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NO20055417L - Farmasoytisk blanding inneholdene histon-deacetylaseinhibitor - Google Patents

Farmasoytisk blanding inneholdene histon-deacetylaseinhibitor

Info

Publication number
NO20055417L
NO20055417L NO20055417A NO20055417A NO20055417L NO 20055417 L NO20055417 L NO 20055417L NO 20055417 A NO20055417 A NO 20055417A NO 20055417 A NO20055417 A NO 20055417A NO 20055417 L NO20055417 L NO 20055417L
Authority
NO
Norway
Prior art keywords
pharmaceutical composition
composition containing
histone deacetylase
deacetylase inhibitor
containing histone
Prior art date
Application number
NO20055417A
Other languages
English (en)
Other versions
NO20055417D0 (no
Inventor
Osamu Nakanishi
Tatsuo Sugawara
Hideyuki Migita
Yasuhiro Matsuba
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO20055417D0 publication Critical patent/NO20055417D0/no
Publication of NO20055417L publication Critical patent/NO20055417L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Et anticancer-medikament som har en synergistisk effekt ved kombinert anvendelse av et histon-acetylase-derivat så som N-(2-aminofenyl)-4-[N-(pyridinylmetoksykarbonyl)aminometyl]benzamid (MS-275) og en annen anticancer-aktiv substans.
NO20055417A 2003-05-26 2005-11-16 Farmasoytisk blanding inneholdene histon-deacetylaseinhibitor NO20055417L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003148073 2003-05-26
PCT/JP2004/007562 WO2004103369A1 (en) 2003-05-26 2004-05-26 Pharmaceutical composition containing histone deacetylase inhibitor

Publications (2)

Publication Number Publication Date
NO20055417D0 NO20055417D0 (no) 2005-11-16
NO20055417L true NO20055417L (no) 2005-12-19

Family

ID=33475383

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055417A NO20055417L (no) 2003-05-26 2005-11-16 Farmasoytisk blanding inneholdene histon-deacetylaseinhibitor

Country Status (27)

Country Link
US (1) US20070098816A1 (no)
EP (1) EP1626719A1 (no)
JP (1) JP2006526031A (no)
KR (1) KR100938712B1 (no)
CN (2) CN101322707A (no)
AR (1) AR045318A1 (no)
AU (1) AU2004241873C1 (no)
BR (1) BRPI0410959A (no)
CA (4) CA2634765A1 (no)
CL (1) CL2004001278A1 (no)
CO (1) CO5660262A2 (no)
CR (1) CR8163A (no)
CU (1) CU23490B7 (no)
EC (1) ECSP056253A (no)
IL (1) IL171941A0 (no)
ME (1) MEP32308A (no)
MX (1) MXPA05012345A (no)
NO (1) NO20055417L (no)
NZ (1) NZ543591A (no)
PE (1) PE20050206A1 (no)
RS (1) RS20050884A (no)
RU (1) RU2322971C2 (no)
TW (1) TW200505424A (no)
UA (1) UA81499C2 (no)
UY (1) UY28330A1 (no)
WO (1) WO2004103369A1 (no)
ZA (1) ZA200509515B (no)

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Publication number Priority date Publication date Assignee Title
NO339631B1 (no) * 2004-10-08 2017-01-16 Indena Spa Semisynteseprosess for fremstillingen av 10-deacetyl-N-debenzoyl-paklitaxel.

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WO2006099396A2 (en) * 2005-03-11 2006-09-21 The Regents Of The University Of Colorado Histone deacetylase inhibitors sensitize cancer cells to epidermal growth factor inhibitors
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CN101263121A (zh) 2005-07-14 2008-09-10 塔克达圣地亚哥公司 组蛋白脱乙酰基酶抑制剂
EP1991247B1 (en) 2006-02-14 2015-10-14 President and Fellows of Harvard College Bifunctional histone deacetylase inhibitors
JP5409015B2 (ja) * 2006-02-14 2014-02-05 プレジデント アンド フェロウズ オブ ハーバード カレッジ ヒストンデアセチラーゼ阻害剤
AU2007248656B2 (en) 2006-05-03 2013-04-04 Dana-Farber Cancer Institute, Inc. Histone deacetylase and tubulin deacetylase inhibitors
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US9408816B2 (en) 2006-12-26 2016-08-09 Pharmacyclics Llc Method of using histone deacetylase inhibitors and monitoring biomarkers in combination therapy
US20090131367A1 (en) * 2007-11-19 2009-05-21 The Regents Of The University Of Colorado Combinations of HDAC Inhibitors and Proteasome Inhibitors
AU2008338631A1 (en) * 2007-12-14 2009-06-25 Georgetown University Histone deacetylase inhibitors
EP2321264B1 (en) 2008-07-23 2016-05-04 President and Fellows of Harvard College Deacetylase inhibitors and uses thereof
GB2462893B (en) * 2008-08-29 2010-10-13 Bayer Schering Pharma Ag N-(2-aminophenyl)-4-[N-(pyridine-3-yl)-methoxycarbonyl-aminomethyl]-benzamide (MS-275) polymorph B
HRP20120183T8 (en) * 2008-08-29 2012-11-30 Bayer Pharma Aktiengesellschaft N-(2-aminophenyl)-4-[n-(pyridine-3-yl)-methoxycarbonyl-aminomethyl]-benzamide (ms-275)polymorph b
AU2009327357C1 (en) 2008-12-19 2017-02-02 Vertex Pharmaceuticals Incorporated Pyrazine derivatives useful as inhibitors of ATR kinase
US20120034302A1 (en) * 2009-02-11 2012-02-09 Liangping Yu Particulate composition and the method of making the same
JP2012525371A (ja) * 2009-05-01 2012-10-22 オンコザイム・ファーマ・インコーポレイテッド 癌を治療するためのペンタミジンの組み合わせ
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WO2011019393A2 (en) 2009-08-11 2011-02-17 President And Fellows Of Harvard College Class- and isoform-specific hdac inhibitors and uses thereof
SG178873A1 (en) * 2009-08-25 2012-04-27 Abraxis Bioscience Llc Combination therapy with nanoparticle compositions of taxane and hedgehog inhibitors
MX2012013081A (es) 2010-05-12 2013-05-09 Vertex Pharma Compuestos utiles como inhibidores de cinasa atr.
KR101892788B1 (ko) 2011-09-13 2018-08-28 파마싸이클릭스 엘엘씨 벤다무스틴과 조합된 히스톤 디아세틸라제 억제제의 제제 및 그의 용도
SG11201401095YA (en) * 2011-09-30 2014-04-28 Vertex Pharma Treating pancreatic cancer and non-small cell lung cancer with atr inhibitors
RS59337B1 (sr) 2011-09-30 2019-10-31 Vertex Pharma Postupak za izradu jedinjenja, korisnih kao inhibitori atr kinaze
WO2013085902A1 (en) * 2011-12-05 2013-06-13 The University Of Texas M.D. Combination therapy methods for treating an inflammatory breast cancer
ES2654670T3 (es) 2012-04-05 2018-02-14 Vertex Pharmaceuticals Incorporated Compuestos útiles como inhibidores de la cinasa ATR y terapias de combinación de los mismos
WO2014055756A1 (en) 2012-10-04 2014-04-10 Vertex Pharmaceuticals Incorporated Method for measuring atr inhibition mediated increases in dna damage
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TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO339631B1 (no) * 2004-10-08 2017-01-16 Indena Spa Semisynteseprosess for fremstillingen av 10-deacetyl-N-debenzoyl-paklitaxel.

Also Published As

Publication number Publication date
RU2005140570A (ru) 2006-06-10
IL171941A0 (en) 2006-04-10
BRPI0410959A (pt) 2006-07-04
UA81499C2 (en) 2008-01-10
CO5660262A2 (es) 2006-07-31
MEP32308A (en) 2010-10-10
TW200505424A (en) 2005-02-16
CA2634765A1 (en) 2004-12-02
CA2634766A1 (en) 2004-12-02
CN1794991A (zh) 2006-06-28
AU2004241873B2 (en) 2008-05-08
US20070098816A1 (en) 2007-05-03
WO2004103369A1 (en) 2004-12-02
ZA200509515B (en) 2006-07-26
UY28330A1 (es) 2004-12-31
EP1626719A1 (en) 2006-02-22
CA2634709A1 (en) 2004-12-02
RU2322971C2 (ru) 2008-04-27
PE20050206A1 (es) 2005-03-26
CU23490B7 (es) 2010-02-23
JP2006526031A (ja) 2006-11-16
AU2004241873A1 (en) 2004-12-02
NO20055417D0 (no) 2005-11-16
ECSP056253A (es) 2006-10-25
CL2004001278A1 (es) 2005-05-06
AU2004241873B8 (en) 2008-05-29
CN101322707A (zh) 2008-12-17
RS20050884A (sr) 2008-04-04
CR8163A (es) 2006-07-14
CA2527191A1 (en) 2004-12-02
KR20060009371A (ko) 2006-01-31
MXPA05012345A (es) 2006-02-08
AR045318A1 (es) 2005-10-26
AU2004241873C1 (en) 2009-01-22
KR100938712B1 (ko) 2010-01-25
NZ543591A (en) 2009-09-25

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