UY25191A1 - Derivados de resorcinol - Google Patents
Derivados de resorcinolInfo
- Publication number
- UY25191A1 UY25191A1 UY25191A UY25191A UY25191A1 UY 25191 A1 UY25191 A1 UY 25191A1 UY 25191 A UY25191 A UY 25191A UY 25191 A UY25191 A UY 25191A UY 25191 A1 UY25191 A1 UY 25191A1
- Authority
- UY
- Uruguay
- Prior art keywords
- skin
- compound
- water
- emulsion
- lightening
- Prior art date
Links
- GHMLBKRAJCXXBS-UHFFFAOYSA-N resorcinol Chemical class OC1=CC=CC(O)=C1 GHMLBKRAJCXXBS-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 abstract 2
- 208000012641 Pigmentation disease Diseases 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000012049 topical pharmaceutical composition Substances 0.000 abstract 2
- 150000005207 1,3-dihydroxybenzenes Chemical class 0.000 abstract 1
- LSEHCENPUMUIKC-UHFFFAOYSA-N 4-cyclohexylbenzene-1,3-diol Chemical compound OC1=CC(O)=CC=C1C1CCCCC1 LSEHCENPUMUIKC-UHFFFAOYSA-N 0.000 abstract 1
- IXMNGROEFGBSGO-UHFFFAOYSA-N 4-cyclopentylbenzene-1,3-diol Chemical compound OC1=CC(O)=CC=C1C1CCCC1 IXMNGROEFGBSGO-UHFFFAOYSA-N 0.000 abstract 1
- 241000021559 Dicerandra Species 0.000 abstract 1
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 235000010654 Melissa officinalis Nutrition 0.000 abstract 1
- QNVSXXGDAPORNA-UHFFFAOYSA-N Resveratrol Natural products OC1=CC=CC(C=CC=2C=C(O)C(O)=CC=2)=C1 QNVSXXGDAPORNA-UHFFFAOYSA-N 0.000 abstract 1
- LUKBXSAWLPMMSZ-OWOJBTEDSA-N Trans-resveratrol Chemical compound C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC(O)=C1 LUKBXSAWLPMMSZ-OWOJBTEDSA-N 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 235000006708 antioxidants Nutrition 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000008395 clarifying agent Substances 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 239000000499 gel Substances 0.000 abstract 1
- 239000008273 gelatin Substances 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000865 liniment Substances 0.000 abstract 1
- 239000006210 lotion Substances 0.000 abstract 1
- -1 mask Substances 0.000 abstract 1
- 239000004005 microsphere Substances 0.000 abstract 1
- 239000008267 milk Substances 0.000 abstract 1
- 235000013336 milk Nutrition 0.000 abstract 1
- 210000004080 milk Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002077 nanosphere Substances 0.000 abstract 1
- 239000007764 o/w emulsion Substances 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 239000006072 paste Substances 0.000 abstract 1
- 230000019612 pigmentation Effects 0.000 abstract 1
- 235000021283 resveratrol Nutrition 0.000 abstract 1
- 229940016667 resveratrol Drugs 0.000 abstract 1
- 229930002330 retinoic acid Natural products 0.000 abstract 1
- 230000000475 sunscreen effect Effects 0.000 abstract 1
- 239000000516 sunscreening agent Substances 0.000 abstract 1
- 229960001727 tretinoin Drugs 0.000 abstract 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 abstract 1
- 239000007762 w/o emulsion Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/915—Therapeutic or pharmaceutical composition
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/926—Topical chemical, e.g. cosmetic or sunscreen
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se refiere al uso de ciertos derivados de resorcinol como agentes clarificadores de la piel. La presente invención a una composición farmacéutica tópica para aclarar la piel o rducir la pigmentación de la piel en un ser humano, que comprende una cantidad entre 0.01 y 10% en peso de un compuesto de fórmula (I), en el que: X es hidrógeno, alquilo, cicloalquilo, alquilo-arilo; n es de 0 a 3; la línea punteada representa un enlace doble opcional; ó una sal farmacéuticamente aceptable del mismo. Dicha cantidad del compuesto de fórmula o de la sal farmacéuticamente aceptable del mismo es eficaz en el aclaramiento de la piel o en la reducción de la pigmentación de la eel; y un vehículo farmacéutico aceptable. Esta composición se presenta en forma de una solución de agua-alcohol, una emulsión de aceite en agua, una emulsión de agua en aceite, un gel en forma de emulsión, o un sistema de dos fases. También como loción, crema, leche, gelatina, pasta, ungüento, bálsamo, máscara, microesferas, nanoesferas o una dispersión vesicular. Los preferidos como compuesto (I) son: 4-ciclohexilresorcinol; 4-ciclopentilresorcinol. La composición farmacéutica tópica además puede comprender una pantalla solar, resveratrol u otro agente activo antioxidante, ácido retinóico o un derivado del mismo, ácido glicólico, ácido tricloroacético u otro agente exfoliante de la piel.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5962597P | 1997-09-23 | 1997-09-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY25191A1 true UY25191A1 (es) | 2001-08-27 |
Family
ID=22024176
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY25191A UY25191A1 (es) | 1997-09-23 | 1998-09-23 | Derivados de resorcinol |
| UY25550A UY25550A1 (es) | 1997-09-23 | 1999-06-08 | Procedimiento para preparar derivados de resorcinol |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY25550A UY25550A1 (es) | 1997-09-23 | 1999-06-08 | Procedimiento para preparar derivados de resorcinol |
Country Status (45)
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HN1996000101A (es) | 1996-02-28 | 1997-06-26 | Inc Pfizer | Terapia combinada para la osteoporosis |
| US6414037B1 (en) * | 1998-01-09 | 2002-07-02 | Pharmascience | Pharmaceutical formulations of resveratrol and methods of use thereof |
| FR2777183B1 (fr) * | 1998-04-10 | 2001-03-02 | Oreal | Utilisation d'au moins un hydroxystilbene dans une composition destinee a favoriser la desquamation de la peau et composition le comprenant |
| FR2777186B1 (fr) * | 1998-04-10 | 2001-03-09 | Oreal | Utilisation d'au moins un hydroxystilbene dans une composition raffermissante |
| US6878381B2 (en) * | 1999-03-22 | 2005-04-12 | Pfizer, Inc | Resorcinol composition |
| US6828460B2 (en) * | 1999-03-22 | 2004-12-07 | Pfizer Inc. | Resorcinol derivatives |
| IL144850A0 (en) * | 1999-03-22 | 2002-06-30 | Pfizer | Resorcinol derivatives |
| HN2000000033A (es) * | 1999-03-22 | 2001-02-02 | Pfizer Prod Inc | Composicion de resorcinol |
| US20020034772A1 (en) * | 1999-06-29 | 2002-03-21 | Orlow Seth J. | Methods and compositions that affect melanogenesis |
| EP1134207A1 (en) * | 2000-03-15 | 2001-09-19 | Pfizer Products Inc. | Process for preparing resorcinol derivatives |
| IT1318425B1 (it) * | 2000-03-24 | 2003-08-25 | D B P Dev Biotechnological Pro | Impiego del resveratrolo per il trattamento di eczema desquamativo,acne e psoriasi. |
| JP4615671B2 (ja) * | 2000-04-20 | 2011-01-19 | ポーラ化成工業株式会社 | 炎症存在下使用用のしわ形成又は皮膚の弾力喪失の防止剤 |
| EP1317425B1 (en) * | 2000-09-11 | 2004-11-03 | Pfizer Products Inc. | Resorcinol derivatives |
| JP3950046B2 (ja) * | 2000-09-21 | 2007-07-25 | ファイザー・プロダクツ・インク | レゾルシノール誘導体 |
| US6514506B1 (en) * | 2001-02-14 | 2003-02-04 | Color Access, Inc. | Whitening compositions containing ascomycete derived enzyme |
| JP2004528341A (ja) | 2001-05-02 | 2004-09-16 | ニューヨーク・ユニバーシティ | 脂肪酸合成酵素の阻害による色素形成の阻害 |
| DE50203353D1 (de) | 2001-05-25 | 2005-07-14 | Wella Ag | 1,3-dihydroxybenzol-derivate und diese verbindungen enthaltende färbemittel |
| US6863897B2 (en) * | 2002-03-22 | 2005-03-08 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Stabilization of resorcinol derivatives in cosmetic compositions |
| US6869598B2 (en) * | 2002-03-22 | 2005-03-22 | Unilever Home & Personal Care Usa Division Of Conopco, Inc. | Stabilization of sunscreens in cosmetic compositions |
| US7378232B2 (en) * | 2002-05-09 | 2008-05-27 | New York University | Assay for melanogenesis |
| US7977049B2 (en) * | 2002-08-09 | 2011-07-12 | President And Fellows Of Harvard College | Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms |
| US6852310B2 (en) * | 2002-08-23 | 2005-02-08 | Unilever Home & Personal Care Usa Division Of Conopco, Inc. | Skin lightening agents, compositions and methods |
| US20040109832A1 (en) * | 2002-12-09 | 2004-06-10 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Di-substituted resorcinols as skin lightening agents |
| US7524485B2 (en) * | 2002-12-12 | 2009-04-28 | Unilever Home & Personal Care, Usa, Division Of Conopco, Inc. | Skin lightening agents, compositions and methods |
| US6875425B2 (en) * | 2002-12-12 | 2005-04-05 | Unilever Home & Personal Care Usa | Skin lightening agents, compositions and methods |
| DE602004026272D1 (de) * | 2003-02-03 | 2010-05-12 | Warner Lambert Co | Verbesserte formulierung für hautbleichmittel |
| US7338979B2 (en) * | 2003-02-11 | 2008-03-04 | Warner-Lambert Company | Depigmentation agents |
| DE602004015972D1 (en) * | 2003-05-20 | 2008-10-02 | Warner Lambert Co | Depigmentierungsmittel |
| JP2006528239A (ja) * | 2003-05-26 | 2006-12-14 | エンプラニ シーオー．，エルティーディ． | レスベラトロルを含有する、美白及び抗酸化作用を有する化粧料組成物、並びに、その製造方法 |
| JP2007530417A (ja) | 2003-07-01 | 2007-11-01 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 細胞及び生物の寿命及びストレス応答を操作するための組成物 |
| DE602004017747D1 (de) * | 2003-07-08 | 2008-12-24 | Unilever Nv | Verfahren zur herstellung einer kosmetisch aktiven verbindung |
| US8017634B2 (en) | 2003-12-29 | 2011-09-13 | President And Fellows Of Harvard College | Compositions for treating obesity and insulin resistance disorders |
| CN101247793B (zh) | 2003-12-29 | 2013-04-10 | 哈佛大学校长及研究员协会 | 治疗或预防肥胖和胰岛素抗性病症的组合物 |
| US7300646B2 (en) * | 2004-02-27 | 2007-11-27 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Skin lightening agents, compositions and methods |
| CN109134205B (zh) | 2004-05-28 | 2022-07-19 | 尤尼根公司 | 作为双核酶强效抑制剂的二芳基烷烃 |
| MX2007003126A (es) | 2004-09-14 | 2007-08-02 | Ajinomoto Omnichem S A | Composiciones topicas que contienen polifenoles fosforilados. |
| JP5093998B2 (ja) * | 2004-09-22 | 2012-12-12 | 大塚製薬株式会社 | 色素沈着予防又は改善剤 |
| US20060210497A1 (en) * | 2005-03-18 | 2006-09-21 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Novel resorcinol derivatives |
| US20060210498A1 (en) * | 2005-03-18 | 2006-09-21 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Novel resorcinol derivatives for skin |
| WO2006138418A2 (en) | 2005-06-14 | 2006-12-28 | President And Fellows Of Harvard College | Improvement of cognitive performance with sirtuin activators |
| WO2007077770A1 (ja) * | 2005-12-26 | 2007-07-12 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | アルキルレゾルシノール配糖体とその製造方法並びに用途 |
| EP1973520A1 (en) * | 2006-01-05 | 2008-10-01 | Symrise GmbH & Co. KG | Stabilized preparations comprising phenolic compounds and benzophenones |
| US7270805B1 (en) | 2006-03-30 | 2007-09-18 | Conopco, Inc. | Skin lightening agents, compositions and methods |
| US7247294B1 (en) | 2006-03-30 | 2007-07-24 | Conopco, Inc. | Skin lightening agents, compositions and methods |
| US7250158B1 (en) | 2006-03-30 | 2007-07-31 | Conopco, Inc. | Skin lightening agents, compositions and methods |
| JP5145221B2 (ja) * | 2006-06-19 | 2013-02-13 | 株式会社クラレ | 安定性に優れた皮膚外用剤 |
| JP4990574B2 (ja) * | 2006-07-13 | 2012-08-01 | ポーラ化成工業株式会社 | 新規化合物及びそれを含有する皮膚外用剤 |
| JP5132095B2 (ja) * | 2006-07-13 | 2013-01-30 | ポーラ化成工業株式会社 | エマルション剤形の皮膚外用剤 |
| DE102007038098A1 (de) | 2007-08-13 | 2009-02-19 | Merck Patent Gmbh | Tyrosinaseinhibitoren |
| DE102007038097A1 (de) | 2007-08-13 | 2009-02-19 | Merck Patent Gmbh | Tyrosinaseinhibitoren |
| WO2009064493A1 (en) * | 2007-11-14 | 2009-05-22 | New York University School Of Medicine | Tricyclic compounds as melanogenesis modifiers and uses thereof |
| WO2009064492A1 (en) * | 2007-11-14 | 2009-05-22 | New York University School Of Medicine | Quinoline compounds as melanogenesis modifiers and uses thereof |
| US20100040568A1 (en) * | 2008-04-30 | 2010-02-18 | Skinmedica, Inc. | Steroidal compounds as melanogenesis modifiers and uses thereof |
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