TW200503683A - Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain - Google Patents
Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of painInfo
- Publication number
- TW200503683A TW200503683A TW092129615A TW92129615A TW200503683A TW 200503683 A TW200503683 A TW 200503683A TW 092129615 A TW092129615 A TW 092129615A TW 92129615 A TW92129615 A TW 92129615A TW 200503683 A TW200503683 A TW 200503683A
- Authority
- TW
- Taiwan
- Prior art keywords
- methods
- pain
- compositions
- management
- modification
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000002519 immonomodulatory effect Effects 0.000 title abstract 2
- 238000007726 management method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 238000012986 modification Methods 0.000 title 1
- 230000004048 modification Effects 0.000 title 1
- 238000011282 treatment Methods 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000000554 physical therapy Methods 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42100302P | 2002-10-24 | 2002-10-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200503683A true TW200503683A (en) | 2005-02-01 |
Family
ID=32176661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW092129615A TW200503683A (en) | 2002-10-24 | 2003-10-24 | Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1556044A2 (zh) |
| JP (1) | JP2006507284A (zh) |
| KR (1) | KR20050057672A (zh) |
| CN (2) | CN101108185A (zh) |
| AU (1) | AU2003286663B2 (zh) |
| BR (1) | BR0315609A (zh) |
| CA (1) | CA2503536A1 (zh) |
| MX (1) | MXPA05004182A (zh) |
| NZ (1) | NZ540028A (zh) |
| TW (1) | TW200503683A (zh) |
| WO (1) | WO2004037199A2 (zh) |
| ZA (1) | ZA200503240B (zh) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU228769B1 (en) | 1996-07-24 | 2013-05-28 | Celgene Corp | Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha |
| US20050203142A1 (en) * | 2002-10-24 | 2005-09-15 | Zeldis Jerome B. | Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain |
| US7563810B2 (en) | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
| US20050143344A1 (en) * | 2003-12-30 | 2005-06-30 | Zeldis Jerome B. | Methods and compositions using immunomodulatory compounds for the treatment and management of central nervous system disorders or diseases |
| US20050222209A1 (en) * | 2004-04-01 | 2005-10-06 | Zeldis Jerome B | Methods and compositions for the treatment, prevention or management of dysfunctional sleep and dysfunctional sleep associated with disease |
| JP2008534630A (ja) * | 2005-04-08 | 2008-08-28 | ニューロメッド ファーマシューティカルズ リミテッド | 疼痛の軽減のためのn型カルシウムチャネルブロッカーを含む組み合わせ治療の方法 |
| US20070066512A1 (en) * | 2005-09-12 | 2007-03-22 | Dominique Verhelle | Methods and compositions using immunomodulatory compounds for the treatment of disorders associated with low plasma leptin levels |
| JP4382735B2 (ja) * | 2005-10-06 | 2009-12-16 | 独立行政法人科学技術振興機構 | 神経因性疼痛治療剤 |
| CN101495111A (zh) * | 2006-05-26 | 2009-07-29 | 细胞基因公司 | 在联合治疗中使用免疫调节化合物的方法和组合物 |
| CN101557806A (zh) * | 2006-10-19 | 2009-10-14 | 细胞基因公司 | 使用免疫调节化合物治疗和控制螺旋体和其它专性胞内菌疾病的方法和组合物 |
| CN101696205B (zh) | 2009-11-02 | 2011-10-19 | 南京卡文迪许生物工程技术有限公司 | 3-(取代二氢异吲哚-2-基)-2,6-哌啶二酮多晶型物和药用组合物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4215114A (en) * | 1976-11-12 | 1980-07-29 | The Upjohn Company | Analgesic N-[2-(furyl-methylamino and 2-thienylmethylamino)cycloaliphatic]be |
| HU228769B1 (en) * | 1996-07-24 | 2013-05-28 | Celgene Corp | Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha |
| PT925294E (pt) * | 1996-07-24 | 2003-04-30 | Celgene Corp | 2-(2,6-dioxopiperidin-3-il)-ftalimidas e -1-oxoisoindolinas substituidas e metodo de reducao dos niveis de tnf-alfa |
| US6281230B1 (en) * | 1996-07-24 | 2001-08-28 | Celgene Corporation | Isoindolines, method of use, and pharmaceutical compositions |
| US5955476A (en) * | 1997-11-18 | 1999-09-21 | Celgene Corporation | Substituted 2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing inflammatory cytokine levels |
| US20030045552A1 (en) * | 2000-12-27 | 2003-03-06 | Robarge Michael J. | Isoindole-imide compounds, compositions, and uses thereof |
| SE0101256D0 (sv) * | 2001-04-06 | 2001-04-06 | A & Science Invest Ab | Treatment of low back pain |
-
2003
- 2003-10-24 NZ NZ540028A patent/NZ540028A/en unknown
- 2003-10-24 WO PCT/US2003/033757 patent/WO2004037199A2/en not_active Ceased
- 2003-10-24 AU AU2003286663A patent/AU2003286663B2/en not_active Expired - Fee Related
- 2003-10-24 CN CNA2007101039244A patent/CN101108185A/zh active Pending
- 2003-10-24 ZA ZA200503240A patent/ZA200503240B/xx unknown
- 2003-10-24 CA CA002503536A patent/CA2503536A1/en not_active Abandoned
- 2003-10-24 JP JP2004547126A patent/JP2006507284A/ja active Pending
- 2003-10-24 MX MXPA05004182A patent/MXPA05004182A/es active IP Right Grant
- 2003-10-24 BR BR0315609-5A patent/BR0315609A/pt not_active IP Right Cessation
- 2003-10-24 EP EP03777871A patent/EP1556044A2/en not_active Withdrawn
- 2003-10-24 CN CNB2003801075310A patent/CN1326522C/zh not_active Expired - Fee Related
- 2003-10-24 TW TW092129615A patent/TW200503683A/zh unknown
- 2003-10-24 KR KR1020057007000A patent/KR20050057672A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN101108185A (zh) | 2008-01-23 |
| CN1326522C (zh) | 2007-07-18 |
| EP1556044A2 (en) | 2005-07-27 |
| AU2003286663A1 (en) | 2004-05-13 |
| CA2503536A1 (en) | 2004-05-06 |
| BR0315609A (pt) | 2005-08-23 |
| HK1088225A1 (zh) | 2006-11-03 |
| JP2006507284A (ja) | 2006-03-02 |
| MXPA05004182A (es) | 2005-06-08 |
| WO2004037199A3 (en) | 2004-12-23 |
| NZ540028A (en) | 2009-07-31 |
| ZA200503240B (en) | 2007-11-28 |
| KR20050057672A (ko) | 2005-06-16 |
| CN1732000A (zh) | 2006-02-08 |
| WO2004037199A2 (en) | 2004-05-06 |
| AU2003286663B2 (en) | 2009-08-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2005044178A3 (en) | Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain | |
| WO2005046318A3 (en) | Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of asbestos-related diseases and disorders | |
| EP1487461A4 (en) | METHOD FOR THE USE OF COMPOUNDS AND COMPOUNDS WITH IMMUNOMODULATIVE COMPOUNDS FOR THE TREATMENT AND SUPPLY OF MYELODYSPLASTIC SYNDROMES | |
| MXPA05004778A (es) | Metodos de uso y composiciones que contienen compuestos inmunomoduladores para el tratamiento y manejo de enfermedades mieloproliferativas. | |
| WO2005105088A3 (en) | Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of pulmonary hypertension | |
| TW200631578A (en) | Methods and compositions using immunomodulatory compounds for treatment and management of central nervous system injury | |
| WO2004037207A3 (en) | Methods of using and compositions comprising selective cytokine inhibitory drugs for treatment, modification and management of pain | |
| TW200626159A (en) | Therapeutic combinations comprising poly (ADP-ribose) polymerases inhibitor | |
| WO2004039325A3 (en) | Treatment of pain with jnk inhibitors | |
| IL165264A (en) | Protein kinase inhibitors, pharmaceutical compositions comprising them and use thereof in the preparation of medicaments for treating protein kinase-associated diseases | |
| ES2295609T3 (es) | Derivados de tiadiazolilpiperazina utiles para tratar o prevenir un dolor. | |
| IL178591A (en) | 4– (Amino) –2– (2,6 – Dioxo (3-piperidyl)) - Isoindulin – 1,3 – Dion for the treatment and management of myelodysplastic syndromes | |
| TW200503683A (en) | Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain | |
| WO2004034962A3 (en) | Selective cytokine inhibitory drugs for treating myelodysplastic syndrome | |
| WO2004041190A3 (en) | Composition for the treatment of macular degenration | |
| WO2005039497A3 (en) | Methods and compositions comprising thalidomide for treatment of fibromyalgia | |
| TW200420290A (en) | Methods for the treatment, prevention and management of macular degeneration | |
| NO20042758L (no) | Fremgangsmate for behandling av en pasient som krever analgesi. | |
| WO2005046594A3 (en) | Methods of using and compositions comprising a jnk inhibitor for the treatment and management of asbestos-related diseases and disorders | |
| GEP201606538B (en) | Preoperative treatment of post operative pain | |
| WO2004029025A3 (en) | Methods and compositions for the treatment of autoimmune disorders using clofarabine | |
| WO2004041181A3 (en) | Methods of using and compositions comprising selective cytokine inhibitory drugs for treatment and management of macular degeneration | |
| WO2005065372A3 (en) | Methods and compositions using thalidomide for the treatment and management of central nervous system disorders or diseases | |
| WO2005046592A3 (en) | Methods of using and compositions comprising pde4 modulators for the treatment and management of asbestos-related diseases and disorders | |
| NZ542305A (en) | Treatment of proliferative diseases with an epothilone derivative and radiation |