibitors |
| WO2016007722A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Triazolopyridines and triazolopyrazines as lsd1 inhibitors |
| EP3626720A1 (de) | 2015-04-03 | 2020-03-25 | Incyte Corporation | Heterocyclische verbindungen als lsd1-hemmer |
| MX389824B (es) | 2015-08-12 | 2025-03-20 | Incyte Holdings Corp | Sales de un inhibidor de dimetilasa 1 especifica para lisina (lsd1). |
| TW201718581A (zh) | 2015-10-19 | 2017-06-01 | 英塞特公司 | 作為免疫調節劑之雜環化合物 |
| LT3377488T (lt) | 2015-11-19 | 2023-01-10 | Incyte Corporation | Heterocikliniai junginiai, kaip imunomoduliatoriai |
| US20170174679A1 (en) | 2015-12-22 | 2017-06-22 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| IL262488B (en) | 2016-04-22 | 2022-08-01 | Incyte Corp | lsdi inhibitor formulations |
| MA44860A (fr) | 2016-05-06 | 2019-03-13 | Incyte Holdings Corp | Composés hétérocycliques utilisés comme immunomodulateurs |
| WO2017205464A1 (en) | 2016-05-26 | 2017-11-30 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| HUE060256T2 (hu) | 2016-06-20 | 2023-02-28 | Incyte Corp | Heterociklusos vegyületek mint immunmodulátorok |
| US20180016260A1 (en) | 2016-07-14 | 2018-01-18 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| ES2941716T3 (es) | 2016-08-29 | 2023-05-25 | Incyte Corp | Compuestos heterocíclicos como inmunomoduladores |
| JP7303108B2 (ja) | 2016-12-22 | 2023-07-04 | インサイト・コーポレイション | 免疫調節剤としての二環式複素芳香環化合物 |
| CN116115764A (zh) | 2016-12-22 | 2023-05-16 | 因赛特公司 | 四氢咪唑并[4,5-c]吡啶衍生物作为pd-l1内在化诱导剂 |
| EP3558989B1 (de) | 2016-12-22 | 2021-04-14 | Incyte Corporation | Triazolo[1,5-a]pyridin-derivate als immunmodulatoren |
| WO2018119266A1 (en) | 2016-12-22 | 2018-06-28 | Incyte Corporation | Benzooxazole derivatives as immunomodulators |
| WO2018119221A1 (en) | 2016-12-22 | 2018-06-28 | Incyte Corporation | Pyridine derivatives as immunomodulators |
| AU2018346331B2 (en) * | 2017-10-04 | 2023-08-24 | Dana-Farber Cancer Institute, Inc. | Small molecule inhibition of transcription factor SALL4 and uses thereof |
| ES3030010T3 (en) | 2018-03-30 | 2025-06-26 | Incyte Corp | Heterocyclic compounds as immunomodulators |
| BR112020022936A2 (pt) | 2018-05-11 | 2021-02-02 | Incyte Corporation | derivados de tetra-hidro-imidazo[4,5-c]piridina como imunomoduladores de pd-l1 |
| CN108794471B (zh) * | 2018-08-27 | 2020-04-28 | 青岛农业大学 | 苯并咪唑类化合物的合成方法及其农用生物活性 |
| US10968200B2 (en) | 2018-08-31 | 2021-04-06 | Incyte Corporation | Salts of an LSD1 inhibitor and processes for preparing the same |
| CA3150434A1 (en) | 2019-08-09 | 2021-02-18 | Incyte Corporation | Salts of a pd-1/pd-l1 inhibitor |
| IL291471B2 (en) | 2019-09-30 | 2025-04-01 | Incyte Corp | Pyrimido[3,2–D]pyrimidine compounds as immunomodulators |
| JP2023500395A (ja) | 2019-11-11 | 2023-01-05 | インサイト・コーポレイション | Pd-1/pd-l1阻害剤の塩及び結晶形態 |
| US11760756B2 (en) | 2020-11-06 | 2023-09-19 | Incyte Corporation | Crystalline form of a PD-1/PD-L1 inhibitor |
| US11780836B2 (en) | 2020-11-06 | 2023-10-10 | Incyte Corporation | Process of preparing a PD-1/PD-L1 inhibitor |
| TW202233616A (zh) | 2020-11-06 | 2022-09-01 | 美商英塞特公司 | 用於製備pd-1/pd-l1抑制劑以及其鹽及結晶形式之方法 |
| AR132352A1 (es) * | 2023-04-13 | 2025-06-18 | Syngenta Crop Protection Ag | Derivados de imidazo[1,2-a]pirazina |
| AR132351A1 (es) * | 2023-04-13 | 2025-06-18 | Syngenta Crop Protection Ag | Derivados de imidazo[1,2-a]pirazina |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0215382A1 (de) * | 1985-09-17 | 1987-03-25 | BASF Aktiengesellschaft | 7-Amino-azolo[1,5-a]pyrimidine und diese enthaltende Fungizide |
| WO2001027109A2 (de) * | 1999-10-08 | 2001-04-19 | Grünenthal GmbH | Tert.-butyl-(7-methyl-imidazo[1,2-a]pyridin-3-yl)-amin-derivate |
| WO2001027111A2 (de) * | 1999-10-08 | 2001-04-19 | Grünenthal GmbH | Bicyclische imidazo-3-yl-aminderivate |
| WO2001027110A2 (de) * | 1999-10-08 | 2001-04-19 | Grünenthal GmbH | Am sechsring substituierte, bicyclische imidazo-3-yl-aminderivate |
| WO2002006286A2 (en) * | 2000-07-14 | 2002-01-24 | Bristol-Myers Squibb Pharma Company | IMIDAZO[1,2-a]PYRAZINES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS |
-
2001
- 2001-12-12 WO PCT/EP2001/014577 patent/WO2002048146A2/de not_active Ceased
- 2001-12-12 EP EP01994779A patent/EP1343785A2/de not_active Withdrawn
- 2001-12-12 US US10/433,440 patent/US20040058938A1/en not_active Abandoned
- 2001-12-12 AU AU2002224927A patent/AU2002224927A1/en not_active Abandoned
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0215382A1 (de) * | 1985-09-17 | 1987-03-25 | BASF Aktiengesellschaft | 7-Amino-azolo[1,5-a]pyrimidine und diese enthaltende Fungizide |
| WO2001027109A2 (de) * | 1999-10-08 | 2001-04-19 | Grünenthal GmbH | Tert.-butyl-(7-methyl-imidazo[1,2-a]pyridin-3-yl)-amin-derivate |
| WO2001027119A2 (de) * | 1999-10-08 | 2001-04-19 | Grünenthal GmbH | Substanzbibliothek enthaltend bicyclische imidazo-5-yl-amine und/oder bicyclische imidazo-3-yl-amine |
| WO2001027111A2 (de) * | 1999-10-08 | 2001-04-19 | Grünenthal GmbH | Bicyclische imidazo-3-yl-aminderivate |
| WO2001027110A2 (de) * | 1999-10-08 | 2001-04-19 | Grünenthal GmbH | Am sechsring substituierte, bicyclische imidazo-3-yl-aminderivate |
| WO2002006286A2 (en) * | 2000-07-14 | 2002-01-24 | Bristol-Myers Squibb Pharma Company | IMIDAZO[1,2-a]PYRAZINES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS |
Non-Patent Citations (7)
Also Published As
| Publication number | Publication date |
|---|---|
| EP1343785A2 (de) | 2003-09-17 |
| US20040058938A1 (en) | 2004-03-25 |
| AU2002224927A1 (en) | 2002-06-24 |
| WO2002048146A2 (de) | 2002-06-20 |
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