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UA81499C2 - Pharmaceutical composition containing histone deacetylase inhibitor - Google Patents

Pharmaceutical composition containing histone deacetylase inhibitor

Info

Publication number
UA81499C2
UA81499C2 UAA200512454A UAA200512454A UA81499C2 UA 81499 C2 UA81499 C2 UA 81499C2 UA A200512454 A UAA200512454 A UA A200512454A UA A200512454 A UAA200512454 A UA A200512454A UA 81499 C2 UA81499 C2 UA 81499C2
Authority
UA
Ukraine
Prior art keywords
pharmaceutical composition
composition containing
histone deacetylase
deacetylase inhibitor
containing histone
Prior art date
Application number
UAA200512454A
Other languages
English (en)
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of UA81499C2 publication Critical patent/UA81499C2/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
UAA200512454A 2003-05-26 2004-05-26 Pharmaceutical composition containing histone deacetylase inhibitor UA81499C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003148073 2003-05-26
PCT/JP2004/007562 WO2004103369A1 (fr) 2003-05-26 2004-05-26 Composition pharmaceutique contenant un inhibiteur d'histone deacetylase

Publications (1)

Publication Number Publication Date
UA81499C2 true UA81499C2 (en) 2008-01-10

Family

ID=33475383

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200512454A UA81499C2 (en) 2003-05-26 2004-05-26 Pharmaceutical composition containing histone deacetylase inhibitor

Country Status (27)

Country Link
US (1) US20070098816A1 (fr)
EP (1) EP1626719A1 (fr)
JP (1) JP2006526031A (fr)
KR (1) KR100938712B1 (fr)
CN (2) CN101322707A (fr)
AR (1) AR045318A1 (fr)
AU (1) AU2004241873C1 (fr)
BR (1) BRPI0410959A (fr)
CA (4) CA2634765A1 (fr)
CL (1) CL2004001278A1 (fr)
CO (1) CO5660262A2 (fr)
CR (1) CR8163A (fr)
CU (1) CU23490B7 (fr)
EC (1) ECSP056253A (fr)
IL (1) IL171941A0 (fr)
ME (1) MEP32308A (fr)
MX (1) MXPA05012345A (fr)
NO (1) NO20055417L (fr)
NZ (1) NZ543591A (fr)
PE (1) PE20050206A1 (fr)
RS (1) RS20050884A (fr)
RU (1) RU2322971C2 (fr)
TW (1) TW200505424A (fr)
UA (1) UA81499C2 (fr)
UY (1) UY28330A1 (fr)
WO (1) WO2004103369A1 (fr)
ZA (1) ZA200509515B (fr)

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US7244853B2 (en) 2001-05-09 2007-07-17 President And Fellows Of Harvard College Dioxanes and uses thereof
US7154002B1 (en) 2002-10-08 2006-12-26 Takeda San Diego, Inc. Histone deacetylase inhibitors
CA2518318A1 (fr) 2003-03-17 2004-09-30 Takeda San Diego, Inc. Inhibiteurs d'histone deacetylase
MXPA06003222A (es) * 2003-09-25 2006-05-22 Astellas Pharma Inc Agente antitumoral que comprende un inhibidor de histona desacetilasa y un inhibidor de topoisomerasa ii.
US7446126B2 (en) * 2004-10-08 2008-11-04 Indena S.P.A. Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
EP1712552A1 (fr) * 2005-04-11 2006-10-18 INDENA S.p.A. Semisynthese de preparation de 10-deacetyl-n-debenzoyl paclitaxel
EP1824831A2 (fr) 2004-12-16 2007-08-29 Takeda San Diego, Inc. Inhibiteurs d'histone desacetylase
WO2006099396A2 (fr) * 2005-03-11 2006-09-21 The Regents Of The University Of Colorado Inhibiteurs d'histone deacetylase permettant de sensibiliser des cellules cancereuses aux inhibiteurs du facteur de croissance epidermique
CA2601706C (fr) 2005-03-22 2016-09-20 Dana-Farber Cancer Institute, Inc. Traitement de troubles lies a la degradation de proteines
JP2008540574A (ja) 2005-05-11 2008-11-20 タケダ サン ディエゴ インコーポレイテッド ヒストンデアセチラーゼ阻害剤
CN101263121A (zh) 2005-07-14 2008-09-10 塔克达圣地亚哥公司 组蛋白脱乙酰基酶抑制剂
EP1991247B1 (fr) 2006-02-14 2015-10-14 President and Fellows of Harvard College Inhibiteurs bifonctionnels d'histone déacétylase
JP5409015B2 (ja) * 2006-02-14 2014-02-05 プレジデント アンド フェロウズ オブ ハーバード カレッジ ヒストンデアセチラーゼ阻害剤
AU2007248656B2 (en) 2006-05-03 2013-04-04 Dana-Farber Cancer Institute, Inc. Histone deacetylase and tubulin deacetylase inhibitors
GB0625283D0 (en) * 2006-12-19 2007-01-24 Cyclacel Ltd Combination
US9408816B2 (en) 2006-12-26 2016-08-09 Pharmacyclics Llc Method of using histone deacetylase inhibitors and monitoring biomarkers in combination therapy
US20090131367A1 (en) * 2007-11-19 2009-05-21 The Regents Of The University Of Colorado Combinations of HDAC Inhibitors and Proteasome Inhibitors
AU2008338631A1 (en) * 2007-12-14 2009-06-25 Georgetown University Histone deacetylase inhibitors
EP2321264B1 (fr) 2008-07-23 2016-05-04 President and Fellows of Harvard College Inhibiteurs de désacétylase et leurs utilisations
GB2462893B (en) * 2008-08-29 2010-10-13 Bayer Schering Pharma Ag N-(2-aminophenyl)-4-[N-(pyridine-3-yl)-methoxycarbonyl-aminomethyl]-benzamide (MS-275) polymorph B
HRP20120183T8 (en) * 2008-08-29 2012-11-30 Bayer Pharma Aktiengesellschaft N-(2-aminophenyl)-4-[n-(pyridine-3-yl)-methoxycarbonyl-aminomethyl]-benzamide (ms-275)polymorph b
AU2009327357C1 (en) 2008-12-19 2017-02-02 Vertex Pharmaceuticals Incorporated Pyrazine derivatives useful as inhibitors of ATR kinase
US20120034302A1 (en) * 2009-02-11 2012-02-09 Liangping Yu Particulate composition and the method of making the same
JP2012525371A (ja) * 2009-05-01 2012-10-22 オンコザイム・ファーマ・インコーポレイテッド 癌を治療するためのペンタミジンの組み合わせ
EP2440519A1 (fr) * 2009-06-08 2012-04-18 Gilead Sciences, Inc. Composés inhibiteurs d'hdac à base d'alkanoylamino benzamide aniline
WO2011019393A2 (fr) 2009-08-11 2011-02-17 President And Fellows Of Harvard College Inhibiteurs de hdac classe- et isoforme-spécifiques et utilisations de ceux-ci
SG178873A1 (en) * 2009-08-25 2012-04-27 Abraxis Bioscience Llc Combination therapy with nanoparticle compositions of taxane and hedgehog inhibitors
MX2012013081A (es) 2010-05-12 2013-05-09 Vertex Pharma Compuestos utiles como inhibidores de cinasa atr.
KR101892788B1 (ko) 2011-09-13 2018-08-28 파마싸이클릭스 엘엘씨 벤다무스틴과 조합된 히스톤 디아세틸라제 억제제의 제제 및 그의 용도
SG11201401095YA (en) * 2011-09-30 2014-04-28 Vertex Pharma Treating pancreatic cancer and non-small cell lung cancer with atr inhibitors
RS59337B1 (sr) 2011-09-30 2019-10-31 Vertex Pharma Postupak za izradu jedinjenja, korisnih kao inhibitori atr kinaze
WO2013085902A1 (fr) * 2011-12-05 2013-06-13 The University Of Texas M.D. Procédés de polythérapie pour le traitement d'un cancer du sein inflammatoire
ES2654670T3 (es) 2012-04-05 2018-02-14 Vertex Pharmaceuticals Incorporated Compuestos útiles como inhibidores de la cinasa ATR y terapias de combinación de los mismos
WO2014055756A1 (fr) 2012-10-04 2014-04-10 Vertex Pharmaceuticals Incorporated Procédé pour la mesure d'augmentations de lésions d'adn à médiation par l'inhibition d'atr
WO2014164708A1 (fr) 2013-03-12 2014-10-09 Quanticel Pharmaceuticals, Inc. Inhibiteurs d'histone déméthylase
WO2014141129A2 (fr) * 2013-03-14 2014-09-18 Grueneberg Dorre A Nouveaux procédés, composés et compositions pour l'inhibition de ros
WO2015127227A1 (fr) * 2014-02-21 2015-08-27 Cleveland Biolabs, Inc. Utilisations de flagelline pour améliorer la chimiothérapie
JP6723663B2 (ja) 2014-09-17 2020-07-15 セルジーン クオンティセル リサーチ，インク． ヒストンデメチラーゼ阻害剤
AU2016331955B2 (en) 2015-09-30 2022-07-21 Vertex Pharmaceuticals Incorporated Method for treating cancer using a combination of DNA damaging agents and ATR inhibitors
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
US11596612B1 (en) 2022-03-08 2023-03-07 PTC Innovations, LLC Topical anesthetics
WO2025041160A1 (fr) * 2023-08-19 2025-02-27 Birla Institute Of Technology And Science (Bits), Pilani Molécules conjuguées bifonctionnelles pour le traitement du cancer et leur procédé de fabrication

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FR2697752B1 (fr) * 1992-11-10 1995-04-14 Rhone Poulenc Rorer Sa Compositions antitumorales contenant des dérivés du taxane.
JP3354090B2 (ja) 1996-09-30 2002-12-09 シエーリング アクチエンゲゼルシャフト 分化誘導剤
US6174905B1 (en) * 1996-09-30 2001-01-16 Mitsui Chemicals, Inc. Cell differentiation inducer
US6794392B1 (en) * 1996-09-30 2004-09-21 Schering Aktiengesellschaft Cell differentiation inducer
US5753637A (en) * 1996-10-09 1998-05-19 Ideal Ideas, Inc. Method of treating acne conditions
WO2000018393A1 (fr) * 1998-09-25 2000-04-06 Warner-Lambert Company Chimiotherapie contre le cancer, dans laquelle de l'acetyldinaline combinee a de la gemcitabine, de la capecitabine ou du cisplatine sont utilises
AU4144400A (en) * 1999-04-27 2000-11-10 Mitsubishi Pharma Corporation Preventives/remedies for liver diseases
KR20020060226A (ko) * 1999-11-10 2002-07-16 로즈 암스트롱, 크리스틴 에이. 트러트웨인 배합 화학요법
US6905669B2 (en) * 2001-04-24 2005-06-14 Supergen, Inc. Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
CZ20022216A3 (cs) * 2001-07-02 2003-05-14 Warner-Lambert Company Kombinační chemoterapie
JP2003137866A (ja) * 2001-11-01 2003-05-14 Sankyo Co Ltd フェニレンジアミン誘導体

Also Published As

Publication number Publication date
RU2005140570A (ru) 2006-06-10
IL171941A0 (en) 2006-04-10
BRPI0410959A (pt) 2006-07-04
CO5660262A2 (es) 2006-07-31
MEP32308A (en) 2010-10-10
TW200505424A (en) 2005-02-16
CA2634765A1 (fr) 2004-12-02
CA2634766A1 (fr) 2004-12-02
CN1794991A (zh) 2006-06-28
AU2004241873B2 (en) 2008-05-08
US20070098816A1 (en) 2007-05-03
WO2004103369A1 (fr) 2004-12-02
ZA200509515B (en) 2006-07-26
UY28330A1 (es) 2004-12-31
EP1626719A1 (fr) 2006-02-22
CA2634709A1 (fr) 2004-12-02
RU2322971C2 (ru) 2008-04-27
PE20050206A1 (es) 2005-03-26
NO20055417L (no) 2005-12-19
CU23490B7 (es) 2010-02-23
JP2006526031A (ja) 2006-11-16
AU2004241873A1 (en) 2004-12-02
NO20055417D0 (no) 2005-11-16
ECSP056253A (es) 2006-10-25
CL2004001278A1 (es) 2005-05-06
AU2004241873B8 (en) 2008-05-29
CN101322707A (zh) 2008-12-17
RS20050884A (sr) 2008-04-04
CR8163A (es) 2006-07-14
CA2527191A1 (fr) 2004-12-02
KR20060009371A (ko) 2006-01-31
MXPA05012345A (es) 2006-02-08
AR045318A1 (es) 2005-10-26
AU2004241873C1 (en) 2009-01-22
KR100938712B1 (ko) 2010-01-25
NZ543591A (en) 2009-09-25

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