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WO2000044358A3 - Verwendung von phosphororganischen verbindungen zur prophylaktischen und therapeutischen behandlung von infektionen - Google Patents

Verwendung von phosphororganischen verbindungen zur prophylaktischen und therapeutischen behandlung von infektionen Download PDF

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Publication number
WO2000044358A3
WO2000044358A3 PCT/EP2000/000542 EP0000542W WO0044358A3 WO 2000044358 A3 WO2000044358 A3 WO 2000044358A3 EP 0000542 W EP0000542 W EP 0000542W WO 0044358 A3 WO0044358 A3 WO 0044358A3
Authority
WO
WIPO (PCT)
Prior art keywords
infections
prophylactic
compounds
therapeutical treatment
phosphororganic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2000/000542
Other languages
English (en)
French (fr)
Other versions
WO2000044358A2 (de
Inventor
Hassan Jomaa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2000595662A priority Critical patent/JP2002535354A/ja
Priority to AU24399/00A priority patent/AU2439900A/en
Priority to CA002360661A priority patent/CA2360661A1/en
Priority to SK1055-2001A priority patent/SK10552001A3/sk
Priority to EP00902630A priority patent/EP1146880A2/de
Priority to IL14411500A priority patent/IL144115A0/xx
Application filed by Individual filed Critical Individual
Priority to PL00349910A priority patent/PL349910A1/xx
Publication of WO2000044358A2 publication Critical patent/WO2000044358A2/de
Publication of WO2000044358A3 publication Critical patent/WO2000044358A3/de
Priority to NO20013651A priority patent/NO20013651L/no
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pulmonology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Verwendung von phosphororganischen Verbindungen der allgemeinen Formel (I), in der X ein Phosphoratom oder ein Schwefelatom ist, und A eine substituierte oder unsubstituierte C2-5-Alkylkette ist, zur therapeutischen und prophylaktischen Behandlung von Infektionen bei Mensch und Tier, verursacht durch Viren, Bakterien, Pilze und Parasiten und als Fungizid, Bakterizid und Herbizid bei Pflanzen.
PCT/EP2000/000542 1999-01-26 2000-01-25 Verwendung von phosphororganischen verbindungen zur prophylaktischen und therapeutischen behandlung von infektionen Ceased WO2000044358A2 (de)

Priority Applications (8)

Application Number Priority Date Filing Date Title
AU24399/00A AU2439900A (en) 1999-01-26 2000-01-25 Use of phosphororganic compounds for the prophylactic and therapeutical treatment of infections
CA002360661A CA2360661A1 (en) 1999-01-26 2000-01-25 Use of phosphororganic compounds for the prophylactic and therapeutical treatment of infections
SK1055-2001A SK10552001A3 (sk) 1999-01-26 2000-01-25 Použitie fosfororganických zlúčenín na profylaktické a terapeutické ošetrovania infekcií
EP00902630A EP1146880A2 (de) 1999-01-26 2000-01-25 Verwendung von phosphororganischen verbindungen zur prophylaktischen und therapeutischen behandlung von infektionen
IL14411500A IL144115A0 (en) 1999-01-26 2000-01-25 Use of phosphororganic compounds for the prophylactic and therapeutical treatment of infections
JP2000595662A JP2002535354A (ja) 1999-01-26 2000-01-25 感染症の予防および治療処置のための有機リン化合物の使用
PL00349910A PL349910A1 (en) 1999-01-26 2000-01-25 Use of phosphororganic compounds for the prophylactic and therapeutical treatment of infections
NO20013651A NO20013651L (no) 1999-01-26 2001-07-25 Anvendelse av fosfororganiske forbindelser for profylaktisk og terapeutisk behandling av infeksjoner

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19902924.5 1999-01-26
DE19902924A DE19902924A1 (de) 1999-01-26 1999-01-26 Verwendung von phosphororganischen Verbindungen zur prophylaktischen und therapeutischen Behandlung von Infektionen

Publications (2)

Publication Number Publication Date
WO2000044358A2 WO2000044358A2 (de) 2000-08-03
WO2000044358A3 true WO2000044358A3 (de) 2001-03-15

Family

ID=7895365

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/000542 Ceased WO2000044358A2 (de) 1999-01-26 2000-01-25 Verwendung von phosphororganischen verbindungen zur prophylaktischen und therapeutischen behandlung von infektionen

Country Status (14)

Country Link
EP (1) EP1146880A2 (de)
JP (1) JP2002535354A (de)
CN (1) CN1337881A (de)
AU (1) AU2439900A (de)
CA (1) CA2360661A1 (de)
CZ (1) CZ20012584A3 (de)
DE (1) DE19902924A1 (de)
HU (1) HUP0105310A3 (de)
IL (1) IL144115A0 (de)
NO (1) NO20013651L (de)
PL (1) PL349910A1 (de)
SK (1) SK10552001A3 (de)
TR (1) TR200102151T2 (de)
WO (1) WO2000044358A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7842719B2 (en) 2002-10-31 2010-11-30 Kemin Foods, L.C. Use of endoperoxides for the treatment of infections caused by flaviviridae, including hepatitis C, bovine viral diarrhea and classical swine fever virus
WO2004085448A2 (en) * 2003-03-19 2004-10-07 Genzyme Corporation Unsaturated phosphinyl-phosphonate phosphate transport inhibitors
US20100240612A1 (en) * 2009-03-20 2010-09-23 University Of Iowa Research Foundation Prenylated Bisphosphonates as Anti-tuberculosis Agents
CN104026151A (zh) * 2014-06-19 2014-09-10 南京麦思德餐饮管理有限公司 一种紫花苜蓿浸种剂
SG11201701928RA (en) 2014-09-12 2017-04-27 Antibiotx Aps Antibacterial use of halogenated salicylanilides
GB201509326D0 (en) 2015-05-29 2015-07-15 Antibio Tx Aps Novel use
CN105403221B (zh) * 2015-10-27 2018-01-23 广东欧珀移动通信有限公司 一种导航路线的生成方法及移动终端
US11419834B2 (en) 2019-02-25 2022-08-23 Rhode Island Hospital Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3372209A (en) * 1964-08-24 1968-03-05 Monsanto Co Diphosphorus ester hydrocarbon diols
GB1164835A (en) * 1965-10-06 1969-09-24 Monsanto Co Diphosphinite Esters, their Production and Conversion to Diphosphine Oxides
US3532774A (en) * 1966-09-29 1970-10-06 Monsanto Co Phosphinites,phosphine oxides and process for preparing
US4254114A (en) * 1979-01-02 1981-03-03 The Proctor & Gamble Company Control of pyrophosphate microorganisms with organophosphonates
EP0088359A2 (de) * 1982-03-10 1983-09-14 Henkel Kommanditgesellschaft auf Aktien Amidinodiphosphonsäuren
US4696920A (en) * 1984-07-18 1987-09-29 Symphar S.A. Certain 2-substituted 1,3-propylidenediphosphonate derivatives, pharmaceutical compositions containing them and their use as antihypertensive agents
US4820698A (en) * 1985-11-04 1989-04-11 The Procter & Gamble Company Antimicrobial agents and process for their manufacture
US5196409A (en) * 1989-08-20 1993-03-23 Yissum, Research Development Company Of The Hebrew University Of Jerusalem Bisphosphonates, pharmaceutical compositions, and process for the treatment of irregularities in calcium metabolism
DE4336099A1 (de) * 1993-10-22 1995-04-27 Boehringer Mannheim Gmbh Neue 2.4-Diphosphonoglutarsäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
WO1996016629A2 (en) * 1994-11-18 1996-06-06 Amira Inc Phosphinic creatine compounds having antiviral activity
DE19532235A1 (de) * 1995-08-31 1997-03-06 Keppler Bernhard K Priv Doz Dr An Phosphonsäuren gekoppelte antibakteriell wirksame Verbindungen zur Therapie von Infektionen im Bereich des Knochens
WO1998015560A1 (en) * 1996-10-09 1998-04-16 Elizanor Biopharmaceuticals, Inc. Diphosphonate therapeutic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3170944A (en) * 1962-11-20 1965-02-23 Stauffer Chemical Co Haloacetonyl phosphonates and a method of preparing them
JPS4861259A (de) * 1971-12-02 1973-08-28
JPS5655394A (en) * 1979-10-12 1981-05-15 Otsuka Chem Co Ltd 1,2-di alkoxycarbonylmethylamino ethylene-1,2-disulfonic acid phenyl ester derivative, its preparation, and herbicide containing said compound
GB9613637D0 (en) * 1996-06-28 1996-08-28 Agrevo Uk Ltd Fungicidal compositions

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3372209A (en) * 1964-08-24 1968-03-05 Monsanto Co Diphosphorus ester hydrocarbon diols
GB1164835A (en) * 1965-10-06 1969-09-24 Monsanto Co Diphosphinite Esters, their Production and Conversion to Diphosphine Oxides
US3532774A (en) * 1966-09-29 1970-10-06 Monsanto Co Phosphinites,phosphine oxides and process for preparing
US4254114A (en) * 1979-01-02 1981-03-03 The Proctor & Gamble Company Control of pyrophosphate microorganisms with organophosphonates
EP0088359A2 (de) * 1982-03-10 1983-09-14 Henkel Kommanditgesellschaft auf Aktien Amidinodiphosphonsäuren
US4696920A (en) * 1984-07-18 1987-09-29 Symphar S.A. Certain 2-substituted 1,3-propylidenediphosphonate derivatives, pharmaceutical compositions containing them and their use as antihypertensive agents
US4820698A (en) * 1985-11-04 1989-04-11 The Procter & Gamble Company Antimicrobial agents and process for their manufacture
US5196409A (en) * 1989-08-20 1993-03-23 Yissum, Research Development Company Of The Hebrew University Of Jerusalem Bisphosphonates, pharmaceutical compositions, and process for the treatment of irregularities in calcium metabolism
DE4336099A1 (de) * 1993-10-22 1995-04-27 Boehringer Mannheim Gmbh Neue 2.4-Diphosphonoglutarsäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
WO1996016629A2 (en) * 1994-11-18 1996-06-06 Amira Inc Phosphinic creatine compounds having antiviral activity
DE19532235A1 (de) * 1995-08-31 1997-03-06 Keppler Bernhard K Priv Doz Dr An Phosphonsäuren gekoppelte antibakteriell wirksame Verbindungen zur Therapie von Infektionen im Bereich des Knochens
WO1998015560A1 (en) * 1996-10-09 1998-04-16 Elizanor Biopharmaceuticals, Inc. Diphosphonate therapeutic compounds

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SONG, YONGHONG ET AL.: "Stereospecific Synthesis of Phosphonate Analogs of Diaminopimelic Acid (DAP), Their Interaction with DAP Enzymes, and Antibacterial Activity of Peptide Derivatives", J. ORG. CHEM., vol. 59, no. 19, 1994, pages 5784 - 5793, XP002151231 *
VAN ASSCHE ET AL: "Synthesis and antibacterial evaluation of phosphonic analogues of diaminopimelic acid", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.CHIMICA THERAPEUTICA,EDITIONS SCIENTIFIQUE ELSEVIER, PARIS,FR, vol. 26, 1991, pages 505 - 515, XP002113546, ISSN: 0223-5234 *

Also Published As

Publication number Publication date
TR200102151T2 (tr) 2002-05-21
NO20013651L (no) 2001-09-18
CN1337881A (zh) 2002-02-27
DE19902924A1 (de) 2000-08-03
CA2360661A1 (en) 2000-08-03
WO2000044358A2 (de) 2000-08-03
EP1146880A2 (de) 2001-10-24
IL144115A0 (en) 2002-05-23
JP2002535354A (ja) 2002-10-22
CZ20012584A3 (cs) 2002-01-16
NO20013651D0 (no) 2001-07-25
HUP0105310A2 (en) 2002-06-29
SK10552001A3 (sk) 2001-12-03
PL349910A1 (en) 2002-10-07
HUP0105310A3 (en) 2002-08-28
AU2439900A (en) 2000-08-18

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