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UY25344A1 - Procedimiento para la preparacion de derivados de la tienopirimidina y de la tienopiridina utiles como agentes anticancerigenos - Google Patents

Procedimiento para la preparacion de derivados de la tienopirimidina y de la tienopiridina utiles como agentes anticancerigenos

Info

Publication number
UY25344A1
UY25344A1 UY25344A UY25344A UY25344A1 UY 25344 A1 UY25344 A1 UY 25344A1 UY 25344 A UY25344 A UY 25344A UY 25344 A UY25344 A UY 25344A UY 25344 A1 UY25344 A1 UY 25344A1
Authority
UY
Uruguay
Prior art keywords
preparation
tienopyrimidine
tienopyridine
procedure
cancer agents
Prior art date
Application number
UY25344A
Other languages
English (en)
Inventor
John Munchhof Michael
Beth Sobolov-Jaynes Susan
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of UY25344A1 publication Critical patent/UY25344A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Esta invención se refiere a derivados biciclicos de pirimidina y de piridina de fórmula l que son utiles en el tratamiento de enfermedades hiperporliferativas, como cánceres en mamíferos. Un método para la preparación del compuesto de fórmula l (como por ejemplo: (3 etinil fenil)(6-fenil tieno[3,2 d]pirimidin 4-il]amina) o una sal farmacéuticamente aceptable o hidrato del mismo donde: X1 es N o CH; R1 es H; R2 es C6-C10 arilo o hetericiclico de 5-13 miembros, donde los referidos grupos R2 son opcionalmente sustituidos por 1 o 5 sustituyentes R5.
UY25344A 1997-11-11 1999-01-11 Procedimiento para la preparacion de derivados de la tienopirimidina y de la tienopiridina utiles como agentes anticancerigenos UY25344A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6509797P 1997-11-11 1997-11-11
UY25238A UY25238A1 (es) 1997-11-11 1998-11-09 Derivados de la tienopirimidina y de la tienopiridina útiles como agentes anticancerigenos.

Publications (1)

Publication Number Publication Date
UY25344A1 true UY25344A1 (es) 1999-09-27

Family

ID=22060322

Family Applications (2)

Application Number Title Priority Date Filing Date
UY25238A UY25238A1 (es) 1997-11-11 1998-11-09 Derivados de la tienopirimidina y de la tienopiridina útiles como agentes anticancerigenos.
UY25344A UY25344A1 (es) 1997-11-11 1999-01-11 Procedimiento para la preparacion de derivados de la tienopirimidina y de la tienopiridina utiles como agentes anticancerigenos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
UY25238A UY25238A1 (es) 1997-11-11 1998-11-09 Derivados de la tienopirimidina y de la tienopiridina útiles como agentes anticancerigenos.

Country Status (37)

Country Link
US (1) US6492383B1 (es)
EP (1) EP1028964A1 (es)
JP (1) JP2001522853A (es)
KR (1) KR100446363B1 (es)
CN (2) CN101328186A (es)
AP (1) AP976A (es)
AR (1) AR018517A1 (es)
AU (1) AU9454198A (es)
BG (1) BG65180B1 (es)
BR (1) BR9814018A (es)
CA (1) CA2309690A1 (es)
CO (1) CO4990956A1 (es)
CZ (1) CZ20001709A3 (es)
DZ (1) DZ2646A1 (es)
EA (1) EA005889B1 (es)
GT (1) GT199800180A (es)
HN (1) HN1998000168A (es)
HR (1) HRP20000286A2 (es)
HU (1) HUP0100287A3 (es)
ID (1) ID23978A (es)
IL (1) IL135636A0 (es)
IS (1) IS5464A (es)
MA (1) MA24694A1 (es)
MY (1) MY132073A (es)
NO (1) NO20002162L (es)
NZ (1) NZ520093A (es)
OA (1) OA11376A (es)
PA (1) PA8462401A1 (es)
PE (1) PE129099A1 (es)
PL (1) PL340589A1 (es)
SK (1) SK6652000A3 (es)
TN (1) TNSN98203A1 (es)
TW (1) TW593321B (es)
UA (1) UA72881C2 (es)
UY (2) UY25238A1 (es)
WO (1) WO1999024440A1 (es)
ZA (1) ZA9810253B (es)

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