AU2003286663B2 - Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain - Google Patents

Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain Download PDF

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Publication number: AU2003286663B2
Authority: AU; Australia
Prior art keywords: pain; immunomodulatory; immunomodulatory compound; patient; compounds
Prior art date: 2002-10-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

AU2003286663A

Other languages

English (en)

Other versions

AU2003286663A1 (en

Inventor

Herbert Faleck

Donald C. Manning

Jerome B. Zeldis

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Celgene Corp

Original Assignee

Celgene Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-10-24

Filing date

2003-10-24

Publication date

2009-08-13

2003-10-24 Application filed by Celgene Corp filed Critical Celgene Corp

2004-05-13 Publication of AU2003286663A1 publication Critical patent/AU2003286663A1/en

2009-08-13 Application granted granted Critical

2009-08-13 Publication of AU2003286663B2 publication Critical patent/AU2003286663B2/en

2023-10-24 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

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Classifications

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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AU2003286663A 2002-10-24 2003-10-24 Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain Expired - Fee Related AU2003286663B2 (en)

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US42100302P	2002-10-24	2002-10-24
US60/421,003		2002-10-24
PCT/US2003/033757 WO2004037199A2 (en)	2002-10-24	2003-10-24	Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain

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AU2003286663A1 AU2003286663A1 (en)	2004-05-13
AU2003286663B2 true AU2003286663B2 (en)	2009-08-13

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AU2003286663A Expired - Fee Related AU2003286663B2 (en)	2002-10-24	2003-10-24	Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain

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EP (1)	EP1556044A2 (zh)
JP (1)	JP2006507284A (zh)
KR (1)	KR20050057672A (zh)
CN (2)	CN1326522C (zh)
AU (1)	AU2003286663B2 (zh)
BR (1)	BR0315609A (zh)
CA (1)	CA2503536A1 (zh)
MX (1)	MXPA05004182A (zh)
NZ (1)	NZ540028A (zh)
TW (1)	TW200503683A (zh)
WO (1)	WO2004037199A2 (zh)
ZA (1)	ZA200503240B (zh)

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HU228769B1 (en)	1996-07-24	2013-05-28	Celgene Corp	Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha
US20050203142A1 (en) *	2002-10-24	2005-09-15	Zeldis Jerome B.	Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain
US7563810B2 (en)	2002-11-06	2009-07-21	Celgene Corporation	Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases
US20050143344A1 (en) *	2003-12-30	2005-06-30	Zeldis Jerome B.	Methods and compositions using immunomodulatory compounds for the treatment and management of central nervous system disorders or diseases
US20050222209A1 (en) *	2004-04-01	2005-10-06	Zeldis Jerome B	Methods and compositions for the treatment, prevention or management of dysfunctional sleep and dysfunctional sleep associated with disease
JP2008534630A (ja) *	2005-04-08	2008-08-28	ニューロメッドファーマシューティカルズリミテッド	疼痛の軽減のためのｎ型カルシウムチャネルブロッカーを含む組み合わせ治療の方法
US20070066512A1 (en) *	2005-09-12	2007-03-22	Dominique Verhelle	Methods and compositions using immunomodulatory compounds for the treatment of disorders associated with low plasma leptin levels
JP4382735B2 (ja) *	2005-10-06	2009-12-16	独立行政法人科学技術振興機構	神経因性疼痛治療剤
JP2009538318A (ja) *	2006-05-26	2009-11-05	セルジーン・コーポレーション	併用療法において免疫調節化合物を用いる方法及び組成物
CN101557806A (zh) *	2006-10-19	2009-10-14	细胞基因公司	使用免疫调节化合物治疗和控制螺旋体和其它专性胞内菌疾病的方法和组合物
CN101696205B (zh)	2009-11-02	2011-10-19	南京卡文迪许生物工程技术有限公司	3-(取代二氢异吲哚-2-基)-2,6-哌啶二酮多晶型物和药用组合物

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WO2002080891A1 (en) *	2001-04-06	2002-10-17	A+ Science Invest Ab	Use of a tnf inhibitor for the treatment of low back pain

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PL195916B1 (pl) *	1996-07-24	2007-11-30	Celgene Corp	Izomery optyczne podstawionej 1-okso-izoindoliny i 1,3-diokso-izoindoliny, kompozycje farmaceutyczne je zawierające oraz ich zastosowanie
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US20030045552A1 (en) *	2000-12-27	2003-03-06	Robarge Michael J.	Isoindole-imide compounds, compositions, and uses thereof

2003
- 2003-10-24 CN CNB2003801075310A patent/CN1326522C/zh not_active Expired - Fee Related
- 2003-10-24 WO PCT/US2003/033757 patent/WO2004037199A2/en not_active Ceased
- 2003-10-24 KR KR1020057007000A patent/KR20050057672A/ko not_active Ceased
- 2003-10-24 CN CNA2007101039244A patent/CN101108185A/zh active Pending
- 2003-10-24 CA CA002503536A patent/CA2503536A1/en not_active Abandoned
- 2003-10-24 ZA ZA200503240A patent/ZA200503240B/xx unknown
- 2003-10-24 EP EP03777871A patent/EP1556044A2/en not_active Withdrawn
- 2003-10-24 TW TW092129615A patent/TW200503683A/zh unknown
- 2003-10-24 JP JP2004547126A patent/JP2006507284A/ja active Pending
- 2003-10-24 MX MXPA05004182A patent/MXPA05004182A/es active IP Right Grant
- 2003-10-24 AU AU2003286663A patent/AU2003286663B2/en not_active Expired - Fee Related
- 2003-10-24 BR BR0315609-5A patent/BR0315609A/pt not_active IP Right Cessation
- 2003-10-24 NZ NZ540028A patent/NZ540028A/en unknown

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US6316471B1 (en) *	1996-07-24	2001-11-13	Celgene Corporation	Isoindolines, method of use, and pharmaceutical compositions
WO2002080891A1 (en) *	2001-04-06	2002-10-17	A+ Science Invest Ab	Use of a tnf inhibitor for the treatment of low back pain

Also Published As

Publication number	Publication date
BR0315609A (pt)	2005-08-23
AU2003286663A1 (en)	2004-05-13
ZA200503240B (en)	2007-11-28
WO2004037199A2 (en)	2004-05-06
CN1326522C (zh)	2007-07-18
CN1732000A (zh)	2006-02-08
KR20050057672A (ko)	2005-06-16
JP2006507284A (ja)	2006-03-02
CA2503536A1 (en)	2004-05-06
NZ540028A (en)	2009-07-31
HK1088225A1 (zh)	2006-11-03
CN101108185A (zh)	2008-01-23
TW200503683A (en)	2005-02-01
EP1556044A2 (en)	2005-07-27
MXPA05004182A (es)	2005-06-08
WO2004037199A3 (en)	2004-12-23

Publication	Publication Date	Title
US20050203142A1 (en)	2005-09-15	Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain
AU2003284979B2 (en)	2008-07-17	Methods of using and compositions comprising selective cytokine inhibitory drugs for treatment, modification and management of pain
AU2003286663B2 (en)	2009-08-13	Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain
US7612096B2 (en)	2009-11-03	Methods for treatment, modification and management of radiculopathy using 1-oxo-2-(2,6-dioxopiperidin-3yl)-4-aminoisoindoline
US20070161696A1 (en)	2007-07-12	Methods of using and compositions comprising selective cytokine inhibitory drugs for treatment, modification and management of pain
CA2543132A1 (en)	2005-05-19	Methods of using and compositions comprising selective cytokine inhibitory drugs for treatment, modification and management of pain
HK1112414A (zh)	2008-09-05	用於治療、改變和控制疼痛的包含免疫調節化合物的組合物
HK1088225B (zh)	2008-02-22	用於治療、改變和控制疼痛的包含免疫調節化合物的組合物
HK1097771A (zh)	2007-07-06	用於治療、改善和控制疼痛的含有免疫調節化合物的組合物及其使用方法

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