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WO1999004228A3 - Dispositif de detection de lumiere - Google Patents

Dispositif de detection de lumiere Download PDF

Info

Publication number
WO1999004228A3
WO1999004228A3 PCT/US1998/014575 US9814575W WO9904228A3 WO 1999004228 A3 WO1999004228 A3 WO 1999004228A3 US 9814575 W US9814575 W US 9814575W WO 9904228 A3 WO9904228 A3 WO 9904228A3
Authority
WO
WIPO (PCT)
Prior art keywords
light detection
detection device
switch mechanisms
permit
detectors
Prior art date
Application number
PCT/US1998/014575
Other languages
English (en)
Other versions
WO1999004228A2 (fr
WO1999004228A9 (fr
Inventor
William G Burton
Kimberly L Crawford
Sudhir S Deshpande
Glenn R Edwards
Amer El-Hage
Todd E French
Vladimir Lemberg
Joseph S Leytes
Samuel A Marquiss
John W Meadows
Irina Mineyev
Douglas N Modlin
John C Owicki
Jon F Peterson
Derrick A Richardson
Rick V Stellmacher
Michael T Taylor
Original Assignee
Ljl Biosystems Inc
William G Burton
Kimberly L Crawford
Sudhir S Deshpande
Glenn R Edwards
El Hage Amer
Todd E French
Vladimir Lemberg
Joseph S Leytes
Samuel A Marquiss
John W Meadows
Irina Mineyev
Douglas N Modlin
John C Owicki
Jon F Peterson
Derrick A Richardson
Rick V Stellmacher
Michael T Taylor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ljl Biosystems Inc, William G Burton, Kimberly L Crawford, Sudhir S Deshpande, Glenn R Edwards, El Hage Amer, Todd E French, Vladimir Lemberg, Joseph S Leytes, Samuel A Marquiss, John W Meadows, Irina Mineyev, Douglas N Modlin, John C Owicki, Jon F Peterson, Derrick A Richardson, Rick V Stellmacher, Michael T Taylor filed Critical Ljl Biosystems Inc
Priority to EP98935657A priority Critical patent/EP1012579A2/fr
Priority to IL13406998A priority patent/IL134069A0/xx
Priority to JP2000503394A priority patent/JP2002509235A/ja
Priority to AU84853/98A priority patent/AU8485398A/en
Priority to US09/118,310 priority patent/US6033100A/en
Priority to US09/144,575 priority patent/US6159425A/en
Priority to US09/144,578 priority patent/US6499366B1/en
Priority to US09/146,081 priority patent/US6187267B1/en
Priority to US09/160,533 priority patent/US6097025A/en
Publication of WO1999004228A2 publication Critical patent/WO1999004228A2/fr
Publication of WO1999004228A3 publication Critical patent/WO1999004228A3/fr
Publication of WO1999004228A9 publication Critical patent/WO1999004228A9/fr
Priority to AU49990/99A priority patent/AU4999099A/en
Priority to PCT/US1999/016057 priority patent/WO2000004364A2/fr
Priority to US09/629,599 priority patent/US6469311B1/en
Priority to US09/733,370 priority patent/US20010007640A1/en
Priority to US10/445,292 priority patent/US6992761B2/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/523—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for multisample carriers, e.g. used for microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315—Microtiter plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315—Microtiter plates
    • B01J2219/00317—Microwell devices, i.e. having large numbers of wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/0061—The surface being organic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B01J2219/00691—Automatic using robots
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00702—Processes involving means for analysing and characterising the products
    • B01J2219/00707—Processes involving means for analysing and characterising the products separated from the reactor apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/809—Multifield plates or multicontainer arrays
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
    • Y10T436/114165—Automated chemical analysis with conveyance of sample along a test line in a container or rack with step of insertion or removal from test line
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/115831—Condition or time responsive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Plasma & Fusion (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Optical Couplings Of Light Guides (AREA)

Abstract

L'invention concerne un instrument et un procédé de détection de lumière à haute capacité. Dans certains modes de réalisation, des mécanismes de commutation et des systèmes de relais optiques permettent de sélectionner différentes sources de lumières et/ou photodétecteurs en vue d'applications différentes. Dans d'autres modes de réalisation, des mécanismes de commutation et des trajectoires optiques permettent d'éclairer le sommet/fond et ou de détecter le sommet/fond, ou les deux.
PCT/US1998/014575 1997-07-16 1998-07-15 Dispositif de detection de lumiere WO1999004228A2 (fr)

Priority Applications (14)

Application Number Priority Date Filing Date Title
EP98935657A EP1012579A2 (fr) 1997-07-16 1998-07-15 Dispositif de detection de lumiere
IL13406998A IL134069A0 (en) 1997-07-16 1998-07-15 Light detection device
JP2000503394A JP2002509235A (ja) 1997-07-16 1998-07-15 光検出装置
AU84853/98A AU8485398A (en) 1997-07-16 1998-07-15 Light detection device
US09/118,310 US6033100A (en) 1997-07-16 1998-07-16 Floating head assembly
US09/144,575 US6159425A (en) 1997-07-16 1998-08-31 Sample transporter
US09/144,578 US6499366B1 (en) 1997-07-16 1998-08-31 Sample feeder
US09/146,081 US6187267B1 (en) 1997-07-16 1998-09-02 Chemiluminescence detection device
US09/160,533 US6097025A (en) 1997-10-31 1998-09-24 Light detection device having an optical-path switching mechanism
AU49990/99A AU4999099A (en) 1998-07-15 1999-07-15 Evanescent field illumination devices and methods
PCT/US1999/016057 WO2000004364A2 (fr) 1998-07-15 1999-07-15 Dispositifs et procedes d'illumination de champ evanescent
US09/629,599 US6469311B1 (en) 1997-07-16 2000-07-31 Detection device for light transmitted from a sensed volume
US09/733,370 US20010007640A1 (en) 1997-07-16 2000-12-08 Sample transporter
US10/445,292 US6992761B2 (en) 1997-09-20 2003-05-22 Broad range light detection system

Applications Claiming Priority (26)

Application Number Priority Date Filing Date Title
US5287697P 1997-07-16 1997-07-16
US60/052,876 1997-07-16
US5963997P 1997-09-20 1997-09-20
US60/059,639 1997-09-20
US6381197P 1997-10-31 1997-10-31
US60/063,811 1997-10-31
US7249998P 1998-01-26 1998-01-26
US60/072,499 1998-01-26
US7278098P 1998-01-27 1998-01-27
US60/072,780 1998-01-27
US7541498P 1998-02-20 1998-02-20
US60/075,414 1998-02-20
US7580698P 1998-02-24 1998-02-24
US60/075,806 1998-02-24
US8225398P 1998-04-17 1998-04-17
US09/062,472 US6071748A (en) 1997-07-16 1998-04-17 Light detection device
US60/082,253 1998-04-17
US09/062,472 1998-04-17
US8416798P 1998-05-04 1998-05-04
US60/084,167 1998-05-04
US8533598P 1998-05-13 1998-05-13
US60/085,335 1998-05-13
US8550098P 1998-05-14 1998-05-14
US60/085,500 1998-05-14
US8984898P 1998-06-19 1998-06-19
US60/089,848 1998-06-19

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
US09/062,472 Continuation US6071748A (en) 1997-07-16 1998-04-17 Light detection device
US09/118,141 Continuation US6313960B2 (en) 1997-07-16 1998-07-16 Optical filter holder assembly

Related Child Applications (9)

Application Number Title Priority Date Filing Date
US09/062,472 Continuation US6071748A (en) 1997-07-16 1998-04-17 Light detection device
US09/118,141 Continuation US6313960B2 (en) 1997-07-16 1998-07-16 Optical filter holder assembly
US09/118,341 Continuation US6025985A (en) 1997-07-16 1998-07-16 Moveable control unit for high-throughput analyzer
US09/118,310 Continuation US6033100A (en) 1997-07-16 1998-07-16 Floating head assembly
US09/144,575 Continuation US6159425A (en) 1997-07-16 1998-08-31 Sample transporter
US09/144,578 Continuation US6499366B1 (en) 1997-07-16 1998-08-31 Sample feeder
US09/146,081 Continuation US6187267B1 (en) 1997-07-16 1998-09-02 Chemiluminescence detection device
US09/160,533 Continuation US6097025A (en) 1997-07-16 1998-09-24 Light detection device having an optical-path switching mechanism
US09/733,370 Continuation US20010007640A1 (en) 1997-07-16 2000-12-08 Sample transporter

Publications (3)

Publication Number Publication Date
WO1999004228A2 WO1999004228A2 (fr) 1999-01-28
WO1999004228A3 true WO1999004228A3 (fr) 1999-04-01
WO1999004228A9 WO1999004228A9 (fr) 1999-07-08

Family

ID=27584468

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/014575 WO1999004228A2 (fr) 1997-07-16 1998-07-15 Dispositif de detection de lumiere

Country Status (5)

Country Link
US (8) US6071748A (fr)
EP (1) EP1012579A2 (fr)
JP (1) JP2002509235A (fr)
IL (1) IL134069A0 (fr)
WO (1) WO1999004228A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6991765B2 (en) 2000-11-17 2006-01-31 Flir Systems Boston, Inc. Apparatus and methods for infrared calorimetric measurements
US7887752B2 (en) 2003-01-21 2011-02-15 Illumina, Inc. Chemical reaction monitor

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US20030054543A1 (en) * 1997-06-16 2003-03-20 Lafferty William Michael Device for moving a selected station of a holding plate to a predetermined location for interaction with a probe
US6469311B1 (en) * 1997-07-16 2002-10-22 Molecular Devices Corporation Detection device for light transmitted from a sensed volume
US6071748A (en) 1997-07-16 2000-06-06 Ljl Biosystems, Inc. Light detection device
US6258326B1 (en) 1997-09-20 2001-07-10 Ljl Biosystems, Inc. Sample holders with reference fiducials
US7632651B2 (en) 1997-09-15 2009-12-15 Mds Analytical Technologies (Us) Inc. Molecular modification assays
US7070921B2 (en) 2000-04-28 2006-07-04 Molecular Devices Corporation Molecular modification assays
US7745142B2 (en) 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US6982431B2 (en) * 1998-08-31 2006-01-03 Molecular Devices Corporation Sample analysis systems
US6326605B1 (en) 1998-02-20 2001-12-04 Ljl Biosystems, Inc. Broad range light detection system
US6576476B1 (en) * 1998-09-02 2003-06-10 Ljl Biosystems, Inc. Chemiluminescence detection method and device
US6992761B2 (en) * 1997-09-20 2006-01-31 Molecular Devices Corporation Broad range light detection system
US6825921B1 (en) 1999-11-10 2004-11-30 Molecular Devices Corporation Multi-mode light detection system
US6297018B1 (en) * 1998-04-17 2001-10-02 Ljl Biosystems, Inc. Methods and apparatus for detecting nucleic acid polymorphisms
WO2000055372A1 (fr) * 1999-03-16 2000-09-21 Ljl Biosystems, Inc. Procedes et dispositif servant a detecter des polymorphismes d'acides nucleiques
WO2000006991A2 (fr) 1998-07-27 2000-02-10 Ljl Biosystems, Inc. Appareil et procedes de mesures spectroscopiques
WO2000006990A2 (fr) 1998-07-27 2000-02-10 Ljl Biosystems, Inc. Appareil et des procedes de mesures spectroscopiques a resolution temporelle
US6486947B2 (en) * 1998-07-22 2002-11-26 Ljl Biosystems, Inc. Devices and methods for sample analysis
JP3731700B2 (ja) * 1997-12-25 2006-01-05 興和株式会社 蛍光粒子撮像装置
ES2350702T3 (es) * 1998-01-12 2011-01-26 Massachusetts Institute Of Technology Sistema para analizar una pluralidad de muestras.
US6893877B2 (en) 1998-01-12 2005-05-17 Massachusetts Institute Of Technology Methods for screening substances in a microwell array
US6493600B1 (en) * 1998-02-05 2002-12-10 Canon Kabushiki Kaisha Semiconductor manufacturing apparatus
WO1999067641A2 (fr) 1998-06-24 1999-12-29 Illumina, Inc. Decodage de detecteurs matriciels a microspheres
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US6499366B1 (en) 2002-12-31
US6159425A (en) 2000-12-12
US6071748A (en) 2000-06-06
JP2002509235A (ja) 2002-03-26
US20010021074A1 (en) 2001-09-13
WO1999004228A2 (fr) 1999-01-28
WO1999004228A9 (fr) 1999-07-08
US6313960B2 (en) 2001-11-06
US6187267B1 (en) 2001-02-13
IL134069A0 (en) 2001-04-30
US6033100A (en) 2000-03-07
EP1012579A2 (fr) 2000-06-28
US20010007640A1 (en) 2001-07-12
US6025985A (en) 2000-02-15

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