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UA94455C2 - Oxadiazolidinedione compound - Google Patents

Oxadiazolidinedione compound

Info

Publication number
UA94455C2
UA94455C2 UAA200813478A UAA200813478A UA94455C2 UA 94455 C2 UA94455 C2 UA 94455C2 UA A200813478 A UAA200813478 A UA A200813478A UA A200813478 A UAA200813478 A UA A200813478A UA 94455 C2 UA94455 C2 UA 94455C2
Authority
UA
Ukraine
Prior art keywords
compound
insulin secretion
oxadiazolidinedione
oxadiazolidinedione compound
effect
Prior art date
Application number
UAA200813478A
Other languages
English (en)
Ukrainian (uk)
Inventor
Кендзи Негора
Фумийоси Ивасаки
Кей Охнуки
Тосио Куросаки
Ясухиро ЙОНЕТОКУ
Норио Асаи
Сигера Йосида
Такатоса Сога
Original Assignee
Астеллас Фарма Инк
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Астеллас Фарма Инк filed Critical Астеллас Фарма Инк
Publication of UA94455C2 publication Critical patent/UA94455C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Изобретение касается соединения формулы (I)или ее фармацевтически приемлемой соли, которая имеет агонистическое действие по отношению к GPR40 и может быть применена для стимуляции секреции инсулина или для профилактики/лечения заболеваний, которые связаны с GPR40, таких как диабет и т.п., а также фармацевтической композиции на ее основе.
UAA200813478A 2006-04-24 2007-04-23 Oxadiazolidinedione compound UA94455C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2006118630 2006-04-24

Publications (1)

Publication Number Publication Date
UA94455C2 true UA94455C2 (en) 2011-05-10

Family

ID=38625122

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200813478A UA94455C2 (en) 2006-04-24 2007-04-23 Oxadiazolidinedione compound

Country Status (17)

Country Link
US (1) US7968552B2 (ru)
EP (1) EP2011788A4 (ru)
JP (1) JP5309991B2 (ru)
KR (1) KR20090005208A (ru)
CN (1) CN101426775B (ru)
AR (1) AR060628A1 (ru)
AU (1) AU2007241759B2 (ru)
BR (1) BRPI0710531A2 (ru)
CA (1) CA2650124A1 (ru)
MX (1) MX2008013660A (ru)
NO (1) NO20084919L (ru)
NZ (1) NZ572146A (ru)
RU (1) RU2440994C2 (ru)
TW (1) TW200815377A (ru)
UA (1) UA94455C2 (ru)
WO (1) WO2007123225A1 (ru)
ZA (1) ZA200808639B (ru)

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Also Published As

Publication number Publication date
CN101426775B (zh) 2012-10-31
AU2007241759B2 (en) 2012-05-17
AU2007241759A1 (en) 2007-11-01
CA2650124A1 (en) 2007-11-01
EP2011788A1 (en) 2009-01-07
NZ572146A (en) 2010-09-30
ZA200808639B (en) 2009-12-30
WO2007123225A1 (ja) 2007-11-01
JPWO2007123225A1 (ja) 2009-09-10
US20090186909A1 (en) 2009-07-23
MX2008013660A (es) 2008-11-10
TW200815377A (en) 2008-04-01
EP2011788A4 (en) 2010-10-13
BRPI0710531A2 (pt) 2012-06-19
KR20090005208A (ko) 2009-01-12
US7968552B2 (en) 2011-06-28
CN101426775A (zh) 2009-05-06
RU2008146088A (ru) 2010-05-27
RU2440994C2 (ru) 2012-01-27
NO20084919L (no) 2009-01-20
JP5309991B2 (ja) 2013-10-09
AR060628A1 (es) 2008-07-02

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