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UY28513A1 - Nuevos compuestos - Google Patents

Nuevos compuestos

Info

Publication number
UY28513A1
UY28513A1 UY28513A UY28513A UY28513A1 UY 28513 A1 UY28513 A1 UY 28513A1 UY 28513 A UY28513 A UY 28513A UY 28513 A UY28513 A UY 28513A UY 28513 A1 UY28513 A1 UY 28513A1
Authority
UY
Uruguay
Prior art keywords
new compounds
compounds
racemates
tautomers
therapy
Prior art date
Application number
UY28513A
Other languages
English (en)
Inventor
Hansen Peter
Lonn Hans
Lawitz Karolina
Nikitidis Antonios
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29212489&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY28513(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY28513A1 publication Critical patent/UY28513A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se proporcionaron compuestos nuevos de fórmula (I) en donde R1, R2, R4, R5, G1, G2, L, Y y n son como se define en la memoria descriptiva e isómeros, racematos y tautómeros ópticos de los mismos; junto con procesos para su preparación, composiciones que los contienen y su uso en terapia. Los compuestos son inhibidores de la elastasa de neutrófilo.
UY28513A 2003-09-18 2004-09-15 Nuevos compuestos UY28513A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0302487A SE0302487D0 (sv) 2003-09-18 2003-09-18 Novel compounds

Publications (1)

Publication Number Publication Date
UY28513A1 true UY28513A1 (es) 2005-04-29

Family

ID=29212489

Family Applications (1)

Application Number Title Priority Date Filing Date
UY28513A UY28513A1 (es) 2003-09-18 2004-09-15 Nuevos compuestos

Country Status (25)

Country Link
US (1) US20070043036A1 (es)
EP (1) EP1663974B1 (es)
JP (1) JP2007505902A (es)
KR (1) KR20060096995A (es)
CN (1) CN100439339C (es)
AR (1) AR046083A1 (es)
AT (1) ATE420861T1 (es)
AU (1) AU2004272485B2 (es)
BR (1) BRPI0414570A (es)
CA (1) CA2538410A1 (es)
CO (1) CO5670357A2 (es)
DE (1) DE602004019110D1 (es)
ES (1) ES2319300T3 (es)
IL (1) IL173986A0 (es)
IS (1) IS8394A (es)
MX (1) MXPA06002723A (es)
NO (1) NO20061700L (es)
RU (1) RU2348617C2 (es)
SA (1) SA04250300B1 (es)
SE (1) SE0302487D0 (es)
TW (1) TW200526579A (es)
UA (1) UA84878C2 (es)
UY (1) UY28513A1 (es)
WO (1) WO2005026124A1 (es)
ZA (1) ZA200602262B (es)

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US7439246B2 (en) 2004-06-28 2008-10-21 Bristol-Myers Squibb Company Fused heterocyclic kinase inhibitors
TW200700392A (en) * 2005-03-16 2007-01-01 Astrazeneca Ab Novel compounds
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TW200808771A (en) * 2006-05-08 2008-02-16 Astrazeneca Ab Novel compounds II
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CN108137542B (zh) 2015-09-02 2023-10-27 葛兰素史克知识产权第二有限公司 用作溴结构域抑制剂的吡啶酮二甲酰胺
TW201720828A (zh) 2015-11-23 2017-06-16 赫孚孟拉羅股份公司 治療性化合物及組合物以及其使用方法
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CN109476638B (zh) 2016-05-05 2021-12-28 豪夫迈·罗氏有限公司 吡唑衍生物、其组合物及治疗用途
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JP2020510061A (ja) 2017-03-14 2020-04-02 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ピラゾロクロロフェニル化合物、組成物及びその使用方法
CR20190520A (es) 2017-05-22 2020-01-21 Hoffmann La Roche Composiciones y compuestos terapéuticos y métodos para utilizarlos
JP7228318B6 (ja) 2017-05-22 2023-03-10 エフ． ホフマン－ラ ロシュ アーゲー 処置用化合物及び組成物、並びにその使用方法
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CN111587250A (zh) 2018-01-15 2020-08-25 豪夫迈·罗氏有限公司 作为jak抑制剂的吡唑并嘧啶化合物
CN111683976B (zh) 2018-02-05 2022-11-18 生物辐射实验室股份有限公司 具有阴离子交换-疏水混合模式配体的色谱树脂
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CN110192947B (zh) * 2019-05-28 2022-01-04 河南省超亚医药器械有限公司 一种小儿肺部热敷贴
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Also Published As

Publication number Publication date
BRPI0414570A (pt) 2006-11-07
KR20060096995A (ko) 2006-09-13
EP1663974A1 (en) 2006-06-07
MXPA06002723A (es) 2006-06-06
WO2005026124A1 (en) 2005-03-24
RU2348617C2 (ru) 2009-03-10
IS8394A (is) 2006-03-31
ES2319300T3 (es) 2009-05-06
CN100439339C (zh) 2008-12-03
CO5670357A2 (es) 2006-08-31
SE0302487D0 (sv) 2003-09-18
UA84878C2 (ru) 2008-12-10
AU2004272485A1 (en) 2005-03-24
JP2007505902A (ja) 2007-03-15
EP1663974B1 (en) 2009-01-14
IL173986A0 (en) 2006-07-05
AU2004272485B2 (en) 2008-03-13
ATE420861T1 (de) 2009-01-15
DE602004019110D1 (de) 2009-03-05
ZA200602262B (en) 2007-07-25
NO20061700L (no) 2006-04-18
AR046083A1 (es) 2005-11-23
CA2538410A1 (en) 2005-03-24
RU2006112427A (ru) 2007-11-10
CN1856467A (zh) 2006-11-01
SA04250300B1 (ar) 2008-09-07
US20070043036A1 (en) 2007-02-22
TW200526579A (en) 2005-08-16
HK1089167A1 (en) 2006-11-24

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