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TWI318629B - Process for decreasing aggregate levels of pegylated protein - Google Patents

Process for decreasing aggregate levels of pegylated protein

Info

Publication number
TWI318629B
TWI318629B TW92126051A TW92126051A TWI318629B TW I318629 B TWI318629 B TW I318629B TW 92126051 A TW92126051 A TW 92126051A TW 92126051 A TW92126051 A TW 92126051A TW I318629 B TWI318629 B TW I318629B
Authority
TW
Taiwan
Prior art keywords
pegylated protein
aggregate levels
decreasing aggregate
decreasing
levels
Prior art date
Application number
TW92126051A
Other languages
English (en)
Other versions
TW200502248A (en
Inventor
Denis M Boyle
John J Buckley
Gary V Johnson
David E Steinmeyer
Michele Toal
Serdar Aykent
Anurag S Rothore
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/646,798 external-priority patent/US20040048315A1/en
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of TW200502248A publication Critical patent/TW200502248A/zh
Application granted granted Critical
Publication of TWI318629B publication Critical patent/TWI318629B/zh

Links

TW92126051A 2002-09-20 2003-09-22 Process for decreasing aggregate levels of pegylated protein TWI318629B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41222702P 2002-09-20 2002-09-20
US10/646,798 US20040048315A1 (en) 2002-08-28 2003-08-25 Method for the preparation of growth hormone and antagonist thereof having lower levels of isoform impurities thereof

Publications (2)

Publication Number Publication Date
TW200502248A TW200502248A (en) 2005-01-16
TWI318629B true TWI318629B (en) 2009-12-21

Family

ID=35864143

Family Applications (1)

Application Number Title Priority Date Filing Date
TW92126051A TWI318629B (en) 2002-09-20 2003-09-22 Process for decreasing aggregate levels of pegylated protein

Country Status (3)

Country Link
AR (1) AR041350A1 (zh)
RU (1) RU2368619C2 (zh)
TW (1) TWI318629B (zh)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3641115A1 (de) * 1986-12-02 1988-06-16 Lentia Gmbh Verfahren zur herstellung eines intravenoes anwendbaren und in fluessiger form stabilen immunglobulins
US5969109A (en) * 1990-02-28 1999-10-19 Bona; Constantin Chimeric antibodies comprising antigen binding sites and B and T cell epitopes
TW517067B (en) * 1996-05-31 2003-01-11 Hoffmann La Roche Interferon conjugates

Also Published As

Publication number Publication date
RU2368619C2 (ru) 2009-09-27
RU2005113152A (ru) 2005-10-27
TW200502248A (en) 2005-01-16
AR041350A1 (es) 2005-05-11

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Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees