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TR200200436T2 - Yeni makrolit antibiyotikler - Google Patents

Yeni makrolit antibiyotikler

Info

Publication number
TR200200436T2
TR200200436T2 TR2002/00436T TR200200436T TR200200436T2 TR 200200436 T2 TR200200436 T2 TR 200200436T2 TR 2002/00436 T TR2002/00436 T TR 2002/00436T TR 200200436 T TR200200436 T TR 200200436T TR 200200436 T2 TR200200436 T2 TR 200200436T2
Authority
TR
Turkey
Prior art keywords
formula
compounds
relates
infections
macrolide antibiotics
Prior art date
Application number
TR2002/00436T
Other languages
English (en)
Inventor
Kaneko Takushi
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of TR200200436T2 publication Critical patent/TR200200436T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Bu bulus, a,R1,R2,R3,R4,R5,R6 ve X'ten her birinin yukarida tanimlandigi gibi oldugu formül (I)'e ait bilesiklerle, ve bunlarin, çesitli bateriyel ve potozoal enfeksiyonlari ve bu enfeksiyonlara bagli bozukluklari tedavi etmek için kullanilabilen potanisyel antibakteriyel ve antiprotozoal maddeler olarak faydali farmasötik açidan kabul gören tuzlari ile ilgilidir. Bulus ayrica formül (I)'e ait bilesikleri ihtiva eden farmasötik kompozisyonlarla ve formül (I)'e ait bilesiklerin uygulanmasi suriyeti bateriyel ve protozoal enfeksiyonlarin tedavi edilmesine metotlarla da ilgilidir.
TR2002/00436T 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler TR200200436T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10683698P 1998-11-03 1998-11-03

Publications (1)

Publication Number Publication Date
TR200200436T2 true TR200200436T2 (tr) 2002-06-21

Family

ID=22313524

Family Applications (4)

Application Number Title Priority Date Filing Date
TR2002/00436T TR200200436T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler
TR2002/00434T TR200200434T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler.
TR2002/00435T TR200200435T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler.
TR2001/01241T TR200101241T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler

Family Applications After (3)

Application Number Title Priority Date Filing Date
TR2002/00434T TR200200434T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler.
TR2002/00435T TR200200435T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler.
TR2001/01241T TR200101241T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler

Country Status (34)

Country Link
US (3) US20020040007A1 (tr)
EP (1) EP1124837A2 (tr)
JP (1) JP4043191B2 (tr)
KR (1) KR20010083944A (tr)
CN (1) CN1376160A (tr)
AP (1) AP2001002131A0 (tr)
AU (1) AU5995299A (tr)
BG (1) BG105543A (tr)
BR (1) BR9914998A (tr)
CA (1) CA2349338C (tr)
CO (1) CO5140110A1 (tr)
CZ (1) CZ20011512A3 (tr)
EA (1) EA200100396A1 (tr)
EE (1) EE200100245A (tr)
GT (1) GT199900192A (tr)
HK (1) HK1049010A1 (tr)
HR (1) HRP20010306A2 (tr)
HU (1) HUP0104192A3 (tr)
ID (1) ID28286A (tr)
IL (1) IL142628A0 (tr)
IS (1) IS5919A (tr)
MA (1) MA26703A1 (tr)
NO (1) NO20012155L (tr)
OA (1) OA11670A (tr)
PA (1) PA8485101A1 (tr)
PE (1) PE20001289A1 (tr)
PL (1) PL348114A1 (tr)
SK (1) SK5812001A3 (tr)
SV (1) SV1999000188A (tr)
TN (1) TNSN99205A1 (tr)
TR (4) TR200200436T2 (tr)
UY (1) UY25780A1 (tr)
WO (1) WO2000026224A2 (tr)
ZA (1) ZA200103289B (tr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP9801420A0 (en) * 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
TR200200436T2 (tr) 1998-11-03 2002-06-21 Pfizer Inc. Yeni makrolit antibiyotikler
SI1147121T1 (en) 1999-01-27 2004-04-30 Pfizer Products Inc. Ketolide antibiotics
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
CN1373767A (zh) 1999-04-16 2002-10-09 奥索-麦克尼尔药品公司 酮式大环内酯抗菌剂
KR20020007374A (ko) 1999-04-16 2002-01-26 추후제출 매크롤라이드 항감염제
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
SK15162001A3 (sk) 1999-05-24 2003-02-04 Pfizer Products Inc. Deriváty 13-metylerytromycínu
EP1114826A3 (en) * 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
TR200401847T4 (tr) * 2000-06-30 2004-09-21 Pfizer Products Inc. Makrolit antibiyotikler.
RU2397987C2 (ru) * 2004-07-28 2010-08-27 Рэнбакси Лабораториз Лимитед Кетолидные производные в качестве антибактериальных агентов
EP1807439A2 (en) * 2004-10-25 2007-07-18 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
DE602005019786D1 (de) * 2004-12-21 2010-04-15 Pfizer Prod Inc Makrolide
EP1960413A2 (en) * 2005-11-23 2008-08-27 Ranbaxy Laboratories Limited Macrolides derivatives as antibacterial agents
US20090005325A1 (en) * 2005-11-23 2009-01-01 Biswajit Bas Ketolide Derivatives as Antibacterial Agents
US7801502B2 (en) * 2006-12-18 2010-09-21 Aai Corporation Method for implementing continuous radio frequency (RF) alignment in advanced electronic warfare (EW) signal stimulation systems
US8409628B2 (en) 2010-02-04 2013-04-02 Penguin IP Holdings, Inc. Methods and compositions for oxygenation of skin to treat skin disorders
US8900601B2 (en) 2010-03-31 2014-12-02 Jennifer Bartels Permeable mixtures, methods and compositions for the skin
AU2014262127B2 (en) * 2013-05-01 2019-05-02 Neoculi Pty Ltd Methods for treating bacterial infections
RU2537143C1 (ru) * 2013-11-08 2014-12-27 Государственное научное учреждение Ставропольский научно-исследовательский институт животноводства и кормопроизводства РАСХН Препарат для лечения и профилактики мастита у коров
WO2018080072A2 (ko) * 2016-10-27 2018-05-03 한국생명공학연구원 신규한 매크로라이드계 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 말라리아의 예방 또는 치료용 약학적 조성물

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TR200200436T2 (tr) 1998-11-03 2002-06-21 Pfizer Inc. Yeni makrolit antibiyotikler
SK15162001A3 (sk) 1999-05-24 2003-02-04 Pfizer Products Inc. Deriváty 13-metylerytromycínu
EP1114826A3 (en) 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1122261A3 (en) 2000-01-31 2001-09-26 Pfizer Products Inc. 13 and 14-membered antibacterial macrolides
TR200401847T4 (tr) 2000-06-30 2004-09-21 Pfizer Products Inc. Makrolit antibiyotikler.
CA2451391A1 (en) 2001-07-03 2003-01-16 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity

Also Published As

Publication number Publication date
SK5812001A3 (en) 2001-12-03
EA200100396A1 (ru) 2001-10-22
US20020040007A1 (en) 2002-04-04
TNSN99205A1 (fr) 2005-11-10
JP2002528553A (ja) 2002-09-03
HRP20010306A2 (en) 2002-06-30
PL348114A1 (en) 2002-05-06
EP1124837A2 (en) 2001-08-22
TR200200434T2 (tr) 2002-09-23
US7071170B2 (en) 2006-07-04
BR9914998A (pt) 2001-07-10
AP2001002131A0 (en) 2001-06-30
TR200200435T2 (tr) 2002-07-22
HUP0104192A2 (hu) 2002-02-28
UY25780A1 (es) 2001-08-27
PE20001289A1 (es) 2000-11-22
OA11670A (en) 2005-01-12
MA26703A1 (fr) 2004-12-20
US20050004047A1 (en) 2005-01-06
ID28286A (id) 2001-05-10
TR200101241T2 (tr) 2001-09-21
US6835716B2 (en) 2004-12-28
KR20010083944A (ko) 2001-09-03
CA2349338C (en) 2005-12-06
IL142628A0 (en) 2002-03-10
NO20012155D0 (no) 2001-05-02
WO2000026224A3 (en) 2000-11-16
WO2000026224A2 (en) 2000-05-11
SV1999000188A (es) 2000-10-16
BG105543A (en) 2001-12-29
CZ20011512A3 (cs) 2001-09-12
HUP0104192A3 (en) 2003-12-29
HK1049010A1 (zh) 2003-04-25
PA8485101A1 (es) 2002-08-26
CO5140110A1 (es) 2002-03-22
JP4043191B2 (ja) 2008-02-06
GT199900192A (es) 2001-04-26
ZA200103289B (en) 2002-08-28
NO20012155L (no) 2001-07-02
CA2349338A1 (en) 2000-05-11
CN1376160A (zh) 2002-10-23
US20030013665A1 (en) 2003-01-16
IS5919A (is) 2001-04-17
AU5995299A (en) 2000-05-22
EE200100245A (et) 2002-10-15

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