[go: up one dir, main page]

WO1988008843A3 - Nouveaux imidazoles - Google Patents

Nouveaux imidazoles Download PDF

Info

Publication number
WO1988008843A3
WO1988008843A3 PCT/EP1988/000368 EP8800368W WO8808843A3 WO 1988008843 A3 WO1988008843 A3 WO 1988008843A3 EP 8800368 W EP8800368 W EP 8800368W WO 8808843 A3 WO8808843 A3 WO 8808843A3
Authority
WO
WIPO (PCT)
Prior art keywords
alkyl
alkoxycarbonyl
alkoxy
halogen
butenylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP1988/000368
Other languages
German (de)
English (en)
Other versions
WO1988008843A2 (fr
Inventor
Joerg Senn-Bilfinger
Gerhard Grundler
Hartmann Shaefer
Kurt Klemm
Georg Rainer
Richard Riedel
Christian Schudt
Wolfgang Simon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Publication of WO1988008843A2 publication Critical patent/WO1988008843A2/fr
Publication of WO1988008843A3 publication Critical patent/WO1988008843A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Composés de formule (I), dans laquelle R1 est H, halogène, alkyl, alkoxy, alkoxycarbonyle ou cyanogène, R2 est H, alkyl, hydroxyalkyl, haloalkyl, cyanoalkyl ou alkoxycarbonyle, R3 est H, alkyl, formyl, hydroxyalkyl, haloalkyl, cyanoalkyl, aminoalkyl, mono- ou dialkylaminoalkyl, nitroso, nitro, amino, mono- ou dialkylamino ou alkoxycarbonyle, R4 est H, alkyl, alkoxy, halogène ou trifluorométhyle, R5 est H, alkyl, alkoxy, halogène ou trifluorométhyle, R6 est H ou alkyl, n est 1 ou 2, G1 est CH ou N, G2 est O, NH, N-alkyl, S, (=CH-) ou alkylène, G3 est éthylène, triméthylène, tétraméthylène, pentaméthylène, propénylène, 1-buténylène ou 2-buténylène, G4 est S, O ou (-CH=CH-). Ces composés ont des propriétés pharmacologiques intéressantes. Ils ont en particulier un effet protecteur de l'estomac et des intestins d'animaux homéothermes.
PCT/EP1988/000368 1987-05-08 1988-05-04 Nouveaux imidazoles Ceased WO1988008843A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH177187 1987-05-08
CH1771/87-0 1987-05-08

Publications (2)

Publication Number Publication Date
WO1988008843A2 WO1988008843A2 (fr) 1988-11-17
WO1988008843A3 true WO1988008843A3 (fr) 1988-12-01

Family

ID=4218204

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1988/000368 Ceased WO1988008843A2 (fr) 1987-05-08 1988-05-04 Nouveaux imidazoles

Country Status (6)

Country Link
EP (1) EP0290003A3 (fr)
AU (1) AU1686088A (fr)
IL (1) IL86269A0 (fr)
PT (1) PT87426B (fr)
WO (1) WO1988008843A2 (fr)
ZA (1) ZA883169B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990005136A1 (fr) * 1988-11-07 1990-05-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Imidazopyridines
US5716964A (en) * 1989-12-04 1998-02-10 G.D. Searle & Co. Tetrazolyl substituted imidazo 1,2-a!pyridinylalkyl compounds for treatment of neurotoxic injury
KR910011852A (ko) * 1989-12-04 1991-08-07 폴 디. 매튜카이티스 신경독 장해 치료용 이미다조[1,2-a]피리디닐알킬 화합물
IE904346A1 (en) * 1989-12-04 1991-06-05 Searle & Co IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF¹NEUROTOXIC INJURY
WO1992006979A1 (fr) * 1990-10-15 1992-04-30 Byk Gulden Lomberg Chemische Fabrik Gmbh Nouvelles diazines
DE10145457A1 (de) 2001-09-14 2003-04-03 Basf Ag Substituierte Imidazo[1,2-a]-5,6,7,8-tetrahydropyridin-8-one, Verfahren zu ihrer Herstellung, sowie deren Verwendung zur Herstellung von Imidazo[1,2,-a]pyridinen
MXPA05005117A (es) * 2002-11-19 2005-07-01 Altana Pharma Ag Imidazopiridinas 8-sustituidas.
WO2007026218A2 (fr) * 2005-09-01 2007-03-08 Pfizer Japan Inc. Derives de 2-alkyl imidazopyridine a substitution chromane

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068378A1 (fr) * 1981-06-26 1983-01-05 Schering Corporation Imidazo(1,2-a)pyridines et pyrazines, procédés pour leur préparation et composés pharmaceutiques les contenant
EP0033094B1 (fr) * 1980-01-23 1984-10-10 Schering Corporation Imidazo (1,2-a) pyridines, procédés pour leur préparation et compositions pharmaceutiques les contenant
EP0204285B1 (fr) * 1985-06-04 1992-01-15 Fujisawa Pharmaceutical Co., Ltd. Composés imidazohétérocycliques, procédés pour leur préparation et compositions pharmaceutiques les contenant

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0033094B1 (fr) * 1980-01-23 1984-10-10 Schering Corporation Imidazo (1,2-a) pyridines, procédés pour leur préparation et compositions pharmaceutiques les contenant
EP0068378A1 (fr) * 1981-06-26 1983-01-05 Schering Corporation Imidazo(1,2-a)pyridines et pyrazines, procédés pour leur préparation et composés pharmaceutiques les contenant
EP0204285B1 (fr) * 1985-06-04 1992-01-15 Fujisawa Pharmaceutical Co., Ltd. Composés imidazohétérocycliques, procédés pour leur préparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
EP0290003A2 (fr) 1988-11-09
EP0290003A3 (fr) 1988-12-28
IL86269A0 (en) 1988-11-15
AU1686088A (en) 1988-12-06
WO1988008843A2 (fr) 1988-11-17
PT87426B (pt) 1992-09-30
ZA883169B (en) 1988-11-08
PT87426A (pt) 1989-05-31

Similar Documents

Publication Publication Date Title
HUT53090A (en) Process for producing oxo-derivatives of pyridazine, triazine, oxodiazine and thiadiazine
TW239140B (fr)
GR3034146T3 (en) Method of making camptothecin and camptothecin analogs.
DE69120100D1 (de) Annelierte Thiophen-Derivate, ihre Herstellung und Verwendung
YU27204A (sh) Heterociklična jedinjenja koja se upotrebljavaju u tretmanu poremećaja urinarnog trakta
NZ238956A (en) 3-arylindole or 3-arylindazole derivatives and medicaments thereof.
WO1988008843A3 (fr) Nouveaux imidazoles
GR3031693T3 (en) Bicyclic amidine derivatives as inhibitors of nitric oxide synthetase
GR3001584T3 (en) Antiallergy and antiinflammatory agents
MY102973A (en) Isoindolinyl alkyl piperazines
GB8914797D0 (en) Fungicides
MA20002A1 (fr) Nouveaux composes heterocycliques et leur preparation
ES8802499A1 (es) Procedimiento para la obtencion de 1-aril-4-nitropirazoles
ES8607311A1 (es) Un procedimiento para la preparacion de compuestos aminoheterociclicos.
AU2175083A (en) 2-(substituted amino)-pyrimid-4-one derivatives
NZ333229A (fr)
ZA945773B (en) Pharmaceuticals
SG49680A1 (en) Medicament for the inducement of cognition enhancement
IL77601A (en) Propanol derivatives
DK1068199T3 (da) N-Aryloxyethyl-indolyl-alkylaminer til behandling af depression

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AU DK FI HU JP KR NO US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE FR GB IT LU NL SE

AK Designated states

Kind code of ref document: A3

Designated state(s): AU DK FI HU JP KR NO US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE FR GB IT LU NL SE