UA81499C2 - Pharmaceutical composition containing histone deacetylase inhibitor - Google Patents

Pharmaceutical composition containing histone deacetylase inhibitor

Info

Publication number: UA81499C2
Authority: UA; Ukraine
Prior art keywords: pharmaceutical composition; composition containing; histone deacetylase; deacetylase inhibitor; containing histone
Prior art date: 2003-05-26

Application number

UAA200512454A

Other languages

English (en)

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-05-26

Filing date

2004-05-26

Publication date

2008-01-10

2004-05-26 Application filed by Schering Ag filed Critical Schering Ag

2008-01-10 Publication of UA81499C2 publication Critical patent/UA81499C2/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pyridine Compounds (AREA)

UAA200512454A 2003-05-26 2004-05-26 Pharmaceutical composition containing histone deacetylase inhibitor UA81499C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2003148073		2003-05-26
PCT/JP2004/007562 WO2004103369A1 (en)	2003-05-26	2004-05-26	Pharmaceutical composition containing histone deacetylase inhibitor

Publications (1)

Publication Number	Publication Date
UA81499C2 true UA81499C2 (en)	2008-01-10

Family

ID=33475383

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UAA200512454A UA81499C2 (en)	2003-05-26	2004-05-26	Pharmaceutical composition containing histone deacetylase inhibitor

Country Status (27)

Country	Link
US (1)	US20070098816A1 (xx)
EP (1)	EP1626719A1 (xx)
JP (1)	JP2006526031A (xx)
KR (1)	KR100938712B1 (xx)
CN (2)	CN1794991A (xx)
AR (1)	AR045318A1 (xx)
AU (1)	AU2004241873C1 (xx)
BR (1)	BRPI0410959A (xx)
CA (4)	CA2634709A1 (xx)
CL (1)	CL2004001278A1 (xx)
CO (1)	CO5660262A2 (xx)
CR (1)	CR8163A (xx)
CU (1)	CU23490B7 (xx)
EC (1)	ECSP056253A (xx)
IL (1)	IL171941A0 (xx)
ME (1)	MEP32308A (xx)
MX (1)	MXPA05012345A (xx)
NO (1)	NO20055417L (xx)
NZ (1)	NZ543591A (xx)
PE (1)	PE20050206A1 (xx)
RS (1)	RS20050884A (xx)
RU (1)	RU2322971C2 (xx)
TW (1)	TW200505424A (xx)
UA (1)	UA81499C2 (xx)
UY (1)	UY28330A1 (xx)
WO (1)	WO2004103369A1 (xx)
ZA (1)	ZA200509515B (xx)

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US7446126B2 (en) *	2004-10-08	2008-11-04	Indena S.P.A.	Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
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MX2007011148A (es) *	2005-03-11	2008-02-22	Univ Colorado	Inhibidores de histona desacetilasa que sensibilizan celulas cancerosas respecto a los inhibidores de factor de crecimiento.
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JP2008540574A (ja)	2005-05-11	2008-11-20	タケダサンディエゴインコーポレイテッド	ヒストンデアセチラーゼ阻害剤
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US8383855B2 (en)	2006-02-14	2013-02-26	President And Fellows Of Harvard College	Histone deacetylase inhibitors
JP5441416B2 (ja)	2006-02-14	2014-03-12	プレジデントアンドフェロウズオブハーバードカレッジ	二官能性ヒストンデアセチラーゼインヒビター
CA2654540C (en)	2006-05-03	2017-01-17	President And Fellows Of Harvard College	Histone deacetylase and tubulin deacetylase inhibitors
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US20090131367A1 (en) *	2007-11-19	2009-05-21	The Regents Of The University Of Colorado	Combinations of HDAC Inhibitors and Proteasome Inhibitors
WO2009079375A1 (en) *	2007-12-14	2009-06-25	Georgetown University	Histone deacetylase inhibitors
KR101708946B1 (ko)	2008-07-23	2017-02-21	다나-파버 캔서 인스티튜트 인크.	탈아세틸화제 억제제 및 그것의 용도
GB2462893B (en) *	2008-08-29	2010-10-13	Bayer Schering Pharma Ag	N-(2-aminophenyl)-4-[N-(pyridine-3-yl)-methoxycarbonyl-aminomethyl]-benzamide (MS-275) polymorph B
BRPI0918580B8 (pt) *	2008-08-29	2021-05-25	Bayer Ip Gmbh	polimorfo cristalino b da n-(2-aminofenil)-4-[n-(piridina3-il)metóxi-carbonilaminometil]-benzamida, composição e combinação contendo o mesmo, uso e seu processo de produção
EP2376485B1 (en)	2008-12-19	2017-12-06	Vertex Pharmaceuticals Incorporated	Pyrazine derivatives useful as inhibitors of atr kinase
WO2010093561A1 (en) *	2009-02-11	2010-08-19	Liangping Yu	Particulate composition and the method of making the same
CN102573826A (zh) *	2009-05-01	2012-07-11	奥克兹美制药公司	用于治疗癌症的喷他脒组合
EP2440519A1 (en) *	2009-06-08	2012-04-18	Gilead Sciences, Inc.	Alkanoylamino benzamide aniline hdac inihibitor compounds
WO2011019393A2 (en)	2009-08-11	2011-02-17	President And Fellows Of Harvard College	Class- and isoform-specific hdac inhibitors and uses thereof
KR20120053052A (ko) *	2009-08-25	2012-05-24	아브락시스 바이오사이언스, 엘엘씨	헤지호그 억제제 및 탁산의 나노입자 조성물로의 조합 요법
KR20130066633A (ko)	2010-05-12	2013-06-20	버텍스 파마슈티칼스 인코포레이티드	Ａｔｒ 키나제의 억제제로서 유용한 화합물
SG2014014419A (en)	2011-09-13	2014-07-30	Pharmacyclics Inc	Formulations of histone deacetylase inhibitor in combination with bendamustine and uses thereof
BR112014007690B1 (pt) *	2011-09-30	2022-10-04	Vertex Pharmaceuticals Incorporated	Usos de inibidores de atr no tratamento de câncer pancreático e câncer de pulmão de células não pequenas
CN103987709B (zh)	2011-09-30	2016-09-28	沃泰克斯药物股份有限公司	用于制备可用作atr激酶抑制剂的化合物的方法
WO2013085902A1 (en) *	2011-12-05	2013-06-13	The University Of Texas M.D.	Combination therapy methods for treating an inflammatory breast cancer
EP3311816A1 (en)	2012-04-05	2018-04-25	Vertex Pharmaceuticals Incorporated	Compounds useful as inhibitors of atr kinase for the treatment of cancer
US8999632B2 (en)	2012-10-04	2015-04-07	Vertex Pharmaceuticals Incorporated	Method for measuring ATR inhibition mediated increases in DNA damage
EP2968282B1 (en)	2013-03-12	2018-05-09	Celgene Quanticel Research, Inc.	Histone dementhylase inhibitors
US9963452B2 (en) *	2013-03-14	2018-05-08	Augusta Pharmaceuticals Inc.	Methods, compounds, and compositions for inhibition of ROS
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US9758517B2 (en)	2014-09-17	2017-09-12	Celgene Quanticel Research, Inc.	Histone demethylase inhibitors
RU2768621C1 (ru)	2015-09-30	2022-03-24	Вертекс Фармасьютикалз Инкорпорейтед	Способ лечения рака с использованием комбинации повреждающих днк средств и ингибиторов atr
TWI794171B (zh)	2016-05-11	2023-03-01	美商滬亞生物國際有限公司	Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
TWI808055B (zh)	2016-05-11	2023-07-11	美商滬亞生物國際有限公司	Hdac 抑制劑與 pd-1 抑制劑之組合治療
US11596612B1 (en)	2022-03-08	2023-03-07	PTC Innovations, LLC	Topical anesthetics
WO2025041160A1 (en) *	2023-08-19	2025-02-27	Birla Institute Of Technology And Science (Bits), Pilani	Bifunctional conjugate molecules for cancer treatment and process of making the same

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FR2697752B1 (fr) *	1992-11-10	1995-04-14	Rhone Poulenc Rorer Sa	Compositions antitumorales contenant des dérivés du taxane.
US6174905B1 (en) *	1996-09-30	2001-01-16	Mitsui Chemicals, Inc.	Cell differentiation inducer
US6794392B1 (en) *	1996-09-30	2004-09-21	Schering Aktiengesellschaft	Cell differentiation inducer
JP3354090B2 (ja) *	1996-09-30	2002-12-09	シエーリングアクチエンゲゼルシャフト	分化誘導剤
US5753637A (en) *	1996-10-09	1998-05-19	Ideal Ideas, Inc.	Method of treating acne conditions
AU762079B2 (en) *	1998-09-25	2003-06-19	Warner-Lambert Company	Chemotherapy of cancer with acetyldinaline in combination with gemcitabine, capecitabine or cisplatin
DE60045890D1 (de) *	1999-04-27	2011-06-09	Mitsubishi Tanabe Pharma Corp	Arzneimittel zur präventiven oder therapeutische Behandlung von Lebererkrankungen
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CZ20022216A3 (cs) *	2001-07-02	2003-05-14	Warner-Lambert Company	Kombinační chemoterapie
JP2003137866A (ja) *	2001-11-01	2003-05-14	Sankyo Co Ltd	フェニレンジアミン誘導体

2004
- 2004-05-25 PE PE2004000533A patent/PE20050206A1/es not_active Application Discontinuation
- 2004-05-26 CA CA002634709A patent/CA2634709A1/en not_active Abandoned
- 2004-05-26 CN CNA2004800146332A patent/CN1794991A/zh active Pending
- 2004-05-26 WO PCT/JP2004/007562 patent/WO2004103369A1/en not_active Ceased
- 2004-05-26 JP JP2006519178A patent/JP2006526031A/ja active Pending
- 2004-05-26 US US10/558,208 patent/US20070098816A1/en not_active Abandoned
- 2004-05-26 BR BRPI0410959-7A patent/BRPI0410959A/pt not_active IP Right Cessation
- 2004-05-26 EP EP04734923A patent/EP1626719A1/en not_active Withdrawn
- 2004-05-26 RU RU2005140570/15A patent/RU2322971C2/ru active IP Right Revival
- 2004-05-26 ME MEP-323/08A patent/MEP32308A/xx unknown
- 2004-05-26 UA UAA200512454A patent/UA81499C2/xx unknown
- 2004-05-26 UY UY28330A patent/UY28330A1/es not_active Application Discontinuation
- 2004-05-26 NZ NZ543591A patent/NZ543591A/en unknown
- 2004-05-26 CL CL200401278A patent/CL2004001278A1/es unknown
- 2004-05-26 RS YUP-2005/0884A patent/RS20050884A/sr unknown
- 2004-05-26 CN CNA2008101007303A patent/CN101322707A/zh active Pending
- 2004-05-26 CA CA002527191A patent/CA2527191A1/en not_active Abandoned
- 2004-05-26 AR ARP040101807A patent/AR045318A1/es not_active Application Discontinuation
- 2004-05-26 MX MXPA05012345A patent/MXPA05012345A/es active IP Right Grant
- 2004-05-26 CA CA002634765A patent/CA2634765A1/en not_active Abandoned
- 2004-05-26 AU AU2004241873A patent/AU2004241873C1/en not_active Ceased
- 2004-05-26 KR KR1020057022615A patent/KR100938712B1/ko not_active Expired - Fee Related
- 2004-05-26 CA CA002634766A patent/CA2634766A1/en not_active Abandoned
- 2004-05-26 TW TW093114934A patent/TW200505424A/zh unknown
2005
- 2005-11-14 IL IL171941A patent/IL171941A0/en unknown
- 2005-11-16 NO NO20055417A patent/NO20055417L/no not_active Application Discontinuation
- 2005-11-24 ZA ZA200509515A patent/ZA200509515B/en unknown
- 2005-11-25 CU CU20050237A patent/CU23490B7/es not_active IP Right Cessation
- 2005-12-22 CO CO05129159A patent/CO5660262A2/es unknown
- 2005-12-26 EC EC2005006253A patent/ECSP056253A/es unknown
2006
- 2006-01-02 CR CR8163A patent/CR8163A/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
MEP32308A (en)	2010-10-10
KR100938712B1 (ko)	2010-01-25
EP1626719A1 (en)	2006-02-22
ECSP056253A (es)	2006-10-25
AU2004241873B8 (en)	2008-05-29
RU2005140570A (ru)	2006-06-10
CN1794991A (zh)	2006-06-28
IL171941A0 (en)	2006-04-10
NO20055417L (no)	2005-12-19
ZA200509515B (en)	2006-07-26
RU2322971C2 (ru)	2008-04-27
JP2006526031A (ja)	2006-11-16
US20070098816A1 (en)	2007-05-03
AU2004241873C1 (en)	2009-01-22
CL2004001278A1 (es)	2005-05-06
RS20050884A (sr)	2008-04-04
AU2004241873B2 (en)	2008-05-08
NZ543591A (en)	2009-09-25
MXPA05012345A (es)	2006-02-08
BRPI0410959A (pt)	2006-07-04
CA2634765A1 (en)	2004-12-02
CU23490B7 (es)	2010-02-23
PE20050206A1 (es)	2005-03-26
AU2004241873A1 (en)	2004-12-02
CA2634709A1 (en)	2004-12-02
UY28330A1 (es)	2004-12-31
TW200505424A (en)	2005-02-16
NO20055417D0 (no)	2005-11-16
KR20060009371A (ko)	2006-01-31
CO5660262A2 (es)	2006-07-31
CN101322707A (zh)	2008-12-17
WO2004103369A1 (en)	2004-12-02
CA2527191A1 (en)	2004-12-02
CA2634766A1 (en)	2004-12-02
AR045318A1 (es)	2005-10-26
CR8163A (es)	2006-07-14

Publication	Publication Date	Title
TW200505424A (en)	2005-02-16	Pharmaceutical composition containing histone deacetylase inhibitor
NO20055216L (no)	2005-12-08	Nye hydroksamater som terapeutiske midler
MXPA04008797A (es)	2004-11-26	Inhibidores de histona desacetilasa.
PL371100A1 (en)	2005-06-13	Sulfonylamino-derivatives as novel inhibitors of histone deacetylase
PL370982A1 (en)	2005-06-13	Carbonylamino-derivatives as novel inhibitors of histone deacetylase
PL371036A1 (en)	2005-06-13	Piperazinyl-, piperidinyl- and morpholinyl-derivatives as novel inhibitors of histone deacetylase
MXPA06000013A (es)	2006-03-21	Agente terapeutico para sarcoma de tejido suave.
EA200801492A1 (ru)	2008-10-30	Фармацевтическое применение замещенных амидов
MY142177A (en)	2010-10-15	Benzamide derivatives useful as histone deacetylase inhibitors
NO20033732L (no)	2003-10-22	N-substituerte ikke-aryl-heterosykliske NMDA/NR2B-antagonister, og farmasoytiske preparater som omfatter slike forbindelser.
PL370990A1 (en)	2005-06-13	Sulfonyl-derivatives as novel inhibitors of histone deacetylase
WO2008101907A3 (en)	2008-10-23	N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase
PL1656348T4 (pl)	2007-07-31	Pochodne acetylenu jako inhibitory deacetylazy histonowej
ZA200708749B (en)	2009-08-26	Hydroxamates as histone deacetylase inhibitors and pharmaceutical formulations containing them
EA200700143A1 (ru)	2007-06-29	Производные замещенного пропенилпиперазина в качестве новых ингибиторов гистондеацетилазы
GB2427405A (en)	2006-12-27	Novel hydroxamates as therapeutic agents
WO2006063294A3 (en)	2006-09-21	Novel inhibitors of histone deacetylase for the treatment of disease
MXPA02010828A (es)	2004-07-16	Composicion farmaceutica en capsulas que comprende un antiinflamatorio no esteroideo y un analgesico opiaceo para el manejo del dolor.
TW200638927A (en)	2006-11-16	Bambuterol and integrin inhibitor combination
PA8633001A1 (es)	2006-12-07	Composicion farmaceutica antimicobacterial
MX2008008470A (es)	2008-09-26	Nuevos derivados pirrolicos con actividad inhibidora de desacetilasa de histonas.
ATE402703T1 (de)	2008-08-15	Tablette enthaltend efletirizin und pseudoephedrin
TW200640464A (en)	2006-12-01	Pharmaceutical composition comprising phenoxazinium compounds as an active ingredient
TH81162A (th)	2006-11-16	สารผสมทางเภสัชกรรมที่มีตัวยับยั้งฮิสโตนดีอะซีทิลเลส
TH81162B (th)	2006-11-16	สารผสมทางเภสัชกรรมที่มีตัวยับยั้งฮิสโตนดีอะซีทิลเลส