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UY25780A1 - Nuevos antibióticos macrólidos - Google Patents

Nuevos antibióticos macrólidos

Info

Publication number
UY25780A1
UY25780A1 UY25780A UY25780A UY25780A1 UY 25780 A1 UY25780 A1 UY 25780A1 UY 25780 A UY25780 A UY 25780A UY 25780 A UY25780 A UY 25780A UY 25780 A1 UY25780 A1 UY 25780A1
Authority
UY
Uruguay
Prior art keywords
compounds
formula
new
infections
macrolid antibiotics
Prior art date
Application number
UY25780A
Other languages
English (en)
Inventor
Takushi Kaneko
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of UY25780A1 publication Critical patent/UY25780A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Esta invención se refiere a compuestos de fórmula (I) y a sus sales farmacéuticamente aceptables, útiles como potentes agentes antibacterianos y antiprotozoos que se pueden usar para tratar diversas infecciones bacterianas y provocadas por protozoos y trastornos relacionados con dichas infecciones. También se refiere a composiciones farmacéuticas que contienen los compuestos de fórmula (I) y a procedimientos para tratar infecciones bacterianas y provocadas por protozoos administrando los compuestos de fórmula (I).
UY25780A 1998-11-03 1999-10-29 Nuevos antibióticos macrólidos UY25780A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10683698P 1998-11-03 1998-11-03

Publications (1)

Publication Number Publication Date
UY25780A1 true UY25780A1 (es) 2001-08-27

Family

ID=22313524

Family Applications (1)

Application Number Title Priority Date Filing Date
UY25780A UY25780A1 (es) 1998-11-03 1999-10-29 Nuevos antibióticos macrólidos

Country Status (34)

Country Link
US (3) US20020040007A1 (es)
EP (1) EP1124837A2 (es)
JP (1) JP4043191B2 (es)
KR (1) KR20010083944A (es)
CN (1) CN1376160A (es)
AP (1) AP2001002131A0 (es)
AU (1) AU5995299A (es)
BG (1) BG105543A (es)
BR (1) BR9914998A (es)
CA (1) CA2349338C (es)
CO (1) CO5140110A1 (es)
CZ (1) CZ20011512A3 (es)
EA (1) EA200100396A1 (es)
EE (1) EE200100245A (es)
GT (1) GT199900192A (es)
HK (1) HK1049010A1 (es)
HR (1) HRP20010306A2 (es)
HU (1) HUP0104192A3 (es)
ID (1) ID28286A (es)
IL (1) IL142628A0 (es)
IS (1) IS5919A (es)
MA (1) MA26703A1 (es)
NO (1) NO20012155L (es)
OA (1) OA11670A (es)
PA (1) PA8485101A1 (es)
PE (1) PE20001289A1 (es)
PL (1) PL348114A1 (es)
SK (1) SK5812001A3 (es)
SV (1) SV1999000188A (es)
TN (1) TNSN99205A1 (es)
TR (4) TR200200434T2 (es)
UY (1) UY25780A1 (es)
WO (1) WO2000026224A2 (es)
ZA (1) ZA200103289B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP9801420A0 (en) * 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
TR200200434T2 (tr) 1998-11-03 2002-09-23 Pfizer Products Inc. Yeni makrolit antibiyotikler.
ID30233A (id) 1999-01-27 2001-11-15 Pfizer Prod Inc Antibiotika ketolida
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
KR20020007374A (ko) 1999-04-16 2002-01-26 추후제출 매크롤라이드 항감염제
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6399582B1 (en) 1999-04-16 2002-06-04 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
IL145739A0 (en) 1999-05-24 2002-07-25 Pfizer Prod Inc 13-methyl-erythromycin derivatives
EP1114826A3 (en) * 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
DE60104240T2 (de) * 2000-06-30 2005-08-04 Pfizer Products Inc., Groton Makrolid-Antibiotika
JP2008508322A (ja) * 2004-07-28 2008-03-21 ランバクシー ラボラトリーズ リミテッド 抗菌剤としてのケトライド誘導体
US20090170790A1 (en) * 2004-10-25 2009-07-02 Biswajit Das Ketolide derivatives as antibacterial agents
PL1836211T3 (pl) * 2004-12-21 2010-07-30 Pfizer Prod Inc Makrolidy
EP1960413A2 (en) * 2005-11-23 2008-08-27 Ranbaxy Laboratories Limited Macrolides derivatives as antibacterial agents
US20090005325A1 (en) * 2005-11-23 2009-01-01 Biswajit Bas Ketolide Derivatives as Antibacterial Agents
US7801502B2 (en) * 2006-12-18 2010-09-21 Aai Corporation Method for implementing continuous radio frequency (RF) alignment in advanced electronic warfare (EW) signal stimulation systems
US8409628B2 (en) 2010-02-04 2013-04-02 Penguin IP Holdings, Inc. Methods and compositions for oxygenation of skin to treat skin disorders
WO2011123619A2 (en) 2010-03-31 2011-10-06 Penguin Ip Holdings Inc. Permeable mixtures, methods and compositions for the skin
US9539223B2 (en) * 2013-05-01 2017-01-10 Neoculi Pty Ltd Methods for treating bacterial infections
RU2537143C1 (ru) * 2013-11-08 2014-12-27 Государственное научное учреждение Ставропольский научно-исследовательский институт животноводства и кормопроизводства РАСХН Препарат для лечения и профилактики мастита у коров
WO2018080072A2 (ko) * 2016-10-27 2018-05-03 한국생명공학연구원 신규한 매크로라이드계 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 말라리아의 예방 또는 치료용 약학적 조성물

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YU43006B (en) * 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of erythromycin derivatives
FR2697524B1 (fr) 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5527780A (en) 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
US5332807A (en) 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
FR2702480B1 (fr) * 1993-03-09 1995-04-28 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
HRP931480B1 (en) 1993-12-08 1997-08-31 Sour Pliva 9a-N-(N'-CARBAMONYL) and 9a-N-(N'-THIOCARBAMONYL) DERIVATES OF 9-DEOXO-9a-HOMOERYTHROMYCIN A
HRP950145A2 (en) * 1995-03-27 1997-08-31 Sour Pliva New compounds of the secomacrolide and secoazalide class and a process for the preparation thereof
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AU731301B2 (en) 1996-07-05 2001-03-29 Biotica Technology Limited Erythromycins and process for their preparation
UA51730C2 (uk) 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
DE69733723T2 (de) 1996-09-04 2006-04-20 Abbott Laboratories, Abbott Park 6-o-Substituierte Ketoliden mit antibakteriellen Wirkung
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US6407074B1 (en) * 1997-06-11 2002-06-18 Pfizer Inc C-4″-substituted macrolide derivatives
HN1998000074A (es) 1997-06-11 1999-01-08 Pfizer Prod Inc Derivados de macrolidos c-4 sustituidos
EP0895999A1 (en) * 1997-08-06 1999-02-10 Pfizer Products Inc. C-4" substituted macrolide antibiotics
US6339063B1 (en) 1997-09-10 2002-01-15 Merck & Co., Inc. 9a-azalides as veterinary antimicrobial agents
SK285914B6 (sk) 1997-10-16 2007-11-02 Pliva, Farmaceutska Industrija, Dioni�Ko Dru�Tvo 3,6-Hemiketály, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie
EP0941998B1 (en) * 1998-03-03 2004-09-01 Pfizer Products Inc. 3,6-ketal macrolide antibiotics
TR200200434T2 (tr) 1998-11-03 2002-09-23 Pfizer Products Inc. Yeni makrolit antibiyotikler.
IL145739A0 (en) 1999-05-24 2002-07-25 Pfizer Prod Inc 13-methyl-erythromycin derivatives
EP1114826A3 (en) 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1122261A3 (en) 2000-01-31 2001-09-26 Pfizer Products Inc. 13 and 14-membered antibacterial macrolides
DE60104240T2 (de) 2000-06-30 2005-08-04 Pfizer Products Inc., Groton Makrolid-Antibiotika
EP1404693A2 (en) 2001-07-03 2004-04-07 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity

Also Published As

Publication number Publication date
EA200100396A1 (ru) 2001-10-22
AU5995299A (en) 2000-05-22
TR200101241T2 (tr) 2001-09-21
TNSN99205A1 (fr) 2005-11-10
HRP20010306A2 (en) 2002-06-30
NO20012155L (no) 2001-07-02
BR9914998A (pt) 2001-07-10
ID28286A (id) 2001-05-10
SK5812001A3 (en) 2001-12-03
WO2000026224A3 (en) 2000-11-16
OA11670A (en) 2005-01-12
CN1376160A (zh) 2002-10-23
CO5140110A1 (es) 2002-03-22
CA2349338C (en) 2005-12-06
HUP0104192A2 (hu) 2002-02-28
JP2002528553A (ja) 2002-09-03
US20030013665A1 (en) 2003-01-16
EE200100245A (et) 2002-10-15
IS5919A (is) 2001-04-17
CZ20011512A3 (cs) 2001-09-12
ZA200103289B (en) 2002-08-28
IL142628A0 (en) 2002-03-10
US20050004047A1 (en) 2005-01-06
US6835716B2 (en) 2004-12-28
US20020040007A1 (en) 2002-04-04
JP4043191B2 (ja) 2008-02-06
AP2001002131A0 (en) 2001-06-30
SV1999000188A (es) 2000-10-16
GT199900192A (es) 2001-04-26
EP1124837A2 (en) 2001-08-22
CA2349338A1 (en) 2000-05-11
KR20010083944A (ko) 2001-09-03
TR200200435T2 (tr) 2002-07-22
US7071170B2 (en) 2006-07-04
WO2000026224A2 (en) 2000-05-11
PE20001289A1 (es) 2000-11-22
NO20012155D0 (no) 2001-05-02
HK1049010A1 (zh) 2003-04-25
HUP0104192A3 (en) 2003-12-29
TR200200436T2 (tr) 2002-06-21
TR200200434T2 (tr) 2002-09-23
PA8485101A1 (es) 2002-08-26
BG105543A (en) 2001-12-29
MA26703A1 (fr) 2004-12-20
PL348114A1 (en) 2002-05-06

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Effective date: 20090520