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UY38925A - Procedimiento para la preparación del ácido 5-bromo-2-(3-cloro-piridin-2-il)-2h-pirazol-3-carboxílico - Google Patents

Procedimiento para la preparación del ácido 5-bromo-2-(3-cloro-piridin-2-il)-2h-pirazol-3-carboxílico

Info

Publication number
UY38925A
UY38925A UY0001038925A UY38925A UY38925A UY 38925 A UY38925 A UY 38925A UY 0001038925 A UY0001038925 A UY 0001038925A UY 38925 A UY38925 A UY 38925A UY 38925 A UY38925 A UY 38925A
Authority
UY
Uruguay
Prior art keywords
bromo
chloro
pirazol
pyridin
procedure
Prior art date
Application number
UY0001038925A
Other languages
English (en)
Inventor
Yanchun Cao
Xin Liu
Jianhua Mao
Zhijian Xu
Original Assignee
Fmc Corp
Fmc Agro Singapore Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp, Fmc Agro Singapore Pte Ltd filed Critical Fmc Corp
Publication of UY38925A publication Critical patent/UY38925A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

En la presente se describen procedimientos novedosos para sintetizar el ácido 5-bromo-2-(3-cloro-pirazol-2-il)-2H-pirazol-3-carboxílico a partir de pirazol o derivados de pirazol. En la presente también se describen compuestos intermedios de la reacción novedosos.
UY0001038925A 2019-10-18 2020-10-16 Procedimiento para la preparación del ácido 5-bromo-2-(3-cloro-piridin-2-il)-2h-pirazol-3-carboxílico UY38925A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962916840P 2019-10-18 2019-10-18
US202062982248P 2020-02-27 2020-02-27

Publications (1)

Publication Number Publication Date
UY38925A true UY38925A (es) 2021-05-31

Family

ID=73198483

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001038925A UY38925A (es) 2019-10-18 2020-10-16 Procedimiento para la preparación del ácido 5-bromo-2-(3-cloro-piridin-2-il)-2h-pirazol-3-carboxílico

Country Status (16)

Country Link
US (2) US20220396560A1 (es)
EP (5) EP4043451B1 (es)
JP (2) JP2022552273A (es)
KR (2) KR20220086612A (es)
CN (3) CN114641471B (es)
AU (2) AU2020366037A1 (es)
BR (2) BR112022007215A2 (es)
HU (4) HUE062047T2 (es)
IL (5) IL291939B2 (es)
MA (2) MA56055A (es)
MX (2) MX2022004631A (es)
PL (4) PL4043451T3 (es)
TW (3) TWI875840B (es)
UY (1) UY38925A (es)
WO (2) WO2021076839A1 (es)
ZA (2) ZA202204278B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112022007294A2 (pt) * 2019-10-18 2022-07-05 Fmc Corp Métodos para a preparação de ácido 5-bromo-2-(3-cloro-piridin-2-il)-2h-pirazol-3-carboxílico
PL4043451T3 (pl) * 2019-10-18 2024-06-10 Fmc Corporation Sposoby wytwarzania związku pośredniego w syntezie kwasu 5-bromo-2-(3-chloropirydyn-2-ylo)-2h-pirazolo-3-karboksylowego
CN115557931B (zh) * 2022-10-20 2024-05-14 浙江新安化工集团股份有限公司 一种3-溴-1-(3-氯-2-吡啶基)-1h-吡唑-5-甲酸的合成方法
CN117024374A (zh) * 2023-08-08 2023-11-10 安庆百谊生物科技有限公司 一种3-甲基-1，2，4-噻二唑-5-碳酰肼或其盐的合成方法

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UA115881C2 (uk) * 2012-09-07 2018-01-10 Бьорінгер Інгельхайм Інтернаціональ Гмбх Алкоксипіразоли як активатори розчинної гуанілатциклази
CN105669643A (zh) * 2013-12-05 2016-06-15 江西天人生态股份有限公司 一类基于鱼泥丁受体的邻甲酰氨基苯甲酰胺衍生物及其制备方法和用途
BR112016023860A2 (pt) * 2014-04-14 2017-08-15 Gruenenthal Gmbh heterociclil sulfonas substituídas por heteroaril
TW201726128A (zh) * 2015-10-08 2017-08-01 歌林達有限公司 經吡唑基取代之四氫哌喃基碸
EP3371176A4 (en) * 2015-10-16 2019-09-04 William Marsh Rice University EPOTHILON ANALOGUE, SYNTHESIS METHOD, TREATMENT METHOD AND MEDICAMENT CONJUGATE THEREFOR
DK3558945T3 (da) * 2016-12-21 2021-07-26 Bayer Cropscience Ag Fremgangsmåde til fremstilling af et n-[2-(2-pyridinyl)ethyl]carboxamidderivat
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CN111825653A (zh) * 2019-04-19 2020-10-27 安道麦马克西姆有限公司 取代吡唑类化合物的制备及其作为邻氨基苯甲酰胺前体的用途
PL4043451T3 (pl) 2019-10-18 2024-06-10 Fmc Corporation Sposoby wytwarzania związku pośredniego w syntezie kwasu 5-bromo-2-(3-chloropirydyn-2-ylo)-2h-pirazolo-3-karboksylowego

Also Published As

Publication number Publication date
ZA202204278B (en) 2024-08-28
PL3976589T3 (pl) 2023-07-31
KR20220086612A (ko) 2022-06-23
PL4043451T3 (pl) 2024-06-10
EP4219455A1 (en) 2023-08-02
TW202128631A (zh) 2021-08-01
CN119039270A (zh) 2024-11-29
IL299818B2 (en) 2025-02-01
JP2022552272A (ja) 2022-12-15
CN114641471A (zh) 2022-06-17
IL294551A (en) 2022-09-01
TW202517625A (zh) 2025-05-01
HUE066520T2 (hu) 2024-08-28
IL298694A (en) 2023-02-01
EP3976589B1 (en) 2023-04-12
WO2021076839A1 (en) 2021-04-22
CN114650987A (zh) 2022-06-21
EP4043451A1 (en) 2022-08-17
HUE062237T2 (hu) 2023-10-28
WO2021076835A1 (en) 2021-04-22
EP3976591A1 (en) 2022-04-06
KR20220084347A (ko) 2022-06-21
IL291939A (en) 2022-06-01
EP4219455B1 (en) 2024-12-11
EP4253380A2 (en) 2023-10-04
EP4043451B1 (en) 2024-02-28
PL3976591T3 (pl) 2023-07-31
CN114650987B (zh) 2024-09-06
TWI875840B (zh) 2025-03-11
IL294551B1 (en) 2023-01-01
IL292090A (en) 2022-06-01
MX2022004631A (es) 2022-05-24
WO2021076835A8 (en) 2021-11-04
PL4219455T3 (pl) 2025-04-14
AU2020366037A1 (en) 2022-04-21
MX2022004627A (es) 2022-05-26
HUE070680T2 (hu) 2025-06-28
BR112022007102A2 (pt) 2022-07-05
US20220396560A1 (en) 2022-12-15
ZA202204277B (en) 2024-08-28
JP7667144B2 (ja) 2025-04-22
MA56053A (fr) 2022-04-20
IL292090B2 (en) 2023-06-01
EP3976589A1 (en) 2022-04-06
EP4253380A3 (en) 2023-11-15
IL299818B1 (en) 2024-10-01
MA56055A (fr) 2022-04-06
BR112022007215A2 (pt) 2022-07-05
JP2022552273A (ja) 2022-12-15
TW202116748A (zh) 2021-05-01
IL298694B2 (en) 2025-05-01
IL291939B (en) 2022-12-01
IL291939B2 (en) 2023-04-01
TWI884994B (zh) 2025-06-01
CN114641471B (zh) 2025-05-23
EP3976591B1 (en) 2023-04-19
AU2020366212A1 (en) 2022-04-21
US20220259178A1 (en) 2022-08-18
IL299818A (en) 2023-03-01
HUE062047T2 (hu) 2023-09-28
IL294551B2 (en) 2023-05-01
IL298694B1 (en) 2025-01-01

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